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Background: In March–April 2021, 23 patients at a 906-bed hospital in Delaware had surgical implantation of a bone graft product contaminated with Mycobacterium tuberculosis; 17 patients were rehospitalized for surgical site infections and 6 developed pulmonary tuberculosis. In May 2021, we investigated this tuberculosis outbreak and conducted a large, multidisciplinary, contact investigation among healthcare personnel (HCP) and patients potentially exposed over an extended period in multiple departments. Methods: Exposed HCP were those identified by their managers as present, without the use of airborne precautions, in operating rooms (ORs) during index spine surgeries or subsequent procedures, the postanesthesia care unit (PACU) when patients had draining wounds, inpatient rooms when wound care was performed, and the sterile processing department (SPD) on the days repeated surgeries were performed. We created and assigned an online education module and symptom screening questionnaire to exposed HCP. Employee health services (EHS) instituted a dedicated phlebotomy station to provide interferon-γ release assay (IGRA) testing for HCP at ≥8 weeks after last known exposure. EHS managed all exposed HCP, including nonemployees (eg, private surgeons) via automated e-mail reminders, which were escalated through supervisory chains as needed until follow-up completion. The infection prevention team notified exposed patients, defined as those who shared semiprivate rooms with case patients with transmissible tuberculosis. The Delaware Division of Public Health performed IGRA testing. Results: There were 506 exposed HCP in ORs (n = 100), the PACU (n = 87), inpatient units (n = 140), the SPD (n = 54), and other locations (n = 122); 83% were employed by the health system. Surgical masks and eye protection were routinely used during patient care. All exposed HCP completed screening by December 17, 2021. Furthermore, 2 HCP had positive IGRAs without symptoms or chest radiograph abnormalities, indicating latent tuberculosis infection, but after further review of records and interviews, we discovered that they had previously tested positive and had been treated for latent tuberculosis infection. In addition, 5 exposed patients tested negative and 2 remain pending. Conclusions: This large investigation demonstrated the need for a systematic process that encompassed all exposed HCP including nonemployees and incorporated administrative controls to ensure complete follow-up. We did not identify any conversions related to this outbreak despite high burden of disease in case patients and multiple exposures to contaminated bone-graft material and infectious bodily fluids without respirator use. Transmission risk was likely reduced by baseline surgical mask use and rapid institution of airborne precautions after outbreak recognition.
The Japanese Association for Disaster Medicine (JADM) Disaster Medical Coordination Support Team (DMCST) was formed in 2016 when Japan experienced Kumamoto earthquake to support other disaster medical assistance teams in terms of headquarter operation logistics.
Aim:
Introducing medical association-based disaster medical support team.
Methods:
JADM DMCST was formed by an association member who had experience in disaster medical headquarter operation and logistic support. Disaster medical headquarter tends to have a gap between acute phase and sub-acute phase due to an alternation of disaster medical assistance team. To keep disaster medical management at medical management headquarter, experienced manpower requires. JADM DMCST provided assistance to fill those gaps.
Results:
For 2016 Kumamoto Earthquake, 107 members responded as a JADM DMCST, 78 members responded for 2018 West Japan Torrential Rain Disaster. Most of the members responded to the medical headquarter of affected prefecture’s, city’s, and medical region’s headquarters. Members provided logistic support in headquarter operation, gathered medical needs information, helped medical team dispatch coordination, gathered evacuation shelter information, provided heat stroke support for evacuees, assisted deep vein thrombosis management, provided AED delivery operation, and helped statistical information analysis based on WHO standards.
Discussion:
JAMD DMCST could provide medical management support at each headquarters without time span restrictions which the most of disaster medical assistance team has. Since all members were experienced in disaster medical management, they could connect and keep providing medical assistance to the affected people. At the time of disaster, disaster medical management headquarter is always short handed due to a large amount of incoming information. All this information was managed by the support team. Although JADM DMCST contributed to support headquarter management, each member had to pay for his/her transportation, hotel, food and any devices required for headquarter operations. Therefore, improving member’s responding condition is next problem to solve.
On March 11, 2011, the Great East Japan Earthquake struck the northeastern coast of Japan with the magnitude nine. Ishinomaki medical zone was affected most severely with 328 evacuation shelters and approximately 50,000 evacuees. The Ishinomaki Zone Joint Relief Team gathered information directly from all evacuation shelters using assessment sheets. Based on this assessment data, various measures were carried out for environmental improvement of the shelters. To prepare for the next major disaster, a software program called Rapid Assessment System of Evacuation Center Condition - Gonryo and Miyagi (RASECC-GM) was developed, which computerizes the whole process, including entering, tabulating, and managing of shelter assessment data.
