We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
The ASACUSA (atomic spectroscopy and collisions using slow antiprotons) Cusp experiment requires the production of dense positron plasmas with a high repetition rate to produce a beam of antihydrogen. In this work, details of the positron production apparatus used for the first observation of the antihydrogen beam, and subsequent measurements, are described in detail. This apparatus replaced the previous compact trap design resulting in an improvement in the positron accumulation rate by a factor of $52\pm 3$.
Methods for reducing the radius, temperature and space charge of a non-neutral plasma are usually reported for conditions which approximate an ideal Penning Malmberg trap. Here, we show that (i) similar methods are still effective under surprisingly adverse circumstances: we perform strong drive regime (SDR) compression and SDREVC in a strong magnetic mirror field using only 3 out of 4 rotating wall petals. In addition, we demonstrate (ii) an alternative to SDREVC, using e-kick instead of evaporative cooling (EVC) and (iii) an upper limit for how much plasma can be cooled to $T<20\ \mathrm {K}$ using EVC. This limit depends on the space charge, not on the number of particles or the plasma density.
To determine the prevalence of underweight, overweight and obesity in French youth from 2009 to 2013 and to determine if there are differences in weight categories according to socio-economic status.
Design
Cross-sectional study performed in different regions of France. Physical measures included weight, height and BMI. Underweight, overweight and obesity were defined according to age- and sex-specific BMI cut-off points from the International Obesity Task Force.
Setting
France.
Subjects
Children and adolescents (n 9670; 4836 boys, 4834 girls) from the French national BOUGE Program between 2009 and 2013.
Results
The prevalence of obesity was higher in boys than girls (P<0·05). In contrast, underweight was more prevalent in girls (P<0·05). Although there were no significant changes in overweight or underweight boys or girls from 2009 to 2013, there was a significant increase in obesity in boys and girls (P<0·05) during the same time period. The prevalence of underweight increased in girls from 12·0 to 16·7 % (P >0·05) and remained unchanged in boys (7·1–7·3 %) between 2009 and 2013. Overweight and obesity were higher in low socio-economic families (P<0·0001).
Conclusions
Findings suggest that the prevalence of overweight was stable although high in French children and adolescents, while the prevalence of obesity increased significantly. Changes in underweight, although not significant, were high in girls and merit further attention. Improving public health interventions, especially in high-risk low socio-economic populations, may help to modify the behaviour that contributes to underweight, overweight and obesity in young boys and girls.
It is quite well known that South Carolina sent four aristocrats to represent her in the 1787 Constitutional Convention. It is less well known that one of the four merited a listing in Burke's Peerage. In fact, while much has been written about Charles Pinckney, C. C. Pinckney, and John Rutledge, the fourth member of the delegation has been the subject of a few biographical sketches and virtually nothing more. And yet Pierce Butler was not an insignificant member of the delegation or of the Convention. Indeed, several positive claims to fame that can be established in his behalf suggest the need for a more realistic assessment of his role in the 1787 Convention. This paper is designed as a first step in that direction.
As part of a multi-wavelength study, we report on a 50 ks Chandra/ACIS observation of the Guitar Nebula, a bow shock nebula associated with the radio pulsar B2224+65. We see a “hot spot” at the tip of the bow shock. We also notice a “jet” of X-ray emission at position angle (PA) −69°. However, the proper motion of the pulsar and the axis of optical emission is at PA 52°.1. We discuss the resulting interpretations of the relativistic pulsar wind and the surrounding ISM.
Decorsin is an antagonist of integrin αIIb β3 and a potent platelet aggregation inhibitor. A synthetic gene encoding decorsin, originally isolated from the leech Macrobdella decora, was designed, constructed, and expressed in Escherichia coli. The synthetic gene was fused to the stII signal sequence and expressed under the transcriptional control of the E. coli alkaline phosphatase promoter. The protein was purified by size-exclusion filtration of the periplasmic contents followed by reversed-phase high-performance liquid chromatography. Purified recombinant decorsin was found to be indistinguishable from leech-derived decorsin based on amino acid composition, mass spectral analysis, and biological activity assays. Complete sequential assignments of 1H and proton bound 13C resonances were established. Stereospecific assignments of 21 of 25 nondegenerate β-methylene groups were determined. The RGD adhesion site recognized by integrin receptors was found at the apex of a most exposed hairpin loop. The dynamic behavior of decorsin was analyzed using several independent NMR parameters. Although the loop containing the RGD sequence is the most flexible one in decorsin, the conformation of the RGD site itself is more restricted than in other proteins with similar activities.
