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Recent changes to US research funding are having far-reaching consequences that imperil the integrity of science and the provision of care to vulnerable populations. Resisting these changes, the BJPsych Portfolio reaffirms its commitment to publishing mental science and advancing psychiatric knowledge that improves the mental health of one and all.
NASA’s all-sky survey mission, the Transiting Exoplanet Survey Satellite (TESS), is specifically engineered to detect exoplanets that transit bright stars. Thus far, TESS has successfully identified approximately 400 transiting exoplanets, in addition to roughly 6 000 candidate exoplanets pending confirmation. In this study, we present the results of our ongoing project, the Validation of Transiting Exoplanets using Statistical Tools (VaTEST). Our dedicated effort is focused on the confirmation and characterisation of new exoplanets through the application of statistical validation tools. Through a combination of ground-based telescope data, high-resolution imaging, and the utilisation of the statistical validation tool known as TRICERATOPS, we have successfully discovered eight potential super-Earths. These planets bear the designations: TOI-238b (1.61$^{+0.09} _{-0.10}$ R$_\oplus$), TOI-771b (1.42$^{+0.11} _{-0.09}$ R$_\oplus$), TOI-871b (1.66$^{+0.11} _{-0.11}$ R$_\oplus$), TOI-1467b (1.83$^{+0.16} _{-0.15}$ R$_\oplus$), TOI-1739b (1.69$^{+0.10} _{-0.08}$ R$_\oplus$), TOI-2068b (1.82$^{+0.16} _{-0.15}$ R$_\oplus$), TOI-4559b (1.42$^{+0.13} _{-0.11}$ R$_\oplus$), and TOI-5799b (1.62$^{+0.19} _{-0.13}$ R$_\oplus$). Among all these planets, six of them fall within the region known as ‘keystone planets’, which makes them particularly interesting for study. Based on the location of TOI-771b and TOI-4559b below the radius valley we characterised them as likely super-Earths, though radial velocity mass measurements for these planets will provide more details about their characterisation. It is noteworthy that planets within the size range investigated herein are absent from our own solar system, making their study crucial for gaining insights into the evolutionary stages between Earth and Neptune.
Intensity in adolescent romantic relationships was examined as a long-term predictor of higher adult blood pressure in a community sample followed from age 17 to 31 years. Romantic intensity in adolescence – measured via the amount of time spent alone with a partner and the duration of the relationship – was predicted by parents’ psychologically controlling behavior and was in turn found to predict higher resting adult systolic and diastolic blood pressure even after accounting for relevant covariates. The prediction to adult blood pressure was partially mediated via conflict in nonromantic adult friendships and intensity in adult romantic relationships. Even after accounting for these mediators, however, a direct path from adolescent romantic intensity to higher adult blood pressure remained. Neither family income in adolescence nor trait measures of personality assessed in adulthood accounted for these findings. The results of this study are interpreted both as providing further support for the view that adolescent social relationship qualities have substantial long-term implications for adult health, as well as suggesting a potential physiological mechanism by which adolescent relationships may be linked to adult health outcomes.
Patients with schizophrenia spectrum disorders have been increasingly recognised to form cognitive subgroups with differential levels of impairment. Using cluster analytical techniques, this study sought to identify cognitive clusters in a sample of first-episode psychosis (FEP) patients and examine clinical and developmental differences across the resultant groups.
Methods
In total, 105 FEP patients in the University of California Los Angeles Aftercare Research Program were assessed for cognition, symptoms and premorbid developmental adjustment. Hierarchical cluster analysis with Ward's method and squared Euclidean distance was conducted, confirmed by discriminant function analysis and optimised with k-means clustering. The stability of the solution was evaluated through split-sample (random, 80 and 70% samples) and alternate method (average linkage method) replication via Cohen's κ analysis. Controlling for multiple comparisons, one-way analysis of variances examined group differences in symptom severity and premorbid adjustment.
Results
Three groups were identified: severely impaired (n = 27), moderately impaired (n = 41) and relatively intact (n = 37). There were no significant differences in symptom severity across the groups. Significant differences were observed for scholastic performance at three different developmental stages: childhood, early adolescence and late adolescence, with the relatively intact group demonstrating significantly better scholastic performance at all three stages than both the moderately impaired and severely impaired groups (who did not significantly differ from each other).
