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The 12-item Body Appreciation Scale-2 for Autistic Adults (BAS-2A; Longhurst et al., 2024) is a contemporary measure of positive body image that captures body appreciation as holding a positive view towards the aesthetic and sensory body and its unique characteristics and needs, resisting harmful societal messages regarding appearance, and caring for the sensory body. The BAS-2A can be administered online or in-person to autistic adults without a co-occurring intellectual/learning disability and is free to use in any setting. This chapter discusses the development of the BAS-2A using community involvement before providing its psychometric evidence. More specifically, the BAS-2A has been found to have a single-factor structure within exploratory and confirmatory factor analyses and is fully invariant across time (i.e., baseline, after 3 weeks), gender identities (i.e., women, men) and autistic status (i.e., formally diagnosed, in the process of receiving a diagnosis). Internal consistency reliability, convergent validity, discriminant validity, and incremental validity support the use of the BAS-2A. Next, this chapter provides the BAS-2A items in their entirety, instructions for administering the BAS-2A to participants, the item response scale, and the scoring procedure. Logistics of use, such as permissions, copyright, and contact information, are provided for readers.
Several neurotransmitter systems play a key role in decision-making. The serotonergic system plays a neuromodulatory role, and is very widely connected, influencing a very wide variety of behaviours including sleep, mood, sexual behaviour, eating and memory. The norodrenergic system has a key connection to the prefrontal cortex, which we know is vital in decision-making. Noradrenaline also has a role in sleep. The dopaminergic system is important for working memory, novelty-seeking and attention. All of these contribute to decision-making.
The Liolopidae (Diplostomoidea) are a small family of digeneans that parasitize reptiles and amphibians as adults. Knowledge of intermediate hosts in this family remains scarce, leaving a major gap in the understanding of liolopid biology. To date, the only fully elucidated life cycle is that of Liolope copulans Cohn 1902, a species infecting Asian salamanders, with no other cercarial or metacercarial stages known. This study aimed to identify potential intermediate hosts for Paraharmotrema karinganiense, found in several chelonian species from southeastern Mozambique and South Africa. African apple snails of the genus Lanistes and Nothobranchius killifish were sampled from temporary pools in Karingani Game Reserve, southern Mozambique. Snails were screened over 9 months for cercarial shedding, and encapsulated metacercariae recovered from the spotted killifish (N. orthonotus, Peters) (Cyprinodontiformes: Nothobranchiidae) were excysted for morphological and molecular analyses. Fork-tailed cercariae from Lanistes sp. and 1 metacercaria found in the spotted killifish were genetically identical to the adult of P. karinganiense. This study provides the second documented life cycle of a liolopid trematode and presents the first life cycle for the family based on natural infections, being the first completely documented life cycle for freshwater trematodes from southern Africa. This linkage of larval and adult specimens signifies the importance of Nothobranchius killifish as intermediate hosts as well providing insight in parasite transmission dynamics within temporary aquatic ecosystems.
Emergency medical care in Pakistan remains uncoordinated due to the absence of a platform to connect hospitals, patients, and ambulances. Consequently, during periods of resource shortage and crowding of the emergency department at hospitals, patients and ambulances are unable to select the best site for patient management or transfer of patients, resulting in suboptimal care and poor outcomes.
Objectives
We developed a digital platform called EMCON (Emergency Connection) application, which can be used for inter-hospital and hospital-to-patient/ambulance communication to coordinate patient care. The platform offers real-time information on resource availability, facilitates interhospital patient transfers, coordinates ambulance responses, and assists patients in making decisions about seeking emergency care.
Implementation
The platform offers real-time information on resource availability, facilitates interhospital patient transfers, coordinates ambulance responses, and assists patients in making decisions about seeking emergency care. It has a range of features that allow hospitals to control the data that they share to maintain hospital buy-in, incorporates both electronic and manual data entry for real-time updates in low-resource settings or during electronic medical record disruption, and provides visual content and appointment scheduling services to keep patients engaged.
Results
The pilot testing of the EMCON platform yielded promising outcomes, highlighting its adaptability and effectiveness in diverse health care settings. Integration with an electronic medical record (EMR)-equipped tertiary hospital demonstrated seamless real-time data updates, ensuring efficient resource management and coordination. Meanwhile, the successful implementation at a resource-reliant blood bank underscored EMCON’s versatility, allowing manual data entry for hospitals without EMR systems. These results emphasize the platform’s practicality and potential to revolutionize emergency health care access in low- and middle-income countries (LMICs). EMCON’s ability to bridge coordination gaps and enhance resource allocation holds great promise for improving patient outcomes, particularly in resource-constrained settings.
