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It was proved by Maksimova in 1977 that exactly eight varieties of Heyting algebras have the amalgamation property, and hence exactly eight axiomatic extensions of intuitionistic propositional logic have the deductive interpolation property. The prevalence of these properties for substructural logics and varieties of pointed residuated lattices (their algebraic semantics) is far less well understood. Taking as our starting point a formulation of intuitionistic propositional logic as the full Lambek calculus with exchange, weakening, and contraction, we investigate the role of the exchange rule—algebraically, the commutativity law—in determining the scope of these properties. First, we show that there are continuum-many varieties of idempotent semilinear residuated lattices that have the amalgamation property and contain non-commutative members, and hence continuum-many axiomatic extensions of the corresponding logic that have the deductive interpolation property in which exchange is not derivable. We then show that, in contrast, exactly 60 varieties of commutative idempotent semilinear residuated lattices have the amalgamation property, and hence exactly 60 axiomatic extensions of the corresponding logic with exchange have the deductive interpolation property. From this latter result, it follows also that there are exactly 60 varieties of commutative idempotent semilinear residuated lattices whose first-order theories have a model completion.
For individuals fleeing oppressive regimes, the support from migrant communities often serves as a lifeline. Although prior research has mostly focused on how host societies respond to migration, this study shifts the lens to examine how migrants themselves decide whom to support in contexts of authoritarian repression and war. Drawing on an original survey of 2,036 Russian emigrants residing in more than 60 countries, which features a conjoint experiment, as well as 60 in-depth interviews, we investigate the criteria underlying migrant-to-migrant assistance. Russian migrants prefer to assist those emigrants who are fleeing because of political persecution or their dissenting political views, rather than those leaving for economic reasons. We suggest that this preference reflects not only political solidarity with antiwar emigrants but also a strategic effort to reshape the image of the Russian diaspora in response to nationality-based discrimination. In addition, contrary to the literature, migrants, driven by perceptions of vulnerability and a sense of guilt over Russia’s wartime actions, offer more support to members of ethnic minorities than to ethnic Russians.
There are increasing calls for greater availability of plant genetic resources (PGR) for use in plant breeding to help counter the adverse impacts of a changing climate and threats from pests and diseases, particularly in a context of reduced agricultural inputs, and the needs of the increasing human population. Managing and promoting ex situ and in situ conservation of PGR requires an effective data and informatics foundation. However, in situ data management is particularly undeveloped, especially when compared to ex situ documentation. The work presented here is a consolidated descriptor list to support in situ conservation of PGR. The consolidated PGR descriptor list is based on numerous partial lists collated from historic PGR activities, biodiversity conservation and protected area networking activities. New descriptors for in situ conservation activities were developed where gaps were identified. The draft consolidated PGR descriptor list was reviewed and revised through a process of consultation with experts in PGR documentation and in situ conservation. In total, 171 descriptors were identified, of which seven are defined as mandatory, 47 are defined as core descriptors and 29 are newly developed descriptors for in situ conservation of PGR. The descriptors cover all aspects of in situ conservation, from gathering passport data (for which there are already well-established descriptors), to monitoring and managing crop wild relative and landrace populations. Recommendations are made for the most effective use and future development of descriptors and how they could be used to further develop and support in situ PGR conservation implementation.
Narratives possess a particular ability both to encapsulate and engender political/ideological aims. The extreme-right is aware of the pedagogic potential of fiction; however, their fiction is only rarely examined from a discourse-analytic perspective. This article analyses a short story written and distributed by a US neo-Nazi organisation. First, my analysis examines: narrative action processes, that is, the (transitive and intransitive) actions of characters, which drive narrative change; and modal tokens relevant to the evaluative function of the narrative. Second, I argue that narrative action processes and modal tokens represent the ‘warp and woof’ of narrative, since they (i) demonstrate how stories connect events, over time, and (ii) appraise the social/political meaning of these events. My analysis has significance for the discourse-analytic understanding of narrative more generally, as well as the specific ways that fantasies of agency and violence function in this story, to incite political action. (Narrative, narrative action processes, modal tokens, extreme-right, neo-Nazi fantasy)
This paper provides a close reading of Phylarchus Fragment 44 (Ath. 4.20–1, 141F–42f) against the backdrop of the Hellenistic discourse of kingship, on the one hand, and the developments in the Spartan kings’ approach to monarchical rule, on the other. It argues that the characterisation of Cleomenes in Fragment 44 is rooted in a discourse on kingship that was contemporaneous with Phylarchus, and that his text’s prevailing theme is the king’s σωφροσύνη as opposed to ὕβρις.
