This article examines the legal framework for offshore CO2 sequestration in South Korea, paying particular attention to how to ensure the protection of the marine environment from CO2 sequestration in sub-seabed geological formations. It analyses the relevant international regulatory framework, including the 1982 United Nations Convention on the Law of the Sea, the 1972 London Convention and the 1996 London Protocol. It then examines the Korean national legal framework relating to offshore CO2 sequestration. In the absence of detailed regulations on the process of CO2 sequestration in sub-seabed geological formations in South Korea, the article suggests detailed regulations regarding site selection, assessment of potential risks, monitoring and long-term liability to ensure environmental safety and security from offshore CO2 sequestration, which should comply with the 1996 Protocol and relevant guidelines. The development of detailed Korean national regulations ensuring compliance with international rules and standards could serve as best practices driving offshore CCS in the Asia-Pacific region.