We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
The Institute for Implementation Science Scholars (IS-2) is a dissemination and implementation (D&I) science training and mentoring program. A key component of IS-2 is collaborating and networking. To build knowledge on effective networking and mentoring, this study sought to 1) conduct a social network analysis to determine whether underrepresented scholars have equivalent levels of connection and 2) gain insights into the differences in networking among racial/ethnic subgroups of scholars.
Methods:
Social network survey data were used to select participants based on number of collaborative connections (highest, lowest) and racial/ ethnic category (underrepresented, not underrepresented). Interviews were recorded, transcribed, and coded using an iterative process.
Results:
The sample consisted of eight highly networked scholars, eight less networked scholars, seven from underrepresented racial and ethnic groups, and nine from not underrepresented groups. Qualitative data showed a lack of connection, reluctance to network, and systematic issues including institutional biases as possible drivers of group differences. In addition, scholars provided suggestions on how to overcome barriers to networking and provided insights into how IS-2 has impacted their D&I research and knowledge.
Conclusions:
Underrepresented scholars have fewer network contacts than not underrepresented scholars in the IS-2 training program. It is imperative for leadership to be intentional with mentorship pairing, especially for underrepresented scholars. Future research might include interviews with program leaders to understand how network pairings are built to improve the mentorship experience.
NASA’s all-sky survey mission, the Transiting Exoplanet Survey Satellite (TESS), is specifically engineered to detect exoplanets that transit bright stars. Thus far, TESS has successfully identified approximately 400 transiting exoplanets, in addition to roughly 6 000 candidate exoplanets pending confirmation. In this study, we present the results of our ongoing project, the Validation of Transiting Exoplanets using Statistical Tools (VaTEST). Our dedicated effort is focused on the confirmation and characterisation of new exoplanets through the application of statistical validation tools. Through a combination of ground-based telescope data, high-resolution imaging, and the utilisation of the statistical validation tool known as TRICERATOPS, we have successfully discovered eight potential super-Earths. These planets bear the designations: TOI-238b (1.61$^{+0.09} _{-0.10}$ R$_\oplus$), TOI-771b (1.42$^{+0.11} _{-0.09}$ R$_\oplus$), TOI-871b (1.66$^{+0.11} _{-0.11}$ R$_\oplus$), TOI-1467b (1.83$^{+0.16} _{-0.15}$ R$_\oplus$), TOI-1739b (1.69$^{+0.10} _{-0.08}$ R$_\oplus$), TOI-2068b (1.82$^{+0.16} _{-0.15}$ R$_\oplus$), TOI-4559b (1.42$^{+0.13} _{-0.11}$ R$_\oplus$), and TOI-5799b (1.62$^{+0.19} _{-0.13}$ R$_\oplus$). Among all these planets, six of them fall within the region known as ‘keystone planets’, which makes them particularly interesting for study. Based on the location of TOI-771b and TOI-4559b below the radius valley we characterised them as likely super-Earths, though radial velocity mass measurements for these planets will provide more details about their characterisation. It is noteworthy that planets within the size range investigated herein are absent from our own solar system, making their study crucial for gaining insights into the evolutionary stages between Earth and Neptune.
An urgent need exists to identify neural correlates associated with differing levels of suicide risk and develop novel, rapid-acting therapeutics to modulate activity within these neural networks.
Methods
Electrophysiological correlates of suicide were evaluated using magnetoencephalography (MEG) in 75 adults with differing levels of suicide risk. During MEG scanning, participants completed a modified Life-Death Implicit Association Task. MEG data were source-localized in the gamma (30–58 Hz) frequency, a proxy measure of excitation-inhibition balance. Dynamic causal modeling was used to evaluate differences in connectivity estimates between risk groups. A proof-of-concept, open-label, pilot study of five high risk participants examined changes in gamma power after administration of ketamine (0.5 mg/kg), an NMDAR antagonist with rapid anti-suicide ideation effects.
Results
Implicit self-associations with death were stronger in the highest suicide risk group relative to all other groups, which did not differ from each other. Higher gamma power for self-death compared to self-life associations was found in the orbitofrontal cortex for the highest risk group and the insula and posterior cingulate cortex for the lowest risk group. Connectivity estimates between these regions differentiated the highest risk group from the full sample. Implicit associations with death were not affected by ketamine, but enhanced gamma power was found for self-death associations in the left insula post-ketamine compared to baseline.
Conclusions
Differential implicit cognitive processing of life and death appears to be linked to suicide risk, highlighting the need for objective measures of suicidal states. Pharmacotherapies that modulate gamma activity, particularly in the insula, may help mitigate risk.
