We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
To investigate associations between multimodal analgesia and post-operative pain among patients undergoing transoral robotic surgery for oropharyngeal squamous cell carcinoma.
Methods
Records of patients who underwent surgery from 5 September 2012 to 30 November 2016 were abstracted. Associations were assessed using multivariable analysis.
Results
A total of 216 patients (mean age of 59.1 years, 89.4 per cent male) underwent transoral robotic surgery (92.6 per cent were human papilloma virus positive, 87.5 per cent had stage T1–T2 tumours, and 82.9 per cent had stage N0–N1 nodes). Gabapentin (n = 86) was not associated with a reduction in severe pain. Ibuprofen (n = 72) was administered less often in patients with severe pain. Gabapentin was not associated with increased post-operative sedation (p = 0.624) and ibuprofen was not associated with increased bleeding (p = 0.221). Post-operative opioid usage was not associated with surgical duration, pharyngotomy, bilateral neck dissections, tumour stage, tumour size, subsite or gabapentin.
Conclusion
Scheduled low-dose gabapentin was not associated with improved pain control or increased respiratory depression. Ibuprofen was not associated with an increased risk of bleeding and may be under-utilised.
To determine chemical composition, physical characteristics and standardized ileal digestibility (SID) of CP and amino acids (AA) in eight current hulled barley genotypes, an experiment with growing pigs has been conducted. These genotypes included Yool, Campanile, Lomerit, Travira, Anisette, Canberra, Metaxa and Fridericus. Growing barrows with an average initial BW of 30±2 kg were surgically fitted with simple T-cannulas at the distal ileum, and allotted to an 8×9 Youden square design with eight periods of 6 days each and nine pigs. Barley was the sole dietary source of CP and AA. On average, the eight genotypes contained on as-fed basis 10.7% CP, 15.2% total non-starch polysaccharides (NSP), 17.1% NDF and 4.1% β-glucan, and had a mean test weight (TW) of 72.2 kg/hl. The SID of CP in the barley genotypes varied from 69% to 74%, and was greater (P<0.01) for genotypes Travira, Anisette and Metaxa compared to Yool and Campanile. Standardized ileal digestibility of Lys, Met and Trp (P<0.05) but not of Thr differed between genotypes. Moreover, barley genotypes differed in their standardized ileal digestible content (cSID) of CP and AA. Furthermore, SID and cSID of CP and most AA linearly decreased (P<0.05) with increasing NDF and total sugar content. Standardized ileal digestibility of CP and some AA and cSID of CP and most AA decreased linearly with increasing TW (P<0.05). Additionally, SID and cSID of CP and AA of most barley genotypes were lower when compared to tabulated values. In conclusion, a comprehensive database on chemical composition and SID of CP and AA in eight current barley genotypes has been made available. However, as present SID values are lower compared to feed tables, adjustments are required to minimize the risk of overestimating the actual protein value of barley for pigs.
The two subgenera and 20 species of the crab spider genus Ebo in North America north of Mexico are described or redescribed, keyed, and illustrated. The subgenus Ebo contains seven species, of which E. iviei, E. evansae, E. contrasts, and E. punctatus are described as new and the female of E. merkeli Schick is described for the first time. The subgenus Titanebo contains 13 species, of which E. cantralli is described as new and the female of E. texanus is described for the first time.
Multisomatoform disorder is characterised by severe and disabling bodily symptoms, and pain is one of the most common and impairing of these. Furthermore, these bodily symptoms cannot be explained by an underlying organic disorder. Patients with multisomatoform disorder are commonly found at all levels of healthcare and are typically difficult to treat for physicians as well as for mental health specialists.
Aims
To test whether brief psychodynamic interpersonal therapy (PIT) effectively improves the physical quality of life in patients who have had multisomatoform disorder for at least 2 years.
Method
We recruited 211 patients (from six German academic out-patient centres) who met the criteria for multisomatoform disorder for a randomised, controlled, 12-week, parallel-group trial from 1 July 2006 to 1 January 2009 (International Standard Randomised Controlled Trial Number ISRCTN23215121). We randomly assigned the patients to receive either 12 weekly sessions of PIT (n = 107) or three sessions of enhanced medical care (EMC, n = 104). The physical component summary of the Short Form Health Survey (SF-36) was the pre-specified primary outcome at a 9-month follow-up.
Results
Psychodynamic interpersonal therapy improved patients' physical quality of life at follow-up better than EMC (mean improvement in SF-36 score: PIT 5.3, EMC 2.2), with a small to medium between-group effect size (d = 0.42, 95% CI 0.15–0.69, P = 0.001). We also observed a significant improvement in somatisation but not in depression, health anxiety or healthcare utilisation.