To explore the multilevel factors (barriers and facilitators) influencing maternal and child nutrition (MCN) from community perspectives using the Socioecological Model (SEM) as the guiding framework.
Design:
An exploratory qualitative study combining semi-structured online interviews (Microsoft Teams) and photovoice method. Data were audio-recorded, translated, transcribed and analysed inductively using Braun and Clarke’s thematic approach, with final themes mapped to the SEM levels.
Settings:
Two semi-urban communities in Ado-Odo Ota Local Government Area, Ogun State, Nigeria.
Participants:
Twenty-five participants (aged 25–75 years), including pregnant and lactating mothers, fathers, grandmothers, community leaders, and health workers, were recruited through purposive and snowball sampling.
Results:
Despite basic nutrition awareness, maternal diets were predominantly carbohydrate-based while infant feeding was characterised by delayed breastfeeding initiation, prelacteal feeding, and suboptimal complementary feeding practices. At the interpersonal level, strong familial and community support was evident, however, grandmothers strongly influenced dietary taboos and health-seeking decisions. Organisational barriers, including poor facilities and negative staff attitudes, reduced trust in primary healthcare centres and encouraged reliance on private clinics and traditional providers. Community-level challenges such as poverty, rising food prices, unreliable water supply and poor waste disposal systems increased the risk of malnutrition. Nonetheless, some households demonstrated resilience through home gardening, bulk food purchasing and adequate hygiene practices.
Conclusions:
MCN is shaped by interconnected factors. Sustainable progress requires moving beyond individual knowledge transfer towards integrated, system-based actions that strengthen nutrition and health services, improve access to diverse foods, safe water and sanitation, and leverage existing community strengths.
This study aims to determine the current status of the obesity epidemic in Türkiye from a global perspective by examining gender-specific socio-economic inequalities at national and regional socio-economic development (SED) levels.
Design:
A cross-sectional analysis was conducted using data from the 2022 Türkiye Health Survey, employing weighted binary logistic regression models, age-standardised prevalence estimates for national obesity prevalence and model-based age-adjusted prevalence estimates for regional comparisons, with analyses stratified by sex.
Setting:
Türkiye.
Participants:
Data included 20 725 nationally representative adults aged 20 years and older (10 808 women and 9917 men).
Results:
The national age-standardised obesity prevalence was substantially higher (OR: 1·558; 95 % CI: 1·556, 1·560) in women (28·0 %) than men (18·4 %). In low-SED regions, the gender disparity (women 28·4 %, men 17·9 %) was larger. Higher education was consistently associated with lower obesity risk, more pronounced in women and low-SED regions. The income–obesity relationship was complex. An inverted U-shaped pattern across income quintiles was observed among men in high regional SED and among women both nationwide and across all levels of regional SED.
Conclusions:
As of 2022, Türkiye maintains a high obesity prevalence reflecting socio-economic patterns typical of developing countries experiencing nutritional transition. The epidemic stage varies by regional SED, emphasising the necessity for prevention strategies designed with a focus on socio-economic determinants, regional and gender sensitivity.
Subthreshold depression (StD) is considered a prodromal stage of major depressive disorder (MDD). This study aims to investigate the neurobiological mechanisms of StD by analyzing functional connectivity (FC) and cognitive function in comparison to MDD.
Methods
A total of 153 StD individuals, 188 MDD patients, and 110 healthy controls (HCs) were studied using resting-state functional magnetic resonance imaging (fMRI). Whole-brain FC was calculated using seeds from the default mode network (DMN), salience network (SN), executive control network, and affective network (AN). Cognitive function was assessed across seven domains.