Decumulation Pathways are proposed to help achieve better retirement outcomes for those with Defined Contribution (DC) pensions. The DC fund is split into two parts, in proportions of the consumer’s choice. Most is allocated to the Pension Fund to provide a lifetime income, while the rest is placed in the Flexible Fund for flexible access and/or to leave as a legacy. The Flexible Fund is invested in flexi-access drawdown. The Pension Fund is invested in a guaranteed annuity, Collective Defined Contribution, or a Pooled Pension Fund which maintains individual DC funds but pools longevity risk between participants. An illustrative standard Decumulation Pathway is intended as a default solution, or can be tailored by the consumer. It uses the Pooled Pension Fund, an automated withdrawal strategy which ensures a lifetime income is provided and one that aims to increase in line with inflation, and a moderate risk investment strategy. The standard approach is evaluated using various metrics, indicating that it has as a strong chance of providing a higher income than could be obtained from an annuity or drawdown, with limited downside risk.
The International Mineralogical Association's approved amphibole nomenclature has been revised in order to simplify it, make it more consistent with divisions generally at 50%, define prefixes and modifiers more precisely and include new amphibole species discovered and named since 1978, when the previous scheme was approved. The same reference axes form the basis of the new scheme and most names are little changed but compound species names like tremolitic hornblende (now magnesiohornblende) are abolished and also crossite (now glaucophane or ferroglaucophane or magnesioriebeckite or riebeckite), tirodite (now manganocummingtonite) and dannemorite (now manganogrunerite). The 50% rule has been broken only to retain tremolite and actinolite as in the 1978 scheme so the sodic calcic amphibole range has therefore been expanded. Alkali amphiboles are now sodic amphiboles. The use of hyphens is defined. New amphibole names approved since 1978 include nyböite, leakeite, kornite, ungarettiite, sadanagaite and cannilloite. All abandoned names are listed. The formulae and source of the amphibole end member names are listed and procedures outlined to calculate Fe3+ and Fe2+ when not determined by analysis.
Antarctic and Southern Ocean science is vital to understanding natural variability, the processes that govern global change and the role of humans in the Earth and climate system. The potential for new knowledge to be gained from future Antarctic science is substantial. Therefore, the international Antarctic community came together to ‘scan the horizon’ to identify the highest priority scientific questions that researchers should aspire to answer in the next two decades and beyond. Wide consultation was a fundamental principle for the development of a collective, international view of the most important future directions in Antarctic science. From the many possibilities, the horizon scan identified 80 key scientific questions through structured debate, discussion, revision and voting. Questions were clustered into seven topics: i) Antarctic atmosphere and global connections, ii) Southern Ocean and sea ice in a warming world, iii) ice sheet and sea level, iv) the dynamic Earth, v) life on the precipice, vi) near-Earth space and beyond, and vii) human presence in Antarctica. Answering the questions identified by the horizon scan will require innovative experimental designs, novel applications of technology, invention of next-generation field and laboratory approaches, and expanded observing systems and networks. Unbiased, non-contaminating procedures will be required to retrieve the requisite air, biota, sediment, rock, ice and water samples. Sustained year-round access to Antarctica and the Southern Ocean will be essential to increase winter-time measurements. Improved models are needed that represent Antarctica and the Southern Ocean in the Earth System, and provide predictions at spatial and temporal resolutions useful for decision making. A co-ordinated portfolio of cross-disciplinary science, based on new models of international collaboration, will be essential as no scientist, programme or nation can realize these aspirations alone.
We provide a Hilbert-style axiomatization of the logic of ‘actually’, as well as a two-dimensional semantics with respect to which our logics are sound and complete. Our completeness results are quite general, pertaining to all such actuality logics that extend a normal and canonical modal basis. We also show that our logics have the strong finite model property and permit straightforward first-order extensions.
Dynamo theory, the study of the generation and maintenance of magnetic fields by fluid motions, is important in many areas of physics, ranging from stellar and galactic dynamics, through solar physics and geomagnetism, to reactor physics. This volume contains the lectures given by leading specialists, for an intensive course held at the Newton Institute, as part of a NATO Advanced Study Institute. The course was intended for beginning graduate students, so starts with background material, before leading on to describe areas closer to current research. Topics covered include planetary and solar dynamos, fast dynamos and the use of symmetry principles to derive evolution equations. Detailed bibliographies are provided. As the only modern introduction to the subject, this will be welcome reading for students in planetary and solar physics, plasma physics and astrophysics.
