Book contents
- Frontmatter
- Contents
- Acknowledgments
- Contributor
- 1 Rationale for transplantation
- 2 Types of transplantation
- 3 Human leukocyte antigen matching in allogeneic transplantation
- 4 Stem cell source
- 5 Pretransplant evaluation and counseling of patient and donor
- 6 Conditioning regimens
- 7 Stem cell infusion
- 8 ABO compatibility
- 9 Engraftment
- 10 Preventative care
- 11 Transplant-related complications
- 12 Overview of acute and chronic graft-versus-host disease
- 13 Acute graft-versus-host disease and staging
- 14 Graft-versus-host disease prophylactic regimens
- 15 Treatment guidelines for acute graft-versus-host disease
- 16 Chronic graft-versus-host disease
- 17 Engraftment syndrome
- 18 Infectious disease
- 19 Graft rejection and failure
- 20 Gastrointestinal complications
- 21 Oral health in stem cell transplantation
- 22 Pulmonary complications
- 23 Veno-occlusive disease
- 24 Special transfusion-related situations
- 25 Cardiovascular complications
- 26 Neurologic complications
- 27 Cystitis
- 28 Donor lymphocyte infusion
- 29 Transplantation: regulation and accreditation
- Index
- References
10 - Preventative care
Published online by Cambridge University Press: 05 November 2013
Book contents
- Frontmatter
- Contents
- Acknowledgments
- Contributor
- 1 Rationale for transplantation
- 2 Types of transplantation
- 3 Human leukocyte antigen matching in allogeneic transplantation
- 4 Stem cell source
- 5 Pretransplant evaluation and counseling of patient and donor
- 6 Conditioning regimens
- 7 Stem cell infusion
- 8 ABO compatibility
- 9 Engraftment
- 10 Preventative care
- 11 Transplant-related complications
- 12 Overview of acute and chronic graft-versus-host disease
- 13 Acute graft-versus-host disease and staging
- 14 Graft-versus-host disease prophylactic regimens
- 15 Treatment guidelines for acute graft-versus-host disease
- 16 Chronic graft-versus-host disease
- 17 Engraftment syndrome
- 18 Infectious disease
- 19 Graft rejection and failure
- 20 Gastrointestinal complications
- 21 Oral health in stem cell transplantation
- 22 Pulmonary complications
- 23 Veno-occlusive disease
- 24 Special transfusion-related situations
- 25 Cardiovascular complications
- 26 Neurologic complications
- 27 Cystitis
- 28 Donor lymphocyte infusion
- 29 Transplantation: regulation and accreditation
- Index
- References
Summary
Preventative care will vary onthe basis of transplant type, institutional guidelines, protocol,medications, and pretransplant viral studies.
Infection prophylaxis
Please see Chapter 18 oninfectious diseases.
Hospital infection control
Hospital personnel shouldfollow standard infection control and Center for Disease Control (CDC)guidelines to prevent nosocomial infections. The efficacy of differenttransplant-specific precautions in preventing nosocomial infections has notbeen studied. Hand washing continues to be the single most critical and efective procedure for preventing infection. If gloves are utilized, theyshould be changed between patients. All equipment should be sterilized ordisinfected and Environment Protection Agency (EPA) registered.
Allogeneic hematopoietic stemcell transplantation (HSCT) patients should be placed in private rooms thathave >12 air exchanges per hour and high-efficiency particulate airfilters (HEPA) that are capable of removing particles ≥0.3 μm in diameter.It is generally considered good practice to treat all immunocompromisedpeople in HEPA-filtered rooms, although the data are less clear forautologous HSCT than for allogeneic HSCT.
Information
- Type
- Chapter
- Information
- Manual of Stem Cell and Bone Marrow Transplantation , pp. 40 - 46Publisher: Cambridge University PressPrint publication year: 2013
References
.
MMWR
2011; 60:
1–64.
Guidelines for
preventing opportunistic infections among hematopoietic stem cell transplant
recipients. MMWR 2000; 49: rr-10: 1–128.
, , , et al. Vaccination of allogeneic
haematopoietic stem cell transplant recipients: report from the
international consensus conference on clinical practice in chronic
GVHD. Vaccine
2011; 29:
2825–33.CrossRefGoogle ScholarPubMed
, , , et al. Vaccination of hematopoietic cell
transplant recipients. Bone Marrow
Transplant
2009; 44:
521–6.CrossRefGoogle ScholarPubMed
, , , et al. Guidelines for preventing
infectious complications among hematopoietic cell transplantation
recipients: a global perspective. Biol
Blood Marrow Transplant
2009; 15:
1143–238.CrossRefGoogle ScholarPubMed
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