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We present numerical as well as experimental results of axisymmetric, axially propagating vortices appearing in counter-rotating Taylor–Couette flow below the centrifugal instability threshold of circular Couette flow without additional externally imposed forces. These propagating vortices are periodically generated by the shear flow near the Ekman cells that are induced by the non-rotating end walls. These axisymmetric vortices propagate into the bulk towards mid-height, where they get annihilated by rotating, non-propagating defects. These propagating structures appear via a supercritical Hopf bifurcation from axisymmetric, steady vortices, which have been discovered recently in centrifugally stable counter-rotating Taylor–Couette flow (Abshagen et al., Phys. Fluids, vol. 22, 2010, 021702). In the nonlinear regime of the Hopf bifurcation, contributions of non-axisymmetric modes also appear.
We report results of a combined numerical and experimental study on axisymmetric and non-axisymmetric flow states in a finite-length, co-rotating Taylor–Couette system in the Taylor vortex regime but also in the Rayleigh stable regime for moderate Reynolds numbers (${\leq }1000$). We found the dominant boundary-driven axisymmetric circulation to play a crucial role in the mode selection and the bifurcation behaviour in this flow. A sequence of partially hysteretic transitions to other axisymmetric multi-cell flow states is observed. Furthermore, we observed spiral states bifurcating via a supercritical Hopf bifurcation out of these multi-cell states which strongly determine the shape of the spiral. Finally, an excellent agreement between experimental and numerical results of the full Navier–Stokes equations is found.
Rift Valley fever virus (RVFV) is a mosquito-transmitted bunyavirus (genus Phlebovirus) associated with severe disease in livestock and fatal encephalitis or haemorrhagic fever in a proportion of infected humans. Although live attenuated and inactivated vaccines have been used in livestock, and on a limited scale in humans, there is a need for improved anti-RVFV vaccines. Towards this goal, Sindbis virus replicon vectors expressing the RVFV Gn and Gc glycoproteins, as well as the non-structural nsM protein, were constructed and evaluated for their ability to induce protective immune responses against RVFV. These replicon vectors were shown to produce the RVFV glycoproteins to high levels in vitro and to induce systemic anti-RVFV antibody responses in immunized mice, as determined by RVFV-specific ELISA, fluorescent antibody tests, and demonstration of a neutralizing antibody response. Replicon vaccination also provided 100% protection against lethal RVFV challenge by either the intraperitoneal or intranasal route. Furthermore, preliminary results indicate that the replicon vectors elicit RVFV-specific neutralizing antibody responses in vaccinated sheep. These results suggest that alphavirus-based replicon vectors can induce protective immunity against RVFV, and that this approach merits further investigation into its potential utility as a RVFV vaccine.
In Taylor–Couette systems, waves, e.g. spirals and wavy vortex flow, typically rotate in the same direction as the azimuthal mean flow of the basic flow which is mainly determined by the rotation of the inner cylinder. In a combined experimental and numerical study we analysed a rotating wave of a one-vortex state in small-aspect-ratio Taylor–Couette flow which propagates either progradely or retrogradely in the inertial (laboratory) frame, i.e. in the same or opposite direction as the inner cylinder. The direction reversal from prograde to retrograde can occur at a distinct parameter value where the propagation speed vanishes. Owing to small imperfections of the rotational invariance, the curves of vanishing rotation speed can broaden to ribbons caused by coupling between the end plates and the rotating wave. The bifurcation event underlying the direction reversal is of higher codimension and is unfolded experimentally by three control parameters, i.e. the Reynolds number, the aspect ratio, and the rotation rate of the end plates.
Reaction time (RT) variability is one of the strongest findings to emerge in cognitive-experimental research of attention deficit hyperactivity disorder (ADHD). We set out to confirm the association between ADHD and slow and variable RTs and investigate the degree to which RT performance improves under fast event rate and incentives. Using a group familial correlation approach, we tested the hypothesis that there are shared familial effects on RT performance and ADHD.
Method
A total of 144 ADHD combined-type probands, 125 siblings of the ADHD probands and 60 control participants, ages 6–18, performed a four-choice RT task with baseline and fast-incentive conditions.
Results
ADHD was associated with slow and variable RTs, and with greater improvement in speed and RT variability from baseline to fast-incentive condition. RT performance showed shared familial influences with ADHD. Under the assumption that the familial effects represent genetic influences, the proportion of the phenotypic correlation due to shared familial influences was estimated as 60–70%.
Conclusions
The data are inconsistent with models that consider RT variability as reflecting a stable cognitive deficit in ADHD, but instead emphasize the extent to which energetic or motivational factors can have a greater effect on RT performance in ADHD. The findings support the role of RT variability as an endophenotype mediating the link between genes and ADHD.
Cal 87 was observed with with XMM-Newton in April of 2003. The source shows a rich emission spectrum, where lines can be identified if they are red-shifted by 700-1200 km s –1. These lines seem to have been emitted in a wind from the system. The eclipse is observed to be shifted in phase by 0.03 ϕorb, where ϕorb is the phase of the optical light curve.
Low concentration of toxic radioactive metals in environmental samples often limits the interpretation of results of infrared studies investigating the interaction processes between the metal ions and environmental compartments. For the first time, we could show that photothermal infrared spectroscopy performed with a pulsed free electron laser can provide reliable infrared spectra throughout a distinct spectral range of interest. In this model investigation, we provide vibrational absorption spectra of a rare earth metal salt dissolved in a KBr matrix and a natural calcite sample obtained by photothermal beam deflection (PTBD) technique and FT-IR spectroscopy, respectively. General agreement was found between all spectra of the different recording techniques. Spectral deviations were observed with samples containing low concentration of the rare earth metal salt indicating a lower detection limit of the photothermal method as compared to conventional FT-IR spectroscopy.
Results of high-energy synchrotron radiation experiments are presented demonstrating the advantages of the high-resolution atomic Pair Distribution Function technique in determining the structure of materials with intrinsic disorder.
Since the discovery of fading X-rays from Gamma-Ray Bursts (GRBs) with BeppoSAX (Piro et al. 1997, Costa et al. 1997), world-wide follow-up observations in optical band have achieved the fruitful results. The case of GRB 970228, there was an optical transient, coincides with the BeppoSAX position and faded (Paradijs et al. 1997, Sahu et al. 1997). These optical observations also confirmed the extended component, which was associated with the optical transient. The new transient are fading with a power-law function in time and the later observation of HST confirmed the extended emission is stable (Fruchter et al. 1997). This extended object seems to be a distant galaxy and strongly suggests to be the host.
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