C-type lectins (CTLs), a diverse family of pattern recognition receptors, are essential for immune recognition and pathogen clearance in invertebrates. TcCTL17 contains one carbohydrate recognition domain and three scavenger receptor Cys-rich domains. Spatial and temporal expression analysis revealed that TcCTL17 is highly expressed in early pupa, early adult stages, and the larval gut at 20 days. The recombinant TcCTL17 exhibited dose-dependent binding to lipopolysaccharides and peptidoglycans, Ca2+-dependent binding and agglutination of bacteria in vitro. Knocking down TcCTL17 before bacterial exposure reduced survival rates and increased bacterial loads in T. castaneum larvae, accompanied by decreased antimicrobial peptide expression and haemolymph phenoloxidase activity. Additionally, TcCTL17 RNA interference caused developmental abnormalities, affecting metamorphosis and fecundity, possibly by influencing the 20E, JH, and vitellogenin pathways. These findings underscore dual functions of TcCTL17 in immunity and development, making it a potential target for pest management.

Currently, workers in sand casting face harsh environments and the operation safety is poor. Existing pouring robots have insufficient stability and load-bearing capacity and cannot perform intelligent pouring according to the demand of pouring process. In this paper, a hybrid pouring robot is proposed to solve these limitations, and a vision-based hardware-in-the-loop (HIL) control technology is designed to achieve the real-time control problems of simulated pouring and pouring process. Firstly, based on the pouring mechanism and the motion demand of ladle, a hybrid pouring robot with a 2UPR-2RPU parallel mechanism as the main body is designed. And the equivalent hybrid kinematic model was established by using Eulerian method and differential motion. Subsequently, a motion control strategy based on HIL simulation technique was designed and presented. The working space of the robot was obtained through simulation experiments to meet the usage requirements. And the stability of the robot was tested through the key motion parameters of the robot joints. Based on the analysis of pouring quality and trajectory, optimal dynamic parameters for the experimental prototype are obtained through water simulation experiments, the pouring liquid height area is 35–40 cm, the average flow rate of pouring liquid is 112 cm3/s, and the ladle tilting speed is 0.0182 rad/s. Experimental results validate the reasonableness of the designed pouring robot structure. Its control system realizes the coordinated movement of each branch chain to complete the pouring tasks with different variable parameters. Consequently, the designed pouring robot will significantly enhance the automation level of the casting industry.

Whether assisted hatching (AH) is associated with a higher incidence of monozygotic twinning (MZT) in women undergoing assisted reproductive technology remains controversial; the aim of the study was to demonstrate the relationship between AH and MZT. A total of 8900 clinical pregnancies were selected among embryo transfer cycles from January 2011 to October 2019. Women receiving day (D) 3 embryos were divided into groups A–C: group A (n = 1651) and group B (n = 1045) included women aged ≤37 or ≥38 years, respectively, with zona pellucida (ZP) thinning; group C (n = 3865) included women aged ≤37 years without AH. Women aged ≤37 years who underwent blastocyst transfer and/or blastocyst ZP breaching were included in group D (n = 2339). The incidence of MZT was compared among groups A, B and C, and between groups C and D. The incidence of MZT in group B (2.2%) was significantly higher than in group A (1.0%), especially following intracytoplasmic sperm injection (ICSI), while the incidence of MZT in group A (1.0%) was significantly lower than in group C (2.2%). The MZT rate with in vitro fertilization was higher in group D (2.8%) than in group C (2.2%), but the MZT rate following ICSI was not significantly different between the two groups. ZP thinning of D3 embryos may increase the risk of MZT in older women (≥38 years), but decrease it in younger women (≤37 years). ZP breaching may be useful to reduce the incidence of MZT in ICSI-generated blastocysts.

In this paper, titanium doped (2 wt. %) indium oxide (TIO) thin films deposited on quartz substrates by DC sputtering were presented. Dealt with different temperatures from 420°C to 620°C of post-annealing in vacuum for 40 minuets, the samples display different optical and electric properties. The deposited films exhibited polycrystalline in the preferred (222) and (440) orientation, with higher mobility (up to 48.6 cm2/VS) and lower resistivity (1.26 ×10-4Ω·cm) at the post-annealing temperature of 520°C. The average optical transmittance of the films is over 92% in a wavelength range from 300 to 1100 nm and the transmittance has only around 1.8% change with different post-annealing temperatures.

The increasing worldwide interest in MnO2 for supercapacitor applications is based on anticipation that MnO2-based high-voltage aqueous supercapacitors will ultimately serve as a safe and low-cost alternative to state-of-the-art commercial organic-based electrochemical double-layer capacitors or RuO2-based acid systems. In this paper, the physicochemical features, synthesis methods, and charge storage mechanism of MnO2 as well as the current status of MnO2-based supercapacitors are summarized and discussed in detail. The future opportunities and challenges related to MnO2-based supercapacitors have also been proposed.