Oncological and functional outcomes for T1-2 N0-1 (TNMv8) p16-positive oropharyngeal squamous cell carcinoma patients were analysed according to treatment: either transoral robotic surgery (TORS) (Surgery group – TORS and neck dissection ± adjuvant radiotherapy/chemoradiotherapy) or primary radiotherapy/chemoradiotherapy (Oncology group).

Single-centre retrospective observational study.

The two-year disease-free survival rate was 88 per cent for the Oncology group (n = 42) and 95 per cent for the Surgery group (n = 44). The two-year overall survival rate was 98 per cent for the Oncology group and 100 per cent for the Surgery group. The functional swallowing outcome at two years post-treatment was similar in both groups. Subgroup analysis showed patients treated with surgery-only with no adjuvant treatment had the best functional outcome whilst patients treated with surgery and post-operative chemoradiotherapy had the worst functional outcome.

The overall oncological and functional outcomes at two years were similar in both groups. Patients treated with surgery-only had the best functional outcome without compromised oncological outcome.

Timely intervention is beneficial to the effectiveness of eating disorder (ED) treatment, but limited capacity within ED services means that these disorders are often not treated with sufficient speed. This service evaluation extends previous research into guided self-help (GSH) for adults with bulimic spectrum EDs by assessing the feasibility, acceptability, and preliminary effectiveness of virtually delivered GSH using videoconferencing.

Patients with bulimia nervosa (BN), binge eating disorder (BED) and other specified feeding and eating disorders (OSFED) waiting for treatment in a large specialist adult ED out-patient service were offered virtually delivered GSH. The programme used an evidence-based cognitive behavioural self-help book. Individuals were supported by non-expert coaches, who delivered the eight-session programme via videoconferencing.

One hundred and thirty patients were allocated to a GSH coach between 1 September 2020 and 30 September 2022; 106 (82%) started treatment and 78 (60%) completed treatment. Amongst completers, there were large reductions in ED behaviours and attitudinal symptoms, measured by the ED-15. The largest effect sizes for change between pre- and post-treatment were seen for binge eating episode frequency (d = –0.89) and concerns around eating (d = –1.72). Patients from minoritised ethnic groups were over-represented in the non-completer group.

Virtually delivered GSH is feasible, acceptable and effective in reducing ED symptoms amongst those with bulimic spectrum disorders. Implementing virtually delivered GSH reduced waiting times, offering a potential solution for long waiting times for ED treatment. Further research is needed to compare GSH to other brief therapies and investigate barriers for patients from culturally diverse groups.

This study examined false positive rates of performance validity test (PVT) failure in a group of monolingual (English-speaking) White non-Hispanic/Latinx (non-HL), monolingual (English-speaking) Hispanic/Latinx (HL), and bilingual (English- and Spanish-speaking) HL patients evaluated at an academic medical center. Research on classification accuracy of embedded performance validity tests (PVTs) is limited in HL and bilingual populations. Cultural test biases or language differences could inaccurately cause scores below PVT cutoff levels.

The project involved secondary analysis of a deidentified dataset (N=391). Participants were included if they were between the ages of 18 and 64, had data from the initial visit, had an IQ greater than or equal to 70, were not diagnosed with dementia or major or mild cognitive impairment, and identified as either White non-HL or HL. Participants were required to have completed at least two PVTs. Participants who were not administered the Test of Memory Malingering (TOMM; n=95) or who scored below a highly sensitive Trial 1 cutoff (<46; n=86) were excluded. The final sample included 210 participants, which included monolingual non-HL participants (n=114), monolingual HL participants (n=44), and bilingual HL participants (n=52). Failure rates on eight PVTs were examined by participant group: Reliable Digit Span (RDS), Auditory Verbal Learning Test Recognition (AVLT), Logical Memory Recognition (LM), Visual Reproduction Recognition (VR), Trail Making Test Ratio (TMT rat), Rey Complex Figure Test Recognition (RCFT), Semantic Word Generation (animals; SWG), and Finger Tapping (TAP).

Groups were not significantly different in age. Monolingual non-HL participants had completed more years of education than monolingual and bilingual HL groups (13.7, 12.7, and 12.8 years respectively). In the whole sample, 8.6% (n=18) failed two or more PVTs. In the monolingual non-HL group, 8.8% (n=10) failed two or more PVTs, while 9.1% (n=4) of the monolingual HL group and 7.7% (n=4) of the bilingual HL group failed two or more PVTs (n.s.). Within the monolingual non-HL test set, failure rates were above 10% on SWG (12.73%) and TAP (17.7%). Failure rates above 10% in the monolingual HL set were found on SWG (11.6%). Failure rates above 10% in bilingual HL measures were observed on SWG (13.5%) and TAP (10.8%).

Total PVT failure rates did not significantly differ between groups. Across groups, performance was above a common false positive threshold of 10% on SWG. Monolingual non-HL and bilingual participants also had elevated failure rates on TAP.