Aim:
To verify the feasibility, usability, and accuracy of RASECC-GM, a verification test was performed using mock shelter data on October 23-26, 2018, to coincide with Logistics Training Course of Medical Logistics for Disasters held by Iwate Medical University.
Methods:
On October 22, 2018 at four simulated disaster relief and health care branches, participants at each branch were asked to enter two mock shelter data items, submit a closed shelter request, and register a new shelter using RASECC-GM, respectively. The next day participants were asked to enter two mock shelter data items per branch while offline and upload the data to the server when next online. The uploaded data was checked for accuracy and whether it could be viewed on the management screen. After the test, a questionnaire survey was given to participants to verify the feasibility and usability of RASECC-GM.
Results:
It was confirmed that RASECC-GM functioned almost correctly. All participants answered that input operation was easy to understand, and 90.9% of participants could input without a mistake and did not feel stress when inputting data.
Discussion:
RASECC-GM appeared to be useful to shelter assessment, but further improvements are needed for practical use.
Electronic structures of single crystal pentacene are of great interest for the elucidation of charge carrier transport in organic semiconductor materials. Experimental observation of valence band dispersion was recently achieved on single crystal samples of pentacene; however, its intrinsic properties are still unresolved because past experiments were performed on specimens with surface oxides formed by exposure to the ambient atmosphere. In this work, X-ray photoelectron spectroscopy (XPS) and angle-resolved ultraviolet photoelectron spectroscopy (ARUPS) were conducted on single-crystal pentacene samples prepared without ambient exposure. The XPS results confirmed the reduction of the abundance of oxide impurities on the present samples. The ARUPS measurements clearly resolved the valence band structures of the single-crystal pentacene in four symmetry directions of the surface Brillouin zone, indicating anisotropy of at least a factor of 2.4 for the intermolecular transfer integral and hole effective mass at the valence band maximum.
There is considerable diversity of population trends across low- and middle-income countries and not all have reached the final stage of demographic transition. Despite this, population ageing is accelerating in almost all countries, particularly in middle-income emerging economies. The speed of demographic change poses significant policy challenges for these countries, and they have limited time to set in place the necessary institutions (Lloyd-Sherlock, 2010). Building a knowledge base capable of supporting effective policies addressing rapid population ageing in such contexts is urgent. This chapter reports on the design and main findings of the research project Ageing, Well-Being and Development: A Comparative Study of Brazil and South Africa.
The research focuses on the wellbeing of older people and their households. For all countries, successfully meeting the challenges of population ageing involves ensuring that older populations enjoy adequate levels of wellbeing. For countries like Brazil and South Africa, the main challenge is to ensure that older people, and public policy that targets them, are fully integrated into economic and social development. A key hypothesis guiding the research project was that ageing, wellbeing and development are closely interlinked.
• The research aimed to provide answers to the following questions:
• What are the main effects of individual ageing on the dynamics of household income and livelihoods in Brazil and South Africa?
• What are the effects of individual ageing on household dynamics?
• With the benefit of cross-country comparisons, which are the institutions and social structures that could best support ‘active ageing’ in developing countries?
• What is the impact of pension entitlements and other anti-poverty programmes on the wellbeing of older people and their households?
This research examined the impact of individual ageing on the wellbeing of older people and their households in low-income areas Brazil and South Africa, with a view to informing appropriate policies to address the challenges of accelerated population ageing in developing countries. The main source of information for this study was a longitudinal and comparative survey of older persons and their households in South Africa and Brazil constructed as part of the project. Building on an earlier study in the two countries undertaken in 2001-03, we collected a second round of survey data by visiting the same households in 2008/09.
In 2015, the authors reported the results of a preliminary investigation of preventable disaster deaths (PDDs) at medical institutions in areas affected by the Great East Japan Earthquake (2011). This initial survey considered only disaster base hospitals (DBHs) and hospitals that had experienced at least 20 patient deaths in Miyagi Prefecture (Japan); therefore, hospitals that experienced fewer than 20 patient deaths were not investigated. This was an additional study to the previous survey to better reflect PDD at hospitals across the entire prefecture.
