Hostname: page-component-77f85d65b8-6bnxx Total loading time: 0 Render date: 2026-03-27T08:18:25.241Z Has data issue: false hasContentIssue false
  • English
  • Français

Phenotypic programming as a distal cause of resilience

Published online by Cambridge University Press:  02 September 2015

Esther Nederhof
Esther Nederhof*
Affiliation:
University of Groningen, University Medical Center Groningen, Interdisciplinary Center Psychopathology and Emotion Regulation, 9700 RB Groningen, The Netherlands. e.nederhof@umcg.nl www.rug.nl/staff/e.nederhof
Get access Rights & Permissions [Opens in a new window]

Abstract

During early childhood, individuals with high sensitivity to early programming adjust their phenotype in a way that is expected to be adaptive in their later environment. These adaptations are hypothesized to result in resilience in environments that match the early environment. As appraisal style is a putative target of adaptive programming, early experiences could be a distal cause of resilience.

Information

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 38 , 2015 , e115
Copyright
Copyright © Cambridge University Press 2015 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Andersen, S. L. (2003) Trajectories of brain development: Point of vulnerability or window of opportunity? Neuroscience and Biobehavioral Reviews 27(1–2):3–18. doi: 10.1016/S0149-7634(03)00005-8.CrossRefGoogle ScholarPubMed
Belsky, J., Bakermans-Kranenburg, M. J. & van IJzendoorn, M. H. (2007) For better and for worse: Differential susceptibility to environmental influences. Current Directions in Psychological Science 16(6):300–304.CrossRefGoogle Scholar
Biggio, F., Pisu, M. G., Garau, A., Boero, G., Locci, V., Mostallino, M. C., Olla, P., Utzeri, C. & Serra, M. (2014) Maternal separation attenuates the effect of adolescent social isolation on HPA axis responsiveness in adult rats. European Neuropsychopharmacology 24(7):1152–61. doi: 10.1016/j.euroneuro.2014.03.009.CrossRefGoogle ScholarPubMed
Boyce, W. T. & Ellis, B. J. (2005) Biological sensitivity to context: I. An evolutionary-developmental theory of the origins and functions of stress reactivity. Development and Psychopathology 17(2):271–301. doi: 10.1017/S0954579405050145.CrossRefGoogle ScholarPubMed
Brody, G. H., Yu, T., Chen, E., Miller, G. E., Kogan, S. M. & Beach, S. R. H. (2013) Is resilience only skin deep? Rural African Americans' socioeconomic status-related risk and competence in preadolescence and psychological adjustment and allostatic load at age 19. Psychological Science 24(7):1285–93. doi: 10.1177/0956797612471954.CrossRefGoogle ScholarPubMed
Champagne, D. L., Bagot, R. C., van Hasselt, F., Ramakers, G., Meaney, M. J., de Kloet, E. R., Joëls, M. & Krugers, H. (2008) Maternal care and hippocampal plasticity: Evidence for experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to glucocorticoids and stress. Journal of Neuroscience 28(23):6037–45. doi: 10.1523/JNEUROSCI.0526-08.2008.CrossRefGoogle ScholarPubMed
Daskalakis, N. P., Oitzl, M. S., Schachinger, H., Champagne, D. L. & de Kloet, E. R. (2012) Testing the cumulative stress and mismatch hypotheses of psychopathology in a rat model of early-life adversity. Physiology and Behavior 106(5):707–21. doi: 10.1016/j.physbeh.2012.01.015.CrossRefGoogle Scholar
Del Giudice, M., Ellis, B. J. & Shirtcliff, E. A. (2011) The adaptive calibration model of stress responsivity. Neuroscience and Biobehavioral Reviews 35:1562–92.CrossRefGoogle ScholarPubMed
