To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Patients undergoing craniotomy experience a higher risk of seizures in the ensuing months. Consensus is lacking regarding the appropriate timeframe for safe return to driving following craniotomy in patients not otherwise limited by neurological deficits or a history of epilepsy.
Methods:
The Canadian Neurosurgery Research Collaborative (CNRC) distributed an anonymous, voluntary, electronic cross-sectional survey via SurveyMonkey to Canadian neurosurgeons. The survey comprised 16 questions designed to assess practice variations regarding recommendations for return to driving following craniotomy, stratified according to pathological diagnosis.
Results:
Forty-eight Canadian neurosurgeons responded to the survey. Driving recommendations varied greatly, with most surgeons recommending return to driving within one month of the craniotomy. The rationale behind these restrictions varied widely, consistent with the lack of evidence-based data to guide decision-making.
Conclusion:
This study emphasizes the lack of standardized practices regarding return to driving recommendations for patients undergoing craniotomy without prior seizures. Development of national return to driving guidelines would assist Canadian clinicians in making informed decisions regarding the optimal timeframe for the safe return to driving.
Patients undergoing craniotomy experience a higher risk of seizures in the ensuing months. Consensus is lacking regarding the appropriate timeframe for safe return to driving following craniotomy in patients not otherwise limited by neurological deficits or a history of epilepsy.
Methods:
We performed a systematic literature review on driving recommendations post-craniotomy. We then performed a scoping review on the risk of seizure post-craniotomy and used risk calculations and accepted risk thresholds from the epilepsy literature to develop an evidence-based approach to driving recommendations post-craniotomy.
Results:
The systematic review of driving recommendations revealed national guidelines (the United Kingdom, New Zealand, Australia). We transposed risk calculations and accepted risk thresholds from the epilepsy literature (accident risk ratio [ARR] < 2; chance of occurrence of a seizure in the next year < 20%) to patients who undergo a craniotomy. Using data from a large meta-analysis of seizure risk post-craniotomy, we calculated ARRs for various underlying pathologies at different postoperative timepoints and compared them with accepted risk thresholds from the epilepsy literature. We determine that patients who undergo a craniotomy for a higher-risk condition (like high-grade glioma) may resume driving after at least 1 month without seizure, whereas those patients undergoing a craniotomy for lower-risk conditions (like infratentorial pathology) may resume driving without consideration for the risk of seizure.
Conclusion:
This systematic review of the literature and evidence-based approach to risk threshold calculations derived from the epilepsy literature provides a preliminary framework to guide clinicians regarding recommendations for return to driving following craniotomy.
Cerebrospinal fluid diversion via ventriculoperitoneal (VP) shunting is the mainstay treatment for hydrocephalus. Traditionally, neurosurgeons place the abdominal catheter through abdominal incision, which has become an efficient and standardized technique. This approach carries a 10–30% complication rate, including infection, catheter obstruction, misplacement, hemorrhage and post-operative pain. Laparoscopic assistance (LA) is an emerging alternative to mini-laparotomy, with potential benefits including reduced distal catheter malplacement and shorter operative times. Most investigations on LA are limited to single centers, with no data from Canada. This study aims to identify practice patterns in VP shunting within a Canadian context.
Methods:
Practicing Canadian neurosurgeons were surveyed using a modified Delphi methodology. The survey was distributed to practicing neurosurgeons via the Canadian Neurosurgical Society and the Canadian Neurosurgery Research Collaborative.
Results:
Across two rounds, 36 neurosurgeons participated, representing all provinces with academic neurosurgical centers. Consensus was reached on five out of eight topics. Findings revealed that 65.5% of respondents had experience with LA, and 93% believed it reduced distal catheter malposition. Infection (77.8%), distal catheter obstruction (82.9%) and proximal obstruction (69.4%) were identified as the most common complications, each occurring in up to 10% of cases. In total, 71% anticipated eventual reduced operative times with increased LA experience.
Conclusion:
Canadian neurosurgeons did not identify major barriers to LA beyond personal preference. LA is expected to improve distal catheter placement, though its broader benefits remain uncertain. Patient comorbidities were considered a greater risk factor for complications than surgical technique alone.