Method
Of the 147 hospitals in Miyagi Prefecture, the 14 DBHs and 82 non-DBHs that agreed to participate were included in an on-site survey. A database was created based on the medical records of 1,243 patient deaths that occurred between March 11, 2011 and April 1, 2011, followed by determination of their status as PDDs.
Results
A total of 125 cases of PDD were identified among the patients surveyed. The rate of PDD was significantly higher at coastal hospitals than inland hospitals (17.3% versus 6.3%; P<.001). Preventable disaster deaths in non-DBHs were most numerous in facilities with few general beds, especially among patients hospitalized before the disaster in hospitals with fewer than 100 beds. Categorized by area, the most frequent causes of PDD were: insufficient medical resources, disrupted lifelines, delayed medical intervention, and deteriorated environmental conditions in homes and emergency shelters in coastal areas; and were delayed medical intervention and disrupted lifelines in inland areas. Categorized by hospital function, the most frequent causes were: delayed medical intervention, deteriorated environmental conditions in homes and emergency shelters, and insufficient medical resources at DBHs; while those at non-DBHs were disrupted lifelines, insufficient medical resources, delayed medical intervention, and lack of capacity for transport within the area.
Conclusion:
Preventable disaster death at medical institutions in areas affected by the Great East Japan Earthquake occurred mainly at coastal hospitals with insufficient medical resources, disrupted lifelines, delayed medical intervention, and deteriorated environmental conditions in homes and emergency shelters constituting the main contributing factors. Preventing PDD, in addition to strengthening organizational support and functional enhancement of DBHs, calls for the development of business continuity plans (BCPs) for medical facilities in directly affected areas, including non-DBHs.
YamanouchiS, SasakiH, KondoH, MaseT, OtomoY, KoidoY, KushimotoS. Survey of Preventable Disaster Deaths at Medical Institutions in Areas Affected by the Great East Japan Earthquake: Retrospective Survey of Medical Institutions in Miyagi Prefecture. Prehosp Disaster Med. 2017;32(5):515–522.
Field data from Stillberg (Switzerland), provided by SFISAR, have been analysed in order to understand the spatial distribution of snow transported by wind in avalanche-starting zones. The results have been used to develop a new empirical model for snowdrift distribution. This model constitutes the “snow-wind module” of the knowledge-based computer system called ELSA.
The model is based on an empirical parameter called the wind or “aeolien” coefficient. It represents the relation between two snow heights at a given place: the snow accumulated at the end of a wind period (or wind episode) and the snow available for transport at the beginning of the wind period. The wind coefficient has been established using field data from the Stillberg site.
In experimental snowdrifting mass-flux measurements many different instruments have been tested (Takeuchi, CEMAGREE Mases, etc.). Very often the results obtained are a function of the gauge used. However, in order to compare data from different instruments, orders of magnitude have to be similar.
Since 1992, snowdrifting has been studied at an experimental plot at La Molina ski resort (eastern Spanish Pyrenees). The alpine site, characterized by a plateau topography, is located at 2250 m.
In this paper, different gauges used to measure snowdrifting mass flux at this site are presented: one snow-collector column and two types of snow traps. Snow-collector columns (prismatic boxes) are permanent installations and are used to measure the mass-flux episode. Snow traps (Takeuchi, 1980: modified) are lighter and more mobile, and they are used for short experiments during a wind episode during which mass-flux data are obtained.
The three different gauges are compared and the rate of trapping efficiency is suggested from a comparison of the field data with estimated mass-flux data deduced from empirical formulae (Mellor and Fellers, 1986; Naaim-Bouvet and others, 1996). The mass-flux values obtained at the experimental site are lower than the estimated values.
Snowdrift formation has been monitored in the eastern Spanish Pyrenees since 1992 at an experimental study plot at the La Molina ski resort between 2000 and 2400 m. Several instruments were installed to characterize the wind, quantify snow-mass flux, detect snowdnfting episodes and measure the evolution of a natural snowdrift.
This plot is situated within a natural snowdrift and is equipped with measuring instruments such as snow poles, three columns of snow collectors (prismatic boxes) facing the dominant winds and an anemographic station.
During the 4 years of data acquisition, the thickness of the snowdrift has been measured and the snow collectors checked once each week. An active interest has been taken in the relationship between snowdrift development and drifting snow during a wind episode.
