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Delve into the ideal resource for theory and research on parental monitoring and adolescents' disclosure to and concealment from parents. This handbook presents ground-breaking research exploring how adolescents respond to parents' attempts to control and manage their activities and feelings. The chapters highlight how adolescents' responses are as important for their mental health and behavior as parents' attempts to regulate them. Examining responsive, intrusive, and invasive parenting behaviors, the volume addresses modern challenges like monitoring in the digital age and medical decision-making. It covers cutting-edge research on diverse cultures and groups including Latinx, Turkish, Chinese, LGBTQ+, and chronically ill youth. The internationally recognized contributors offer insights from different theoretical perspectives and describe novel methodological approaches, focusing on variations across different developmental stages, contexts, and cultures.
Operationalizing multi-site Community Engagement (CE) Studios to inform a research program is valuable for researchers. We describe the process and outcomes of hosting three CE Studios with Community Experts aged 65 years or older with chronic conditions and care partners of older adults. Experts gave feedback about processes for testing the feasibility, efficacy, effectiveness, and implementation of audio recording clinic visits and sharing recordings with patients who have multimorbidity and their care partners.
Methods:
The CE Cores of the Clinical and Translational Science Awards Programs at three academic health science centers created a joint CE Studio guide. Studios were conducted iteratively by site. Following receipt of the final reports, responses were compared to find themes, similarities, and differences on four topics in addition to overall commentary: Recruitment and Retention, Study Protocol, Study Reminders and Frequency, and Recording Technology.
Results:
Eighteen older adults and care partners in three states provided valuable feedback to inform multi-site trials. Feedback influenced multiple aspects of trials in process or subsequently funded. Experts provided critique on the wording of study invitations, information sheets, and reminders to engage in study procedures. Experts were concerned for participants being disappointed by randomization to a control arm and advised how investigators should prepare to address that.
Conclusions:
Multi-site CE Studios should be consecutive, so each team can learn from the previous teams. Using the CES Toolkit ensures that final reports were easily comparable and utilized to develop a research program that now includes three federally funded clinical trials.
White matter hyperintensity (WMH) burden is greater, has a frontal-temporal distribution, and is associated with proxies of exposure to repetitive head impacts (RHI) in former American football players. These findings suggest that in the context of RHI, WMH might have unique etiologies that extend beyond those of vascular risk factors and normal aging processes. The objective of this study was to evaluate the correlates of WMH in former elite American football players. We examined markers of amyloid, tau, neurodegeneration, inflammation, axonal injury, and vascular health and their relationships to WMH. A group of age-matched asymptomatic men without a history of RHI was included to determine the specificity of the relationships observed in the former football players.
Participants and Methods:
240 male participants aged 45-74 (60 unexposed asymptomatic men, 60 male former college football players, 120 male former professional football players) underwent semi-structured clinical interviews, magnetic resonance imaging (structural T1, T2 FLAIR, and diffusion tensor imaging), and lumbar puncture to collect cerebrospinal fluid (CSF) biomarkers as part of the DIAGNOSE CTE Research Project. Total WMH lesion volumes (TLV) were estimated using the Lesion Prediction Algorithm from the Lesion Segmentation Toolbox. Structural equation modeling, using Full-Information Maximum Likelihood (FIML) to account for missing values, examined the associations between log-TLV and the following variables: total cortical thickness, whole-brain average fractional anisotropy (FA), CSF amyloid ß42, CSF p-tau181, CSF sTREM2 (a marker of microglial activation), CSF neurofilament light (NfL), and the modified Framingham stroke risk profile (rFSRP). Covariates included age, race, education, APOE z4 carrier status, and evaluation site. Bootstrapped 95% confidence intervals assessed statistical significance. Models were performed separately for football players (college and professional players pooled; n=180) and the unexposed men (n=60). Due to differences in sample size, estimates were compared and were considered different if the percent change in the estimates exceeded 10%.
Results:
In the former football players (mean age=57.2, 34% Black, 29% APOE e4 carrier), reduced cortical thickness (B=-0.25, 95% CI [0.45, -0.08]), lower average FA (B=-0.27, 95% CI [-0.41, -.12]), higher p-tau181 (B=0.17, 95% CI [0.02, 0.43]), and higher rFSRP score (B=0.27, 95% CI [0.08, 0.42]) were associated with greater log-TLV. Compared to the unexposed men, substantial differences in estimates were observed for rFSRP (Bcontrol=0.02, Bfootball=0.27, 994% difference), average FA (Bcontrol=-0.03, Bfootball=-0.27, 802% difference), and p-tau181 (Bcontrol=-0.31, Bfootball=0.17, -155% difference). In the former football players, rFSRP showed a stronger positive association and average FA showed a stronger negative association with WMH compared to unexposed men. The effect of WMH on cortical thickness was similar between the two groups (Bcontrol=-0.27, Bfootball=-0.25, 7% difference).
Conclusions:
These results suggest that the risk factor and biological correlates of WMH differ between former American football players and asymptomatic individuals unexposed to RHI. In addition to vascular risk factors, white matter integrity on DTI showed a stronger relationship with WMH burden in the former football players. FLAIR WMH serves as a promising measure to further investigate the late multifactorial pathologies of RHI.
