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This report explores key considerations in relation to adopting a dynamic discount rate funding approach and the impacts of doing so in a range of areas, including funding volatility, investment strategy and end game objectives. It considers the advantages and disadvantages of this approach from the perspective of a range of stakeholders and the challenges that need overcoming in order to fully implement and support the approach, for example data challenges and the new skills required in the industry. The report includes sample modelling to highlight the practical issues that arise when adopting this approach. It describes a step-by-step approach for assessing the risks to be considered when determining an appropriate level of assets to provide funding for a sample set of pension scheme cash flows, as summarised in the table below.
Steps involved in determining the funding buffer and discount rate
Step 1
Create an asset portfolio based on best estimate liability cash flows
Step 2
Adjustment for investment costs
Step 3
Buffer: allowance for asset-side risks
Step 4
Buffer: allowance for asset-liability mismatch risk (reinvestment and disinvestment risk)
Step 5
Buffer: allowance for liability-side risks
Step 6
Buffer: consideration of risk diversification when determining the buffer
It also considers how a dynamic discount rate approach fits within the proposed future funding regulations. Finally, the report puts forward recommendations for the IFoA, Scheme Actuaries and TPR.
Consequences of schemes adopting a dynamic discount rate approach could include very different investment strategies with investment in a wider pool of assets, less use of leveraged Liability Driven Investment, fewer schemes targeting buy-out as their end game strategy and an increase in technical work for actuaries in advising on the optimisation of asset and liability cash flows.
The internal surface area of Na-Wyoming bentonite was determined for linearly swelling pastes, using a physically based equation which describes such swelling. Information required is simply the linear relationship between interplatelet spacing, determined by X-ray powder diffraction, vs total water content determined gravimetrically. However, before the three-unknown parameter equation can be so applied, that portion of external-pore water, which normally increases linearly commensurately as interstitial water increases, must be decreased to zero. This was accomplished by adding dilute quantities of NaCl salt to the clay-paste system to decrease the attractive forces between positive-edge and negative-face sites, and stirring vigorously to further destroy the card-house structure and align the clay platelets.
Tight focusing with very small f-numbers is necessary to achieve the highest at-focus irradiances. However, tight focusing imposes strong demands on precise target positioning in-focus to achieve the highest on-target irradiance. We describe several near-infrared, visible, ultraviolet and soft and hard X-ray diagnostics employed in a ∼1022 W/cm2 laser–plasma experiment. We used nearly 10 J total energy femtosecond laser pulses focused into an approximately 1.3-μm focal spot on 5–20 μm thick stainless-steel targets. We discuss the applicability of these diagnostics to determine the best in-focus target position with approximately 5 μm accuracy (i.e., around half of the short Rayleigh length) and show that several diagnostics (in particular, 3$\omega$ reflection and on-axis hard X-rays) can ensure this accuracy. We demonstrated target positioning within several micrometers from the focus, ensuring over 80% of the ideal peak laser intensity on-target. Our approach is relatively fast (it requires 10–20 laser shots) and does not rely on the coincidence of low-power and high-power focal planes.
Medical-legal partnerships connect legal advocates to healthcare providers and settings. Maintaining effectiveness of medical-legal partnerships and consistently identifying opportunities for innovation and adaptation takes intentionality and effort. In this paper, we discuss ways in which our use of data and quality improvement methods have facilitated advocacy at both patient (client) and population levels as we collectively pursue better, more equitable outcomes.
The aim of this study was to identify and prioritize strategies for strengthening public health system resilience for pandemics, disasters, and other emergencies using a scorecard approach.
Methods:
The United Nations Public Health System Resilience Scorecard (Scorecard) was applied across 5 workshops in Slovenia, Turkey, and the United States of America. The workshops focused on participants reviewing and discussing 23 questions/indicators. A Likert type scale was used for scoring with zero being the lowest and 5 the highest. The workshop scores were analyzed and discussed by participants to prioritize areas of need and develop resilience strategies. Data from all workshops were aggregated, analyzed, and interpreted to develop priorities representative of participating locations.
Results:
Eight themes emerged representing the need for better integration of public health and disaster management systems. These include: assessing community disease burden; embedding long-term recovery groups in emergency systems; exploring mental health care needs; examining ecosystem risks; evaluating reserve funds; identifying what crisis communication strategies worked well; providing non-medical services; and reviewing resilience of existing facilities, alternate care sites, and institutions.
Conclusions:
The Scorecard is an effective tool for establishing baseline resilience and prioritizing actions. The strategies identified reflect areas in most need for investment to improve public health system resilience.