The relationship observed between wind, drifting snow and the development of the snowdrift is presented The results show: (1) the amount of snow collected in the snow collectors is related to wind intensity and to the availability and the quality of drifting snow, and (2) wind intensity principally affects the relative location of maximum snowdrift growth rather than controlling the thickness of the snowdrift.
By comparing the evolution of the snowdrift with Tabler’s (1975) model, we observed that it fits with the topographic features of our study area for the three seasons shown.
Achieving high healthcare personnel (HCP) influenza vaccination rates has typically required mandating vaccination, which is often challenging to implement. Our objective was to achieve >90% employee influenza vaccination without a mandate.
DESIGN
Prospective quality improvement initiative
SETTING AND PARTICIPANTS
All employees of a 2-hospital, 1,100-bed, community-based academic healthcare system.
METHODS
The multimodal HCP vaccination campaign consisted of a mandatory declination policy, mask-wearing for non-vaccinated HCP, highly visible “I’m vaccinated” hanging badges, improved vaccination tracking, weekly compliance reports to managers and vice presidents, disciplinary measures for noncompliant HCP, vaccination stations at facility entrances, and inclusion of a target employee vaccination rate (>75%) metric in the annual employee bonus program. The campaign was implemented in the 2011–2012 influenza season and continued throughout the 2012–2013 through 2014–2015 influenza seasons. Employee compliance, vaccination, exemption and declination rates were calculated and compared with those of the seasons prior to the intervention.
RESULTS
Compared with vaccination rates of 57%–72% in the 3 years preceding the intervention, employee influenza vaccination increased to 92% in year 1 and 93% in years 2–4 (P<.001). The proportion of employees declaring medical/religious exemptions or declining vaccination decreased during the 4 years of the program (respectively, 1.2% to 0.5%, P<.001; 4.4% to 3.8%, P=.001).
CONCLUSIONS
An integrated multimodal approach incorporating peer pressure, accountability, and financial incentives was associated with increased employee vaccination rate from ≤72% to ≥92%, which has been sustained for 4 influenza seasons. Such programs may provide a model for behavioral change within healthcare organizations.
We investigated electronic structure of one-dimensional biradical molecular chain which is constructed by exploiting the covalency between organic molecules of a diphenyl derivative of s-indacenodiphenalene (Ph2-IDPL). To control the crystallinity, we used gas deposition method. Ultraviolet photoelectron spectroscopy (UPS) revealed developed band structure with wide dispersion of the one-dimensional biradical molecular chain.
Development studies offers a specific set of perspectives on poverty, deprivation and welfare, which take particular account of conditions of generalised scarcity, limited access to salaried labour and weak formal sector institutions (Gough and Wood, 2004). While a great deal of the literature about development focuses on resources and resource deficits, the relational dimensions of development and underdevelopment are increasingly under the spotlight. New theoretical frameworks, such as Amartya Sen's (1999) work on capabilities, functionings and entitlements, discussed in more detail in Chapter Five, have found fertile ways of combining attention on resources and relations. These, more comprehensive, approaches demonstrate that poverty and deprivation cannot be reduced to deficits in material resources alone, but must also take account of other dimensions of social exclusion. While these approaches have generated some valuable insights, they have rarely been applied specifically to older people (Lloyd-Sherlock, 2002). This chapter aims to contribute to this emerging literature by examining the role of material resources and social relations in shaping the social inclusion and exclusion of older people in Latin America and South Africa.
The multifaceted nature of poverty and exclusion, and the diverse range of social and economic conditions in developing countries, suggest the need to set the boundaries of this chapter's discussion with care. Our focus is on two dimensions of social exclusion that affect people in later life: access to financial security and pensions; and older people's perceptions of inclusion and the quality of their social relationships. While the former provides insights into the material resources domain of social exclusion, the latter highlights relational dimensions of the exclusion construct (Scharf et al, 2005).
In exploring issues relating to perceived social relations and financial security in two middle-income countries, Brazil and South Africa, we are able to take advantage of a unique data set. Our analysis draws on a survey of around 1000 households with older people in Brazil and South Africa, conducted in 2008/09 as part of a research project on ‘Ageing, well-being and development’. In addition to the survey, a qualitative component involved in-depth interviews with people living in households that were also part of the household survey. The project’s main aim has been to explore the well-being of older people and their households in the two countries.
