To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Scholars recognize the important role that diasporas play in conflict dynamics, including efforts to build peace in conflict-affected communities. Broader academic research emphasizes a focus on local conditions and actors, as well as site-specific understandings of peace and peacebuilding practices. This focus on specific communities and contexts often draws on qualitative, narrative-driven data, predominantly collected through interviewing. This article identifies some of the core challenges related to data collection encountered during semi-structured interviews in a study of Somali diaspora members in Melbourne, Australia. We emphasize how issues associated with cross-cultural and gendered understandings of concepts related to peacebuilding can affect each stage of a research project, from the preliminary collection of data to the analysis and discussion of research implications. Specifically, we address challenges related to instances of conceptual dissonance that occur when researchers employ cross-cultural and gendered concepts—in this case, peace, peacebuilding, and leadership. The findings will benefit conflict researchers who work with socially distant groups and ethnically divided populations more broadly, along with those who employ interpretivist methodologies that focus on how meaning making might ultimately influence peacebuilding practices and outcomes.
What is the nature of religious faith as understood in the Abrahamic tradition? This article suggests a novel answer to this question. To this end, I first outline five desiderata, characterized by appealing to conceptions of faith in both the Islamic and Christian traditions, which I think every adequate account of faith should satisfy. These five desiderata are: (1) explaining the principle of the relationship between faith and religious actions; (2) accounting for the maxim of the relationship between faith and moral virtues; (3) showing how the thesis of the priority of faith over knowledge can be the case; (4) providing a basis for the axiom of the gradability of faith; and (5) solving the dilemma of faith as a gift or an achievement. Then I make my case and develop a model of faith that satisfies all five desiderata. Following the accounts in the literature that describes faith as a kind of know-how, the central idea of my suggestion is that religious faith is partly constituted by intellectual, practical, and moral skills.
In 2018, Nigeria began the implementation of a cash transfer programme (CCT) for poor and vulnerable people. We evaluated the impact of cash transfer on household livelihood outcomes in Nigeria. Using multistage cluster sampling methodology, beneficiaries and non-beneficiaries within the same locality were randomly selected to participate in a survey to assess the impact of cash transfer on food security and food diversity.
When gender, marital status, educational status, and age were controlled, beneficiaries were about three times more likely than non-beneficiaries to report experiencing little or no hunger. Children 0–59 months of beneficiaries were twice likely to have at least three meals a day compared to children of non-beneficiaries. Difference in differences regression analysis showed that on the average, beneficiaries of the cash transfer significantly consumed more diverse food than non-beneficiaries. Beneficiaries of the CCT experienced fewer episodes of severe hunger, have more meal frequency, and higher household dietary diversity than non-beneficiaries. This shows that the CCT programme is effective and can directly mitigate adverse effects of malnutrition with its long-term negative impact on children and thus must be expanded to more vulnerable people across all states in Nigeria.
From 2013 to 2015, China gradually established nationwide air quality monitoring stations and began to release real-time air pollution information to the public. We exploit step-by-step environmental regulations across cities to identify the effects of information disclosure on air pollution. We find that information disclosure significantly decreases the concentrations of PM2.5 and PM10. Through mechanism analysis, we find that information disclosure raises the level of government awareness, increases the amount of investments in air pollution prevention and control, stimulates green innovation, and forces heavily polluting enterprises to shut down. Additionally, we find evidence that the effectiveness of information disclosure varies across cities.
The new terricolous lichen species Thamnolecania yunusii Halıcı, Güllü, Bölükbaşı & Kahraman, which is characterised by its cream to greyish brown granulose-crustose thallus without vegetative propagules, is described from Horseshoe Island in the South-West Antarctic Peninsula region. All Thamnolecania species are known only from the Antarctic. The only species of the genus with a crustose thallus is T. racovitzae, but it differs from T. yunusii by growing on rocks, having an effuse to subeffigurate thallus that is sometimes isidiate and with shorter and narrower ascospores (c. 15 × 3.5 µm vs. 15.5–19.5 × 3.5–5.5 µm). The nrITS, mtSSU and RPB1 gene regions of the new species were studied and the phylogenetic position of the species was shown to be in the same clade as Thamnolecania gerlachei, T. brialmontii and T. racovitzae, but occurs on a different branch from these species. As T. yunusii is an Antarctic endemic, like the other Thamnolecania species, and most of the morphological characters fit well with this genus, we describe this new species under the genus Thamnolecania.
