Clinical trials are a cornerstone of evaluating new interventions. Although there are similarities between clinical trials across medical specialties there are specific issues that need to be considered when designing, running and evaluating clinical trials in mental health. The purpose of this chapter is to present an overview of the common principles and methods of interventional clinical trials with illustrations drawn from general psychiatry. The chapter provides a guide to understanding clinical trials from design to analysis, drawing on recent work to illustrate fundamental concepts and covers novel factorial and platform designs. outlining advantages and disadvantages of each. This chapter summarises essential steps of interventional clinical trials in psychiatry describing the process from initial hypothesis generation, the role of patient and public involvement, steps to prepare a trial protocol, statistical considerations dissemination of results. The aim is to provide the reader with the tools to be able to understand different methodologies and in design of clinical trial in mental health.

This chapter has been written from the stance of a patient and public contributor to mental health research. It examines the role of patient and public involvement in mental health research which has evolved since the mid 1960s and continues to do so. Examining the people, roles and research and providing a definition for the different stages of Patient and Public Involvement, the chapter looks at how these roles interact, the ethics and rationale for involvement, the power relations between the various parties, whether involvement is moving the research agenda closer to preventative health care, and the subject of equality, diversity and inclusion. The difficulties of working with people with serious mental health issues are addressed. Case studies are given to illustrate various points. Subjects such as training and language are included. The complex subject of evaluation and impact and how they can be resolved are raised. Finally, the chapter concludes by inviting the reader to consider what ‘good PPI’ is, and how it is done.

This chapter explores a range of theoretical and conceptual resources for making sense of the state, with an accent on those most relevant to the role of the state in sustainability transitions. It looks at how the state has been addressed to date in literatures on socio-technical transitions, but also how conceptualisations in disciplines as diverse as politics and political theory, political economy and international relations, geography, sociology and development studies can be selectively combined to provide a more multifaceted, historical, global and political account of the state in all its dimensions as they relate to the challenge of sustainability transitions.

The first chapter of the book covers the context, aims and objectives of the book and situates these aims and the book’s approach in relation to both existing strands of academic scholarship and contemporary policy debates about the role of the state in sustainability transitions.

This chapter examines three reasons for discontent with law’s governance of technology. Reservations concern the exercise of legal powers, the convenience of legal regulations, and prestige. The analysis is supplemented with the impact that the pace of technological innovation has on legal systems and the distinction between internal and external problems of legal governance. The internal problems regard the efficacy, efficiency, and overall soundness of the normative acts; the external problems are related to the claims of further regulatory systems in society, such as the forces of the market, or of social customs. By following the recommendations of Leibniz in the sixth paragraph of his Discourse on Metaphysics, the overall idea is to discuss the simplest possible hypothesis to attain the richest world of phenomena. Discontent with law’s governance of technology is indeed a complex topic with manifold polymorphous ramifications.

The primary motivation of members of the ruling class is the quest for power. Power, which enables people to accomplish other goals, is also a desired end in itself. Those who have the greatest desire for power will self-select into activities that allow them to exercise power over others. Participants in the political marketplace will be most successful if they are open to negotiating any offer from other participants, which implies that principled politicians will be at a disadvantage to those who are less principled. In their quest for power, the ruling class seeks stability to prevent challengers from displacing them. Creative destruction, in markets for goods and services and in the political marketplace, works against the elite, so there is a tendency for the economic and political elite to work together to prevent that creative destruction. Unchecked, this tendency can displace progress with stagnation.

This chapter analyzes voluntary compliance in tax contexts, focusing on the importance of procedural justice and tax morale. It also explores conditions under which governments can achieve optimal revenue levels.

Constructivism emphasizes the role of ideas, identities, and norms in shaping state behavior and international politics, as well as the intersubjective and relational nature of these ideational factors. Social relations “make or construct people – ourselves – into the kinds of beings that we are. Conversely, we make the world what it is, by doing what we do with each other and saying what we say to each other” (Onuf, 1998, 59). Constructivism therefore highlights the intangible yet relational aspects of our reality: a world in which the meaning of objects and actions is not fixed but socially constructed through our interactions; states are held together by collective belief and actively participate in the social construction of anarchy. Norms play a significant role by defining appropriate behavior and enabling action by providing a framework for actors to understand and interact with the world.