Conclusion
EMCON serves as a promising solution to address critical coordination issues in emergency care, bridging the gap between hospitals, patients, and ambulances to improve emergency health care access in low-resource settings.
To evaluate the accessibility and acceptability of implementing a telephone-based psychological support intervention for patients with metastatic cancer in the Indian palliative care settings.
Materials and methods
The present single centered experimental study was conducted on 181 adult metastatic cancer patients who were referred to the pain and palliative medicine department by medical oncologists at a tertiary hospital, India. The patients were purposely assigned to two groups: In Group-A 90, patients received a combination of palliative and psychological support. In Group-B, 91 patients received only structured palliative care. As per the department protocol, patients in each group were followed up on days 0, 7, 14, 21, and 28. Before each session, patients completed questionnaires that are based on disease-related symptoms and psychological well-being.
Results
It was found out that patients with telephone based psychological support integrated with palliative care has shown gradual improvement in physical and psychological symptoms from day 7 to day 28 when compared to the control group with p-value < 0.05. Additionally, 67% of patients continued their follow-up with the psychologist, indicating the accessibility and acceptability of the treatment. Furthermore, 87% of patients preferred voice calls over video calls because of the limited internet access (N = 72%).
Conclusion
Therefore, it can be concluded that the combined approach of pain management through palliative care and continuous telephone based psychological support has contributed to their holistic well-being.
Significance of results
The findings highlight that integrating telephone-based psychological support within palliative care services is both feasible and acceptable for patients with metastatic cancer in India. This approach not only improves physical and psychological outcomes but also enhances the continuity of care, especially in resource-limited settings where in-person psychological services may not always be accessible.
A significant association between tomato consumption and a lower risk of developing hypertension has been reported. In this study, we aimed to investigate the relationship between tomato intake and prehypertension risk among Korean adults. Hypertension was defined according to the criteria established by the Korean Society of Hypertension. The study participants were selected from the Health Examinees cohort study. Tomato consumption was measured using an FFQ and categorised into quintiles based on the amount consumed. Higher tomato consumption was associated with a lower risk of prehypertension in men (hazard ratio (HR) 0·86, 95 % CI 0·80, 0·92, Pfor trend 0·0005). Women in the highest quintile also showed a similar trend (HR 0·94, 95 % CI 0·90, 0·99, Pfor trend 0·0091). Stratified analyses revealed a reduced risk of prehypertension across all subgroups, except underweight individuals and those with a history of alcohol consumption (all Pfor interaction < 0·05). These findings indicate that higher tomato intake may offer potential advantages for managing blood pressure levels.
Longer life expectancy and growing income inequality have prompted an increasing interest in understanding the impact of ageing on nutritional requirements in order to optimise intakes, increase the number of years lived in good health and reduce morbidity and associated health and social care costs. Food insecurity reduces access to nutritious and healthy food. Understanding the evidence base on the impacts of food insecurity and the maintenance of food security for older people is crucial to informing policy and intervention. The increase in numbers of older people experiencing food insecurity is a public health emergency and is associated with under and malnutrition. Food insecurity can be experienced at any stage of the life course but has been more widely studied with families and children where poverty is a major driver. Food insecurity in later life has been less well explored by academics, but differs from that experienced in earlier years due to additional complexities, as physical and cognitive health amplify the impact of poverty. Additionally, factors which can appear to be relatively small in impact can act in a cumulative way to push people towards food insecurity. This review will draw on research about older people’s food practices, contexts and experiences in relation to food insecurity in later life and offers a model of food insecurity that has the potential to guide focused public health efforts in order to support the older population to be food secure.
To examine the association between snack characteristics (snack frequency, snack energy density and snack nutritional quality) with diet quality and cardiometabolic risks among US adolescents from the 2009–2016 National Health and Nutrition Examination Survey. Cross-sectional dietary data collected using a 24-h dietary recall from the 2011–2016 National Health and Nutrition Examination Survey (1999 boys and 1897 girls aged 12–19 years) were analysed. Associations between snack characteristics with diet quality, fasting blood glucose, TAG, total cholesterol, HDL, LDL, blood pressure, waist circumference and metabolic syndrome risk score using multiple linear regression were analysed stratified by sex. Higher snack nutritional quality (β (95 % CI): boys 0·31 (0·09, 0·52); girls 0·44 (0·30, 0·57)) was linked to better overall diet quality, whereas snack energy density excluding beverages (β (95 % CI): boys –1·82 (–2·52, –1·12); girls –1·75 (–2·69, –0·82)) was linked to poorer overall diet quality. Among girls, higher snack frequency was associated with lower waist circumference and lower fasting blood glucose (–0·67 (–1·28, −0·05)). Additionally, higher snack energy density and nutritional quality were associated with lower waist circumference and TAG, respectively. No associations between snack characteristics and cardiometabolic indicators or metabolic syndrome risk score were observed for boys. Findings suggest that strategies to improve adolescent snack nutritional quality and energy density may enhance overall diet quality. However, limited associations were observed between snack characteristics and cardiometabolic risk indicators among girls only. Prospective studies are needed to further investigate the relationship between snack characteristics and adolescent health outcomes.
