We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Emerging wildlife pathogens often display geographic variability due to landscape heterogeneity. Modeling approaches capable of learning complex, non-linear spatial dynamics of diseases are needed to rigorously assess and mitigate the effects of pathogens on wildlife health and biodiversity. We propose a novel machine learning (ML)-guided approach that leverages prior physical knowledge of ecological systems, using partial differential equations. We present our approach, taking advantage of the universal function approximation property of neural networks for flexible representation of the underlying dynamics of the geographic spread and growth of wildlife diseases. We demonstrate the benefits of our approach by comparing its forecasting power with commonly used methods and highlighting the obtained insights on disease dynamics. Additionally, we show the theoretical guarantees for the approximation error of our model. We illustrate the implementation of our ML-guided approach using data from white-nose syndrome (WNS) outbreaks in bat populations across the US. WNS is an infectious fungal disease responsible for significant declines in bat populations. Our results on WNS are useful for disease surveillance and bat conservation efforts. Our methods can be broadly used to assess the effects of environmental and anthropogenic drivers impacting wildlife health and biodiversity.
Vaccines have revolutionised the field of medicine, eradicating and controlling many diseases. Recent pandemic vaccine successes have highlighted the accelerated pace of vaccine development and deployment. Leveraging this momentum, attention has shifted to cancer vaccines and personalised cancer vaccines, aimed at targeting individual tumour-specific abnormalities. The UK, now regarded for its vaccine capabilities, is an ideal nation for pioneering cancer vaccine trials. This article convened experts to share insights and approaches to navigate the challenges of cancer vaccine development with personalised or precision cancer vaccines, as well as fixed vaccines. Emphasising partnership and proactive strategies, this article outlines the ambition to harness national and local system capabilities in the UK; to work in collaboration with potential pharmaceutic partners; and to seize the opportunity to deliver the pace for rapid advances in cancer vaccine technology.
A battery of 32 tests was administered to a sample including 144 Air Force Officer Candidates and 139 Air Cadets. The factor analysis, using Thurstone's complete centroid method and Zimmerman's graphic method of orthogonal rotations, revealed 12 interpretable factors. The non-reasoning factors were interpreted as verbal comprehension, numerical facility, perceptual speed, visualization, and spatial orientation. The factors derived from reasoning tests were identified as general reasoning, logical reasoning, education of perceptual relations, education of conceptual relations, education of conceptual patterns, education of correlates, and symbol substitution. The logical-reasoning factor corresponds to what has been called deduction, but eduction of correlates is perhaps closer to an ability actually to make deductions. The area called induction appears to resolve into three eduction-of-relations factors. Reasoning factors do not appear always to transcend the type of test material used.
We have experimentally investigated the collisionless shock acceleration of ions via the interaction of a relativistic intensity (3 × 1019 W/cm2), 1.053 µm wavelength laser pulse with an underdense plasma. This plasma is formed through the use of a novel cluster jet design that allows for control of the plasma peak density and front scale length without the use of additional plasma-forming laser pulses. When the front density scale length of the target plasma is less than 60 µm, the laser pulse (1 J, 400 fs) is capable of launching an electrostatic shock wave that accelerates a proton beam. This beam is shown to have a narrow divergence angle of 0.8°, a peak flux of 14 × 106 protons/sr with an ion energy exceeding 440 keV. Particle-in-cell simulations indicate this narrow ion beam is produced by converging shocks generated via filamentation of the laser pulse in high-density (near critical) plasma.
How can one speak and act in ways that overcome entrenched social conflicts? In polarized societies, some insist that the survival of democracy depends on people abiding by rules of civility and mutual respect. Others argue that the political situation is so dire that one's values need to be fought for by any means necessary. Across the political spectrum, people feel like they need to choose between the morality of dialogue and the effectiveness of protest. Beyond Civility in Social Conflict makes an important intervention in this debate. Taking insights from nonviolent direct action, it provides a model for advocacy that is both compassionate and critical. Successful communicators can help their opponents by dismantling the illusions and unjust systems that impede human flourishing and pit people against one another. The final chapter turns specifically to Christian ethics, and what it means to 'love your enemies' by disagreeing with them.
Yellow and knotroot foxtail are two common weed species infesting turfgrass and pastures in the southeastern region of the United States. Yellow and knotroot foxtail share morphological similarities and are frequently misidentified by weed managers, thus leading to confusion in herbicide selection. Greenhouse research was conducted to evaluate the response of yellow and knotroot foxtail to several turfgrass herbicides: pinoxaden (35 and 70 g ai ha−1), sethoxydim (316 and 520 g ai ha−1), thiencarbazone + dicamba + iodosulfuron (230 g ai ha−1), nicosulfuron + rimsulfuron (562.8 g ai ha−1), metribuzin (395 g ha−1), sulfentrazone (330 g ai ha−1), sulfentrazone + imazethapyr (504 g ai ha−1), and imazaquin (550 g ai ha−1). All treatments controlled yellow foxtail >87% with more than 90% reduction of the biomass. By comparison, only sulfentrazone alone controlled knotroot foxtail 90% and completely reduced aboveground biomass. Sethoxydim (520 g ai ha−1), metribuzin, and imazaquin controlled knotroot foxtail >70% at 28 d after application. In a rate response evaluation, nonlinear regression showed that yellow foxtail was approximately 8 times more susceptible to pinoxaden and 2 times more susceptible to sethoxydim than knotroot foxtail based on log (WR50) values, which were 50% reduction in fresh weight. Our research indicates that knotroot foxtail is more difficult to control across a range of herbicides, making differentiation of these two species important before herbicides are applied.
