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Vegetarian diets, low-meat diets and health: a review

  • Claire T McEvoy (a1), Norman Temple (a2) and Jayne V Woodside (a1)

To review the epidemiological evidence for vegetarian diets, low-meat dietary patterns and their association with health status in adults.


Published literature review focusing primarily on prospective studies and meta-analyses examining the association between vegetarian diets and health outcomes.


Both vegetarian diets and prudent diets allowing small amounts of red meat are associated with reduced risk of diseases, particularly CHD and type 2 diabetes. There is limited evidence of an association between vegetarian diets and cancer prevention. Evidence linking red meat intake, particularly processed meat, and increased risk of CHD, cancer and type 2 diabetes is convincing and provides indirect support for consumption of a plant-based diet.


The health benefits of vegetarian diets are not unique. Prudent plant-based dietary patterns which also allow small intakes of red meat, fish and dairy products have demonstrated significant improvements in health status as well. At this time an optimal dietary intake for health status is unknown. Plant-based diets contain a host of food and nutrients known to have independent health benefits. While vegetarian diets have not shown any adverse effects on health, restrictive and monotonous vegetarian diets may result in nutrient deficiencies with deleterious effects on health. For this reason, appropriate advice is important to ensure a vegetarian diet is nutritionally adequate especially for vulnerable groups.

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3. WL Beeson , PK Mills , RL Phillips et al. (1989) Chronic disease among Seventh-day Adventists, a low-risk group. Rationale, methodology, and description of the population. Cancer 64, 570581.

4. M Thorogood , J Mann , P Appleby et al. (1994) Risk of death from cancer and ischaemic heart disease in meat and non-meat eaters. BMJ 308, 16671671.

6. R Frentzel-Beyme , J Claude & U Eilber (1988) Mortality among German vegetarians: first results after 5 years of follow up. Nutr Cancer 11, 117126.

10. GE Fraser (2009) Vegetarian diets: what do we know of their effects on common chronic diseases? Am J Clin Nutr 89, issue 5, 1607S1612S.

11.American Dietetic Association (2009) Position of the American Dietetic Association: vegetarian diets. J Am Diet Assoc 109, 12661282.

14. J Chang-Claude , S Hermann , U Elber et al. (2005) Lifestyle determinants and mortality in German vegetarians and health conscious persons: results of a 21 year follow up. Cancer Epidemol Biomarkers Prev 14, 963968.

17. ML Toohey , MA Harris , W DeWitt et al. (1998) Cardiovascular disease risk factors are lower in African-American vegans compared to lacto-ovo-vegetarians. J Am Coll Nutr 17, 425434.

19. RS Cooper , RB Goldberg , M Trevisan et al. (1982) The selective lipid-lowering effect of vegetarianism on low density lipoproteins in a cross-over experiment. Atherosclerosis 44, 293305.

21. HR Ferdowsian & ND Barnard (2009) Effects of plant-based diets on plasma lipids. Am J Cardiol 104, 947956.

22. SM Grundy , JI Cleeman , CN Merz et al. (2004) Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Circulation 110, 227239.

23. PN Appleby , GK Davey & TJ Key (2002) Hypertension and blood pressure among meat eaters, fish eaters, vegetarians and vegans in EPIC–Oxford. Public Health Nutr 5, 645654.

24. GK Davey , EA Spencer , PN Appleby et al. (2003) EPIC–Oxford: lifestyle characteristics and nutrient intakes in a cohort of 33 883 meat-eaters and 31 546 non meat-eaters in the UK. Public Health Nutr 6, 259269.

26. EA Spencer , PN Appleby , GK Davey et al. (2003) Diet and body mass index in 38,000 EPIC–Oxford meat eaters, fish eaters, vegetarians and vegans. Int J Obes Relat Metab Disord 27, 728734.

