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Antimicrobial resistance (AMR) poses a significant global health threat, projected to cause 10 million deaths annually by 2050. Addressing AMR requires a coordinated, multidisciplinary approach encompassing infectious disease (ID) clinicians, pharmacists, microbiologists, infection preventionists, and policymakers. The inaugural AMR Summit, hosted by bioMérieux in collaboration with Tampa General Hospital and the University of South Florida Morsani College of Medicine in November 2024, convened experts from various fields to explore innovative strategies for combating AMR. Key topics discussed included the role of multidisciplinary teams in antimicrobial stewardship programs, advancements in rapid diagnostic tests and antimicrobial susceptibility testing, the application of implementation science in AMR, and the integration of next-generation sequencing in ID diagnostics. The summit underscored the importance of diagnostic innovation, interdisciplinary collaboration, policy, advocacy, and public engagement in advancing efforts against AMR.
We present a novel scheme for rapid quantitative analysis of debris generated during experiments with solid targets following relativistic laser–plasma interaction at high-power laser facilities. Results are supported by standard analysis techniques. Experimental data indicate that predictions by available modelling for non-mass-limited targets are reasonable, with debris of the order of hundreds of μg per shot. We detect for the first time two clearly distinct types of debris emitted from the same interaction. A fraction of the debris is ejected directionally, following the target normal (rear and interaction side). The directional debris ejection towards the interaction side is larger than on the side of the target rear. The second type of debris is characterized by a more spherically uniform ejection, albeit with a small asymmetry that favours ejection towards the target rear side.
Cannabis use and familial vulnerability to psychosis have been associated with social cognition deficits. This study examined the potential relationship between cannabis use and cognitive biases underlying social cognition and functioning in patients with first episode psychosis (FEP), their siblings, and controls.
Methods
We analyzed a sample of 543 participants with FEP, 203 siblings, and 1168 controls from the EU-GEI study using a correlational design. We used logistic regression analyses to examine the influence of clinical group, lifetime cannabis use frequency, and potency of cannabis use on cognitive biases, accounting for demographic and cognitive variables.
Results
FEP patients showed increased odds of facial recognition processing (FRP) deficits (OR = 1.642, CI 1.123–2.402) relative to controls but not of speech illusions (SI) or jumping to conclusions (JTC) bias, with no statistically significant differences relative to siblings. Daily and occasional lifetime cannabis use were associated with decreased odds of SI (OR = 0.605, CI 0.368–0.997 and OR = 0.646, CI 0.457–0.913 respectively) and JTC bias (OR = 0.625, CI 0.422–0.925 and OR = 0.602, CI 0.460–0.787 respectively) compared with lifetime abstinence, but not with FRP deficits, in the whole sample. Within the cannabis user group, low-potency cannabis use was associated with increased odds of SI (OR = 1.829, CI 1.297–2.578, FRP deficits (OR = 1.393, CI 1.031–1.882, and JTC (OR = 1.661, CI 1.271–2.171) relative to high-potency cannabis use, with comparable effects in the three clinical groups.
Conclusions
Our findings suggest increased odds of cognitive biases in FEP patients who have never used cannabis and in low-potency users. Future studies should elucidate this association and its potential implications.
The introductory chapter provides an overview of the book’s focus as a whole and explores its relation to existing historiography, including its engagement with decolonial and postcolonial theory and scholarship in Indigenous Studies and Latin American Studies. In highlighting the book’s unique arguments, contributions, and perspectives, the Introduction explains the concept and double meaning of "troubling encounters" and provides the book’s thematic organization. Noting that some chapters adopt a local perspective, others a national one, and yet others draw attention to transnational and even global domains, the Introduction reflects upon the variety of scales for interpreting and troubling the history of encounters in the human sciences. For the authors, the legacies of those scales are read in the myriad interactions of expedition science, in the relationality implied in fieldwork or the logic of settler colonial custodial institutions, and finally in the resulting theories about human nature and behavior that circulated globally within scientific circles and beyond.
The Preface outlines the origins, motivations, history, and stakes of the project that led to the publication of this book, and it discusses the project’s relationship to scholarship in Indigenous Studies and engagement of key works in that field. It explores what an approach informed by Indigenous Studies can bring to the history of the human sciences, and how it might build upon existing scholarship on this topic.
In this bold reconsideration of the human sciences, an interdisciplinary team employ an expanded theoretical and geographical critical lens centering the notion of the encounter. Drawing insights from Indigenous and Latin American Studies, nine case studies delve into the dynamics of encounters between researchers, intermediaries, and research subjects in imperial and colonial contexts across the Americas and Pacific. Essays explore ethical considerations and knowledge production practices that prevailed in field and expedition science, custodial institutions, and governance debates. They reevaluate how individuals and communities subjected to research projects embraced, critiqued, or subverted them. Often, research subjects expressed their own aspirations, asserted sovereignty or autonomy, and exercised forms of power through interactions or acts of refusal. This book signals the transformative potential of Indigenous Studies and Latin American Studies for shaping future scholarship on the history of the human sciences. This title is also available as Open Access on Cambridge Core.