This chapter surveys and critiques the three major viewpoints on the ethics of communication, which I label Civility, Victory, and Open-mindedness. For Civility, activism must be governed by a set of rules for respectful engagement. For Victory, the ends justify the means, and for the sake of one’s political goals, one may need to mislead audiences, dismiss opponents, and use ad hominem attacks. For Open-mindedness, it is violent and immoral to impose one’s views on others. I argue that all three perspectives have serious shortcomings, but that each voice expresses a valuable concern. People want their advocacy to be moral, effective, and nonviolent, but often feel like it is impossible to have all three.
Since the rules of civility are often abandoned for the sake of the goals activists are pursuing, this chapter considers whether these goals – rather than a set of universal rules – might themselves suggest moral constraints. To illustrate this point, I analyze two authors who believe that how one communicates is integrally related to what one actually conveys, and thus morality and effectiveness cannot always be separated. Karlyn Kohrs Campbell argues women must be free to reflect on their own experiences rather than being subjected to authoritative interpretations. Even when done in the name of women’s liberation, telling women how they should feel ironically stifles women’s voices. Thus, a dialogical, consciousness-raising style of communication is integrally related to the pursuit of women’s liberation. Paulo Freire likewise argues that propaganda for the cause of liberation ironically perpetuates oppression. Liberators need to be committed to dialogue because the task of liberation itself demands dialogical engagement.
Normatively speaking, Christianity involves a rejection of “us versus them” ways of thinking and speaking. Christian political advocacy must thereby testify to the reconciliation of all people. It would be ironic, even self-defeating, to advocate for Christian commitments in ways that reify divisions between people or deny opponents’ human dignity. But Christians can still make prophetic and incisive criticisms, take controversial stands, and employ rigorous argumentation. Drawing upon the work of Desmond Tutu and J. Deotis Roberts, I argue that Christian witness always proceeds as “good news.” Good news is not only the content but the form of Christian proclamation. Christian speech disrupts systems of injustice and dehumanizing myths, while simultaneously expressing the truth that every person – even those who are currently oppressors – is a beloved child of God. This conclusion can help Christians engage in political, ethical, and cultural conflicts in ways that are simultaneously more persuasive and more faithful to their convictions.
Campbell and Freire rely on an understanding of symbolic action that is not merely instrumental but expressive. Rather than thinking that “the ends justify the means,” these authors consider which messages are conveyed by the means they use and ask whether these implicit messages are conducive to their ultimate ends. In Chapter 4, I analyze how Søren Kierkegaard uses this reasoning to develop an innovative approach to communication that avoids being co-opted by misleading philosophies. A direct, confrontational approach, Kierkegaard reasoned, only serves to confirm people in their illusions, therefore writers need to create opportunities for readers to examine their own lives. I explain the benefits of criticism that transcends “us versus them” binaries and therefore demands interlocutors re-evaluate their categories.
Martin Luther King Jr. argues that means and ends must be commensurable. If one wants to bring about a more equitable society, one must do so by equitable means. This means-ends principle is reiterated in the writings of Gandhi and King, but it has often been treated as something mysterious. A pragmatic case can be made for it if we pay attention to the dynamics of communication. Gandhi and King argue for an approach to social conflict that combines compassion for the needs of their opponents with a resolute opposition to the injustices these opponents perpetrate. Respect and respectability without challenge and protest will not contribute to the development of a more equitable society. But neither will challenge and protest without respect and respectability. By attending to how nonviolent direct actionists combine these two pressures, I develop an alternative to the dominant perspectives in communication ethics, but one that shares their concerns for morality, effectiveness, and nonviolence.
Most people believe there are rules of civility that ought to govern our discourse in moral and political disagreements. These rules operate like the rules of just-war theory: easy to adhere to in theory, but in practice routinely abandoned by all parties for the sake of winning. Drawing on conflict theory and social psychology, I explain how social conflicts make it possible for people to break their own rules of engagement without recognizing that they are doing so. Indeed, the same public figures who speak of the need for civility and unity are often the ones most willing to resort to uncivil and intentionally divisive speech. In any “us versus them” conflict, the perceived necessity for “us” to prevail over “them” tends to outweigh other ethical considerations. The rules of civility, whatever their merits as an ethical theory, are largely ineffective at constraining immoral practices when the chips are down.
In polarized societies like the contemporary United States, communication seems both necessary and ineffective. We need passionate activism that can build coalitions, encourage cooperation, and challenge the myths that stand in the way of a more just social order. Silence favors those in positions of power; division favors the status quo. If society is to be reformed, let alone transformed, people will need to strengthen the bonds of fellowship that make democracy an effective check on totalitarianism.