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Cancer diagnosis and treatment can result in a significant psychological burden. This study sought to investigate the prevalence of major depression, associated treatments, and suicidal ideation in cancer survivors compared to a non-cancer cohort.
Methods
This is a retrospective, population-based study using survey responses from the National Survey on Drug Use and Health collected from January 2015 to December 2019. Survey data sets were queried for all respondents who provided a cancer history. Respondents with a reported history of cancer (“cancer survivors”) were further stratified by whether they reported a “recent” cancer diagnosis within the past 12 months. Survey responses were evaluated for recent diagnoses of and treatments for major depressive disorder and suicidal ideation.
Results
Among the 212,411 survey respondents identified, 7,635 (3.6%) reported a cancer history, with 1,486 (0.7%) reporting a recent cancer history. There were no differences in prevalence of major depression between cancer survivors and participants without cancer (9.3% vs 9.2%, p = 0.762), though the prevalence was slightly higher among recent cancer survivors (10.0% vs 9.2%, p = 0.259). Among respondents diagnosed with major depression, cancer survivors were significantly more likely to receive treatment for depression (78.6% vs 60.3%, p < 0.001). Suicidal ideation was significantly lower among cancer survivors (5.1% vs 6.2%, p < 0.001) including recent survivors (5.0% vs 6.2%, p < 0.001).
Significance of results
There was no overall difference in the prevalence of major depression between cancer survivors and respondents without cancer. Survivors with major depression were more likely to receive treatments. Prevalence of major depression was higher in recent cancer survivors.
The goal of the Patient-Centered Outcomes Research Partnership was to prepare health care professionals and researchers to conduct patient-centered outcomes and comparative effectiveness research (CER). Substantial evidence gaps, heterogeneous health care systems, and decision-making challenges in the USA underscore the need for evidence-based strategies.
Methods:
We engaged five community-based health care organizations that serve diverse and underrepresented patient populations from Hawai’i to Minnesota. Each partner nominated two in-house scholars to participate in the 2-year program. The program focused on seven competencies pertinent to patient-centered outcomes and CER. It combined in-person and experiential learning with asynchronous, online education, and created adaptive, pragmatic learning opportunities and a Summer Institute. Metrics included the Clinical Research Appraisal Inventory (CRAI), a tool designed to assess research self-efficacy and clinical research skills across 10 domains.
Results:
We trained 31 scholars in 3 cohorts. Mean scores in nine domains of the CRAI improved; greater improvement was observed from the beginning to the midpoint than from the midpoint to conclusion of the program. Across all three cohorts, mean scores on 52 items (100%) increased (p ≤ 0.01), and 91% of scholars reported the program improved their skills moderately/significantly. Satisfaction with the program was high (91%).
Conclusions:
Investigators that conduct patient-centered outcomes and CER must know how to collaborate with regional health care systems to identify priorities; pose questions; design, conduct, and disseminate observational and experimental research; and transform knowledge into practical clinical applications. Training programs such as ours can facilitate such collaborations.
Higher consumption of ‘ultra-processed’ (UP) foods has been linked to adverse health outcomes. The present paper aims to characterise percentage energy from UP foods by participant socio-economic status (SES), diet quality, self-reported food expenditure and energy-adjusted diet cost. Participants in the population-based Seattle Obesity Study III (n 755) conducted in WA in 2016–2017 completed socio-demographic and food expenditure surveys and the FFQ. Education and residential property values were measures of SES. Retail prices of FFQ component foods (n 378) were used to estimate individual-level diet cost. Healthy Eating Index (HEI-2015) and Nutrient Rich Food Index 9.3 (NRF9.3) were measures of diet quality. UP foods were identified following NOVA classification. Multivariable linear regressions were used to test associations between UP foods energy, socio-demographics, two estimates of food spending and diet quality measures. Higher percentage energy from UP foods was associated with higher energy density, lower HEI-2015 and NRF9.3 scores. The bottom decile of diet cost ($216·4/month) was associated with 67·5 % energy from UP foods; the top decile ($369·9/month) was associated with only 48·7 % energy from UP foods. Percentage energy from UP foods was inversely linked to lower food expenditures and diet cost. In multivariate analysis, percentage energy from UP foods was predicted by lower food expenditures, diet cost and education, adjusting for covariates. Percentage energy from UP foods was linked to lower food spending and lower SES. Efforts to reduce UP foods consumption, an increasingly common policy measure, need to take affordability, food expenditures and diet costs into account.