Results
StD showed only a deficit in social cognition, while MDD exhibited multidomain cognitive impairments compared to HCs. Both MDD and StD exhibited reduced FC between the right anterior insula (AI) and the left inferior frontal gyrus (IFG), and increased FC between the right subcallosal cingulate cortex and the left posterior cingulate cortex (PCC), key areas of the SN and AN, compared to HCs. MDD particularly showed decreased connectivity between the left PCC and the left middle temporal gyrus, and within the left PCC, while no abnormal FC of the DMN was found in StD. Altered AI-IFG FC was positively correlated with social cognition in StD.
Conclusions
Abnormal connectivity patterns of the SN and AN may contribute to the development of depressive symptoms in StD and MDD, while altered FC of the DMN may be involved in the onset of the disease. A social cognition deficit appeared first in StD, relating to the abnormal connectivity of the SN.
In the literature, the Rule of Law (ROL) is mainly explained, and its value justified, by reference to its support for a liberal conception of human agency. As such, the connection between the ROL and legitimacy is normally considered contingent if the conception of the ROL is thin. It can be rendered necessary, it seems, only by a substantive conception that incorporates other political ideals, notably democracy. Without recourse to such a move, this article defends a necessary ROL-legitimacy connection by exploring the ROL’s contribution to the task of pacification, which, I argue, is inherent in the claim of legitimacy. My interpretation re-orients the ROL’s foundational value from the liberal conception of human agency to politically inspired fear and summa mala. The paradigmatic shift is in line with the realism approach to political theory which derives and explains moral claims in political theories from considerations of basic political necessity.
Depending on what levels of government and actors in a political system one focuses upon, democratic innovations might seem thriving or waning. This emerges clearly when looking at the main trajectories of democratic innovation in Italy. Compared to other liberal democracies, at the national level, Italy is a laggard; yet, a more dynamic landscape of democratic innovations exists at the local level. Some regions have drafted pioneering legislation institutionalising participatory and deliberative practices and numerous councils have adopted participatory innovations, early and consistently over time. Going beyond institutions, social movements have also been very influential with activists developing their own democratic innovation repertoires, which was especially clear in the movement for the commons. Positive and negative trajectories of democratic innovation may coexist across different actors (e.g., governments and civil society.) and levels of government in Italy. However, when these actors enter in contact with each other, state institutions might use democratic innovations against democratic engagement. We reflect on the implications of this situation for future trajectories of democratic innovation in Italy.
Les partis politiques adoptent des techniques de marketing dans l’élaboration et le déploiement de leurs campagnes électorales. Parmi elles, on note le recours au microciblage politique. En contexte canadien, cette approche n’a pas été étudiée au palier municipal. Cet article vise à combler cette lacune. Des entretiens semi-dirigés ont été réalisés auprès de 17 stratèges actifs dans quatre grandes villes québécoises lors des élections municipales de 2021. L’analyse de leurs récits montre qu’en dépit de la présence de réflexions et de comportements apparentés à une logique de marketing politique, les campagnes étudiées n’ont pas recours au microciblage. Elles se concentrent plutôt principalement sur le pointage et la mobilisation électorale, sans mettre à profit les données collectées sur l’électorat. Cette situation pourrait toutefois évoluer advenant une professionnalisation des campagnes dans les cycles électoraux à venir.
Prolonged armed conflict profoundly impacts children’s mental health. This study investigated elevated rates of post-traumatic stress disorder (PTSD) symptoms among displaced Palestinian youth residing in Qatar. A cross-sectional study included 350 Palestinian children and adolescents aged 8–18 years displaced from Gaza. The Child PTSD Symptom Scale – Self-Report Version for DSM-5 (CPSS-5) and a Demographic and Resilience Questionnaire were used. Descriptive statistics and multiple linear regression identified factors associated with PTSD symptoms.
