We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Large temporal fluctuations or oscillations in cellular states are widely observed in biological systems, for instance, in neural firing, circadian rhythms, and collective motion of amoebae. These phenomena arise from the interplay between positive and negative feedback mechanisms, as discussed in previous chapters. In this chapter, we focus on such dynamic changes in cellular states. Using trajectories of oscillatory dynamics in phase planes such as the Brusselator, we provide detailed explanations of conditions for oscillation through the use of nullcline and Jacobian matrix analyses. We confirm the existence of two mechanisms: the activator-inhibitor system and the substrate-depletion system. Furthermore, we extensively introduce the Hodgkin–Huxley equations concerning membrane potential and excitability, which represent a significant milestone in the fields of biophysics, theoretical biology, and electrophysiology. Through quantitative comparison with experimental data, we elucidate the mechanisms underlying its dynamics, which are explained by the reduction of variables leading to the FitzHugh–Nagumo equations.
To understand life phenomena, we must consider form, structure, organization, motion, and the roles they play in “living” functions. This book explores such elements through mathematical methods. Beginning with an overview of dynamical systems and stochastic processes, the chapters that follow build on experimental advances in quantitative data in cellular processes to demonstrate the applications of these mathematical methods to characterize living organisms. The topics covered include not only cellular motions but also temporal changes in metabolic components, protein levels, membrane potentials, cell types, and multicellular patterns, which are linked to functions such as cellular responses, adaptation, and morphogenesis. This book is intended for undergraduates, graduates, and researchers interested in theory and modeling in biology, in particular cell, developmental, and systems biology, also those in the fields of mathematics and physics who are interested in these topics.
The exact mechanisms underlying dysfunction of the basal ganglia that lead to Parkinson’s disease (PD) remain unclear. According to the standard model of PD, motor symptoms result from abnormal neuronal activity in dysfunctional basal ganglia, which can be recorded in human basal ganglia structures as functional neurosurgery for PD provides a unique opportunity to record from these regions. Microelectrode and local field potential recordings studies show alterations exist in basal ganglia nuclei as well as in the motor thalamus. Lesioning or stimulation of the basal ganglia results in significant improvement of PD symptoms, supporting the view that basal ganglia–thalamocortical circuits abnormality is important in parkinsonism generation. Different patterns of oscillatory neuronal activity plus changes in firing rate are associated with different parkinsonian motor subtypes. We present recordings of basal ganglia activity obtained with microelectrode recordings in parkinsonian patients, providing pathophysiology insight.
Oscillations between members of flavoured, electrically neutral meson pairs and the CP violation are phenomena strictly connected with the mixing. However, CP is more general, having been observed also in the decay of charged mesons.
CP violation was first observed in the neutral K system. We see the states of definite strangeness, those of definite CP and those with definite mass and lifetime. The oscillation between the former states, the mathematical expressions and the experimental evidence.
The oscillations and CP violation in the B0 system, and the beautiful experimental results obtained at dedicated high-luminosity electron–positron colliders, the ‘beauty factories’. Beauty physics at the dedicated experiment LHCb at LHC, in particular for the B0, that is not accessible to beauty factories. Examples of CP violation in B0. The recent discovery of CP violation in the charm sector.
How the many different measurements can be put together to test the SM with the unitary triangle.
The effect of tube depth, the separation distance between the tube and nozzle exit, and the nozzle pressure ratio on the characteristics of the flow coming out of the Hartmann tube was studied experimentally. The configuration used in this work consists of an underexpanded sonic jet emanating from a convergent nozzle directed into a closed-ended cylindrical tube of the same diameter (D) as the nozzle exit. The nozzle was operated at two levels of underexpansion corresponding to nozzle pressure ratio (NPR) 3 and 5. The distance (S) from nozzle exit and tube inlet was varied from 0.4D to 4D. Discrete high-amplitude tones (the jet regurgitant, JRG) were produced, only at certain (periodic) intervals (near the shock-cell terminations) of spacing for NPR 3, while for NPR 5 the JRG tones are produced at all points beyond the first shock-cell. For locations other than these, high-frequency tones (screech mode) were observed. The connection between the jet structure and operating modes revealed that the location of standoff shock ahead of the tube with respect to the jet structure plays a dominant role in the observed ‘modes’ rather than the nozzle tube separation. The results reveal that the frequency response of longer tubes in JRG mode approaches their quarter wave frequencies. The high-frequency oscillations observed in the screech mode showed independency with cavity (pipe) depth, contrary to the available literature, the transition between ‘different modes’ oscillation is a function of cavity depth.