Ellis, B. J., Boyce, W. T., Belsky, J., Bakermans-Kranenburg, M. J. & van Ijzendoorn, M. H. (2011) Differential susceptibility to the environment: An evolutionary-neurodevelopmental theory. Development and Psychopathology 23(1):7–28.CrossRefGoogle Scholar
Ellis, B. J. & Del Giudice, M. (2014) Beyond allostatic load: Rethinking the role of stress in regulating human development. Development and Psychopathology 26(1):1–20. doi: 10.1017/S0954579413000849.CrossRefGoogle ScholarPubMed
Frankenhuis, W. E. & Del Giudice, M. (2012) When do adaptive developmental mechanisms yield maladaptive outcomes? Developmental Psychology 48(3):628–42. doi: 10.1037/a0025629; 10.1037/a0025629.CrossRefGoogle ScholarPubMed
Frankenhuis, W. E. & Panchanathan, K. (2011) Balancing sampling and specialization: An adaptationist model of incremental development. Proceedings of the Royal Society B – Biological Sciences 278(1724):3558–65. doi: 10.1098/rspb.2011.0055.CrossRefGoogle ScholarPubMed
Gluckman, P. D., Hanson, M. A. & Beedle, A. S. (2007) Early life events and their consequences for later disease: A life history and evolutionary perspective. American Journal of Human Biology 19(1):1–19.CrossRefGoogle ScholarPubMed
Ivy, A. S., Brunson, K. L., Sandman, C. & Baram, T. Z. (2008) Dysfunctional nurturing behavior in rat dams with limited access to nesting material: A clinically relevant model for early-life stress. Neuroscience 154(3):1132–42. doi: 10.1016/j.neuroscience.2008.04.019.CrossRefGoogle ScholarPubMed
Kuzawa, C. W. (2005) Fetal origins of developmental plasticity: Are fetal cues reliable predictors of future nutritional environments? American Journal of Human Biology 17(1):5–21.CrossRefGoogle ScholarPubMed
Lupien, S. J., McEwen, B. S., Gunnar, M. R. & Heim, C. (2009) Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nature Reviews Neuroscience 10(6):434–45.CrossRefGoogle ScholarPubMed
Nederhof, E., Ormel, J. & Oldehinkel, A. J. (2014) Mismatch or cumulative stress: The pathway to depression is conditional on attention style. Psychological Science 25(3):684–92. doi: 10.1177/0956797613513473.CrossRefGoogle ScholarPubMed
Nederhof, E. & Schmidt, M. V. (2012) Mismatch or cumulative stress: Toward an integrated hypothesis of programming effects. Physiology and Behavior 106(5):691–700. doi: 10.1016/j.physbeh.2011.12.008.CrossRefGoogle ScholarPubMed
Oldehinkel, A. J., Ormel, J., Verhulst, F. C. & Nederhof, E. (2014) Childhood adversities and adolescent depression: A matter of both risk and resilience. Development and Psychopathology 26(4, Pt.1) 1067–75. doi: 10.1017/S0954579414000534.CrossRefGoogle ScholarPubMed
Santarelli, S., Lesuis, S. L., Wang, X., Wagner, K. V., Hartmann, J., Labermaier, C., Scharf, S. H., Müller, M. B., Holsboer, F. & Schmidt, M. V. (2014) Evidence supporting the match/mismatch hypothesis of psychiatric disorders. European Neuropsychopharmacology 24(6):907–18. doi: 10.1016/j.euroneuro.2014.02.002.CrossRefGoogle ScholarPubMed
Van den Hove, D. L. A., Leibold, N. K., Strackx, E., Martinez-Claros, M., Lesch, K. P., Steinbusch, H. W. M., Schruers, K. R. J. & Prickaerts, J. (2014) Prenatal stress and subsequent exposure to chronic mild stress in rats; interdependent effects on emotional behavior and the serotonergic system. European Neuropsychopharmacology 24(4):595–607. doi: 10.1016/j.euroneuro.2013.09.006.CrossRefGoogle ScholarPubMed
Zalosnik, M. I., Pollano, A., Trujillo, V., Suarez, M. M. & Durando, P. E. (2014) Effect of maternal separation and chronic stress on hippocampal-dependent memory in young adult rats: Evidence for the match-mismatch hypothesis. Stress: The International Journal on the Biology of Stress 17(5):445–50. doi: 10.3109/10253890.2014.936005.CrossRefGoogle ScholarPubMed