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Edited by
Rebecca Leslie, Royal United Hospitals NHS Foundation Trust, Bath,Emily Johnson, Worcester Acute Hospitals NHS Trust, Worcester,Alex Goodwin, Royal United Hospitals NHS Foundation Trust, Bath,Samuel Nava, Severn Deanery, Bristol
Understanding the principles and implications of pressure measurement is vital in anaesthesia. Here, in a similar structure to previous chapters we outline the basic physical principles of pressure, the variety of ways that it can be measured in clinical practice and the relationships with other physical principles. There is then focussed material on blood pressure measurement, through invasive and non-invasive techniques, on resonance and damping in pressure measurement systems, and on the measurement of intracranial pressure. The chapter finishes by discussing cardiac output measurement in clinical practice.
Edited by
Rebecca Leslie, Royal United Hospitals NHS Foundation Trust, Bath,Emily Johnson, Worcester Acute Hospitals NHS Trust, Worcester,Alex Goodwin, Royal United Hospitals NHS Foundation Trust, Bath,Samuel Nava, Severn Deanery, Bristol
This chapter is focussed on the International Standard of Units (SI) and their relevance to anaesthesia. This is a common exam question and it is important to understand the relationship between base SI units and other derived units. The chapter relates pressure to force, and clarifies the different measures of pressure including how they can be interchanged.
The key question in mechanical ventilation is whether invasive or non-invasive is the option being applied to the individual patient. In order to answer this question, it is necessary to recognize the pathophysiology and understand which physiological system has failed and needs to be supported. In this chapter we outline the optimal treatment options for respiratory insufficiency type 1 and 2. The reader will be made familiar with the basic principles of non-invasive and invasive ventilation. The aim is to arbitrate an overview as well as basic flowchart for the treatments depending on which of the aforementioned respiratory insufficiencies are to be treated. The chapter also comprises a quick guide to the initial ventilator settings.
The current strategic environment can be characterised as a return to great power competition, centred on the Indo-Pacific region, within an environment of post-pandemic climate change. The ’region is in the midst of the most consequential strategic realignment since the Second World War’, and the confluence of these characteristics has resulted in a major step-change for Australia’s strategic policy and has significantly increased expectations of the Australian Defence Force. For the ADF, the force generation and force employment requirements to effectively shape, deter and respond within a ’competitive and contested’ region increase the demand signal on the force. For the Australian Army, accelerated warfare requires land forces ’to be ready to do more tasks, fight at all ranges, and enable the joint force in every domain’.
Manipulation is pervasive in our lives, yet it is not well understood. Specifically, we lack a wide philosophical theory of manipulation. Such a theory will successfully answer two main questions: a question about the precise meaning of “manipulation,” and a question about its moral status. Prior to presenting a novel theory of manipulation in the following chapters, Chapter 1 offers an overview of the state of the art of philosophical thinking on manipulation. The semantic field of manipulation is constructed by three main concepts: rational persuasion, deception, and coercion. Manipulation cannot, however, be understood adequately on the basis of any one of these concepts, and there is no good theory that accounts for manipulation using a combination of them. The chapter reviews the many difficulties left open by notable attempts to provide an account of the concept of manipulation. The criticisms of those attempts raise the deeper suspicion that perhaps manipulation is not to be captured by a definition at all.
ATO4 compounds are a class of oxides which includes the rare earth element (REE) bearing phosphates and arsenates, REEPO4 and REEAsO4. In this study, we have investigated the isothermal high-pressure and the isobaric high-temperature behaviour of natural samples of xenotime-(Y) (ideally YPO4), chernovite-(Y) (YAsO4) and monazite-(Ce) (CePO4) from the hydrothermal veins cropping out at Mt. Cervandone in the Western Italian Alps. Experimental data based on in situ X-ray diffraction (both single-crystal and powder techniques with conventional or synchrotron radiation) have allowed us to fit the unit-cell volumes and axial thermal and compressional evolution and provide a suite of refined thermo-elastic parameters. A comprehensive analysis of the role played by the crystal chemistry on the thermo-elastic response of these minerals is discussed, along with the description of the main crystal-structural deformation mechanisms for both the zircon (xenotime and chernovite) and monazite (monazite) structural types. Pressure-induced phase transitions of xenotime-(Y) and chernovite-(Y) are discussed and compared with previous literature data, whereas a change in the compressional behaviour of monazite-(Ce) at ∼18 GPa, involving an increase in the coordination number of the REE-hosting A site, is presented and discussed.
