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Chapter 13 - Medication-Resistant Epilepsy Syndromes in Children

Published online by Cambridge University Press:  20 August 2020

John M. Stern
Affiliation:
Geffen School of Medicine at UCLA, Los Angeles, CA
Raman Sankar
Affiliation:
Geffen School of Medicine at UCLA, Los Angeles, CA
Michael Sperling
Affiliation:
Jefferson Hospital for Neurosciences, Philadelphia, PA
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Summary

Medically refractory epilepsies account for 20–30% of the patients evaluated in an epilepsy centre. With more than 50% of paediatric epilepsies persisting into adulthood, it is very important for the epileptologist to have an updated understanding of the current advances in the field of medically refractory paediatric epileptic syndromes.

Refractory epilepsies are common in children. Medical intractability becomes quickly apparent after seizure onset in children with developmental epileptic encephalopathies [1].

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