This research paper presents an application of the integrated process and product design (IPPD) approach for selecting the best joint configuration for dissimilar material joining in the early product design phase. The proposed methodology integrates the multi-criteria decision making (MCDM) approach with quality function deployment (QFD) to identify the key criteria for joint selection, including load-carrying capacity, size, cost per joint, ease of manufacturing, time consumption and deformation. Three types of joints (rivet, weld and adhesive) and two hybrid joints (adhesive-weld and adhesive-rivet) are considered for three dissimilar material configurations: carbon fiber-reinforced plastic (CFRP) aluminum, CFRP steel, and aluminum-steel. QFD is utilised to transform job requirements into design criteria, and in the second phase, the Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) is employed to choose the optimal joint configuration based on the weighted criteria acquired in the previous phase. The selected joint configuration is then validated through experimental study. The findings demonstrate that the proposed IPPD approach with QFD-TOPSIS techniques is highly effective for selecting mechanical joints for dissimilar material joining in the early design phase. The study concludes that the adhesive-rivet hybrid joint is the optimal solution among all alternatives. The proposed methodology can ultimately lead to improved product reliability and performance, as well as reduced development time and cost.
This article deals with the impact of intra-party transformations and access to power on the visions of political participation of activists taking part in populist anti-establishment parties with a strong emphasis on digital participation, using the Five Star Movement (M5S) as a case study. Going beyond studies conceiving the M5S as a populist and digital party, we argue that activists support a democratic ideal based on a civic culture involving a demanding role for ordinary citizens, who should be highly interested in politics and involved locally on a day-to-day basis. A negative vision of the Italian citizen judged as incapable of playing this role accompanies this ideal. Our article also demonstrates how political involvement in the M5S transformed the visions of activists, making them warier of direct democracy and more disillusioned about their fellow citizens. The analysis relies on qualitative semi-directed interviews with former and current M5S activists with diversified socio-demographics, political and participation trajectories in two Italian regions. More broadly, our article shows that the effects of entering government and intra-party reforms reinforcing the leadership at the expense of local activists are particularly strong in anti-establishment parties and clash with the conceptions of participation supported by activists.
Abnormalities in the zona pellucida (ZP) adversely affect oocyte maturation, embryo development and pregnancy outcomes. However, the assessment of severity is challenging. To evaluate the effects of different degrees of ZP abnormalities on embryo development and clinical outcomes, in total, 590 retrieval cycles were scored and divided into four categories (control, mild, moderate and severe) based on three parameters: perivitelline space, percentage of immature oocytes and percentage of oocytes with abnormal morphology. As the severity of abnormal ZP increased, both the number of retrieved oocytes and mature oocytes decreased. The fertilization rate did not differ significantly among groups. The rates of embryo cleavage and day-3 high-quality embryos in the mild group and the moderate group did not vary significantly between the two groups but were significantly higher than those in the severe group. The blastulation rates of the abnormal ZP groups were similar; however, they were lower than those of the control group. Moreover, the cycle cancellation rate of the severe abnormal ZP group was as high as 66.20%, which was significantly higher than that of the other three groups. Although the rates of cumulative clinical pregnancy and live births were lower than those in the control group, they were comparable among the abnormal ZP groups. There were no differences in the neonatal outcomes of the different groups. Together, ZP abnormalities show various degrees of severity, and in all patients regardless of the degree of ZP abnormalities who achieve available embryos, there will be an opportunity to eventually give birth.
The root-knot nematodes (RKN) (Meloidogyne graminicola) are a devastating threat to rice worldwide. The cultivated germplasm is either susceptible or moderately resistant to rice RKN. Therefore, there is a need to identify resistance sources against M. graminicola as an eco-friendly management strategy. The present study evaluated the host response of Oryza sativa genotypes comprising basmati, non-basmati improved varieties, their advanced breeding lines (83) and Oryza glaberrima accessions (42) against M. graminicola in the nematode-infested plot for two consecutive years. All O. sativa genotypes exhibited susceptible responses, while O. glaberrima accessions showed variable levels of resistance. Three of the O. glaberrima accessions (IRGC102196, IRGC102538 and IRGC102557) were highly resistant. M. graminicola significantly affected plant growth parameters in susceptible genotypes compared to resistant O. glaberrima accessions. The results were supported by histopathological studies that showed apparent giant cell formation in PR121 while penetration and development of M. graminicola juveniles were low in the O. glaberrima acc. IRGC102196. In silico analysis indicated that none of the reported nematode resistance genes from different crops had homology with the rice genome. The two anti-nematode genes (Oryzacystatin-I and Oryzacystatin-II) from O. sativa japonica revealed homology with O. sativa cv. PR121 and O. glaberrima acc. IRGC102206. Comparative analysis of these genes between PR121 and O. glaberrima acc. IRGC102206 resulted in the identification of SNPs/InDels that could be associated with nematode resistance. The identified SNPs/InDels could be validated, and further molecular studies are needed to provide insights into the resistance mechanism against rice RKN.