from
Section 6
-
Behavioural interventions in medicine
By
M. Friedman, Harvard University Health Services,
C. E. Thoresen, Harvard University Health Services,
J. J. Gill, Harvard University Health Services,
D. Ulmer, Harvard University Health Services,
L. H. Powell, Harvard University Health Services,
V. A. Price, Harvard University Health Services,
B. Brown, Harvard University Health Services,
L. Thompson, Harvard University Health Services,
D. D. Rabin, Harvard University Health Services,
W. S. Breall, Harvard University Health Services,
E. Bourg, Harvard University Health Services,
R. Levy, Harvard University Health Services,
T. Dixon, Harvard University Health Services
Edited by
Andrew Steptoe, St George's Hospital Medical School, University of London,Jane Wardle, Imperial Cancer Research Fund, London
One thousand thirteen post myocardial infarction patients were observed for 4.5 years to determine whether their type A (coronary-prone) behavior could be altered and the effect such alteration might have on the subsequent cardiac morbidity and mortality rates of these individuals. Eight hundred sixty-two of these individuals were randomly assigned either to a control section of 270 participants who received group cardiac counseling or an experimental section of 592 participants who received both group cardiac counseling and type A behavioral counseling. The remaining 151 patients, serving as a “comparison group,” did not receive group counseling of any kind. Using the “Intention-to- Treat” principle, we observed markedly reduced type A behavior at the end of 4.5 years in 35.1% of participants given cardiac and type A behavior counseling compared with 9.8% of participants given only cardiac counseling. The cumulative 4.5-year cardiac recurrence rate was 12.9% in the 592 participants in the experimental group that received type A counseling. This recurrence rate was significantly less (p< 0.005) than either the recurrence rate (21.2%) observed in the 270 participants in the control group or the recurrence rate (28.2%) in those of the comparison group not receiving any special treatment. After the first year, a significant difference in number of cardiac deaths between the experimental and control participants was observed during the remaining 3.5 years of the study. Overall, the results of this study demonstrate for the first time, within a controlled experimental design, that altering type A behavior reduces cardiac morbidity and mortality in post infarction patients. (AM HEART J 1986; 112:653).
Persons who exhibited an emotional syndrome characterized by a continuously harrying sense of time urgency and easily aroused freefloating hostility (i.e. type A behavior pattern) were observed in 1959 to have a sevenfold greater prevalence and in 1975 a significantly greater incidence of clinical coronary heart disease (CHD) than persons not exhibiting these two emotional components (i.e., type B persons).
Ever since this observed associational relationship between the presence of type A behavior and the prevalence and incidence of clinical CHD, hundreds of studies have been designed to investigate further the nature of this association.
In this research note I seek to determine whether a significantly predicting social background model for analyzing the votes of Supreme Court justices is time-bound. I argue that an affirmative result poses serious questions for past uses of such models, none of which has controlled for the possibility that time is a confounding variable. A model that significantly predicted the votes of the justices in the Court's 1903–1968 terms was constructed. Analysis with this model for two periods—from 1903 to 1935, and from 1936 to 1968—established that the model was not timeneutral. Appropriate theoretical implications are drawn.
In the period from 1947 to 1976, the United States Supreme Court has denied certiorari in more than half the cases involving conflict with Supreme Court precedent or intercircuit conflict. In both instances, the denial rate has been higher in the Burger Court than in the Vinson and Warren Courts and denial has been greater for intercircuit conflict cases than for cases in which the ruling in the lower court was in conflict with one or more Supreme Court precedents. When conflict was conceptualized as a predictor of decision and examined along with federal government as petitioning party, economic issues, and civil liberty issues, it was found to have 4 to 7 times the predictive power of the other variables combined for the Vinson and Warren Courts. For the Burger Court, the petitioning party variable was found to be a better predictor than conflict, but conflict was a much better predictor than the subject variables. Discriminant function models using the four predictor variables were able to account for up to 36.9% of the variance in the Supreme Court's certiorari decisions, almost all of which was the result of the contributions made by the conflict and party factors.
This paper presents preliminary findings from a study designed to fill a gap in political scientists' knowledge about the extent to which the Supreme Court grants or denies plenary review when conflict with one or more of its precedents is claimed. The findings are that the presence of conflict promoted the granting of review between 1961 and 1976, including the Warren Court terms (1961–68), even in the face of controls for litigant status, civil liberty issues, and constitutional issues, but that it was a poorer predictor during the Burger Court terms (1969–76).
In making review decisions, Supreme Court justices are predisposed to support underdogs and upperdogs. disproportionately but, also, are motivated to hide any "bias" that may be at work in determining votes.
In balancing these two values, justices may be expected to vote their "bias" more frequently (1) when that vote will determine outcome, and (2) when the "bias" will be harder to detect. The latter goal may be served by voting the "bias" more frequently in close cases and less frequently otherwise.
In an analysis of the voting patterns of five justices in the decade 1947–56, I found that two liberal and two conservative justices conformed to these expectations. A fifth, or control justice, defined as neither liberal nor conservative, did not pattern his votes in the manner predicted for liberals and conservatives. This relationship held when four projected intervening variables were controlled individually and collectively.
In making his televised announcement on the nominations of Lewis Powell and William Rehnquist for seats on the Supreme Court, Richard Nixon observed that he was merely fulfilling a campaign promise. For, he said: “… during my campaign for the Presidency, I pledged to nominate to the Supreme Court individuals who shared my judicial philosophy which is basically a conservative philosophy. … As a judicial conservative, I believe some Court decisions have gone too far in the past in weakening the peace forces as against the criminal forces in our society” (New York Times, 1971: 24C). In 1968, Mr. Nixon said: ”We need more strict constructionists on the highest court of the United States. In my view, the duty of a Justice of the Supreme Court is to interpret the law, not to make the law, and the men I support will share that view“ (U.S. News & World Report, 1968: 42).