The chapter explores the evolution and future of invasive monitoring in epilepsy surgery, emphasizing the impact of technological advancements and conceptual shifts. The goal of epilepsy neurosurgery is to enhance brain function by precisely targeting and removing malfunctioning brain areas. Due to the brain’s complexity, detailed and accurate information about each patient’s condition is vital. Invasive monitoring, a diagnostic procedure involving the placement of recording electrodes in the brain, provides critical data for crafting tailored surgical strategies. Historically, the use of invasive monitoring evolved with the development of electrocorticography (ECoG) and stereotactic electroencephalography (sEEG). Early implementations relied on ictal symptoms and non-invasive techniques such as EEG, but advancements in electrode placement, notably by Jean Talairach and subsequent pioneers, enabled precise localization of seizure onset zones (SOZ). The regional divide saw North America favoring subdural grids, while Europe preferred sEEG, leading to a revolution in epilepsy surgery practice. Currently, sEEG dominates due to its ability to record deep brain structures and offer comprehensive network analysis. This shift is bolstered by innovations such as robot-assisted stereotaxy and MRI-guided laser therapy. The chapter concludes by highlighting the potential future directions, including enhanced computational analysis, Bayesian approaches, and artificial intelligence, which promise to refine surgical planning and improve patient outcomes.
Neurological disorders are the leading cause of disability worldwide. Restoring function through the modulation of brain networks has been a cornerstone in the field of functional restoration. Deep brain stimulation (DBS) along with neuroprosthetics such as cochlear implants have significantly improved the quality of life for patients with functional restoration. However, there remains a large population of patients who cannot benefit from existing approved medical technologies. Brain–machine interfaces (BMI) show great promise in addressing the unmet need in diagnostic and functional needs for patients with neurological disorders and disabilities. To date, more humans have received clinical benefit from the Utah Array than from any other BMI, but this also had several limitations. Recent advances in BMI address these limitations, showing improvements in invasiveness, longevity, signal quality, and usability. This chapter provides an overview of BMI and discusses the evolving technology in the field of BMI, which provides a novel dimension to the existing neurosurgical armamentarium modulating neurological function beyond the conventional neurosurgical treatment.
The concept of Neurosurgery is arguably the oldest of surgical specialties. It has evolved in scope and sophistication in bursts over many centuries – driven by the available knowledge, technologies, needs, and the courage of practitioners to move the concept forward. Concurrently, the computer has become a unifying neurosurgical tool, allowing for enormous expansion of novel concepts of treatment accessible. In this sense, the “Neurosurgeon” of the future will be in constant evolution with such technology – adapting according to the environmental demands of a growing and multifaceted field. In this chapter, we explore the role of the Neurosurgeon today and what the future may hold.
Imaging has become essential to the field of neurosurgery and has evolved significantly since the invention of the X-ray in 1895. Following the introduction of the X-ray, imaging techniques including ventriculography, myelography, encephalography and angiography revolutionized the field of neurosurgery by allowing for the visualization of intracranial and spinous structures not visible by clinical examination. Significant continued rapid advancements and implementation of new imaging techniques have occurred since the introduction of cross-sectional imaging, including CT and conventional MRI techniques. In recent years, imaging has become increasingly more sophisticated with the advent of DTI, functional imaging, radiogenomics, high-field strength MRI, and glymphatic imaging. Though imaging is already essential for diagnosis, presurgical planning, intra-operative guidance, post-surgical guidance, and surveillance, the possibilities offered by new imaging techniques will likely make neuroimaging even more central to the care and management of neurosurgical patients in the future. Our chapter provides a brief review of the history of available techniques and advanced imaging methods.
Advances in molecular engineering, materials science, and other key fields has afforded the ability to bring newly minted nano-scale science to the bedside in all medical specialties, notwithstanding neurosurgery. Modern neurosurgery has implemented a handful of available nanotechnologies to enhance clinical practice. However, the current implementation of nanotechnology has barely scratched the surface of its widespread potential application in neurosurgery, neuroimaging and neuro-oncology. Most of the technology is still relegated to the laboratory, but many recent developments have made these technologies more clinically applicable. Nanoparticles are increasingly used for drug delivery across a wide variety of neurologic disorders, new radiographic contrast agents and in vivo cell labeling, and numerous enhancements in neurosurgical hardware, including batteries, microelectrodes, spinal instrumentation and endovascular equipment. We still have much to learn about the clinical use of these technologies and the upcoming hurdles, such as cost, that may still limit technology as they become ready for everyday use. The future of nanotechnology in neurosurgery is happening now and will bring incredibly exciting and impactful applications to patient care.