This chapter develops a theory to explain why counterrevolutions emerge and succeed. This movement-centric theory emphasizes the strategies movement leaders embrace, which, more than anything else, define the capacities and interests of the old and new regimes during the post-revolutionary transition. All revolutionary governments enjoy an initial power advantage over the old regime. Whether a counterrevolution emerges depends on how much capacity these old regime forces have left and how much their interests are threatened by revolutionary rule. And whether their counterrevolutions succeed depends on how effectively revolutionaries can preserve their initial capacity through the tumultuous transition. Specifically, the chapter lays out a post-revolutionary “governance trilemma,” which requires new leaders to simultaneously manage the concerns of lingering old regime forces, elites in their coalition, and popular groups who supported the revolution. The chapter then explains how these dynamics differ following two ideal-typical forms of revolution: radical-violent movements and moderate-unarmed movements. Counterrevolutions are less likely to emerge following extreme versions of both movements – because the former lowers counterrevolutionary capacities and the latter lowers their interests in restoration. However, counterrevolutions are more likely to succeed against moderate-unarmed movements, because they establish governments that lack key tools for effectively navigating the governance trilemma.

A theoretical intervention into the challenge of thinking through the complexities of life, in Iran or elsewhere. Hannah Arendt and Michel Foucault offer us a model of thinking as a practice. Each attempted one project in which they were thinking systematically about ongoing events, and offering that thinking as a contribution to public understanding. Arendt traveled to Jerusalem to observe the Adolf Eichmann trial, and her contemporaneous writing was published in The New Yorker magazine. Foucault traveled to Iran to observe the early stages of the revolution, and his contemporaneous writing was published (mostly) in the Corriere della Sera newspaper. These two projects have commonly been regarded as their author’s most controversial and have often been ignored or used to denigrate the writer’s entire theoretical oeuvre. Yet they offer compelling models of thinking as a practice that critically links the self and the world. Rescuing theory from the confines of academic specialization restores it, and us, to the possibility of thinking as a practice of freedom, and freedom as the daily possibility of beginning anew.

Chapter 6 examines the Sectarians’ portrait of the end-time destruction of its enemies. The depictions of eschatological violence offer insights into how the Sectarians responded to their present overmatched position while simultaneously affirming their special status. Sectarian texts imagine an imminent end of days that would usher in a period in which all of its enemies – both foreigners and other Jews – would be vanquished in the end-time battle.

This chapter provides general concluding thoughts on the book and insights into larger contributions to the scholarly fields in which it interacts.

This chapter discusses the recent scholarly interest in the history of masculinity in Western society, particularly in early modern Europe, and places the evidence from the Selbstzeugnisse in this context. The texts the men left perform a model of masculinity that emphasizes the men’s power over the market, but also draws on other models of masculinity available in this culture, particularly “patriarchal manhood,” which endows men who successfully found and manage a nuclear household with honorable manhood.

The USA as a prison where Black people are confined inside a barbed wire of stereotypes – an idea memorably articulated by Malcolm X in 1963 – is influentially explored in works by Amiri Baraka, Etheridge Knight, and Reginald Dwayne Betts, a three-man mini-tradition within prison writing. Circumstances leading to Baraka’s experience of solitary confinement (memorably chronicled in his 1979 poem “AM/TRACK”) are the subject of the first third of the chapter. Etheridge Knight, who in prison forged his own poetic path out of tools provided partly by Malcolm and Baraka, is the subject of the next third. The Knight-inspired Reginald Dwayne Betts, a lawyer-poet who was incarcerated as a teenager, is the focus of the rest of the chapter (except for a brief examination of Baraka’s son, Ras, a significant political leader). All four men articulate secrets of survival in the coils of carceral culture and model alternative ways of imagining justice.