The spreading and diffusion of two-dimensional vortices subject to weak external random strain fields is examined. The response to such a field of given angular frequency depends on the profile of the vortex and can be calculated numerically. An effective diffusivity can be determined as a function of radius and may be used to evolve the profile over a long time scale, using a diffusion equation that is both nonlinear and non-local. This equation, containing an additional smoothing parameter, is simulated starting with a Gaussian vortex. Fine scale steps in the vorticity profile develop at the periphery of the vortex and these form a vorticity staircase. The effective diffusivity is high in the steps where the vorticity gradient is low: between the steps are barriers characterized by low effective diffusivity and high vorticity gradient. The steps then merge before the vorticity is finally swept out and this leaves a vortex with a compact core and a sharp edge. There is also an increase in the effective diffusion within an encircling surf zone.
In order to understand the properties of the evolution of the Gaussian vortex, an asymptotic model first proposed by Balmforth, Llewellyn Smith & Young (J. Fluid Mech., vol. 426, 2001, p. 95) is employed. The model is based on a vorticity distribution that consists of a compact vortex core surrounded by a skirt of relatively weak vorticity. Again simulations show the formation of fine scale vorticity steps within the skirt, followed by merger. The diffusion equation we develop has a tendency to generate vorticity steps on arbitrarily fine scales; these are limited in our numerical simulations by smoothing the effective diffusivity over small spatial scales.
A one-dimensional tiling is a bi-infinite string on a finite alphabet, and its tiling semigroup is an inverse semigroup whose elements are marked finite substrings of the tiling. We characterize the structure of these semigroups in the periodic case, in which the tiling is obtained by repetition of a fixed primitive word.
This paper examines the evolution of an axisymmetric two-dimensional vortex in a steadily rotating strain field and the dynamical interactions that can enhance vortex spreading through resonant behaviour. Starting with a point vortex localized at the origin, the applied strain field generates a cat's eye topology in the co-rotating streamfunction, localized around a radius rext. Now the vortex is allowed to spread viscously: initially rext lies outside the vortex, but as it spreads, vorticity is advected into the cat's eyes, leading to a local flattening of the mean profile of the vortex and so to enhanced mixing and spreading of the vortex. Together with this is a feedback: the response of the vortex to the external strain depends on the modified profile. The feedback is particularly strong when rext coincides with the radius rcat at which the vortex can support cat's eyes of infinitesimal width. There is a particular time at which this occurs, as these radii change with the viscous spread of the vortex: rext moves inwards and rcat outwards. This resonance behaviour leads to increased mixing of vorticity, along with a rapid stretching of vorticity contours and a sharp increase in the amplitude of the non-axisymmetric components. The dynamical feedback and enhanced diffusion are studied for viscously spreading vortices by means of numerical simulations of their time evolution, parameterized only by the Reynolds number R and the dimensionless strength A of the external strain field.
From trials with cotton (variety Stoneville 7A) grown on the Ord River Irrigation Area of Western Australia, the results of delaying insecticide protection of crops against Heliothis attack by four and eight weeks were re-examined. With each delay the crop set later when temperatures were cooler, the plants older and larger, and the accumulated insect damage greater. Yet there was no significant difference in the final number of bolls produced in each crop. The growth of cotton and the compensatory mechanisms of the plant indicated by the data were simulated by a simple computer model. A modification of the model to simulate the response of a cotton plant to attack by Heliothis larvae was also developed. Output from the model suggests that, under the conditions of the experiment, there is a theoretical maximum number of bolls produced by this cotton variety. To produce this maximum crop requires complete protection from Heliothis larvae, but the period of protection can be minimised.
In March 1988, there was an outbreak of infection by a strain of Salmonella saint-paul with a distinctive antigenic marker. A total of 143 reports were received between 1 March and 7 June. Preliminary investigations suggested that raw beansprouts were a possible source of infection and a case-control study confirmed the association. S. saint-paul of the epidemic type was isolated from samples of beansprouts on retail sale in different cities in the United Kingdom and from mung bean seeds on the premises of the producer who was most strongly associated with cases. In addition, Salmonella virchow PT34 was isolated from samples of raw beansprouts and was subsequently associated with seven cases of infection. Four other serotypes of salmonella were also isolated from beansprouts. On 8 April the public were advised to boil beansprouts for 15 seconds before consumption, and the premises of the one producer associated with many cases were closed. As a result of these actions there was a significant decrease in the number of infections with S. saint-paul.