We investigated the dual relationship between information and communication technology (ICT) use at work and employee well-being through the framework of the job demands-resources theory. Data were collected from the seventh European Working Conditions Survey (Eurofound), which involved 37 countries and a representative sample of 7,900 workers. The findings revealed that ICT plays a dual role. On one hand, ICT enhances job autonomy, which positively influences work engagement and, subsequently, improves well-being. On the other hand, ICT use increases workload, leading to greater job exhaustion and reduced well-being. Additionally, autonomy was found to be negatively related to exhaustion, offering a secondary positive pathway to well-being. The study also examined the moderator role of employee age. Results showed that age amplifies the negative relationships between ICT use, workload, and well-being. Overall, the study highlights the complex interplay between ICT use at work and employee well-being.