The Intensity Interferometry technique consists of measuring the spatial coherence (visibility) of an object via its intensity fluctuations over a sufficient range of telescope separations (baselines). This allows us to study the size, shape and morphology of stars with an unprecedented resolution. Cherenkov telescopes have a set of characteristics that coincidentally allow for Intensity Interferometry observations: very large reflective surfaces, sensitivity to individual photons, temporal resolution of nanoseconds and the fact that they come in groups of several telescopes. In the recent years, the MAGIC Collaboration has developed a deadtime-free Intensity Interferometry setup for its two 17 m diameter Cherenkov telescopes that includes a 4-channel GPU-based real-time correlator, 410–430 nm filters and new ways of splitting its primary mirrors into submirrors using Active Mirror Control (AMC). With this setup, MAGIC can operate as a long-baseline optical interferometer in the baseline range 40–90 m, which translates into angular resolutions of 0.5-1 mas. Additionally, thanks to its AMC, it can simultaneously measure the zero-baseline correlation or, by splitting into submirrors, access shorter baselines under 17 m in multiple u-v plane orientations. The best candidates to observe with this technique are relatively small and bright stars, in other words, massive stars (O, B and A types). We will present the science cases that are currently being proposed for this setup, as well as the prospects for the future of the system and technique, like the possibility of large-scale implementation with CTA.
This study aimed to describe the microscopic over-under cartilage tympanoplasty technique, provide hearing results and detail clinically significant complications.
Method
This was a retrospective case series chart review study of over-under cartilage tympanoplasty procedures performed by the senior author between January 2015 and January 2019 at three tertiary care centres. Cases were excluded for previous or intra-operative cholesteatoma, if a mastoidectomy was performed during the procedure or if ossiculoplasty was performed. Hearing results and complications were obtained.
Results
Sixty-eight tympanoplasty procedures met the inclusion criteria. The median age was 13 years (range, 3–71 years). The mean improvement in pure tone average was 6 dB (95 per cent confidence interval 4–9 dB; p < 0.0001). The overall perforation closure rate was 97 per cent (n = 66). Revision surgery was recommended for a total of 6 cases (9 per cent) including 2 post-operative perforations, 1 case of middle-ear cholesteatoma and 3 cases of external auditory canal scarring.
Conclusion
Over-under cartilage tympanoplasty is effective at improving clinically meaningful hearing with a low rate of post-operative complications.
OBJECTIVES/SPECIFIC AIMS: The objective of this research was to investigate the effect of alcohol and evocative stimuli on heart rate variability (HRV) in partners with a history of intimate partner violence in a placebo-controlled alcohol administration study with an emotion-regulation task. METHODS/STUDY POPULATION: In total, 17 partners (9 females, 8 males) with a history of partner violence participated in a placebo-controlled alcohol administration study with an emotion-regulation task during which HRV measures were collected. In the alcohol condition, participants were administered a mixture of 100 proof vodka and cranberry juice calculated to raise their blood alcohol concentration (BAC) to 0.08%. In the placebo condition, participants consumed a volume of juice equivalent to that consumed in the alcohol condition, but without alcohol. Alcohol and placebo conditions were counter-balanced across participants as were the presentation the blocks of evocative and neutral partner stimuli. RESULTS/ANTICIPATED RESULTS: Controlling for baseline HRV, there was a significant main effect of stimuli (evocative vs. neutral partner stimuli) on HRV in intoxicated partners, F1,16=16.28, p=0.004. There was also a significant main effect of regulation on HRV under conditions acute alcohol intoxication, F1,16=23.55, p=0.001. These effects tell us that intoxicated partners experienced reduced HRV when exposed to evocative stimuli from their partners. These effects also tell us that under acute alcohol intoxication, partners were less able to regulate their emotion when exposed to evocative stimuli than when they consumed a placebo beverage. DISCUSSION/SIGNIFICANCE OF IMPACT: These results suggest that increases in intimate partner violence under acute alcohol intoxication may be the result of reduce HRV. This reduction in HRV would contribute to partners’ inability to response with adaptively in conflict when intoxicated. They also suggest that HRV may be an important target for intervention with partner with a history of intimate partner violence. One method may be Heart Rate Variability Biofeedback which has been shown to increase parasympathetic nervous system functioning, autonomic stability, and emotion regulation.
Kalahari Group sediments accumulated in the Kalahari basin, which started forming during the breakup of Gondwana in the early Cretaceous. These sediments cover an extensive part of southern Africa and form a low-relief landscape. Current models assume that the Kalahari Group accumulated throughout the entire Cenozoic. However, chronology has been restricted to early–middle Cenozoic biostratigraphic correlations and to OSL dating of only the past ~ 300 ka. We present a new chronological framework that reveals a dynamic nature of sedimentation in the southern Kalahari. Cosmogenic burial ages obtained from a 55 m section of Kalahari Group sediments from the Mamatwan Mine, southern Kalahari, indicate that the majority of deposition at this location occurred rapidly at 1–1.2 Ma. This Pleistocene sequence overlies the Archaean basement, forming a significant hiatus that permits the possibility of many Phanerozoic cycles of deposition and erosion no longer preserved in the sedimentary record. Our data also establish the existence of a shallow early–middle Pleistocene water body that persisted for > 450 ka prior to this rapid period of deposition. Evidence from neighboring archeological excavations in southern Africa suggests an association of high-density hominin occupation with this water body.