The chapter highlights the importance of precision, planning, and rehearsal in neurosurgery due to the brain’s intricate structure. Advances in technology, such as augmented reality (AR) and virtual reality (VR), have revolutionized surgical planning, training, and execution. These technologies offer detailed 3D visualizations and interactive simulations, allowing surgeons to practice and refine their skills in a controlled environment. VR systems enable customized patient-specific models, enhancing pre-operative planning and interdisciplinary collaboration. AR overlays digital information onto the real world, providing real-time guidance during surgeries. The integration of AI, haptic feedback, and robotics further improves precision and outcomes, potentially transforming neurosurgical procedures and training.
Laser interstitial thermal therapy (LITT) involves the utilization of laser light energy and its photothermal properties when interacting with tissue for the treatment of various pathologies via the induction of hyperthermia and coagulation. Current neurosurgical applications of LITT include treatment of metastatic in-field recurrence, primary brain tumors, epilepsy, movement disorders, psychiatric disorders, pain syndromes, and spine tumors. Here we explore the basic principles of LITT and its current applications within neurosurgery. We then discuss the potential directions in which LITT may progress as a treatment modality, both as a stand-alone procedure and in conjunction with other adjunct interventions.
Neurosurgery has always been at the forefront of adopting innovative technologies and this may easily be explained by the unique demands imposed on surgeons when operating in the brain and spine. Augmented reality (AR) has emerged as a promising technology in neurosurgery, aiming to link the digital and physical worlds to enhance clinical practice and education. This review explores the evolution of AR in neurosurgery, from a modest optical technology inception to a digitally enhanced plethora of mixed reality media, and how widespread adoption has been hindered by technical limitations. Various approaches to displaying AR as well as requirements for future-proof patient digital models are discussed. Challenges associated with updating models intra-operatively and the need for precise tracking of the physical environment are also reviewed. The chapter concludes with the authors’ vision for overcoming these technical hurdles, which will be essential for realizing the full potential of AR in neurosurgical practice.
Introduction: Razors were being used for pre-operative hair removal in our Institute. As per international guidelines recommending the use of surgical clippers, we opted to study the effects of two pre-operative skin preparations in our Neurosurgical centre Objectives:Primary; Pre auditing period -Assess knowledge and skill in usage of Razor/Clipper as preoperative skin preparation methods, Provide training on Clipper method and assess the knowledge /awareness on merits and demerits of both methods, To implement the Clipper method as against Shaving Secondary ; Post auditing period -Investigate the efficacy and safety of clippers versus razors, on variety of biophysical parameters and Surgical Site Infection (SSI) Methods : PICO questions ; Population: Adult patients undergoing any type of surgical procedure, Intervention: Hair removal, Comparator: Different methods of Hair removal, Outcomes: Biophysical parameters and SSI •Target population: Sixty adult patients undergoing neurosurgical procedures. •Subjects: 30 each subjected to shaving and clipper methods •Pre and Post assessment of on 25 parameters /sub-parameters •Analysis by MS-Excel and SPSS. Results:•Preoperative -Prior skin injuries and/or reactions; adequacy of hair removal •Complete hair removal : 30 (100%) in the clipper group versus 3 (10%) by shaving (p = 0.0001). •30 mins after hair removal ; significantly less skin issues in the clipper group •Post operative - Skin injuries in 20 (66.6%) of the razor and none in the clipper group. •SSI - Two (6.6%) in the razor and none in the clipper group. Conclusions: The assessment showed that shaving leads to partial hair removal increasing the scores for skin issues, significant association between preoperative skin injuries and SSI, implying inverse correlation with the clipper method. This study provides insights into significance of among other biophysical parameters underscoring adoption of clipper as the standard practice for preoperative hair removal, in our setting thus enhancing patient safety.
Access to neurosurgical care is essential for addressing elective and non-elective neurosurgical conditions. Disparities in healthcare access in Canada persist, disproportionately affecting rural, Indigenous and socioeconomically disadvantaged populations. This scoping review sought to identify barriers and facilitators influencing neurosurgical access to care while highlighting gaps in the literature on equity-deserving groups.