Conclusions
This trial documents the long-term efficacy of brief PIT for improving the physical quality of life in patients with multiple, difficult-to-treat, medically unexplained symptoms.
H and He features in photospheric spectra have rarely been used to constrain the structure of Type IIb/Ib/Ic supernovae (SNe IIb/Ib/Ic). The lines have to be modelled with a detailed non-local-thermodynamic-equilibrium (NLTE) treatment, including effects uncommon in stars. Once this is done, however, one obtains valuable hints on the characteristics of progenitors and explosions (composition, explosion energy, . . .). We have extended a radiative transfer code to compute synthetic spectra of SNe IIb, Ib and Ic. Here, we discuss our first larger set of models, focusing on the question: How much H/He can be hidden (i.e. remain undetected in photospheric spectra) in SNe Ib/Ic? For the SNe studied (relatively low Mej = 1. . .3 M⊙), we find a limit of MHe ≲ 0.1 M⊙ in SNe Ic (no unambiguous He lines). Stellar evolution models for single stars normally always yield higher masses. We suggest that low- or moderate-mass SNe Ic result from efficient envelope stripping in binaries. We propose similar studies on H/He in high-mass and extremely aspherical SNe, and observations covering the region of He I λ 20581.
The study was conducted to validate in vitro prediction of standardised ileal digestibilities (SID) of crude protein (CP) and amino acids (AA) in grain legumes for growing pigs using six different cultivars of faba beans (Vicia faba), six different cultivars of field peas (Pisum sativum), and five different cultivars of lupins (Lupinus spp.). The SID for CP and AA were predicted from in vitro analysis by means of a two-step enzymatic method using pepsin and pancreatin incubations. In vitro predicted SID values of CP and AA were generally higher than the corresponding SID values measured in vivo. There were strong linear relationships (r2 = 0.73 for Lys to r2 = 0.91 for Cys and Trp) between in vivo and in vitro predicted SID values in the assay feed ingredients if grain legume species (i.e. faba beans, field peas and lupins) was included as a covariate in multiple linear regression analysis. However, to rapidly and accurately predict SID of CP and AA in individual batches of various feed ingredients, further studies are warranted.
Let σ be a finite relational signature, let be a set of finite complete relational structures of signature σ, and let be the countable homogeneous relational structure of signature σ which does not embed any of the structures in .
When σ consists of at most binary relations and is finite, the vertex partition behaviour of is completely analysed, in the sense that it is shown that a canonical partition exists and the size of this partition in terms of the structures in is determined. If is infinite some results are obtained, but a complete analysis is still missing.
Some general results are presented which are intended to be used in further investigations when σ contains relational symbols of arity larger than two or when the set of bounds is infinite.
We investigate by photoluminescence (PL) nominally undoped, commercially available Zinc Oxide substrates (from Eagle Picher) grown by seeded chemical vapor transport technique in order to identify residual donors and acceptors. In low temperature PL spectra the dominant emission comes from the decay of bound exciton lines at around 3.36 eV. Zeeman measurements allow the identification of the two strongest lines and some weaker lines in-between as donorrelated. From the associated two-electron satellite lines binding energies of the major donors of 48 meV and 55 meV, respectively, can be deduced.
We determine minimal elements, i.e., atoms, in certain partial ordersoffactor closed languages under ⊆. This is in analogy tostructuralRamsey theory which determines minimal structures in partial ordersunderembedding.
This paper presents the results of a research project that investigated the potential benefits of a combined Galileo/GPS navigation system. The research addressed in detail the two key required navigation performance (RNP) parameters of accuracy and integrity. The project was supported by Alcatel Space and was a contribution to the Galileo definition studies (supported by the European Community under the GALA project). The results show significant improvements in both accuracy and integrity (achievable through RAIM) when a combined constellation is used rather than Galileo alone.
Let be a finite set of finite tournaments. We will give a necessary and sufficient condition for the -free homogeneous directed graph to be divisible. That is, that there is a partition of into two classes such that neither of them contains an isomorphic copy of .
For graphs A, B and a positive integer r, the relation means that whenever Δ is an r-colouring of the vertices of A, then there is an embedding ϕ of B into A such that Δ ∘ ϕ is constant. A class of graphs has the Ramsey property if, for every , there is an such that . For a given finite graph G, let Forb(G) denote the class of all finite graphs which do not embed G. It is known that, if G is 2-connected, then Forb() has the Ramsey property, and Forb(G) has the Ramsey property if and only if Forb(G) also has the Ramsey property. In this paper we show that if neither G nor its complement is 2-connected, then either (i) G has a cut point adjacent to every other vertex, or (ii) G has a cut point adjacent to every other vertex except one. We show that Forb(G) has the Ramsey property if G is a path of length 2 or 3, but that Forb(G) does not have the Ramsey property if (i) holds and G is not the path of length 2.