The Dead Sea fault (DSF) is one of the most active plate boundaries in the world. Understanding the Quaternary history and sediments of the DSF requires investigation into the Neogene development of this plate boundary. DSF lateral motion preceded significant extension and rift morphology by ~10 Ma. Sediments of the Sedom Formation, dated here between 5.0 ± 0.5 Ma and 6.2−2.1+inf Ma, yielded extremely low 10Be concentrations and 26Al is absent. These reflect the antiquity of the sediments, deposited in the Sedom Lagoon, which evolved in a subdued landscape and was connected to the Mediterranean Sea. The base of the overlying Amora Formation, deposited in the terminal Amora Lake which developed under increasing relief that promoted escarpment incision, was dated at 3.3−0.8+0.9 Ma. Burial ages of fluvial sediments within caves (3.4 ± 0.2 Ma and 3.6 ± 0.4 Ma) represent the timing of initial incision. Initial DSF topography coincides with the earliest Red Sea MORB's and the East Anatolian fault initiation. These suggest a change in the relative Arabian–African plate motion. This change introduced the rifting component to the DSF followed by a significant subsidence, margin uplift, and a reorganization of relief and drainage pattern in the region resulting in the topographic framework observed today.
New 10Be ages from the summits of three mountain areas of North Wales reveal a very similar exposure timing as the Welsh Ice Cap thinned after the global Last Glacial Maximum. Eight bedrock and one boulder sample gave a combined arithmetic mean exposure age of 19.08 ± 0.80 ka (4.2%, 1σ). Similar exposure ages over a 320 m vertical range (824 to 581 m altitude) show that ice cap thinning was very rapid and spatially uniform. Using the same production rate and scaling scheme, we recalculated six published 10Be exposure ages from the nearby Arans, which also covered a similar elevation range from 608 to 901 m and obtained an arithmetic mean of 19.41 ± 1.45 ka (7.5%, 1σ). The average exposure age of all 15 accepted deglaciation ages is 19.21 ± 1.07 (5.6%, 1σ). The complete dataset from North Wales provides very strong evidence indicating that these summits became exposed as nunataks at 20–19 ka. This result provides important insight to the magnitude of ice surface lowering and behavior of the Welsh Ice Cap during the last deglaciation that can be compared to other ice masses that made up the British-Irish Ice Sheet.
To determine whether use of contact precautions on hospital ward patients is associated with patient adverse events
DESIGN
Individually matched prospective cohort study
SETTING
The University of Maryland Medical Center, a tertiary care hospital in Baltimore, Maryland
METHODS
A total of 296 medical or surgical inpatients admitted to non–intensive care unit hospital wards were enrolled at admission from January to November 2010. Patients on contact precautions were individually matched by hospital unit after an initial 3-day length of stay to patients not on contact precautions. Adverse events were detected by physician chart review and categorized as noninfectious, preventable and severe noninfectious, and infectious adverse events during the patient’s stay using the standardized Institute for Healthcare Improvement’s Global Trigger Tool.
RESULTS
The cohort of 148 patients on contact precautions at admission was matched with a cohort of 148 patients not on contact precautions. Of the total 296 subjects, 104 (35.1%) experienced at least 1 adverse event during their hospital stay. Contact precautions were associated with fewer noninfectious adverse events (rate ratio [RtR], 0.70; 95% confidence interval [CI], 0.51–0.95; P=.02) and although not statistically significant, with fewer severe adverse events (RtR, 0.69; 95% CI, 0.46–1.03; P=.07). Preventable adverse events did not significantly differ between patients on contact precautions and patients not on contact precautions (RtR, 0.85; 95% CI, 0.59–1.24; P=.41).
CONCLUSIONS
Hospital ward patients on contact precautions were less likely to experience noninfectious adverse events during their hospital stay than patients not on contact precautions.
Infect. Control Hosp. Epidemiol. 2015;36(11):1268–1274
Combining breadth of coverage with detail, this logical and cohesive introduction to insect ecology couples concepts with a broad range of examples and practical applications. It explores cutting-edge topics in the field, drawing on and highlighting the links between theory and the latest empirical studies. The sections are structured around a series of key topics, including behavioral ecology; species interactions; population ecology; food webs, communities and ecosystems; and broad patterns in nature. Chapters progress logically from the small scale to the large; from individual species through to species interactions, populations and communities. Application sections at the end of each chapter outline the practicality of ecological concepts and show how ecological information and concepts can be useful in agriculture, horticulture and forestry. Each chapter ends with a summary, providing a brief recap, followed by a set of questions and discussion topics designed to encourage independent and creative thinking.