The use of repeated measures analysis of variance (ANOVA) options for the analysis of in vitro ruminal fermentation gas production profiles is illustrated. Because of the different variances and covariance structures among profile observations, ordinary ANOVA for more than two-time points is not recommended. To mitigate this problem, the Greenhouse–Geisser epsilon correction can be applied to reduce the degrees of freedom, inflated by violation of the sphericity assumption, for F ratio probability calculations. After this correction, the Box–Greenhouse–Geisser ANOVA (modified ANOVA) layout appears similar to the layout of a split-plot design ANOVA with whole plots divided into subplots (incubation time). Any F tests in the main plot part are valid but F tests involving the time factor from the subplot part need modification because time factor, by its very nature, cannot be allocated at random. Application of multivariate ANOVA, distance multivariate ANOVA, ante-dependence and mixed model analysis are also considered. All these options lend themselves to wide application in the applied biological sciences.
In this paper, we consider four scenarios for economic optimal management of a fisheries resource by a high sea and coastal fleet segment. These scenarios differ with respect to whether a common or two separate fish stocks are considered and whether the profit from land-based processing is included. The model is parametrized using the Greenland halibut fishery on the west coast of Greenland as an empirical case. For this fishery, we show that the relative ranking of the optimal high sea industry harvest and profit compared to the coastal industry harvest and profit depends on the chosen scenario. When comparing the scenarios for optimal management and the actual situation, we find that the fish stock tends to be overexploited.
The problem of classifying elliptic curves over $\mathbb Q$ with a given discriminant has received much attention. The analogous problem for genus $2$ curves has only been tackled when the absolute discriminant is a power of $2$. In this article, we classify genus $2$ curves C defined over ${\mathbb Q}$ with at least two rational Weierstrass points and whose absolute discriminant is an odd prime. In fact, we show that such a curve C must be isomorphic to a specialization of one of finitely many $1$-parameter families of genus $2$ curves. In particular, we provide genus $2$ analogues to Neumann–Setzer families of elliptic curves over the rationals.
Catecholaminergic polymorphic ventricular tachycardia is an ion channelopathy, caused by mutations in genes coding for calcium-handling proteins. It can coexist with left ventricular non-compaction. We aim to investigate the clinical and genetic characteristics of this co-phenotype.
Methods:
Medical records of 24 patients diagnosed with catecholaminergic polymorphic ventricular tachycardia in two Chinese hospitals between September, 2005, and January, 2020, were retrospectively reviewed. We evaluated their clinical and genetic characteristics, including basic demographic data, electrocardiogram parameters, medications and survival during follow-up, and their gene mutations. We did structural analysis for a novel variant ryanodine receptor 2-E4005V.
Results:
The patients included 19 with catecholaminergic polymorphic ventricular tachycardia mono-phenotype and 5 catecholaminergic polymorphic ventricular tachycardia-left ventricular non-compaction overlap patients. The median age of onset symptoms was 9.0 (8.0,13.5) years. Most patients (91.7%) had cardiac symptoms, and 50% had a family history of syncope. Overlap patients had lower peak heart rate and threshold heart rate for ventricular tachycardia and ventricular premature beat during the exercise stress test (p < 0.05). Sudden cardiac death risk may be higher in overlap patients during follow-up. Gene sequencing revealed 1 novel ryanodine receptor 2 missense mutation E4005V and 1 mutation previously unreported in catecholaminergic polymorphic ventricular tachycardia, but no left ventricular non-compaction-causing mutations were observed. In-silico analysis showed the novel mutation E4005V broke down the interaction between two charged residues.
