Manual of Botulinum Toxin Therapy

doi:10.1017/CBO9781139178068

Fully updated throughout, the second edition of the Manual of Botulinum Toxin Therapy provides practical guidance on the use of Botox in a wide variety of disorders. New chapters have been added on the use of botulinum toxin in wound healing, in focal hand dystonia and in thoracic outlet syndrome, as well as others. There are new chapters on the use of botulinum toxins in conjunction with ultrasound guidance. Using clear line-drawings the Manual describes the relevant injection sites for each condition and gives comparative dosage tables for the various formulations of toxins used in different muscle groups. Throughout the emphasis is on technique and the book can be used as both a teaching aid and in bedside guidance. The manual will be of use to neurologists, otolaryngologists, urologists, ophthalmologists, dermatologists, internists, pain management specialists, rehabilitation specialists and plastic surgeons, and any other clinicians discovering the potential of botulinum toxin.

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Contents

Frontmatter
pp i-iv
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Dedication
pp v-vi
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Contents
pp vii-viii
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List of Contributors
pp ix-xii
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Preface
pp xiii-xiv
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Chapter 1 - The pretherapeutic history of botulinum neurotoxin
pp 1-7
- By Frank J. Erbguth, Department of Neurology, Nuremberg Municipal Academic Hospital, Nuremberg, Germany
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Chapter 2 - Botulinum neurotoxin: history of clinical development
pp 8-11
- By Daniel Truong, The Parkinson’s and Movement Disorders Institute, Fountain Valley, California , Mark Hallett, George Washington University School of Medicine and Health Sciences, Washington, DC
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Chapter 3 - Pharmacology of botulinum neurotoxins
pp 12-15
- By Daniel Truong, The Parkinson’s and Movement Disorders Institute, Fountain Valley, California , Mark Hallett, George Washington University School of Medicine and Health Sciences, Washington, DC
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Chapter 4 - Immunological properties of botulinum neurotoxins
pp 16-21
- By Hans Bigalke, Institute of Toxicology, Hannover Medical School, Hannover, Germany, Dirk Dressler, Movement Disorder Section, Department of Neurology, Hannover Medical School, Hannover, Germany, Jürgen Frevert, Institute of Toxicology, Hannover Medical School, Hannover, Germany
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Chapter 5 - Treatment of cervical dystonia
pp 22-34
- By Daniel Truong, The Parkinson’s and Movement Disorders Institute, Fountain Valley, California , Karen Frei, The Parkinson and Movement Disorder Institute, Orange Coast Memorial Center, Fountain Valley, CA, USA, Cynthia L. Comella, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA
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Chapter 6 - Examination and treatment of complex cervical dystonia
pp 35-45
- By Gerhard Reichel, Center for Movement Disorders, Clinic Paracelsus, Zwickau, Germany
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Chapter 7 - Ultrasound guidance for botulinum neurotoxin therapy: cervical dystonia
pp 46-59
- By Katharine E. Alter, Mount Washington Pediatric Hospital, Baltimore, MD, USA
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Chapter 8 - Treatment of blepharospasm
pp 60-63
- By Carlo Colosimo, Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy, Dorina Tiple, Dipartimento di Biologia Cellulare Neuroscienze, Istituto Superiore di Sanita, Roma, Italy, Alfredo Berardelli, Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy
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Chapter 9 - Botulinum neurotoxin in oromandibular dystonia
pp 64-70
- By Roongroj Bhidayasiri, Chulalongkorn Center of Excellence on Parkinson’s Disease and Related Disorders, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand, Francisco Cardoso, Departament of Clinical Medine, Universidade Federal de Minas Gerais Belo Horizonte, Minas Gerais, Brazil, Daniel Truong, The Parkinson’s and Movement Disorders Institute, Fountain Valley, California
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Chapter 10 - Treatment of focal hand dystonia
pp 71-84
- By Barbara Illowsky Karp, Combined NeuroScience IRB, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, Chandi Das, Neurology Department, Canberra Hospital, Garren Act Health, ACT, Australia, Daniel Truong, The Parkinson’s and Movement Disorders Institute, Fountain Valley, California, Mark Hallett, George Washington University School of Medicine and Health Sciences, Washington, DC
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Chapter 11 - Botulinum neurotoxin therapy of laryngeal muscle hyperactivity syndromes