Results
It was found that 54.9% of participants met the threshold for probable PTSD (CPSS-5 score ≥31). Intrusion and arousal symptoms had the highest average severity scores. Factors associated with higher PTSD severity included formal education, physical injury during the war and witnessing death, particularly that of close relatives.
Clinical implications
The findings emphasise the urgent need for accessible, culturally appropriate and sustained mental health interventions. Longitudinal research is needed to understand long-term trajectories and inform comprehensive support systems.
This article proposes a theory of mosque regulation to explain why state-mosque relations vary at the subnational level in Europe, using Belgium’s regions as comparative cases. Focusing on Belgium’s policy of formal recognition for mosque-communities, I argue that regulatory outcomes emerge from strategic interactions between local officials and mosque leaders, each responding to distinct audience pressures. I draw from original data on 270 mosques and 52 semi-structured interviews to argue that partisanship shapes regulatory practices: left-leaning governments pursue cooperative regulation to court minority voters, while right-wing officials adopt combative approaches to appease anti-Muslim constituencies. Mosque leaders, in turn, consider reputational costs when deciding whether to engage with the state, often pursuing recognition not for material gain but to signal trustworthiness to the broader public. These findings contribute to an emerging scholarship on the political behavior of Muslim leadership, as well as to broader literatures on minority incorporation and subnational governance.
To describe the perception of primary care (PC) among medical students from two universities in Peru.
Methods:
A cross-sectional study was conducted among third- to seventh-year medical students from two universities in Lima, Peru. A questionnaire was applied to evaluate perceptions of PC. Crude and adjusted prevalence ratios (aPR) with their 95% confidence intervals (95% CI) were calculated to assess factors associated with a favorable perception.
Results:
Data from 418 medical students were analyzed (women: 60.8%, mean age: 23.4 years). Only 2.2% expected to work in PC after graduation. Regarding perceptions of PC, 82% agreed or strongly agreed that PC is a preparatory step toward medical residency, 55% felt cases were less interesting, and 44% believed the income was lower compared to hospital work. Being enrolled at Universidad Peruana Unión (aPR: 3.35, 95% CI: 1.85–6.05) and having completed an external rotation in PC (aPR: 1.36, 95% CI: 1.03–1.80) were associated with a favorable perception.
Conclusion:
Among the assessed students, most viewed PC as a step toward residency, and nearly half considered cases less interesting and income lower compared to hospital work. A favorable perception was associated with university affiliation and having completed external rotations in PC during training.
Orthopaedic inpatients have distinct clinical traits. This study aimed to quantify the burden of nosocomial infections (NIs) on orthopaedic patients. A nested case–control study (2022–2024) at the China National Orthopaedic Medical Center compared orthopaedic inpatients with and without NIs and matched cases and controls 1:3 to evaluate the burden of NIs. A national economic burden analysis was subsequently conducted under various scenarios. Among 120,764 eligible patients, 338 (0.28%) developed NIs. A total of 321 cases were matched with 916 controls. The economic and temporal burdens of NIs are US$2,100 and 5 days per case respectively. Haematologic NIs had the highest additional cost (US$4,295) and the second longest extended stay (9 days). In terms of initial hospitalisations and readmissions, surgical site infections extended hospital stays by 20 days and increased costs by US$4,881. The top three diagnosis-related groups (DRGs) with high burdens are ZC11, ZJ15, and IE21 for costs and ZJ15, IE21, and IB19 for duration. In the mixed-region scenario, orthopaedic specialty hospitals nationwide incur US$5.23 million in direct medical costs annually because of NIs. These findings indicate that NIs significantly affect orthopaedic patients both individually and nationally, necessitating focused prevention and control for high-burden DRGs and specific infections.
People with psychosis have a life expectancy that is reduced by 15 years, mainly owing to preventable physical illnesses of which obesity is a precursor. Obesity is three times more common in individuals with psychosis, and antipsychotics are an important cause. Prediction could individualise obesity treatment, but current models are not fully actionable for individuals.
Aims
To test whether antipsychotic-induced weight increase at 1 year is causally mediated by weight change in the first 12 weeks of treatment, and then develop and internally validate a causal actionable prediction pathway to prevent antipsychotic-induced obesity.
