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To evaluate the motor proficiency, identify risk factors for abnormal motor scores, and examine the relationship between motor proficiency and health-related quality of life in school-aged patients with CHD.
Study design:
Patients ≥ 4 years old referred to the cardiac neurodevelopmental program between June 2017 and April 2020 were included. Motor skills were evaluated by therapist-administered Bruininks-Oseretsky Test of Motor Proficiency Second-Edition Short Form and parent-reported Adaptive Behavior Assessment System and Patient-Reported Outcomes Measurement Inventory System Physical Functioning questionnaires. Neuropsychological status and health-related quality of life were assessed using a battery of validated questionnaires. Demographic, clinical, and educational variables were collected from electronic medical records. General linear modelling was used for multivariable analysis.
Results:
The median motor proficiency score was the 10th percentile, and the cohort (n = 272; mean age: 9.1 years) scored well below normative values on all administered neuropsychological questionnaires. In the final multivariable model, worse motor proficiency score was associated with family income, presence of a genetic syndrome, developmental delay recognised in infancy, abnormal neuroimaging, history of heart transplant, and executive dysfunction, and presence of an individualised education plan (p < 0.03 for all predictors). Worse motor proficiency correlated with reduced health-related quality of life. Parent-reported adaptive behaviour (p < 0.001) and physical functioning (p < 0.001) had a strong association with motor proficiency scores.
Conclusion:
This study highlights the need for continued motor screening for school-aged patients with CHD. Clinical factors, neuropsychological screening results, and health-related quality of life were associated with worse motor proficiency.
Identifying factors that may influence aflatoxin exposure in children under 5 years of age living in farming households in western Kenya.
Design:
We used a mixed methods design. The quantitative component entailed serial cross-sectional interviews in 250 farming households to examine crop processing and conservation practices, household food storage and consumption and local understandings of aflatoxins. Qualitative data collection included focus group discussions (N 7) and key informant interviews (N 13) to explore explanations of harvesting and post-harvesting techniques and perceptions of crop spoilage.
Setting:
The study was carried out in Asembo, a rural community where high rates of child stunting exist.
Participants:
A total of 250 female primary caregivers of children under 5 years of age and thirteen experts in farming and food management participated.
Results:
Study results showed that from a young age, children routinely ate maize-based dishes. Economic constraints and changing environmental patterns guided the application of sub-optimal crop practices involving early harvest, poor drying, mixing spoiled with good cereals and storing cereals in polypropylene bags in confined quarters occupied by humans and livestock and raising risks of aflatoxin contamination. Most (80 %) smallholder farmers were unaware of aflatoxins and their harmful economic and health consequences.
Conclusions:
Young children living in subsistence farming households may be at risk of exposure to aflatoxins and consequent ill health and stunting. Sustained efforts to increase awareness of the risks of aflatoxins and control measures among subsistence farmers could help to mitigate practices that raise exposure.
The decision to discontinue isolation in hospitalized patients with persistently positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) molecular testing is nuanced. Improvement in clinical status should be evaluated with expert consultation when considering whether discontinuation of isolation is appropriate. The cycle threshold value may serve as a useful adjunct to this decision-making process.
The Working Group was created at the 25th IAU General Assembly in Sydney, Australia, in July 2003 by the IAU Executive Council as a Working Group of IAU Executive. The aims of the Working Group are to evaluate the status of women in astronomy through the collection of statistics over all countries where astronomy research is carried out; and to establish strategies and actions that can help women to attain true equality as research astronomers, which will add enormous value to all of astronomy.
Researchers, institutional review boards (IRBs), participants in human subjects research, and their families face an important but largely neglected problem — how should incidental findings (IFs) be managed in human subjects research. If researchers unexpectedly stumble upon information of potential health or reproductive significance, should they seek expert evaluation, contact the participant’s physician, tell the research participant, or respond with some combination? What should consent forms and the entire consent process say about how IFs will be handled in research? What should IRBs require?
Chemical spray pyrolysis (CSP) is a technique in which compounds of the constituents of the thin film to be fabricated are dissolved in an aqueous solution which is subsequently sprayed onto a heated substrate using nitrogen as the atomizing gas. At relatively low substrate temperatures (150–400°C) chemical reactions take place in which film formation of the desired compound occurs concomitantly with the release of volatile chemical reactants. The technique has advantages that include: (1) simplicity, (2) low cost and simple equipment, (3) the ability to prepare films over large areas with various shapes with relative ease and (4) the possibility of varying the physical properties through chemical means in known ways at modest temperatures. Results on the preparation of CuInSe2 which is a defect dominated semiconductor of technological interest are presented. Both n- and p- type materials were prepared with resistivities varying from 10−2 – 104 ohm-cm illustrating the use of the control of solution chemistry to produce films with reproducibly controlled properties.
In both the United States and Europe, people's subjective perception of life's overall quality is not wholly reflected by their objective conditions: Riches do not necessarily bring satisfaction, nor are the poor always dissatisfied. In this chapter, we explore the recollections of recent Soviet emigrants about how satisfied they felt about their lives in the Soviet Union. We then identify the groups among whom satisfaction levels differed significantly.
The first goal is to discover how Soviet emigrants rated the quality of their lives in the Soviet Union during their last normal period of life in the Soviet Union (LNP). The data sought are the individual respondents' own assessments of the quality of their lives. The respondents' answers had a normative reference that is unique in Soviet studies, for it was the individuals' own expectations, values, and experiences that shaped their judgments. In order to minimize psychological weighting, they were asked to evaluate not Soviet society in general but their own life events.
Quality of life differs, of course, among different people. It also varies over time in an individual's life. There is a difference to be noted between an index of “happiness” (or “misery”), which assesses a momentary, fleeting state of one's feelings, and an index of satisfaction (or dissatisfaction), where reality is judged more soberly against one's expectations. It would be impossible to obtain a reliable index of happiness from Soviet emigrants because so much time has elapsed since the respondents lived in the Soviet Union.
The slowdown of growth in the Soviet economy has renewed interest in the agricultural productivity of the Soviet Union. The failure of agriculture to grow at the pace of industry has hampered overall expansion, and domestic crop failure has induced grain purchases abroad. The bottlenecks to Soviet agricultural growth and development are diverse. On the one hand, they may be inevitable, for the resource endowment of the Soviet Union, where the range of temperature is great and the level of precipitation is unpredictable, does not favor agriculture. On the other hand, they may be systemic, for Soviet agriculture has been criticized for weak labor incentives, stifling bureaucratic controls, and overly large farms.