Conclusions:
Catecholaminergic polymorphic ventricular tachycardia overlapping with left ventricular non-compaction may lead to ventricular premature beat/ventricular tachycardia during exercise stress test at lower threshold heart rate than catecholaminergic polymorphic ventricular tachycardia alone; it may also indicate a worse prognosis and requires strict follow-up. ryanodine receptor 2 mutations disrupted interactions between residues and may interfere the function of ryanodine receptor 2.
Research has demonstrated that implementation of Nocebo Hypothesis Cognitive Behavioural Therapy (NH-CBT) achieved full symptom remission in 93% of people with Functional Neurological Symptoms Disorder (FNSD), most of them exhibiting motor symptoms. The basis for NH-CBT is consistent with a predictive coding aetiological model of FNSD. This idea is transparently shared with people with FNSD in the form of telling them that their symptoms are caused by a nocebo effect, usually followed by some physical activity that aims to change the person’s belief about their body.
Aims:
To demonstrate that a version of NH-CBT can also be effective in eliminating or reducing non-epileptic seizures (assumed to be a sub-type of FNSD).
Method:
A consecutive case series design was employed. Participants were treated with NH-CBT over a 12-week period. The primary outcome measure was seizure frequency. Numerous secondary measures were employed, as well as a brief qualitative interview to explore participants’ subjective experience of treatment.
Results:
Seven out of the 10 participants became seizure free at least 2 weeks before their post-treatment assessment, and all stayed seizure-free for at least 5 months. Six of those seven remained seizure free at 6-month follow-up. There were large positive effect sizes for the majority of secondary measures assessed.
Conclusions:
This case series provides evidence of feasibility and likely utility of NH-CBT in reducing the frequency of non-epileptic seizures.
Childhood infections have been shown to stunt growth, contribute to malnutrition and reduce cognition in early adulthood. This study aimed to assess relationships between early life infections and childhood cognition at age 11 years in the Newcastle Thousand Families Study (NTFS). The analysis included 741 members from the NTFS who had complete data for infections between birth and 5 years, and the 11-plus examinations. School records from the 11-plus examinations showed cognitive (IQ), English (EQ) and arithmetic (AQ) abilities. Housing conditions, overcrowding, birth order and social class were recorded at birth. Helicobacter pylori seropositivity was measured at age 49–51 years. Multivariable linear regression was used to examine relationships between infections and cognition. The total number of infections in the first 5 years of life was not significantly associated with IQ, EQ or AQ, nor were there significant relationships between cognitive outcomes and most infections. Tonsillitis did display a positive, significant association with IQ after adjustment for confounders (b = 6.43, 95% CI 0.92, 11.94, p = 0.022). Lower respiratory tract infections (LRTIs) showed significant negative relationships with all cognitive outcomes. H. pylori seropositivity at age 50 exhibited negative, significant relationships with EQ (p = 0.014) and AQ (p = 0.024) after adjustment for confounders. Although no significant relationship between overall infections and cognition were found, there were indications that LRTIs and gastrointestinal system infections may limit cognitive development. Given these infections remain prevalent, further research regarding severity and recurrence of infections and how they affect childhood cognition is needed.
The coronavirus disease (COVID-19) pandemic necessitated alternative methods to ensure the continuity of medical education. Our study explores the efficacy and acceptability of a digital continuous medical education initiative for medical residents during this challenging period.
Methods:
From September to December 2020, 47 out of 60 enrolled trainee doctors participated in this innovative digital Continuous Medical Education (CME) approach. We utilized the Script Concordance Test to bolster clinical reasoning skills. Three simulation scenarios, namely Advanced Trauma Life Support (ATLS), Advanced Life Support (ALS), and European Paediatric Life Support (EPLS), were transformed into interactive online sessions via Zoom™. Participant feedback was also collected through a survey.
Results:
Consistent Script Concordance Testing (SCT) scores among participants indicated the effectiveness of the online training module. Feedback suggested a broad acceptance of this novel training approach. However, discrepancies observed between formative SCT scores, and summative Multiple-Choice Questions (MCQ) assessments highlighted areas for potential refinement.
Conclusions:
Our findings showcase the resilience and adaptability of medical education amidst challenges like the global pandemic. The success of methodologies such as SCT, endorsed by prestigious bodies like the European Resuscitation Council and the American Heart Association, suggests their potential in preparing health care professionals for emergent situations. This research offers valuable insights for shaping future online CME strategies.