Methods:
A systematic literature search of articles published from January 2000 to August 2024 was conducted using MEDLINE, EMBASE, Cochrane Library, PsycINFO and Scopus. Gray literature from governmental and non-governmental organizations was also reviewed. Of 1400 identified records, eight studies met the inclusion criteria. These studies were analyzed using inductive coding and thematic analysis to explore socioeconomic, geographic, racial, gender-based and cultural barriers.
Results:
Four major themes emerged: delays in access, alternative healthcare options, policy barriers and communication and coordination. Barriers including transportation gaps, socioeconomic inequities and systemic discrimination were prominent, especially for rural and Indigenous populations. Facilitators like telehealth and improved inter-hospital coordination showed promise but were hindered by infrastructure limitations and cultural misalignments. Few studies addressed the intersectionality of these barriers, highlighting gaps in understanding their cumulative impact.
Conclusion:
The findings in this review underscore the need for systemic reforms, including equitable resource allocation, digital infrastructure expansion and culturally congruent care. Addressing these barriers is critical to ensuring timely and equitable neurosurgical care across Canada. Future research should prioritize intersectional approaches to better understand overlapping access challenges and evaluate the efficacy of tailored interventions.
Neurosurgery is a demanding specialty, and a trainee’s exposure to its tenets is usually achieved through residency. Medical students only access neurosurgical knowledge via brief stints in clerkships/electives and often lack mentorship and early exposure. This study sought to investigate the varying expectations about neurosurgical training held by Canadian medical students, with the goal of determining the impact of early exposure through educational opportunities and mentorship in developing interest and familiarity in the field.
Methods:
A cross-sectional study across Canada was conducted where students were provided with a 35-point questionnaire pertaining to mentorship, educational opportunities and interests regarding neurosurgery through REDcap. Questions were open-ended, closed-ended (single choice) or five-point Likert scale (matrix format). Interest in pursuing neurosurgery was selected as the primary outcome of this study and was dichotomized into high or low interest. Predictors of interest were determined using multivariable logistic regressions.
Results:
A total of 136 students from 14 accredited Canadian medical schools responded to the study. Most (55.9%) had prior exposure, and the most commonly reported deterring factors were work–life balance (94.5%) and family (84.6%). Predictors of interest included participation in relevant case-based discussion (OR = 2.644, 95% CI [1.221–5.847], p = 0.015) and involvement in neurosurgical research encouraged by home institution (OR = 1.619, 95% CI [1.124–2.396], p = 0.012).
Discussion
Future efforts to improve student interest should focus on early exposure to the field such as developing pre-clerkship neurosurgical electives or medical student groups focused on neurosurgery.
Chronic subdural hematoma (cSDH) is a common condition, especially in the older population, and causes considerable morbidity. Recently, middle meningeal artery embolization (MMAE) has shown promise as a minimally invasive intervention for cSDH by disrupting the flow to the hematoma neomembranes and thus reducing recurrence.
Methods:
We performed a systematic review of the literature using PubMed/Medline and Google Scholar to identify studies reporting on MMAE for cSDH over the past 30 years. After screening 4103 articles and reviewing 600 full-text studies, 176 studies were selected, including case reports, case series, retrospective and prospective studies and randomized controlled trials. Patient demographics, embolic agents used, frequency, type and severity of complications, hematoma recurrence and need for repeat surgery were extracted from the included studies.
Results:
Our analysis included 9780 patients (75.9% male), with mean/median ages ranging from 62.1 to 82.5 years. MMAE-related complications were reported in approximately 3%. Procedure-related neurological complications were the most frequent, followed by systemic complications, access site, non-procedure-related neurological complications, procedure-linked vascular complications specific to MMA and miscellaneous complications. Hematoma recurrence was reported in 6%, and repeat or rescue surgery was necessary in 6.1%. These results are consistent with major clinical trials evaluating MMAE safety and efficacy in cSDH.
Conclusion:
Based on current published literature, MMAE appears to be an effective and overall safe treatment option for cSDH. Complications, although infrequent, can occur, and some of these are disabling. Meticulous pre-procedural planning and imaging are essential to reduce the risk of complications.