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To map Greek academic otolaryngologists, and assess gender, age and location-related differences in their rank and academic productivity.
Methods
A pre-established database of local and diaspora scientists was used, after adjustment and updating for otolaryngology. The following data were recorded: age, gender, academic rank, country of work, total citations and h-index of December 2022.
Results
A total of 276 Greek academic otolaryngologists were identified in the Scopus database. Of Greek otolaryngologists, 15.9 per cent are women. Of all academic otolaryngologists, 27.1 per cent have a university post, but only 4 per cent of them are women. There is an almost linear correlation between university post ranking and citations. Otolaryngologists based in Greece accounted for 3 out of the 10 most cited Greek otolaryngologists.
Conclusion
There are significant age, gender and location-related differences in academic output. The representation of women and the full use of their potential in medicine require proactive measures, to lift the burdens limiting their participation.
A data-driven turbulence model for coarse-grained numerical simulations of two-dimensional Rayleigh–Bénard convection is proposed. The model starts from high-fidelity data and is based on adjusting the Fourier coefficients of the numerical solution, with the aim of accurately reproducing the kinetic energy spectra as seen in the high-fidelity reference findings. No assumptions about the underlying partial differential equation or numerical discretization are used in the formulation of the model. We also develop a constraint on the heat flux to guarantee accurate Nusselt number estimates on coarse computational grids and high Rayleigh numbers. Model performance is assessed in coarse numerical simulations at $Ra=10^{10}$. We focus on key features including kinetic energy spectra, wall-normal flow statistics and global flow statistics. The method of data-driven modelling of flow dynamics is found to reproduce the reference kinetic energy spectra well across all scales and yields good results for flow statistics and average heat transfer, leading to computationally cheap surrogate models. Large-scale forcing extracted from the high-fidelity simulation leads to accurate Nusselt number predictions across two decades of Rayleigh numbers, centred around the targeted reference at $Ra=10^{10}$.
To investigate epidermal growth factor, transforming growth factor-α and interleukin-8 production in nasal mucosa irrigated with hypertonic 2.3 per cent solution with algae extracts, in comparison to 0.9 per cent NaCl during the first two weeks after surgery for nasal polyposis, in relation to symptoms and local findings.
Methods
This prospective study included 20 nasal polyposis patients postoperatively irrigated with hypertonic solution and 20 nasal polyposis patients postoperatively irrigated with isotonic solution. We evaluated nasal symptom score, endoscopic score and mediator levels in nasal secretions before and after irrigation.
Results
Following treatment, nasal symptom score and endoscopic score were significantly lower in the hypertonic solution group (p = 0.023; p < 0.001, respectively). The increase in the epidermal growth factor and the decrease in the transforming growth factor-α and interleukin-8 concentration were higher in the hypertonic group (p < 0.001 for all mediators).
Conclusion
Irrigation with a hypertonic solution was found to be more effective than an isotonic solution in nasal mucosa reparation.
This work investigates the effect of surface roughness on cylinder flows in the postcritical regime and reexamines whether the roughness Reynolds number ($Re_{k_s}$) primarily governs the aerodynamic behaviour. It has been motivated by limitations of many previous investigations, containing occasionally contradictory findings. In particular, many past studies were conducted with relatively high blockage ratios and low cylinder aspect ratios. Both of these factors appear to have non-negligible effects on flow behaviour, and particularly fluctuating quantities such as the standard deviation of the lift coefficient. This study employs a 5 % blockage ratio and a span-to-diameter ratio of 10. Cylinders of different relative surface roughness ratios ($k_s/D$), ranging from $1.1\times 10^{-3}$ to $3\times 10^{-3}$, were investigated at Reynolds numbers up to $6.8 \times 10^5$ and $Re_{k_s}$ up to 2200. It is found that the base pressure coefficient, drag coefficient, Strouhal number, spanwise correlation length of lift and the standard deviation of the lift coefficient are well described by $Re_{k_s}$ in postcritical flows. However, roughness does have an effect on the minimum surface pressure coefficient (near separation) that does not collapse with $Re_{k_s}$. The universal Strouhal number proposed by Bearman (Annu. Rev. Fluid Mech., vol. 16, 1984, pp. 195–222) appears to be nearly constant over the range of $Re_{k_s}$ studied, spanning the subcritical through postcritical regimes. Frequencies in the separating shear layers are found to be an order of magnitude lower than the power law predictions for separating shear layers of smooth cylinders.
