Future Developments: Sperm Proteomics

doi:10.1017/9781108878715.028

Chapter 25 - Future Developments: Sperm Proteomics

Published online by Cambridge University Press: 05 April 2021

Saradha Baskaran and

Edited by

Ralf Henkel and

Ashok Agarwal: Affiliation:
The Cleveland Clinic Foundation, Cleveland, OH
Ralf Henkel: Affiliation:
University of the Western Cape, South Africa
Ahmad Majzoub: Affiliation:
Hamad Medical Corporation, Doha

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Summary

Spermatozoa are mature male gametes that are produced in the testes of a healthy man by spermatogenesis, with further maturation of sperm taking place during their transit through the epididymis. In the human, approximately 20 to 240 million sperm are produced per day [1]. Unlike other somatic cells present in the human body, spermatozoa contain a head, neck, mid-piece and tail region. The head region contains the genetic material which is transferred to the oocyte during the fertilization process. Apart from DNA, spermatozoa also deliver additional subcellular materials such as oocyte activating factors, RNA, microRNAs and exosomal proteins that are essential for the development of the oocyte into a zygote.

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Type: Chapter
Information: Manual of Sperm Function Testing in Human Assisted Reproduction , pp. 245 - 255

DOI: https://doi.org/10.1017/9781108878715.028 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2021

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