We characterized antibiotic prescribing for outpatient telemedicine visits among a large cohort of pediatric, adult, and older adult populations during 2021. Opportunities exist for improving antibiotic prescribing in outpatient telemedicine, especially for respiratory conditions and among rural and older adult populations.
In Canada, the management of migraine is commonly carried out by primary care providers. Guidelines for the acute and preventative management of migraine in Canada are published by the Canadian Headache Society (CHS). There are currently limited data describing prescribing patterns among clinicians caring for patients with migraine in Canada.
Aims:
Our aim for this exploratory study was to characterize the current pharmacological treatments prescribed for patients with migraine in Nova Scotia, Canada, seeking care through their primary care providers.
Methods:
We conducted a retrospective cross-sectional analysis of deidentified electronic medical record (EMR) data collected from January 2019 to December 2023 from the Maritime Research Network for Family Practice (MaRNet-FP) to identify prescribing patterns for the acute and preventative management of migraine in Nova Scotia.
Results:
In total, 3075 active patients who received a diagnosis of migraine were identified in the MaRNet-FP EMR database (6.53% of total patients). Migraine patients were predominantly female (81%) with an average age of 44 ± 16 years. Between 2019 and 2023, 50% of patients with a migraine diagnosis received a prescription for a medication that can be used for the acute management of migraine, most commonly, nonsteroidal anti-inflammatory drugs and triptans. Over the same period, 60.4% of patients were prescribed a medication that can be used for the prevention of migraine, the most common of which were anti-depressants and beta-blockers.
Conclusion:
Our findings demonstrate alignment with CHS guidelines but highlight potential undertreatment of migraine.
Although first performed several years ago, percutaneous total cavopulmonary connection has not yet become a widely adopted procedure in patients with univentricular circulation.
Methods and objectives:
We describe a case involving a novel, modified technique for the percutaneous completion of the Fontan circulation using covered stents in a 12 kg patient.
Results:
The transcatheter Fontan completion was successfully performed. Minimal surgical preparation included banding of the inferior vena cava during the preceding superior cavopulmonary connection. Using needle puncture to create the anastomosis and implanting covered stents, a total cavopulmonary connection with an intra-atrial tunnel was established. The patient recovered uneventfully.
Conclusion:
Percutaneous total cavopulmonary connection is feasible and may represent a less invasive alternative for selected patients. However, data on this approach are currently very limited, and further studies are urgently needed.
Brief, low-intensity interventions may hold untapped promise for bolstering maternal health in low-resource contexts. The current study used propensity score matching (PSM) to evaluate uptake and differential effectiveness of two low-intensity digital perinatal health (PH) support programs in Lima, Peru. Pregnant women (N = 251) were assigned to one of two conditions (PH vs. trauma-focused PH [TF-PH]) and received weekly psychoeducational content via WhatsApp from a lay paraprofessional for 5 weeks. Conditions were not randomly assigned; PSM was used to improve causal inference of the condition. Women were interviewed before participation (T1), immediately following treatment (T2) and at 3 (T3) and 12 months postpartum (T4). Intimate partner violence had strong negative effects on women’s mental health, multisystem resilience and parenting, and single mothers reported higher levels of depression and posttraumatic stress symptoms than did partnered women. Intervention uptake was high, with 77% of women participating in all sessions. There were no significant differences between treatment groups over time, but effect sizes indicated a slight advantage of the TF-PH condition in addressing depression symptoms (dr = −0.29) and multisystem resilience (dr = 0.39). Study findings suggest that brief interventions may be well-received and that trauma-focused supports may also confer additional benefits for addressing depression and resilience.
Just as prospective differentiation between true emergencies and calls for subacute patients is critical to the delivery of prehospital care, retrospective differentiation is critical to research and quality improvement. Determining the acuity of patients based on the type of care they received could complement the vital-sign-based instruments currently popular, yet imperfect. The study aim was to create a consensus definition of time-dependent care and a list of time-dependent interventions in paramedicine.