pp 85-91
- By Daniel Truong, The Parkinson’s and Movement Disorders Institute, Fountain Valley, California, Arno Olthoff, Department of Phoniatrics and Pediatric Audiology, University of Göttingen, Göttingen, Germany, Rainer Laskawi, Department of Otolaryngology, Head and Neck Surgery, University of Göttingen, Göttingen, Germany
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Chapter 12 - The use of botulinum neurotoxin in otorhinolaryngology
pp 92-100
- By Rainer Laskawi, Department of Otolaryngology, Head and Neck Surgery, University of Göttingen, Göttingen, Germany, Arno Olthoff, Department of Phoniatrics and Pediatric Audiology, University of Göttingen, Göttingen, Germany, Oleg Olegovich Ivanov, Department of Neurology for Stroke Patients, City Clinical Hospital Number 1, Novokuznetsk, Russia
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Chapter 13 - Treatment of hemifacial spasm
pp 101-106
- By Karen Frei, The Parkinson and Movement Disorder Institute, Orange Coast Memorial Center, Fountain Valley, CA, USA
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Chapter 14 - Spasticity
pp 107-118
- By Mayank S. Pathak, The Parkinson and Movement Disorder Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA, Allison Brashear, Department of Neurology, Wake Forest University Baptist Medical Center, Winston-Salem, NC, USA
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Chapter 15 - The use of botulinum neurotoxin in spastic infantile cerebral palsy
pp 119-127
- By Ann Tilton, Louisiana State University Health Sciences Center, New Orleans, LA, USA, H. Kerr Graham, University of Melbourne, Royal Children’s Hospital, Parkville, Victoria, Australia
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Chapter 16 - The role of ultrasound for botulinum neurotoxin injection in childhood spasticity
pp 128-132
- By Bettina Westhoff, Department of Orthopaedics, Heinrich-Heine-University Hospital, Duesseldorf, Germany
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Chapter 17 - The use of botulinum neurotoxin in spasticity using ultrasound guidance
pp 133-159
- By Andrea Santamato, Department of Physical Medicine and Rehabilitation, “OORR” Hospital, University of Foggia, Foggia, Italy, Franco Molteni, Valduce Hospital, Villa Beretta, Rehabilitation Center, Costa Masnaga, Lecco, Italy, Pietro Fiore, Department of Physical Medicine and Rehabilitation, “Policlinico Hospital” Bari and University of Foggia, Foggia, Italy
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Chapter 18 - The use of botulinum neurotoxin in tic disorders and essential hand and head tremor
pp 160-167
- By Joseph Jankovic, Parkinson’s Disease Center and Movement Disorder Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX, USA
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Chapter 19 - Treatment of stiff-person syndrome with botulinum neurotoxin
pp 168-173
- By Diana Richardson, Department of Neurology, Yale University School of Medicine, New Haven, CT, USA, Bahman Jabbari, Department of Neurology, Yale University School of Medicine, New Haven, CT, USA
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Chapter 20 - Botulinum neurotoxin applications in ophthalmology
pp 174-180
- By Peter Roggenkamper, Department of Ophthalmology, University of Bonn, Bonn, Germany, Alan Scott, Strabismus Research Institute, San Francisco, CA, USA
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Chapter 21 - Cosmetic uses of botulinum neurotoxins
pp 181-193
- By Joshua Spanogle, Department of Dermatology, University of California, Irvine, Irvine, CA, USA, Dee Anna Glaser, Department of Dermatology, Saint Louis University School of Medicine, St. Louis, MO, USA, Christopher Zachary, Department of Dermatology, University of California, Irvine
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Chapter 22 - Hyperhidrosis
pp 194-202
- By Henning Hamm, Department of Dermatology, University of Würzburg, Würzburg, Germany, Markus K. Naumann, Department of Neurology, Augsburg Hospital, Augsburg, Germany
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Chapter 23 - Botulinum neurotoxin A treatment for ischemic digits
pp 203-209
- By Michael W. Neumeister, Department of Plastic Surgery, Southern Illinois University School of Medicine, Carbondale, IL, USA, Kelli Webb, Department of Plastic Surgery, Southern Illinois University School of Medicine, Carbondale, IL, USA
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Chapter 24 - Botulinum neurotoxin in wound healing
pp 210-215
- By Holger G. Gassner, Department of Otolaryngology, University of Regensburg, Regensburg, Germany
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Chapter 25 - Use of botulinum neurotoxin in neuropathic pain
pp 216-221
- By Szu-Kuan Yang, Department of Neurology, Shuang-Ho Hospital, Taipei Medical University, New Taipei City, Taiwan, Chaur-Jong Hu, Department of Neurology, Shuang-Ho Hospital, Taipei Medical University, New Taipei City, Taiwan
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