The numbers of robots in organizations grow at an increasing rate. However, very little is known about how robotization (i.e., the implementation of robots at work) affects the work characteristics of the jobs it impacts. This qualitative study focuses on exploring the influence of industrial robots on perceived work characteristics. Eighteen semi-structured interviews were conducted with production line workers and supervisors of four Spanish manufacturing companies. Results showed benefits in physical demands, perceived skill variety, and improved social relationships. We found inconsistent results for job complexity, task variety, and autonomy. Based on our findings, we suggest specific moderators that may be influencing the relationship between robotization and some work characteristics. The findings of our study contribute to the existing literature by expanding work design theory, providing empirical evidence on the influence of an antecedent of work characteristics (robotization), and suggesting several moderators.