Methods:
The study was a Delphi approach consisting of four rounds of voting by a bi-provincial panel of 22 Canadian key informants representing medical first responders, paramedics, and physicians – first to agree on a definition of time-dependent care – then to categorize 29 clinical and 34 pharmacological interventions.
Results:
Based on the consensus definition of “A majority of patients who should receive the intervention, according to provincial protocols, would suffer a direct prejudice to their health or safety if the intervention, provided on its own, was not performed within eight minutes of the initial call,” the panel reached consensus on 52 of 63 interventions (82.5%), of which 17 (32.7%) were voted time-dependent (11 clinical [64.7%] and six pharmacological [35.3%]). Clinical interventions included airway suction or de-obstruction, cricothyrotomy, positive pressure ventilation, chest decompression, cardiopulmonary resuscitation, defibrillation, cardioversion, pacing, and hemorrhage control. Pharmacological interventions included medication classed as sympathomimetics, caloric agents, antiarrhythmic agents, anticonvulsants, or tranquilizers.
Conclusion:
The panel reached a consensus on a definition of time-dependent care and used this to identify prehospital interventions that could serve as an instrument to improve care and system performance.
Malnutrition results from inadequate nutrient intake, assimilation or utilisation, negatively impacting clinical outcomes and quality of life. It likely compromises gut barrier integrity, increasing intestinal permeability (IP), which impairs nutrient absorption or utilisation and increases the risk of infections and inflammation. This systematic review aims to examine the current evidence on the association between malnutrition and IP, identifying existing research gaps. A systematic search was conducted on PubMed, Scopus and Web of Science up to June 2024. According to PECOS strategy, ‘P’ = malnourished individuals or at risk of malnutrition, assessed for intestinal permeability; ‘E’ = malnutrition or risk of malnutrition; ‘C’ = well-nourished individuals; ‘O’ = increased intestinal permeability; and ‘S’ = all study types. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist was followed, and Study Quality Assessment Tools (NIH) were used for methodological quality analysis. Sixteen studies met the inclusion criteria, with a moderate/high risk of bias. Malnourished individuals exhibited increased IP across various conditions (e.g. anorexia nervosa, cancer and liver cirrhosis) or setting (hospital and community). A wide heterogeneity was observed in malnutrition assessment tools, which consider different parameters such as body mass index, body weight loss and food intake. Similarly, diverse biomarkers/methods for assessing IP, including direct and indirect approaches, were used. Despite methodological heterogeneity, findings show an association between malnutrition and increased IP. Standardised research, including comprehensive biomarker panels, is needed to improve comparability, facilitating the development of targeted interventions for preventing malnutrition and managing its complications.
This book provides a concise and up-to-date guide to Cognitive Behavioural Therapy (CBT), from the history and supporting theory, through to the most recent empirical evidence and practical aspects of delivery. Starting with an overview of the structure of CBT, practitioners can utilise this detailed guide to deliver therapy in clinical practice, whilst its coverage of various adaptations of CBT, such as group therapy and working with older adults, allow therapy to be tailored to different settings with different timeframes attached. Covering all the major CBT protocols necessary to work with a wide range of common mental health conditions. A comprehensive resource for a wide range of practitioners providing practical approaches, goals, and strategies to manage mental health problems using CBT. Part of the Cambridge Guides to the Psychological Therapies series, offering all the latest scientifically rigorous, and practical information on a range of key, evidence-based psychological interventions for clinicians.
This study aimed to determine the prevalence of paternal perinatal depression (PPND) using the Edinburgh Postnatal Depression Scale (EPDS) among fathers/co-parents at an urban obstetric hospital and identify key predictors of positive screening outcomes.
Methods:
A cross-sectional anonymous online survey was completed by 115 respondents between July 2023 and January 2024. The questionnaire included demographic and clinical items, the EPDS, and the Social Safety and Pleasure Scale (SSPS). An EPDS score ≥ 9 indicated a positive screen for depression. A composite variable for history of mental illness was created based on prior diagnosis, mental health service engagement, and medication use.
Results:
Thirty-three percent of participants screened positive for depression (EPDS ≥ 9); 17.4% had scores ≥ 12. A self-reported history of mental illness significantly predicted positive screening (OR = 4.38, p = 0.001). No significant associations were found with demographic, obstetric, or infant-related variables. Lower SSPS scores were significantly associated with higher EPDS scores.
Conclusion:
Despite limitations, in particular selection bias and small sample size, fathers and co-parents are at increased risk for depressive symptoms in the perinatal period, particularly those with a mental health history. Routine screening and inclusive models of care are needed to support paternal mental health during this vulnerable time.