Laser-directed energy deposition (L-DED) is a key enabling technology for the repair of high-value aerospace components, as damaged regions can be removed and replaced with additively deposited material. While L-DED repair improves strength and fatigue performance compared to conventional subtractive techniques, mechanical performance can be limited by process-related defects. To assess the role of oxygen on defect formation, local and chamber-based shielding methods were applied in the repair of 300M high strength steel. Oxidation between layers for locally shielded specimens is confirmed to cause large gas pores which have deleterious effects on fatigue life. Such pores are eliminated for chamber shielded specimens, resulting in an increased ductility of ∼15%, compared to ∼11% with chamber shielding. Despite this, unmelted powder defects are not affected by oxygen content and are found in both chamber- and locally shielded samples, which still have negative consequences for fatigue.
The socioeconomics of the Anthropocene is exposing coastal regions to multiple pressures, including climate change hazards, resource degradation, urban development and inequality. Tourism is often raised as either a panacea to, or exacerbator of, such threats to ecosystems and sustainable livelihoods. To better understand the impacts of tourism on coastal areas, Scopus and Web of Science databases were searched for the top 100 cited papers on coastal tourism. Web of Science suggested ‘highly cited’ papers were also included to allow for more recent high-impact papers. Of the papers retrieved, 44 focused on the impacts of tourism. Social/cultural and environmental impacts were viewed as mostly negative, while economic impacts were viewed as mostly positive but only of actual benefit to a few. In addition, when compared with recent whole-of-sector reviews and reports it was evident that coastal tourism is increasingly a global enterprise dominated by large corporations that leverage various interests across local to transnational scales. Through this global enterprise, even the positive economic benefits identified were overshadowed by a broader system of land and property development fuelling local wealth inequity and furthering the interests of offshore beneficiaries. Only two highly cited papers discussed tourism within a broader context of integrated coastal zone management, suggesting that tourism is mostly assessed as a discrete sector within the coastal zone and peripheral to other coastal management considerations or the global tourism sector as a whole. The findings have relevance to the holistic management of coasts, coastal tourism and the achievement of sustainable development goals in a way that considers the increasing threats from coastal hazards, resource extraction and urbanisation, as well as the pervasive impacts of international business systems from local to global scales.
The first demonstration of laser action in ruby was made in 1960 by T. H. Maiman of Hughes Research Laboratories, USA. Many laboratories worldwide began the search for lasers using different materials, operating at different wavelengths. In the UK, academia, industry and the central laboratories took up the challenge from the earliest days to develop these systems for a broad range of applications. This historical review looks at the contribution the UK has made to the advancement of the technology, the development of systems and components and their exploitation over the last 60 years.
This work investigated the photophysical pathways for light absorption, charge generation, and charge separation in donor–acceptor nanoparticle blends of poly(3-hexylthiophene) and indene-C60-bisadduct. Optical modeling combined with steady-state and time-resolved optoelectronic characterization revealed that the nanoparticle blends experience a photocurrent limited to 60% of a bulk solution mixture. This discrepancy resulted from imperfect free charge generation inside the nanoparticles. High-resolution transmission electron microscopy and chemically resolved X-ray mapping showed that enhanced miscibility of materials did improve the donor–acceptor blending at the center of the nanoparticles; however, a residual shell of almost pure donor still restricted energy generation from these nanoparticles.
We describe system verification tests and early science results from the pulsar processor (PTUSE) developed for the newly commissioned 64-dish SARAO MeerKAT radio telescope in South Africa. MeerKAT is a high-gain (${\sim}2.8\,\mbox{K Jy}^{-1}$) low-system temperature (${\sim}18\,\mbox{K at }20\,\mbox{cm}$) radio array that currently operates at 580–1 670 MHz and can produce tied-array beams suitable for pulsar observations. This paper presents results from the MeerTime Large Survey Project and commissioning tests with PTUSE. Highlights include observations of the double pulsar $\mbox{J}0737{-}3039\mbox{A}$, pulse profiles from 34 millisecond pulsars (MSPs) from a single 2.5-h observation of the Globular cluster Terzan 5, the rotation measure of Ter5O, a 420-sigma giant pulse from the Large Magellanic Cloud pulsar PSR $\mbox{J}0540{-}6919$, and nulling identified in the slow pulsar PSR J0633–2015. One of the key design specifications for MeerKAT was absolute timing errors of less than 5 ns using their novel precise time system. Our timing of two bright MSPs confirm that MeerKAT delivers exceptional timing. PSR $\mbox{J}2241{-}5236$ exhibits a jitter limit of $<4\,\mbox{ns h}^{-1}$ whilst timing of PSR $\mbox{J}1909{-}3744$ over almost 11 months yields an rms residual of 66 ns with only 4 min integrations. Our results confirm that the MeerKAT is an exceptional pulsar telescope. The array can be split into four separate sub-arrays to time over 1 000 pulsars per day and the future deployment of S-band (1 750–3 500 MHz) receivers will further enhance its capabilities.
An Eclipse is an astronomical event that convenes a large audience. Few days before it, most of the community is aware of the event and the press is activated fully on it. The alignment recovers our most intrinsic human aspects, the curiosity, and enthusiasm for a natural phenomenon. This work is focused to enjoy and perceive it in three different ways: visually, listening, and in an artistic expression.
We focused on the construction of more than one hundred LightSound devices, which the main purpose is to record the light intensity and transform it into different tones. Besides, we created an artistic representation of the Eclipse motivated by the ancestral culture of the people residing in the totality zone. This music adds a sensorial joy to the eclipse event.