Method
This was a post hoc analysis of a clinical trial of olanzapine versus haloperidol which recruited 263 participants with first-episode psychosis. We conducted two distinct analyses: causal mediation and prediction modelling, within which there were two sequential models (a baseline model to predict 12-week outcome and a 12-week model to predict 1-year outcome), followed by counterfactual prediction. In the first analysis, we used parallel causal mediation analysis to determine the natural direct and indirect and total effects of antipsychotic choice on weight in 97 participants, considering two mediators: weight change from 0 to 12 weeks, and weight change from 12 to 52 weeks. In the second analysis, we first developed a baseline causal actionable prediction model to predict weight gain at 12 weeks in 172 participants and then a 12-week model to predict obesity at 1 year in 97 of the participants. Finally, we demonstrated counterfactual prediction.
Results
Antipsychotic-induced weight gain at 1 year appeared to be causally mediated by weight change during the first 12 weeks of treatment (indirect effect 5.70; 95% CI 2.83 to 8.66). At internal validation, the discrimination c-statistic for the baseline causal actionable prediction model was 0.728 (95% CI 0.661 to 0.801), and the calibration slope was 0.768 (95% CI 0.436 to 1.21). For the 12-week model, the c-statistic was 0.904 (95% CI 0.820 to 0.961), and the calibration slope was 0.601 (95% CI −0.0633 to 1.21). We used the models to predict the counterfactual outcomes of antipsychotic choice and 12-week weight change.
Conclusions
Our results show that it may be early rather than later weight change that causally mediates antipsychotic-induced weight gain at 1 year. They also demonstrate the potential for causal actionable prediction of counterfactuals for true precision medicine, although this is tempered by the feasibility scope of this study and small sample size. Our results are hypothesis-generating and not yet clinically deployable.
As organ-grinder communities in large cities like London expanded in the late nineteenth century, the question of women’s (and children’s) presence in these contexts came to the attention of middle-class observers. Several issues emerge from reports in contemporary British newspapers: Firstly, to what extent was the organ grinders’ music considered to be music? Secondly, to what extent was organ-grinding considered to be a legitimate (and not a deviant or spurious) form of work for women? Lastly, what kinds of freedoms might an organ-grinding life appear to offer, and how did this relate to contemporary middle-class movements for women’s liberation?
Climate oscillations may strongly modify continental precipitation and temperature patterns, therefore understanding their history is relevant for comprehending effects of past and ongoing climate changes. For this purpose, temperature and precipitation reconstructions beyond the instrumental record are extremely useful. As widespread terrestrial archives, loess–paleosol sequences are viable targets for such analyses. Consequently, cost-efficient geophysical proxies have gained increasing attention, but little is known about their capability to reflect even narrow climatic differences. Here we assess the sensitivity of rock-magnetic and photo-spectrometric properties of topsoil samples (n = 50) along uncorrelated, mean annual precipitation (MAP: 525±1 mm/yr to 584±1 mm/yr) and mean annual temperature (MAT: 10.8±0.1 °C to 11.2±0.1 °C) gradients across the Bačka Loess Plateau (Serbia) and test a multivariate approach. Most proxies are sensitive to MAP <565±1 mm/yr, especially anhysteretic remanent magnetization (r2 = 0.81). Applying a multivariate approach to hysteresis data reveals a robust relationship between precipitation (r2 = 0.63), aridity (r2 = 0.67) and physical properties over the entire MAP range. Although the approach needs to be further tested considering different climates, regression analyses, and timescales, our study indicates that multi-proxy approaches may increase the robustness with respect to single-proxy measurements for MAP and aridity reconstructions.
Our 2005 article in this journal provided a comprehensive synthesis and review of available literature then, and compared various aspects of organic versus conventionally produced alternatives. In this reflection, the authors provide a brief commentary on the impact of the publication and updates on the findings since it was published. We conclude with a brief commentary and outlook on selected issues relevant to organic versus conventional food products, and considerations and future directions.