Conclusions
The findings add to growing evidence that cognitive clusters in FEP mirror that of later-stage schizophrenia. They also suggest that premorbid scholastic performance may not just be a risk factor for developing schizophrenia, but is also related to cognitive impairment severity and potentially to prognosis.
While studies suggest that nutritional supplementation may reduce aggressive behavior in children, few have examined their effects on specific forms of aggression. This study tests the primary hypothesis that omega-3 (ω-3), both alone and in conjunction with social skills training, will have particular post-treatment efficacy for reducing childhood reactive aggression relative to baseline.
Methods
In this randomized, double-blind, stratified, placebo-controlled, factorial trial, a clinical sample of 282 children with externalizing behavior aged 7–16 years was randomized into ω-3 only, social skills only, ω-3 + social skills, and placebo control groups. Treatment duration was 6 months. The primary outcome measure was reactive aggression collected at 0, 3, 6, 9, and 12 months, with antisocial behavior as a secondary outcome.
Results
Children in the ω-3-only group showed a short-term reduction (at 3 and 6 months) in self-report reactive aggression, and also a short-term reduction in overall antisocial behavior. Sensitivity analyses and a robustness check replicated significant interaction effects. Effect sizes (d) were small, ranging from 0.17 to 0.31.
Conclusions
Findings provide some initial support for the efficacy of ω-3 in reducing reactive aggression over and above standard care (medication and parent training), but yield only preliminary and limited support for the efficacy of ω-3 in reducing overall externalizing behavior in children. Future studies could test further whether ω-3 shows promise in reducing more reactive, impulsive forms of aggression.
Struggles managing conflict and hostility in adolescent social relationships were examined as long-term predictors of immune-mediated inflammation in adulthood that has been linked to long-term health outcomes. Circulating levels of interleukin-6 (IL-6), a marker of immune system dysfunction when chronically elevated, were assessed at age 28 in a community sample of 127 individuals followed via multiple methods and reporters from ages 13 to 28. Adult serum IL-6 levels were predicted across periods as long as 15 years by adolescents’ inability to defuse peer aggression and poor peer-rated conflict resolution skills, and by independently observed romantic partner hostility in late adolescence. Adult relationship difficulties also predicted higher IL-6 levels but did not mediate predictions from adolescent-era conflict struggles. Predictions were also not mediated by adult trait hostility or aggressive behavior, suggesting the unique role of struggles with conflict and hostility from others during adolescence. The implications for understanding the import of adolescent peer relationships for life span physical health outcomes are considered.
The purpose of the present study was to examine the effects of food label nutrition colouring schemes in interaction with food category healthiness on consumers’ perceptions of food healthiness. Three streams of colour theory (colour attention, colour association and colour approach-avoidance) in interaction with heuristic processing theory provide consonant predictions and explanations for the underlying psychological processes.
Design
A 2 (food category healthiness: healthy v. unhealthy)×3 (food label nutrient colouring schemes: healthy=green, unhealthy=red (HGUR) v. healthy=red, unhealthy=green (HRUG) v. no colour (control)) between-subjects design was used.
Setting
The research setting was a randomised-controlled experiment using varying formats of food packages and nutritional information colouring.
Subjects
Respondents (n 196) sourced from a national consumer panel, USA.
Results
The findings suggest that, for healthy foods, the nutritional colouring schemes reduced perceived healthiness, irrespective of which nutrients were coloured red or green (healthinesscontrol=4·86; healthinessHGUR=4·10; healthinessHRUG=3·70). In contrast, for unhealthy foods, there was no significant difference in perceptions of food healthiness when comparing different colouring schemes against the control.
Conclusions
The results make an important qualification to the common belief that colour coding can enhance the correct interpretation of nutrition information and suggest that this incentive may not necessarily support healthier food choices in all situations.