28. M Rosell , PN Appleby , EA Spencer et al. (2006) Weight gain over 5 years in 21,966 meat-eating, fish-eating, vegetarian, and vegan men and women in EPIC–Oxford. Int J Obes (Lond) 30, 13891396.

29. GM Turner-McGrievy , ND Barnard & AR Scialli (2007) A two-year randomized weight loss trial comparing a vegan diet to a more moderate low-fat diet. Obesity (Silver Spring) 15, 22762281.

30. TJ Key , PN Appleby , EA Spencer et al. (2009) Cancer incidence in British vegetarians. Br J Cancer 101, 192197.

31. TJ Key , PN Appleby , EA Spencer et al. (2009) Cancer incidence in vegetarians: results from the European Prospective Investigation into Cancer and Nutrition (EPIC–Oxford). Am J Clin Nutr 89, issue 5, 1620S1626S.

32. EF Taylor , VJ Burley , DC Greenwood et al. (2007) Meat consumption and risk of breast cancer in the UK Women's Cohort Study. Br J Cancer 96, 11391146.

34. S Tonstad , T Butler , R Yan et al. (2009) Type of vegetarian diet, body weight, and prevalence of type 2 diabetes. Diabetes Care 32, 791796.

35. RJ Barnard , T Jung & SB Inkeles (1994) Diet and exercise in the treatment of NIDDM: the need for early emphasis. Diabetes Care 17, 14691472.

37. ND Barnard , J Cohen , DJ Jenkins et al. (2009) A low-fat vegan diet and a conventional diabetes diet in the treatment of type 2 diabetes: a randomized, controlled, 74-wk clinical trial. Am J Clin Nutr 89, issue 5, 1588S1596S.

38. P Boffetta , E Couto , J Wichmann et al. (2010) Fruit and vegetable intake and overall cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). J Natl Cancer Inst 102, 529537.

39. CA Gonzalez & E Riboli (2006) Diet and cancer prevention: where we are, where we are going. Nutr Cancer 56, 225231.

40. TJ Key , A Schatzkin , WC Willett et al. (2004) Diet, nutrition and the prevention of cancer. Public Health Nutr 7, 187200.

43. FJ He , CA Nowson & GA MacGregor (2006) Fruit and vegetable consumption and stroke: meta-analysis of cohort studies. Lancet 367, 320326.

44. FJ He , CA Nowson , M Lucas et al. (2007) Increased consumption of fruit and vegetables is related to a reduced risk of coronary heart disease: meta-analysis of cohort studies. J Hum Hypertens 21, 717728.

45. P Carter , LJ Gray , J Troughton et al. (2010) Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis. BMJ 341, c4229.

46. S Liu , M Serdula , SJ Janket et al (2004) A prospective study of fruit and vegetable intake and the risk of type 2 diabetes in women. Diabetes Care 27, 29932996.

47. D Mozaffarian , R Micha & S Wallace (2010) Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: a systematic review and meta-analysis of randomized controlled trials. PLoS Med 7, e1000252.

49. J Sabaté , K Oda & E Ros (2010) Nut consumption and blood lipid levels: a pooled analysis of 25 intervention trials. Arch Intern Med 170, 821827.

50. K Reynolds , A Chin , KA Lees et al. (2006) A meta-analysis of the effect of soy protein supplementation on serum lipids. Am J Cardiol 98, 633640.

51. CS Patch , LC Tapsell & PG Williams (2005) Plant sterol/stanol prescription is an effective treatment strategy for managing hypercholesterolemia in outpatient clinical practice. J Am Diet Assoc 105, 4652.

52. M Law (2000) Plant sterol and stanol margarines and health. BMJ 320, 861864.

53. BJ Trock , L Hilakivi-Clarke & R Clarke (2006) Meta-analysis of soy intake and breast cancer risk. J Natl Cancer Inst 98, 459471.

54. LQ Qin , JY Xu , PY Wang et al. (2006) Soyfood intake in the prevention of breast cancer risk in women: a meta-analysis of observational epidemiological studies. J Nutr Sci Vitaminol (Tokyo) 52, 428436.