This study analyzed the Doppler shift in the solar spectrum using the Interface Region Imaging Spectrograph (IRIS). Two types of oscillations were investigated: long period damp and short period damp. The researchers observed periodic perturbations in the Doppler velocity oscillations of bright points (BPs) in the chromosphere and transition region (TR). Deep learning techniques were used to examine the statistical properties of damping in different solar regions. The results showed variations in damping rates, with higher damping in coronal hole areas. The study provided insights into the damping behavior of BPs and contributed to our understanding of energy dissipation processes in the solar chromosphere and TR.
I ask in this chapter how embodied memories of violence and survival are captured through the various sensory reconstructions of war as a sensuous world of bodily transgressions. War affects a person’s sensibilities through the engendering of a shift in sense perception owing to unexpected turns of events. I consider how a repertoire of different genres of social texts about war and violence – from songs, letters, and poetry, to autobiographies, oral histories and others – form rich and sensuous repositories. These texts undergird how multiple facets and first-hand experiences of horror and disbelief are enacted through sensory modalities that either work individually or intersectionally. As much as the sensory provide vital clues for what might happen next – in one’s home, in the prison, or at a concentration centre – the sensory also strikes fear and anxiety on what the next course of action might be. By drawing upon ontological security theory, I show how these transpire within possible or potential recourse in differing contexts of precariousness. The senses therefore serve as a potent catalyst as they both incite fear and insecurity, but also latently security and some stability as they provide cues and information for social actors.
This paper consists of three parts: First, letting $b_1(z)$, $b_2(z)$, $p_1(z)$ and $p_2(z)$ be nonzero polynomials such that $p_1(z)$ and $p_2(z)$ have the same degree $k\geq 1$ and distinct leading coefficients $1$ and $\alpha$, respectively, we solve entire solutions of the Tumura–Clunie type differential equation $f^{n}+P(z,\,f)=b_1(z)e^{p_1(z)}+b_2(z)e^{p_2(z)}$, where $n\geq 2$ is an integer, $P(z,\,f)$ is a differential polynomial in $f$ of degree $\leq n-1$ with coefficients having polynomial growth. Second, we study the oscillation of the second-order differential equation $f''-[b_1(z)e^{p_1(z)}+b_2(z)e^{p_2(z)}]f=0$ and prove that $\alpha =[2(m+1)-1]/[2(m+1)]$ for some integer $m\geq 0$ if this equation admits a nontrivial solution such that $\lambda (f)<\infty$. This partially answers a question of Ishizaki. Finally, letting $b_2\not =0$ and $b_3$ be constants and $l$ and $s$ be relatively prime integers such that $l> s\geq 1$, we prove that $l=2$ if the equation $f''-(e^{lz}+b_2e^{sz}+b_3)f=0$ admits two linearly independent solutions $f_1$ and $f_2$ such that $\max \{\lambda (f_1),\,\lambda (f_2)\}<\infty$. In particular, we precisely characterize all solutions such that $\lambda (f)<\infty$ when $l=2$ and $l=4$.
where $(p(n))$ is a sequence of non-negative real numbers, $(\tau (n))$ is a sequence of integers such that $\tau (n)< n$ for$\ n\in \mathbf {N},\,$and$\ \lim _{n\rightarrow \infty }\tau (n)=\infty.$ Under the assumption that the deviating argument is not necessarily monotone, we obtain some new oscillation conditions and improve the all known results for the above equation in the literature, involving only upper and only lower limit conditions. Two examples illustrating the results are also given.
Sufficient conditions are obtained for the oscillation of a general form of a linear second-order differential equation with discontinuous solutions. The innovations are that the impulse effects are in mixed form and the results obtained are applicable even if the impulses are small. The novelty of the results is demonstrated by presenting an example of an oscillating equation to which previous oscillation theorems fail to apply.
Chapter 2 starts by analysing free and forced oscillations in a simple mechanical system, and the method of complex representation of sinusoidal oscillation is introduced, including phasor diagram in the complex plane. Moreover, the concepts of active and reactive power for such a system are introduced. Then the method of state-space analysis is introduced and applied to a linear system. Further, the delta 'function' and other related distributions, as well as Fourier analysis, are introduced and applied to linear systems. Moreover, causal and noncausal systems are considered, as well as Kramers–Kronig relations and the Hilbert transform.
Chapter 1 mentions some previous books on ocean waves, and how the present book is different and serves as a source of supplementary information, which is mainly concerned with the utilisation of the energy of ocean waves. Then a short summary is given for each of the other chapters of the book.
