Published online by Cambridge University Press: 23 December 2009
Introduction
It is not possible in a book with this format to discuss the treatment details for each tumour type, stage and subsite. This chapter highlights treatment principles and controversies.
This chapter covers the anatomical sites of the lip, oral cavity, pharynx, larynx, nose, paranasal sinuses, salivary glands, middle ear and squamous carcinoma of unknown primary. The first section considers general features of head and neck cancer. Subsequent sections focus on specific tumour sites.
General features of head and neck tumours
Types of head and neck tumour
The majority of head and neck cancers are squamous carcinomas, which account for 90% of all cases. The range of tumours is shown in Table 8.1.
Incidence and epidemiology of head and neck tumours
Approximately 8000 new cases occur per year in England and Wales (CRUK, 2004).
Approximately 3000 deaths occur per year in England and Wales (CRUK, 2004).
The UK annual incidence is approximately 14/100,000 cases per year (CRUK, 2004).
Regional variation in the UK is 8 per 100,000 in the Thames region compared to 13 to 15 per 100,000 in Wales and northwest England (NICE, 2004).
Head and neck tumours are more common in males than females (male-to-female ratio of 2:1), except for salivary gland tumours.
Incidence increases from middle age, with peak incidence occurring in the 60- to 75-age group.
Risk factors and aetiology for head and neck tumours
Prolonged exposure to environmental factors plays a key role.
To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Find out more about the Kindle Personal Document Service.
To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.
To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.