The main objective measure to assess the health of the Fontan circulation is the pressure measurement of the superior vena cava or pulmonary arteries. We reviewed the literature for benefits of measuring resting pressure in the Fontan circuit and explored whether dynamic measurement by volume loading or exercise has the potential to refine this diagnostic tool.
Methods:
PubMed was searched for articles showing a relationship between resting post-operative central venous pressure or pulmonary artery pressure and Fontan failure. Relationships between post-operative central venous pressure or pulmonary artery pressure and volume loading changes, such as during exercise or volume loading during cardiac catheterization, were also queried.
Results:
A total of 44 articles mentioned relationships between resting central venous pressure or pulmonary artery pressure and Fontan failure. Only 26 included an analysis between the variables and only seven of those articles found pressure to be predictive of Fontan failure. Ten articles examined the relationship between exercise or volume loading and outcomes and demonstrated a large individual variation of pressures under these dynamic conditions.
Conclusions:
Based on current literature, there is not a lot of strong evidence to show that elevated resting central venous pressure or pulmonary artery pressure is predictive of Fontan failure. Some individuals experience dramatic increases in central venous pressure or pulmonary artery pressure under increased loading conditions with exercise or bolus fluid infusion, while others experience increases closer to that of a healthy control population. Further studies are needed to examine whether more dynamic and continuous monitoring of systemic venous pressures might better predict outcomes in patients with Fontan circulation.
While sin-based responses to divine hiddenness arguments are a road less travelled, they do nonetheless have a number of defenders in the contemporary divine hiddenness literature. I begin this article by exploring the various strategies that have been employed to attempt to motivate such accounts. What none of these strategies seem to take into account, however, is a cluster of facts about the correlation (or lack thereof) between a person's propositional attitudes about God and the degree to which that person displays the relevant moral and intellectual virtues. This article aims to fill this lacuna by mapping out the options available to defenders of sin-based responses in trying to cope with this cluster of facts. I argue that there may be resources available for preserving some aspects of the sin-based approach, but that taking stock of the aforementioned facts will ultimately require the positing of causal factors besides sin in order to generate a sufficient explanation of the phenomenon of non-belief.
Scholars studying the electoral breakthroughs of right-wing illiberalism have arrived at two general conclusions: while they largely rejected the hypothesis that this phenomenon is grounded in voters’ attitudinal shift, they have shown that those voting for the illiberal Right have distinguishing socio-economic and attitudinal characteristics. My analysis reconciles these two sets of findings by documenting the gradual emergence and transformation of the right-wing electorate in Poland in the period 1993–2018 and points to the consolidation of a right-wing partisanship as an organizing factor of the “illiberal moment.” Using the POLPAN panel dataset I find that populist and authoritarian attitudes indeed emerge in Poland in the twenty-first century to distinguish those supporting the Right more and more centered around the PiS party. These attitudes, however, have been incorporated in the context of partisan rivalry—right-wing voters, for example, are more supportive of limiting democratic procedures but only when the Right is in power. In the first decade of the twenty-first century PiS also politicized the lack of partisan consensus on the expansion of the welfare state. PiS incorporated this demand in its stance legitimizing the expansion of the welfare state through what was available in its ideological repertoire: national solidarity, national victimhood, and the idea of a sovereign nation-state joined under the umbrella of Catholic symbolism. This post-consensus polarization and asymmetrical political radicalization resembles the “illiberal moment” in Western Europe that followed the convergence between center-left and center-right parties but they lack a crystallized class-based political identity and social-democratic understanding of political economy to build on.
A spread-out lattice animal is a finite connected set of edges in $\{\{x,y\}\subset \mathbb{Z}^d\;:\;0\lt \|x-y\|\le L\}$. A lattice tree is a lattice animal with no loops. The best estimate on the critical point $p_{\textrm{c}}$ so far was achieved by Penrose (J. Stat. Phys. 77, 3–15, 1994) : $p_{\textrm{c}}=1/e+O(L^{-2d/7}\log L)$ for both models for all $d\ge 1$. In this paper, we show that $p_{\textrm{c}}=1/e+CL^{-d}+O(L^{-d-1})$ for all $d\gt 8$, where the model-dependent constant $C$ has the random-walk representation
where $U^{*n}$ is the $n$-fold convolution of the uniform distribution on the $d$-dimensional ball $\{x\in{\mathbb R}^d\;: \|x\|\le 1\}$. The proof is based on a novel use of the lace expansion for the 2-point function and detailed analysis of the 1-point function at a certain value of $p$ that is designed to make the analysis extremely simple.