55. AH Wu , WP Koh , R Wang et al. (2008) Soy intake and breast cancer risk in Singapore Chinese Health Study. Br J Cancer 99, 196200.

56. LS Velentzis , MM Cantwell , C Cardwell et al. (2009) Lignans and breast cancer risk in pre- and post-menopausal women: meta-analyses of observational studies. Br J Cancer 100, 14921498.

57. K Buck , AK Zaineddin , A Vrieling et al. (2010) Meta-analyses of lignans and enterolignans in relation to breast cancer risk. Am J Clin Nutr 92, 141153.

58. KT Knoops , LC de Groot , D Kromhout et al. (2004) Mediterranean diet, lifestyle factors, and 10-year mortality in elderly European men and women: the HALE project. JAMA 292, 14331439.

59. PN Mitrou , V Kipnis , AC Thiébaut et al. (2007) Mediterranean dietary pattern and prediction of all-cause mortality in a US population: results from the NIH–AARP Diet and Health Study. Arch Intern Med 167, 24612468.

60. A Trichopoulou , T Costacou , C Bamia et al. (2003) Adherence to a Mediterranean diet and survival in a Greek population. New Engl J Med 348, 25992608.

61. F Sofi , F Cesari , R Abbate et al. (2008) Adherence to Mediterranean diet and health status: meta-analysis. BMJ 337, a1344.

62. M de Lorgeril , P Salen , JL Martin et al. (1999) Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study. Circulation 99, 779785.

63. LJ Appel , TJ Moore , E Obarzanek et al. (1997) A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med 336, 11171124.

64. LJ Appel (2003) Lifestyle modification as a means to prevent and treat high blood pressure. J Am Soc Nephrol 14, Suppl. 2, S99S102.

65. TT Fung , SE Chiuve , ML McCullough et al. (2008) Adherence to a DASH-style diet and risk of coronary heart disease and stroke in women. Arch Intern Med 168, 713720.

66. R Sinha , AJ Cross , BI Graubard et al. (2009) Meat intake and mortality: a prospective study of over half a million people. Arch Intern Med 169, 562571.

67. R Micha , SK Wallace & D Mozaffarian (2010) Red and processed meat consumption and risk of incident coronary heart disease, stroke, and diabetes mellitus: a systematic review and meta-analysis. Circulation 121, 22712283.

68. AR Mangels & V Messina (2001) Considerations in planning vegan diets: infants. J Am Diet Assoc 101, 670677.

69. V Messina & AR Mangels (2001) Considerations in planning vegan diets: children. J Am Diet Assoc 101, 661669.

71. SP Stabler & RH Allen (2004) Vitamin B12 deficiency as a worldwide problem. Annu Rev Nutr 24, 299326.

72. YC Huang , SJ Chang , YT Chiu et al. (2003) The status of plasma homocysteine and related B-vitamins in healthy young vegetarians and nonvegetarians. Eur J Nutr 42, 8490.

75. P Autier & S Gandini (2007) Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Arch Intern Med 167, 17301737.

76. E Giovannucci , Y Liu & WC Willett (2006) Cancer incidence and mortality and vitamin D in black and white male health professionals. Cancer Epidemiol Biomarkers Prev 15, 24672472.

77. DL Trump , KK Deeb & CS Johnson (2010) Vitamin D: considerations in the continued development as an agent for cancer prevention and therapy. Cancer J 16, 19.

79. WJ Craig (2009) Health effects of vegan diets. Am J Clin Nutr 89, issue 5, 1627S1633S.

80. TAB Sanders (2009) DHA status of vegetarians. Prostaglandins Leukot Essent Fatty Acids 81, 137141.

81. M Kornsteiner , I Singer & I Elmadfa (2008) Very low n-3 long-chain polyunsaturated fatty acid status in Austrian vegetarians and vegans. Ann Nutr Metab 52, 3747.

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