The purpose of this review is to provide a detailed and updated description of the FinnTwin16 (FT16) study and its future directions. The Finnish Twin Cohort comprises three different cohorts: the Older Twin Cohort established in the 1970s and the FinnTwin12 and FT16 initiated in the 1990s. FT16 was initiated in 1991 to identify the genetic and environmental precursors of alcoholism, but later the scope of the project expanded to studying the determinants of various health-related behaviors and diseases in different stages of life. The main areas addressed are alcohol use and its consequences, smoking, physical activity, overall physical health, eating behaviors and eating disorders, weight development, obesity, life satisfaction and personality. To date, five waves of data collection have been completed and the sixth is now planned. Data from the FT16 cohort have contributed to several hundred studies and many substudies, with more detailed phenotyping and collection of omics data completed or underway. FT16 has also contributed to many national and international collaborations.
Social disability is a hallmark of severe mental illness yet individual differences and factors predicting outcome are largely unknown.
Aim
To explore trajectories and predictors of social recovery following a first episode of psychosis (FEP).
Method
A sample of 764 individuals with FEP were assessed on entry into early intervention in psychosis (EIP) services and followed up over 12 months. Social recovery profiles were examined using latent class growth analysis.
Results
Three types of social recovery profile were identified: Low Stable (66%), Moderate-Increasing (27%), and High-Decreasing (7%). Poor social recovery was predicted by male gender, ethnic minority status, younger age at onset of psychosis, increased negative symptoms, and poor premorbid adjustment.
Conclusions
Social disability is prevalent in FEP, although distinct recovery profiles are evident. Where social disability is present on entry into EIP services it can remain stable, highlighting a need for targeted intervention.
In the seventeenth century, the concept of creativity was far removed from most of the fundamental ideas about the creative act - notions of human imagination, inspiration, originality and genius - that developed in the eighteenthand nineteenth centuries. Instead, in this period, students learned their crafts by copying and imitating past masters and did not consciously seek to break away from tradition. Most new material was made on the instructions of apatron and had to conform to external expectations; and basic tenets that we tend to take for granted-such as the primacy and individuality of the author-were apparently considered irrelevant in some contexts. This aim of this interdisciplinary collection of essays is to explore what it meant to create buildings and works of art, music and literature in seventeenth-century England and to investigate the processes by which such creations came into existence. Through a series of specific case studies, the book highlights a wide range of ideas, beliefs and approaches to creativity that existed in seventeenth-century England and places them in the context of the prevailing intellectual, social and cultural trends of the period. In so doing, it draws into focus the profound changes that were emerging in the understanding of human creativity in early modern society - transformations that would eventually lead to the development of a more recognisably modern conception of the notion of creativity. The contributors work in and across the fields of literary studies, history, musicology, history of art and history of architecture, and their work collectively explores many of the most fundamental questions about creativity posed by the early modern English 'creative arts'. REBECCA HERISSONE is Head of Music and Senior Lecturer in Musicology at the University of Manchester. ALAN HOWARD is Lecturer in Music at the University of East Anglia.
Edited by
Rebecca Herissone, Head of Music and Senior Lecturer in Musicology at the University of Manchester,Alan Howard, Lecturer in Music at the University of East Anglia
Edited by
Rebecca Herissone, Head of Music and Senior Lecturer in Musicology at the University of Manchester,Alan Howard, Lecturer in Music at the University of East Anglia
Edited by
Rebecca Herissone, Head of Music and Senior Lecturer in Musicology at the University of Manchester,Alan Howard, Lecturer in Music at the University of East Anglia
When a Master doth a thing a second time, lightly it is for the better.
George Gage to Sir Dudley Carleton, 1 November 1617
This chapter will probe early modern notions of creativity by considering the artistic activities, in and for England, of the most sought-after painter in seventeenth-century Europe – Peter Paul Rubens. The artist's busy workshop helped to satisfy the demand for his works, and as a result Rubens's English patrons, ranging from various dignitaries to Charles I himself, were the recipients of paintings with varying degrees of the master's own participation. An inquiry into Rubens's practice of delegating to studio assistants, and into the value placed by him and his British viewers on autography, will elucidate attitudes towards the manual aspects of creation. A related area of investigation will focus on the phenomenon of self-repetition in the artist's works for his English clients, some of which works were replicas of earlier compositions or reused motifs from previous inventions. Finally, a broader exploration of responses to self-replication, extending at times beyond the shores of England or the confines of painting, will bring to the fore the tensions inherent in early modern attitudes to art.
Replicas and Studio Hands
Although Rubens's stay in England as a diplomatic envoy dates to 1629–30, his relationship with English patrons had begun some thirteen years earlier when Sir Dudley Carleton, the English Ambassador to The Hague, had sought to trade a diamond chain for a hunt scene by the artist.