Dietary guidelines are increasingly promoting mostly plant-based diets, limits on red meat consumption, and plant-based sources of protein for health and environmental reasons. It is unclear how the resulting food substitutions associate with insulin resistance, a risk factor for type 2 diabetes. We modelled the replacement of red and processed meat with plant-based alternatives and the estimated effect on insulin sensitivity. We included 783 participants (55 % female) from the Childhood Determinants of Adult Health study, a population-based cohort of Australians. In adulthood, diet was assessed at three time points using FFQ: 2004–2006, 2009–2011 and 2017–2019. We calculated the average daily intake of each food group in standard serves. Insulin sensitivity was estimated from fasting glucose and insulin concentrations in 2017–2019 (aged 39–49 years) using homoeostasis model assessment. Replacing red meat with a combination of plant-based alternatives was associated with higher insulin sensitivity (β = 10·5 percentage points, 95 % CI (4·1, 17·4)). Adjustment for waist circumference attenuated this association by 61·7 %. Replacing red meat with either legumes, nuts/seeds or wholegrains was likewise associated with higher insulin sensitivity. Point estimates were similar but less precise when replacing processed meat with plant-based alternatives. Our modelling suggests that regularly replacing red meat, and possibly processed meat, with plant-based alternatives may associate with higher insulin sensitivity. Further, abdominal adiposity may be an important mediator in this relationship. Our findings support advice to prioritise plant-based sources of protein at the expense of red meat consumption.
This article traces the history of the use and reception of field recordings on radio, in France and Britain, outside the categories considered as art or music such as hörspiel or musique concrète. It shows that radio producers had diverse reactions to the use of sonic ambiences recorded in the field. There was an opposition between a ‘Pure Sound School’, which promoted the use of field recordings instead of voice to depict the environment where the reporter was, and a school that privileged voice. If the use of recordings of sonic ambiences was not new, their utilisation on radio as elements autonomous in themselves was. They were falling between categories: they were not reports (because of the absence of voice), they were not musique concrète (because sounds were not modified and were presented within their context, that is, not as sound objects), they were not sound effects (because they lasted several minutes and could be composed through editing), and they were not wildlife recordings (because wildlife could be absent). Sonic ambiences were new sonic objects that took time to digest. This time also represented a listening mutation, and this will be analysed through the beginnings of radio documentaries and the works of sound hunters.
Ezekiel 16 paints one of the harshest pictures in the Hebrew Bible. In a brokenhearted cry of rage, the prophet contemplates Jerusalem's history of relationship with God. Employing familial imagery, the relationship is characterised by constraints and penalties, including instances of sexual violence imposed by God. Consequently, the allegory challenges the perception of the deity as an exemplary figure. This article posits that the allegory deliberately delivers a jolt to its recipients by depicting God as transgressing a social taboo, by altering his role for the people from a father to a spouse. This depiction of incestuous relationship wields the power to evoke threat and terror. It acknowledges that the breaching of the taboo of a father–daughter incestuous relationship, albeit inadvisable, is possible. By ascribing to God a behaviour that fathers strive to avoid, the reproach captures the imagination of its recipients, leaving a profound impact upon them.
Suppose that people seek confidentiality in what would otherwise be a public process—such as litigating or applying for a firearms license—because they are afraid that publicly identifying them will stigmatize them in their (or their families’) religious communities. Should the law allow them to proceed anonymously to better protect their interests and to avoid discouraging their lawsuits or applications? Or would that unduly stigmatize the religious community by branding it as improperly censorious or judgmental—or interfere with religious community members’ ability to evaluate for themselves how their coreligionists are using the courts and other government processes?
Individuals with pre-clinical mobility limitation (PCML) are at a high risk of future functional loss and progression to disability. The purpose of this scoping review was to provide a comprehensive understanding of PCML intervention studies in middle-aged and older adults. We present the interventions that have been tested or planned, describe how they have been conducted and reported, identify the knowledge gaps in current literature, and make recommendations about future research directions. An initial search of 2,291 articles resulted in 14 articles that met criteria for inclusion. Findings reveal that: (1) there is limited published work on PCML interventions, especially in middle-aged populations; and (2) the complexity and variety of PCML measures make it difficult to compare findings across PCML studies. Despite the diversity of measures, this review provides preliminary evidence that rehabilitation interventions on PCML help to delay or prevent disability progression.