Beginning with the public controversy over matters of conscience between William Gladstone and John Henry Newman in the nineteenth century, this article explores the significance of ‘conscience’ for moral theology in the Anglican tradition. Noting the genealogy of Newman’s thought and his debt to the eighteenth-century divine, Bishop Butler, the lecture also brings this tradition of thinking into conversation with more recent reflection about conscience in Roman Catholic moral theology. While ‘freedom of conscience’ is often emphasized in contemporary moral reflection, the lecture notes that ‘the obligations of conscience’ are also significant in the thought of Newman and others. The article considers the recent intervention on ‘Episcopacy and Conscience’ by the Faith and Order Commission of the Church of England, before ending with a series of questions about the place of moral formation in seminary education in the Anglican Communion: how might Newman’s thinking about conscience animate our understanding of the spiritual and moral formation offered to ordinands?