Edited by
Rebecca Herissone, Head of Music and Senior Lecturer in Musicology at the University of Manchester,Alan Howard, Lecturer in Music at the University of East Anglia
Edited by
Rebecca Herissone, Head of Music and Senior Lecturer in Musicology at the University of Manchester,Alan Howard, Lecturer in Music at the University of East Anglia
This book has its origins in an interdisciplinary conference of the same name, held at the University of Manchester in September 2008 as part of a four-year research project entitled ‘Musical Creativity in Restoration England’, which was funded by the Arts and Humanities Research Council in the UK. The conference brought together a group of seventeenth-century specialists including those working in cultural studies, print culture, the history of ideas, and of course historians of art, architecture, theatre, literature and music, to explore how we can seek to understand what it meant to be creative in the early modern period in England. Te symposium revealed the wide variety of approaches to studying creativity being taken by scholars and research students across the humanities, and led to exciting and fruitful cross-fertilization of ideas between its participants, resulting in discussions that in some cases have led to long-lasting research collaborations.
Tis book presents a selection of twelve essays that were developed from the twenty papers given at the conference. In selecting this group, the editors have sought to include a representative sample of the research that was presented, while also aiming to ensure that the collection is accessible to a genuinely interdisciplinary readership. While music examples are used in some of the chapters, these are kept to a minimum, and are supported by audio samples available at www.alc.manchester. ac.uk/subjects/music/research/projects/musicalcreativity.
from
Mapping Knowledge: The Visual Representation of Ideas
Edited by
Rebecca Herissone, Head of Music and Senior Lecturer in Musicology at the University of Manchester,Alan Howard, Lecturer in Music at the University of East Anglia
This essay grows from a concern with the old art-historical problem of how the perception of art, or in this case more specifically architecture, changes over time. It sets out to explore how verbal representations preserve clues about such changes in the way we see the world, while proposing that the dialogue between subject and object is perhaps more palpable in texts than it is in pictures. The protagonist is seventeenth-century diarist John Evelyn, who travelled in Italy between 1644 and 1646. The account of this journey forms part of his seminal Diary, which he compiled mainly retrospectively from the 1660s onwards. One of the main seventeenth-century English sources for historians of all fields and by some even regarded as having changed travel writing, Evelyn is nevertheless well known for having copied generous parts of his text from earlier guidebooks.2 In the following I will try to dismantle sentence by sentence one short passage in which he describes the city of Genoa. Comparing his text to other seventeenth-century guidebooks allows us to see not only what Evelyn copied, but also what he altered, what he added, and, more importantly, what these alterations and additions tell us about contemporary modes of perception and representation. The ensuing analysis raises questions about concepts of creativity and originality in the period while probing the ordering of vision and knowledge in the seventeenth century.
Edited by
Rebecca Herissone, Head of Music and Senior Lecturer in Musicology at the University of Manchester,Alan Howard, Lecturer in Music at the University of East Anglia
from
Mapping Knowledge: The Visual Representation of Ideas
Edited by
Rebecca Herissone, Head of Music and Senior Lecturer in Musicology at the University of Manchester,Alan Howard, Lecturer in Music at the University of East Anglia
Creation: a making or forming of something, as it were, out of nothing Edward Phillips, The New World of Words
Edward Phillips's attempt to define creation in 1671 highlights a number of issues that are central to developments in thinking about creativity, knowledge and artistic innovation during the seventeenth century. His idea of creating ‘something’ from ‘nothing’ implies, at one level, absolute novelty: a lack of precedence, a complete rupture with and effacement of a past state or experience; something appears where once there was emptiness or blankness. Simultaneously, however, the emphasis on ‘making’ and especially ‘forming’ suggests that there are materials to be moulded: existing matter to be reshaped into something new; Phillips suggests that creation has to be made from something, even as this ‘some-thing’ is described as ‘no-thing’. This ambivalence – the ‘as it were’ in the definition – hints at the multiple concepts and interpretations of creativity that existed in the seventeenth century.
In the early modern period – particularly in the realm of epistemology – creation was understood both in terms of reshaping, translating and reconfiguring that which exists and as the production of fresh entities ‘out of nothing’. Seventeenth-century theories of creativity seem to emanate from precisely this tension between novelty and precedent, between the purity of the new and the foundation of the old.
Edited by
Rebecca Herissone, Head of Music and Senior Lecturer in Musicology at the University of Manchester,Alan Howard, Lecturer in Music at the University of East Anglia
Edited by
Rebecca Herissone, Head of Music and Senior Lecturer in Musicology at the University of Manchester,Alan Howard, Lecturer in Music at the University of East Anglia
Edited by
Rebecca Herissone, Head of Music and Senior Lecturer in Musicology at the University of Manchester,Alan Howard, Lecturer in Music at the University of East Anglia
Edited by
Rebecca Herissone, Head of Music and Senior Lecturer in Musicology at the University of Manchester,Alan Howard, Lecturer in Music at the University of East Anglia
Edited by
Rebecca Herissone, Head of Music and Senior Lecturer in Musicology at the University of Manchester,Alan Howard, Lecturer in Music at the University of East Anglia