Referring to a simple illustration, a verbal explanation is given by the essential, but perhaps paradoxical, statement that to absorb wave energy from a wave by means of an oscillating system, it is required that the system radiates a wave which interferes destructively with the incident wave. Then various mathematical relations are derived concerning the conditions for an oscillating body to remove energy from an incident wave. The mathematical conditions for wave-power absorption may be illustrated as a paraboloid-shaped 'island' on an infinite complex-plane 'ocean' surface. The top of this 'island' corresponds to maximum absorbed power. An additional matter is the optimum control of a wave-energy converter (WEC) body. Thus far, the WEC body's shape and oscillation mode have been taken into account, but not its physical size. The latter is an important parameter related to the cost of the WEC, when the Budal upper bound is explained and discussed. Another important phenomenon, related to the Keulegan–Carpenter number, is discussed, in relation to an example of a WEC body. In a final section of the chapter, a WEC body, oscillating in several modes of motion, is discussed.
Understand the interaction between ocean waves and oscillating systems with this useful new edition. With a focus on linear analysis of low-amplitude waves, you are provided with a thorough understanding of wave interactions, presented to be easily accessible to non-specialist readers. Topics covered include the background mathematics of oscillations, gravity waves on water, the dynamics of wave-body interactions, and the absorption of wave energy by oscillating bodies and oscillating water columns. Featuring new content throughout, including three new chapters on oscillating-body wave energy converters, oscillating water columns and other types of wave energy converters, and wave energy converter arrays, this book is an excellent resource for students, researchers, and engineers who are new to the subject of wave energy conversion, as well as those with more experience.
We investigate the Weibel instability (WI) in a dusty plasma which is driven to oscillation by the addition of dust grains in the plasma. Our analysis predicts the existence of three modes in a dusty plasma. There is a high-frequency electromagnetic mode, whose frequency increases with an increase in the relative number density of dust grains and which approaches instability due to the presence of dust grains. The second mode is a damping mode which exists due to dust charge fluctuations in plasma. The third mode is the oscillating WI mode. The dispersion relation and the growth rate of various modes in the dusty plasma are derived using the first-order perturbation theory. The effect of dust grain parameters on frequency and growth rate is also studied and reported.
We establish new oscillation criteria for nonlinear differential equations of second order. The results here make some improvements of oscillation criteria of Butler, Erbe, and Mingarelli [2], Wong [8, 9], and Philos and Purnaras [6].
be the Bessel operator on ℝ+ := (0,∞). We show that the oscillation operator 𝒪(RΔλ,∗) and variation operator 𝒱ρ(RΔλ,∗) of the Riesz transform RΔλ associated with Δλ are both bounded on Lp(ℝ+, dmλ) for p ∈ (1,∞), from L1(ℝ+, dmλ) to L1,∞(ℝ+, dmλ), and from L∞(ℝ+, dmλ) to BMO(ℝ+, dmλ), where ρ ∈ (2,∞) and dmλ(x) := x2λ dx. As an application, we give the corresponding Lp-estimates for β-jump operators and the number of up-crossings.
Post-traumatic stress disorder (PTSD) is often associated with attention allocation and emotional regulation difficulties, but the brain dynamics underlying these deficits are unknown. The emotional Stroop task (EST) is an ideal means to monitor these difficulties, because participants are asked to attend to non-emotional aspects of the stimuli. In this study, we used magnetoencephalography (MEG) and the EST to monitor attention allocation and emotional regulation during the processing of emotionally charged stimuli in combat veterans with and without PTSD.
Method
A total of 31 veterans with PTSD and 20 without PTSD performed the EST during MEG. Three categories of stimuli were used, including combat-related, generally threatening and neutral words. MEG data were imaged in the time-frequency domain and the network dynamics were probed for differences in processing threatening and non-threatening words.
Results
Behaviorally, veterans with PTSD were significantly slower in responding to combat-related relative to neutral and generally threatening words. Veterans without PTSD exhibited no significant differences in responding to the three different word types. Neurophysiologically, we found a significant three-way interaction between group, word type and time period across multiple brain regions. Follow-up testing indicated stronger theta-frequency (4–8 Hz) responses in the right ventral prefrontal (0.4–0.8 s) and superior temporal cortices (0.6–0.8 s) of veterans without PTSD compared with those with PTSD during the processing of combat-related words.
Conclusions
Our data indicated that veterans with PTSD exhibited deficits in attention allocation and emotional regulation when processing trauma cues, while those without PTSD were able to regulate emotion by directing attention away from threat.