In the first half of the twentieth century, hormones took pride of place as life's master molecules and the endocrinologist took precedence over the geneticist as the scientist offering the means to control life. But, as with molecular genetics and biotechnology today, the status of endocrinology was not based solely on contemporary scientific and medical practices. To a high degree it was also reliant on expectations or visions of what endocrinologists would soon be able to do. Inspired by the approach of social studies of techno-scientific expectations, the aim of this article is to explore some of the great expectations connected to the development of endocrinology in the 1930s. The analysis is based on popular books written by the American physician and endocrinologist Louis Berman. The paper argues that Berman thought not only that it was perfectly possible to understand human nature through hormone analysis but that endocrinologists would be able to control, design and ‘improve’ humans by using hormone replacement therapy. Furthermore, in contrast to most of the eugenics of his time, Berman suggested that the whole population of the world should be improved. As a political activist he wanted to contribute to the development of new human beings, ‘ideal normal persons’, thereby reaching an ‘ideal society’. That HRT could involve risks was something that he seems not to have taken into account.

The Isotope School was established in 1951 by the British Atomic Energy Research Establishment (AERE) at Harwell following the model of the American Oak Ridge Institute of Nuclear Studies. Until its dissolution in 1967, it played an important role in the expansion of radioisotope techniques in Britain and Western Europe. This paper traces the origin and activities of the Isotope School, and describes the content of its courses and the composition of its audiences both in Britain and abroad. These illustrate the motivations behind the early diffusion of nuclear technology and the importance of Cold War politics in shaping the flows of materials and expertise. In particular, the ban on attendance of Eastern European students at the courses reveals a persistent tension inside the British nuclear programme: the conflict between the drive for disseminating nucleonics and the restrictions forced by national security concerns.

William Cullen, lecturer in chemistry at Glasgow and Edinburgh Universities, spent many years formulating his own theory of heat and combustion, the most developed version of which appears in a little-known set of lecture notes of 1765. Cullen's theory is of particular interest to historians of chemistry as an example of his ideal of ‘philosophical chemistry’, an autonomous branch of natural philosophy distinct from the mechanical philosophy, with its own general laws and explanations of phenomena justified by observation. The theory assimilated Joseph Black's recent discovery of fixed air as well as Cullen's investigations of the generation of heat in chemical operations. It was formulated just one year before British chemists' sudden identification of new ‘airs’ was dramatically to change the field of phlogiston theory. The theory differs in important ways from any version yet discussed. It successfully brought both heat and elective attraction within its explanatory domain. It set out a causal hierarchy which reversed the usual pattern evinced in earlier sets of lecture notes, subordinating the mechanical to the chemical in the form of Cullen's theory of elective attraction. The paper argues that Cullen was attempting to bring the study of heat as well as combustion within the bounds of his ‘philosophical chemistry’ by means of his single unifying theory.

Baldwin Spencer and F. J. Gillen's Native Tribes of Central Australia (1899) is now remembered as an approximation of the anthropological method that would soon be conventional: a comprehensive study of a delimited area, based on sustained fieldwork, portraying a population's distinctive character. In 1913, however, Bronislaw Malinowski said of Spencer and Gillen's studies that ‘half the total production in anthropological theory ha[d] been based upon their work, and nine-tenths affected or modified by it’. Native Tribes inspired an intense international debate, orchestrated by J. G. Frazer, broker of the book's publication, predicated on the assumption that indigenous Australians were the most primitive of living peoples, whose totemism was somehow at the base of civilization's highest achievements – monogamous marriage and truly spiritual religion. But the debate proved irresolvable in Frazer's terms. Pondering conflicting interpretations of totemism, anthropologists rejected unilinear models of social evolution like Frazer's. Nationally differentiated populations of professional anthropologists emerged in the early twentieth century, developing distinctive theoretical schemes. Nevertheless, some issues central to the debate remained vital. For example, how were magical, scientific and religious modes of thought and action to be distinguished? And in Australia, analyses of indigenes were distinctively construed. White settlers, concerned to legitimate colonial rule, asked specific questions: did Aborigines have established ties to specific lands? Were Aborigines capable of civilization? Biogeographical theory underpinned Spencer's relatively liberal conclusions, which had precursors and successors in Australian anthropology: Aborigines had defined criteria of land ownership, their habits were suitable adaptations to their circumstances, and observed cultural diversity among Aborigines denoted their ‘nascent possibilities of development along many varied lines’.