Mickwitziids are a unique group of brachiopods, known exclusively from the Lower Cambrian. Herein are described the new species Mickwitzia lochmana and M. multipunctata; both species are from southwestern North America. Mickwitzia muralensis Walcott, 1913, the largest mickwitziid, is reported here for the first time from the United States. This paper also discusses the distribution of mickwitziids, their shell structure, and the possible functions of mickwitziid punctae.