This timely volume reviews the rapidly changing international economic environment and raises a range of issues and concerns pertaining to recent developments and the future of AFTA, ASEAN Free Trade Area. Part one is devoted to thematic analyses and perspectives dealing with trade; enlarging the ASEAN regional grouping; and relations with the World Trade Organization (WTO). Part two analyses AFTA in a wider comparative perspectives, examining relationships with the major trading partners of ASEAN, namely the United States (and more broadly NAFTA); Japan; and the European Union.
Sequential decision problems can often be modeled as Markov decision processes. Classical solution approaches assume that the parameters of the model are known. However, model parameters are usually estimated and uncertain in practice. As a result, managers are often interested in how estimation errors affect the optimal solution. In this paper we illustrate how sensitivity analysis can be performed directly for a Markov decision process with uncertain reward parameters using the Bellman equations. In particular, we consider problems involving (i) a single stationary parameter, (ii) multiple stationary parameters, and (iii) multiple nonstationary parameters. We illustrate the applicability of this work through a capacitated stochastic lot-sizing problem.
Spherically symmetric plasmas with high expansion velocities have been produced by irradiating targets with eight beams from the Helios CO2 laser in the presence of gases at various pressures. Attention was given to the properties of the target-emitted ions in order to obtain information about the ion acceleration mechanisms in plasma expansions. Photo-ionization of the ambient gases by the soft X-ray emission from the laser-irradiated targets produced background plasmas, permitting plasma counterstreaming experiments to be performed in spherical geometry. Successful laser-target coupling in the presence of background gases is obtained, modification of the ion acceleration in accordance with isothermal-expansion models is observed, and an absence of collective coupling between collisionless counterstreaming plasmas is found.
To assess the religious spirituality of EMSpersonnel and their perception of the spiritualneeds of ambulance patients.
Methods:
Emergency medical technicians (EMTs) andparamedics presenting to an urban, academicemergency department (ED) were asked to complete athree-part survey relating to demographics,personal practices, and perceived patient needs.Their responses were compared to those ofambulance patients presenting to an ED during aprevious study period and administered a similarsurvey.
Results:
A total of 143 EMTs and 89 paramedics returnedthe surveys. There were 161 (69.4%) male and 71(30.6%) female respondents with a median age rangeof 26–35 years old. Eighty-seven percent believedin God, 82% practiced prayer or meditation, 62%attended religious services occasionally, 55%belonged to a religious organization, 39% feltthat their beliefs affected their job, and 18%regularly read religious material. This wassimilar to the characteristics of ambulancepatients.
However, only 43% felt that occasionallyambulance patients presented with spiritualconcerns and 78% reported never or rarelydiscussing spiritual issues with patients.Contrastingly, >40% of ambulance patientsreported spiritual needs or concerns at the timeof ED presentation, and >50% wanted theirproviders to discuss their beliefs. Twenty-sixpercent of respondents reported praying ormeditating with patients, while 50% reportedpraying or meditating for patients.
Females were no more religious or spiritual thanmales, but were more likely to engage in prayerwith (OR = 2.38, p = 0.0049) orfor (OR = 6.45, p <0.0001)patients than their male counterparts.
Conclusion:
EMTs and paramedics did not perceive spiritualconcerns as often as reported by ambulancepatients, nor did they commonly inquire about thereligious/spiritual needs of patients.
Filtrations of modules over wreath products of algebras are studied and corresponding multiplicity formulas are given in terms of Littlewood–Richardson coefficients. An example relevant to Jantzen filtrations in Schur algebras is presented.
We study Rouquier blocks of symmetric groups and Schur algebras in detail, and obtain explicit descriptions for the radical layers of the principal indecomposable, Weyl, Young and Specht modules of these blocks. At the same time, the Jantzen filtrations of the Weyl modules are shown to coincide with their radical filtrations. We also address the conjectures of Martin, Lascoux–Leclerc–Thibon–Rouquier and James for these blocks.
In this paper, what is already known about defect 2 blocks of symmetric groups is used to deduce information about the corresponding blocks of Schur algebras. This information includes Ext-quivers and decomposition numbers, as well as Loewy structures of the Weyl modules, principal indecomposable modules and tilting modules.