The single-index model is one of the most popular semiparametricmodels in applied quantitative sciences. Two new estimation methodshave been proposed recently by Hristache, Juditski, and Spokoiny(2001, Annals ofStatistics 29, 595–623) and Xia, Tong, Li, and Zhu(2002, Journal of the RoyalStatistical Society, Series B 64, 363–410),respectively. However, their asymptotic distributions have not beeninvestigated yet. In this paper, alternative versions for themethods are investigated. Asymptotic distributions of the estimatorsare derived. Efficiency comparisons between the estimation methodsare made.The author is most gratefulto Professor O. Linton and Professor W. Härdle for helpfuldiscussions. Valuable comments from two anonymous reviewers haveimproved the presentation of the paper substantially. Theresearch has been partially supported by NUS research grantR-155-000-048-112, National University of Singapore, Singapore,and the Alexander von Humboldt Foundation, Germany.