Faecal moisture content can determine whether faeces appear soft or firm, and faecal character can influence whether owners are satisfied with a dog food. In a previous study, dogs appeared to produce softer faeces after noon. The purpose of the present study was to determine whether time of defecation affected canine faecal water content. A total of eight hound dogs were fed one of four canned diets as a single meal each morning for 1 week per diet in a Latin square design. All four diets contained approximately 77 % moisture and, on a DM basis, 24 MJ/kg gross energy, 23 % crude protein, 32 % crude fat, 31 % N-free extract and 1 % crude fibre. The proportion of dietary protein from soya-derived texturised vegetable protein (TVP):beef was 0:100, 14:86, 29:71 and 57:43, respectively. Soya carbohydrate partially replaced maize starch as TVP increased. Faeces were collected by direct catch during the sixth morning and afternoon of each diet period. Mean faecal moisture content was greater in the afternoon than in the morning (79 v. 71 %; P = 0·01) and increased with dietary TVP (P ≤ 0·0001), and there was an interaction between time of day and percentage TVP (P = 0·003). Faecal moisture content differed from morning to afternoon only with TVP in the diet. Faecal wet weight was similar from morning to afternoon. This suggests that time of day and presence of TVP from soya should be taken into account when evaluating the effect of a diet on faecal form and moisture content in dogs fed once daily.
The study of life histories involves the full span of life, from egg or sperm through reproduction and death. The ways in which individuals maximize progeny production and survival are about as diverse as the populations and species themselves. Research interest in life history is therefore strongly comparative, looking at the variation in life-history characteristics within populations, within species and among related species. As with ecology in general, we search for patterns in nature and develop hypotheses and theories, which account for the trends that we observe, and prompt new observations in a cycle of efforts to refine knowledge.
Understanding of life histories is fundamental to insect ecology, and we have covered many examples of life-history studies already in this book, and more will follow. Behavioral traits that promote fitness were covered in Chapter 2, and the evolution of life histories of social insects was discussed in Chapter 3. Chapter 4 included discussion of wing polymorphism in planthoppers (Figure 4.5), and jousting and territoriality of Pemphigus aphids (Figure 4.11). Density effects on planthopper fecundity and wing polymorphism were involved with competition (Chapter 5, Figure 5.8), and egg-laying schedules of a fruit fly were described in Chapter 9 (Figure 9.10). We noted also in Chapter 9 the differences between pro-ovigenic and synovigenic egg production, and the marked differences in survival of progeny portrayed in survivorship curves. In Chapter 6 different strategies of yucca moths were noted among true pollinators and two classes of cheaters (Figure 6.14). We also saw divergence of life-history types in scarab beetles (Figure 6.16) and the constraints on ovariole number and fecundity of parasitoid wasps and flies (Figure 8.4). Indeed, the study of life-history traits runs throughout ecology, and this is how it should be, because understanding the evolution of whole life histories is at the heart of understanding insects, and the evolutionary pathways along which they have traveled. This point is taken up again in the last section of this chapter on applications.
Everybody is conscious of insects, and even concerned about them. In fact, we each have an ecological relationship with their kind. We share our houses and gardens with them, our walks and picnics, and our adventures. So should we not understand them? Their richness in species and interactions, their beauty and behavioral intricacy, all enrich our lives if we understand who they are, and what they are doing. Therefore, the ecology of insects is for everybody.
Eisner (2003, p. 1), in his latest book, For Love of Insects, starts by writing that “This book is about the thrill of discovery.” And, Wilson (1994, p. 191), in his autobiographical, Naturalist, advised, “Love the organisms for themselves first, then strain for general explanations, and, with good fortune, discoveries will follow. If they don't, the love and the pleasure will have been enough.” Here is sound advice from two of the greatest practitioners of entomology and ecology, for discovery is thrilling, and the deeper the fascination one develops, the greater will be the discoveries that follow.
This book concludes with discussions on the broadest biological patterns we can observe on this Earth, and the reasons for their existence. We also examine smaller scales of variation that would be seen on the landscape and ecosystem levels. In doing so we pick up various topics discussed in previous chapters, such as the roles of time and space as influences on species richness, and expand this view to the global level, showing that the same factors remain important as we scale up our perspective to interactions on Earth. We also look at the paleobiological record again, as we did in Chapter 1 to note the long evolutionary history of insects, but in this section we examine the record for clues on what might be expected as global changes occur, and if predictions are possible.