During routine parasitological surveillance and monitoring activities within a National Control Programme for control of human schistosomiasis in Uganda, it was noted that cattle grazing in a water meadow immediately adjacent to Tonya primary school, where the prevalence of intestinal schistosomiasis in children was in excess of 90%, were unusually emaciated. To test the hypothesis that there may have been an anthropozoonotic focus of Schistosoma mansoni within the local herd, a young female heifer, clearly emaciated and c. 8 months old, was slaughtered from which schistosome worms were later recovered by dissection. As female worms inspected by microscopy were not gravid, morphological identification proved inconclusive but analysis of cytochome oxidase subunit I (COI) and small subunit (SSU) ribosomal DNA sequences from these worms identified them as Schistosoma bovis Sonsino, 1876. This is the first substantiated report of S. bovis from Lake Albert, western Uganda. Further epidemiological surveys are needed to clarify the extent of bovine schistosomiasis within this region, particularly so since this lakeside plain has been earmarked as a future game reserve.

This paper reports the preliminary results from three seasons of excavations in the Christian cemetery by the Tunisian-British Bulla Regia Archaeological Project. In 2017–2019, excavations in, and around, the Late Antique church in the western cemetery uncovered a complex funerary landscape with a variety of different tomb types, including mosaic caisson tombs, simple masonry tombs, amphora tombs, and earthen graves and multiple funerary mensae. The mosaics, inscriptions and finds (ceramics, glass, coins) studied in 2022 support a fourth to seventh century date for the main period of use of the cemetery.

From the seventh century AD, successive Islamic polities were established around the Mediterranean. Historians have linked these caliphates with the so-called ‘Islamic Green Revolution’—the introduction of new crops and agricultural practices that transformed the economies of regions under Muslim rule. Increasingly, archaeological studies have problematised this largely text-based model of agrarian innovation, yet much of this research remains regionally and methodologically siloed. Focusing on the Western Mediterranean, the authors offer a theoretically informed, integrated environmental archaeology approach through which to contextualise the ecological impact of the Arab-Berber conquests. Its future application will allow a fuller evaluation of the scale, range and significance of agricultural innovations during the ‘medieval millennium’.

The cemetery at Sutton Hoo in East Suffolk includes tumuli dating to the sixth–seventh centuries ad. The largest contained an intact ship-burial. The man commemorated is not identifiable, but is often presumed to be Rædwald, rex Anglorum c ad599–624/5. Excavation was curtailed by the outbreak of war in 1939. Despite subsequent re-excavation and lengthy research, questions remain.

Information dispersed in the definitive publication is correlated and developed. Digital 3D imaging of the ship’s iron fastenings are used here to extrapolate curved lines of missing rivets and superimpose them on the burial chamber plan. A digital roof reconstruction is also presented.

Mechanisms of collapse of the objects are deduced from their positioning and damage, revealing space for access to the chamber. A cross-section depicts the calculated height of the deck and known tilt of the ship. Residues of phosphate, Middle Eastern bitumen, tar and tape cumulatively suggest embalming practices. A temporary coffin and a bed on which possessions were placed are proposed.

The most valuable object relinquished is deduced to be the ship. Fragments of a possible anchor are identified. The suggested identification of the iron stand as a raised light would allow supporting ships to follow.

Six drug regulatory reviewers and 11 pharmaceutical industry scientists were interviewed to explore their perspectives on the obstacles and opportunities for greater implementation of the Three Rs (replacement, reduction, refinement) in drug research and development. Participants generally supported the current level of animal use in the pharmaceutical industry and viewed in vitro methods as supporting, but not replacing, the use of animals. Obstacles to greater use of the Three Rs cited by participants included the lack of non-animal alternatives; requirements for statistical validity; reluctance by industry and regulators to depart from established patterns of animal use; the priority of commercial objectives ahead of the Three Rs; and concern that less animal testing could jeopardise human safety. Opportunities identified for the Three Rs included the development of better animal models including genetically modified (GM) animals; pursuit of more basic knowledge, notably drug action on gene expression; re-use of animals; greater use of pilot studies; using sufficient numbers of animals per test to avoid repeating inconclusive studies; regular review of animal data in regulatory requirements; and following the regulatory option of combining segments of reproductive toxicology studies into one study. In some areas, greater implementation of the Three Rs seemed well aligned with industry priorities, for example, phenotypic characterisation of GM animals and validation of alternative methods. In other areas, wider use of the Three Rs may require building consensus on areas of disagreement including the usefulness of death as an endpoint; the suitability of re-using animals; and whether GM animals and the use of pilot studies contribute to reduction.

The allocation of any benefit that arises from worker-generated innovation is complicated by the importance of three separate areas of law — employment law, intellectual property law and equity — and the distinction between those types of innovation that attract intellectual property rights and those types that do not (the latter being a category that is often referred to as ‘know-how’). The purpose of this article is to engage with the legal scholarship on the principles that are relevant to innovation. To date, the discussion has focused on two distinct approaches — what may be termed the economic and the fairness perspectives. The former may be seen as a justification for the current regime, while the latter has focused on the perceived needs of workers (in large part in opposition to the employers). Our argument is that these two approaches are both incomplete. In an attempt to get closer to a workable framework for the effective allocation of benefits, we offer a third approach; one that is based on the practices that are central to the employer-worker relationship.

Severity classification systems (ie pain scales, categories of invasiveness, degrees of severity etc) are used to classify the adverse effects experienced by animals used for scientific purposes. Currently, eleven countries use severity classification systems. These systems have developed in various ways, depending on each country's process for overseeing the use of animals in science, as well as the particular aspects emphasised by those individuals who have championed their implementation. Severity classification serves four main purposes: as a tool to assist animal ethics committees in ethical review; education of animal users about concepts for humane animal experimentation; provision of data to inform the public about scientific animal use; and provision of data to inform national policies. At a time when the newly accepted European Union Directive will make the reporting of severity data mandatory, we review the characteristics of international severity classification systems and how they have evolved; analyse the effectiveness of some systems; and identify emerging challenges for severity classification.

The Work Choices package of legislative reforms has significantly altered both the institutions and the instruments of the federal regulatory architecture for setting minimum working conditions. This paper surveys the reduced role of awards and of the Australian Industrial Relations Commission, before considering the function and content of the Australian Fair Pay and Conditions Standard and Australian Pay and Classification Scales, as well as the role of the newly created Australian Fair Pay Commission. It argues that the Work Choices reforms have shifted power over the setting of minimum working conditions to the government, which will set many conditions directly, and to employers, who will be entitled to require employees to be party to workplace agreements that displace very many of the minimum working conditions that are otherwise purportedly guaranteed. These shifts have opened up the space for significant reductions in minimum working conditions, as well as for falls in real wages for those not able to benefit from wage bargaining.

Recent scholarship on North African cities has done much to dispel earlier assumptions about late antique collapse and demonstrate significant continuity into the Byzantine and medieval periods. Yet urban changes did not affect North Africa evenly. Far less is known about the differing regional trajectories that shaped urban transformation and the extent to which pre-Roman and Roman micro-regions continued to share meaningful characteristics in subsequent periods. This article provides a preliminary exploration of regional change from the fourth to the eleventh century focused on a zone in the Central Medjerda Valley (Tunisia) containing the well-known sites of Bulla Regia and Chimtou. We place these towns in their wider historical and geographical setting and interrogate urban change by looking at investment in public buildings and spaces, religious buildings and housing, and ceramic networks. The process of comparison identifies new commonalities (and differences) between the sites of this stretch of the Medjerda River and provides a framework for understanding the many transformations of North African cities over the long late antiquity.