This paper is devoted to settling the following problem on (infinite, partially) ordered sets: Is there always a partition (2-coloring) of an ordered set X so that all nontrivial maximal chains of X meet both classes (receive both colors)? We show this is true for all countable ordered sets and provide counterexamples of cardinality N3. Variants of the problem are also considered and open problems specified.
Attempts to identify intermediates in an alkoxide-based solution route to films of the high temperature superconductor YBa2Cu3O7 reported by Fahrenholtz et al.[1] have led to the isolation of the first molecular barium-copper cluster, Ba2Cu2(OR)4(acac)4·2 HOR, R = CH2CH2OCH3. The extension of this route to the preparation of the bismuth superconductors has necessitated the investigation of bismuth alkoxide chemistry. Two separate routes to bismuth alkoxides have been examined: the metathesis of the metal halides with NaOR, (R = t-butyl, and diisopropylphenoxide) and the alcoholysis of bismuth amides, Bi(NR2)3, [R = N(SiMe3)2] The alcoholysis preparation gives high yields of several alkoxides suitable as precursors to the high Tc materials. A monomeric bismuth phenoxide, which is targeted as a volatile precursor, and a bismuth t-butoxide cluster have been isolated and stucturally characterized. Solubility and volatility studies have also been undertaken.
Fluorination of YBa2Cu3O7−s at room temperature results in no change of the critical temperature but a drastic reduction of superconducting volume fraction as determined by magnetic flux exclusion measurements. Rietveld refinement of neutron powder diffraction data indicates that the bulk structure has not changed in any significant way despite the loss of superconductivity. In marked contrast, when the superconducting oxide is fluorinated at 400 °C, a structural transformation from orthorhombic to tetragonal symmetry occurs that is accompanied by essentially complete filling of eight of the nine perovskite anion sites and total loss of superconductivity above 7 K. Interpretation of neutron activation analysis and neutron diffraction results render the formula of the fluorinated product as YBa2Cu3F3.5O4.5, but fluoride ions in the unit cell were not distinguished from oxide ions.
Powdered samples of the high-temperature superconductors A Ba2Cu3O7−δ (A = Gd,Y) were treated with fluorine gas (100 Torr) at room temperature and 400 °C for varying times (12–64 h). Magnetic shielding measurements on fluorinated products showed that the superconducting volume fraction in treated samples was greatly reduced or even completely eradicated. All samples were structurally characterized by x-ray powder diffraction. Two yttrium samples, one fluorinated at 25 °C and one at 400 °, were also examined by neutron powder diffraction. For samples treated at room temperature, no change in the structure or composition of the products was apparent by either technique. However, samples fluorinated at 400 °C are tetragonal, with a = 3.8641 (3), c = 11.704(1) Å, and bulk composition corresponding to the formula YBa2Cu3F3.5O4.5. Nuclear activation analysis, nuclear reaction analysis, and Auger spectroscopy were used to determine fluorine concentration and distribution in the fluorinated materials. For samples treated at room temperature, fluorine was found primarily within approximately 1 μm of the surface of the product particles. No evidence for a fluorinecontaining superconducting phase was found in any sample; fluorine was found to be detrimental to superconductivity in all cases. These results suggest that the 123 oxides are sensitive to surface effects.
As a contribution to various investigations [1-11] about packing of convex bodies with certain conditions imposed on the number of neighbours of each body, V. Chvátal [12] recently proved the following theorem: If in a packing of translates of a square each square has at least six neighbours then the density of the packing is at least 11/15.
Let E be a finite set containing n elements, n ≡ 1, 3 (mod 6), S = S(E) a Steiner triple system on E, i.e. each unordered pair of elements of E is a subset of exactly one triple in S. Let T be a subset of E such that none of the triples of elements of T is a member of S. Erdös has asked (in a recent letter to the authors) for the maximal size of such a set T. Denote max |T| for fixed n and S by f(n, S). We prove in this note the following result:
(i)
(ii) for every n ≡ 1, 3 (mod 6) there exists a Steiner triple system S0 such that equality holds in i.
A set of points (edges) of a graph is independent if no two distinct members of the set are adjacent. Gallai (1) observed that, if A0 (B0) is the minimum number of points (edges) of a finite graph covering all the edges (points) and A1 (B1) is the maximum number of independent points (edges), then:
holds, where m is the number of points of the graph.
The concepts of independence and covering are generalized in various ways for n-graphs. In this paper we establish certain connections between the corresponding extreme numbers analogous to the above result of Gallai.
Ray-Chaudhuri considered (2) independence and covering problems in n-graphs and determined algorithms for finding the minimal cover and some associated numbers.
Recommend this
Email your librarian or administrator to recommend adding this to your organisation's collection.