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Genealogies of two linked neutral loci after a selective sweep in a large population of stochastically varying size

  • Rebekka Brink-Spalink (a1) and Charline Smadi (a2)
Abstract

We study the impact of a hard selective sweep on the genealogy of partially linked neutral loci in the vicinity of the positively selected allele. We consider a sexual population of stochastically varying size and, focusing on two neighboring loci, derive an approximate formula for the neutral genealogy of a sample of individuals taken at the end of the sweep. Individuals are characterized by ecological parameters depending on their genetic type, and governing their growth rate and interactions with other individuals (competition). As a consequence, the `fitness' of an individual depends on the population state and is not an intrinsic characteristic of individuals. We provide a deep insight into the dynamics of the mutant and wild-type populations during the different stages of a selective sweep.

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* Postal address: Institute for Mathematical Stochastics, Georg-August-Universität Göttingen, Goldschmidtstr. 7, 37077 Göttingen, Germany.
** Current address: Institut des Systèmes Complexes Paris Île-de-France, 113 rue Nationale, 75013 Paris, France. Email address: charline.smadi@irstea.fr
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Advances in Applied Probability
  • ISSN: 0001-8678
  • EISSN: 1475-6064
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