The paper provides an account of an innovative collaborative work between composer/violinist Elo Masing, choreographer/dancer Jean Lee, and the Kreutzer String Quartet. The project challenges the conventions of music and dance collaboration by proposing a fundamentally new way of working across disciplines, establishing a profound interrelation between movement and sound production.
The work so far has mostly involved developing a new notation system for string instruments and dancer suitable for recording the sounds and movements the work in progress will primarily be based on. The paper will, at this stage, demonstrate only a fraction of the various possibilities of this new way of musician–dancer collaboration that is estimated to span over the next couple of years. The idea for the piece dates back to June 2010, when a structured improvisation was created in collaboration between Elo Masing and Jean Lee, commissioned for a conference at Roehampton University.
The innovative aspect of the project is manifested in the development of choreography and music together from the very beginning, using new sound and movement languages discovered in interdisciplinary improvisation sessions. In the center of the collaboration lies the definition of the roles of the musician and the dancer as equal, with equally complex compositional material and interchanging ideas. That means composing music and dance simultaneously and letting them influence each other.
The new notation system for string instruments focuses on the movements of string players, thus creating a possibility for relating music to dance in a more tangible and visual rather than conceptual and abstract way.
In 3D packaging, Through Silicon Vias (TSVs) with high aspect ratios and depths measuring tens of microns are filled by advanced Cu electroplating processes. Today's 300mm TSV plating platforms are intended to produce bottom-up via fill, no seam voids, and minimal, controlled overburden. To achieve this, the preceding Cu-seed coverage must be continuous at a constant resistance, and the plating chemistries optimized. However, other factors such as hardware configurations and simple depletion of the plating formulations during the extended TSV process can lead to high Cu overburden thickness requiring a high removal rate (HRR) chemical-mechanical polish (CMP) process to remove the thick Cu layer.
Presented here are CMP results of a thick Cu overburden (~6um) resulting from the fill of 5 x 25um TSVs on 300mm wafers. The goal is to uniformly polish the overburden and utilize the tool's endpoint system at Cu clear before the next step of conventional barrier CMP. Slurries were screened for removal rate, uniformity, planarization ability, and defectivity. This study focuses on achieving a removal rate of >2.5um/min through evaluation of several commercial slurries in a multi-step polish application. Cross-sections post-plating show the Cu overburden, barrier and liner layer. Cross-sections post-CMP quantify Cu recess, dielectric loss, and presence/absence of seam defects. The process selected is demonstrated to achieve good planarization results with low occurrence of polish defects, at a rate and selectivity suitable for emerging 3D TSV Cu CMP applications.
3D interconnect wafer-to-wafer or die-to-wafer integration requires a wafer thinning operation to expose copper (Cu)-filled through-silicon vias (TSVs) from the backside of the wafer. The wafer thinning flow uses edge trim, backgrind, backpolish, and chemical mechanical polishing (CMP). This paper presents an overview of the wafer grinding process. We have demonstrated the capability to edge-trim and backgrind 300 mm TSV and non-TSV wafers down to 30 microns (μm) while bonded to a handle wafer. TSV wafers were further processed on a CMP tool to remove the last few microns of Si, exposing the Cu-filled TSVs. Metrology techniques were used to inspect and measure the wafer edge trim and final thinned wafer thickness. The quality of the thinned wafer was characterized by atomic force microscopy (AFM) to observe surface roughness and by transmission electron microscopy (TEM) to quantify crystalline damage below the surface of the thinned wafer. Further characterization included measuring wafer thickness, total thickness variation (TTV), bow, and warp. Exposed TSVs were characterized by laser microscope to measure the height of Cu protrusions. These critical elements of a manufacturing-worthy 300 mm wafer thinning process for 3D are discussed.
Titanium and cobalt silicides have long been used as gate electrode materials for very large-scale integrations (VLSI) circuits. As scaling has pushed the industry to quarter micron technologies and below, cobalt has become the material of choice for forming silicides, since it can maintain its low resistivity on much narrower line widths. Oxidation of the cobalt film is a concern during silicide processing, as the cobalt oxide will not be removed during the cobalt etch step. To protect against the oxidation of the cobalt layer during the silicidation process, the reaction is conducted underneath a titanium nitride (TiN) capping layer. Variations in the TiN capping layer thickness were investigated to determine the affect on oxygen sensitivity of the cobalt silicide process. A strong correlation was found to the thickness of the TiN-capping layer, to the oxygen concentration required to oxidize cobalt during the silicidation process.