This chapter examines how various civil rights movements have interwoven the Declaration into their advocacy for causes to combat social and legal discrimination, including chauvinism, labor exploitation, and election plutocracy. A variety of groups, including first-wave feminists and labor advocates, effectively relied on it to promote various constitutional causes. Among suffragettes, its statement of human equality stood out, while workers’ movements favored the document’s condemnation of autocracy and oppression. As with other groups who likewise relied on the Declaration’s mandates, it represented a national commitment toward achieving a liberal equality for the common good. The Declaration of Independence remains relevant today to matters as broad in constitutional scope as federalism, campaign financing, AI advertisement, and separation of powers. Its sweeping statement of unalienable human rights and equality continues to embody core American commitments to representative democracy. That manifesto of equality and freedom has for two centuries influenced politicians, civil rights organizations, and ordinary people in the United States and abroad.