Chronic Traumatic Encephalopathy and Traumatic Brain Injury

doi:10.1017/9781108985055.019

Chapter 19 - Chronic Traumatic Encephalopathy and Traumatic Brain Injury

from Section 2 - The Dementias

Published online by Cambridge University Press: 17 November 2025

Breton M. Asken ,

David C. Perry and

Raquel C. Gardner

Edited by

Bruce L. Miller and

Bradley F. Boeve

Show author details

Bruce L. Miller: Affiliation:
University of California, San Francisco
Bradley F. Boeve: Affiliation:
Mayo Clinic, Minnesota

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Summary

This chapter provides an overview of chronic traumatic encephalopathy (CTE), a neurodegenerative disease associated with repetitive head trauma. It discusses the historical background of CTE, its neuropathology, clinical features, and epidemiology. The chapter also explores the current understanding of CTE staging and common co-pathologies. It highlights the challenges in diagnosing and monitoring CTE in living patients and the ongoing research efforts to develop biomarkers for early detection. The chapter concludes by discussing the prevention, treatment, and future directions in CTE research. It is important to recognize the risks of head trauma and implement measures to reduce the incidence of CTE and other neurodegenerative diseases associated with head trauma.

Keywords

chronic traumatic encephalopathy (CTE)repetitive head trauma neuropathology epidemiology biomarkers traumatic encephalopathy syndrome (TES)prevention treatment

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Type: Chapter
Information: The Behavioral Neurology of Dementia , pp. 321 - 341

DOI: https://doi.org/10.1017/9781108985055.019 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2025

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