Half of all mental health problems start by the age of 15 and the teenage and young adult years are particularly difficult for girls with high and increasing rates of anxiety, depression and self-harm. Many different factors contribute, including social media, peer pressures, focus on appearance, friends, relationships, schoolwork and, as Everyone’s Invited has recently highlighted, personal safety. There is tremendous pressure to conform with the expectations of others. Attitudes to women and girls seem to have gone into reverse during the author’s lifetime. It is too simplistic to view the problems of young women as a simply a ‘lack of self-esteem’. The difficulties they face in society are consistently underestimated and not taken seriously. Fast access to therapy is crucial. Bullying must be addressed effectively. Sexist and mysogynistic attitudes in school must be challenged and, given the easy access now to pornography, the issues of consent should addressed head on by both parents and schools. Using the example of Everyone’s Invited, women and girls need to reach out and support each other. The personal is still political.
Of the two parallel lives, it is Hannibal who used an elected position to carry through political and economic reforms unwelcome to the ruling oligarchy, whereas Scipio was quiet and accepting of the status quo. A story that Hannibal was prosecuted after Zama is not believable. He urged acceptance of the peace terms after Zama, manhandling an opposing speaker; he apologized for this, pleading long absence from civil life. As elected ‘praetor’ (sufete), he antagonized powerful citizens. His summons of a ‘quaestor’ (financial official) was refused. Scipio, soon after, also had trouble with a recalcitrant quaestor. Hannibal’s main political reform was to end life tenure of the ‘judges’. Economically, perhaps using skills developed when managing the logistics of his Italian campaign, he calculated Carthage’s revenues and ended embezzlement. The unpopularity with the ruling class so generated, and Roman diplomatic pressure, caused him to flee permanently. Carthage’s second-century economy is evaluated.
The NHS, the great survivor of the post-war consensus, faced a period of considerable uncertainty. This chapter will examine if, and how, the Conservatives have changed the NHS in the face of economic pressures, technological advances, demographic change, changing expectations and the pandemic. Any analysis of the health policy of a government is incomplete without examining the wider state of social care and its relation to healthcare policy.
There are many different varieties of automatic weather stations (AWSs) available, and a huge range of different applications for them. This chapter suggests a structured approach to specifying AWS features to meet any particular requirement, provides a short guide to AWS products and services available (from consumer brands to sophisticated professional systems capable of unattended operation in remote areas) and offers guidance in selecting one or more options from the multiplicity of product offerings on the market.
The osmotic swelling of an n-butylammonium vermiculite in a 0.1 M solution of n-butylammonium chloride has been studied as a function of temperature and hydrostatic pressure by neutron diffraction. On application of a pressure of 1050 bar the vermiculite swelled macroscopically at 20°C, the c-axis spacing changing from 19.4 to 126 Å. The phase transition was completely reversible with respect to both pressure and temperature, and a complete study of the temperature-pressure phase diagram was made at pressures as high as 2000 bar. The heat capacity change with temperature across the swelling transition was measured at atmospheric pressure, and the enthalpy and entropy of the change from crystalline to osmotic phases were found to be, respectively, 5.2 J/g and 0.0183 J/K·g of dry clay. The combination of the entropy change with the gradient of the pressure-temperature phase boundary gave the volume change accompanying the transition. The total volume of the swollen phase was less than that of the crystalline phase plus the appropriate amount of solution, corresponding to a fractional decrease of about 0.1% in the water volume from bulk solution to between the plates.
The dehydration temperature of K-montmorillonite, obtained by ion exchange of a Na-mont-morillonite, was determined at pressures to 2 kbar, using high-pressure differential thermal analysis. Dehydration reactions were found at about 50° and 100°C above the liquid-vapor curve of water. At pressures above the critical point of water the dehydration temperatures increased only slightly. The temperature of the first dehydration reaction is 10°C higher than for Na-montmorillonite, indicating a slightly greater stability of the hydration shell around the potassium interlayer cation. The second dehydration reaction occurs at a slightly lower temperature. The data were used to determine the enthalpy of the dehydration ΔH(dh) and the bonding enthalpy of the interlayer water ΔH(iw) at 1 atm. The first dehydration reaction of the K-exchanged montmorillonite has a ΔH(dh) = 46.16 ± 0.06 kJ/mole and a ΔH(iw) = 7.8 ± 0.5 kJ/mole, whereas for the second reaction, ΔH(dh) = 56.7 ± 2 kJ/mole and ΔH(iw) = 19.8 ± 2 kJ/mole. These values compare with a ΔH(dh) = 46.8 ± 0.3 kJ/mole and a ΔH(iw) = 7.8 ± 0.5 kJ/mole for the first dehydration reaction of the Na-montmorillonite and a ΔH(dh) = 62.9 ± 2 kJ/mole and ΔH(iw) = 27.1 ± 2 kJ/mole for the second dehydration.
A high-pressure, high-temperature cell was used to monitor the basal X-ray powder diffraction spacing of Na-saturated Cheto montmorillonite in contact with NaCl solutions at temperatures as high as 200°C and hydraulic pressures as high as 6700 psi (456 bar). The 003 and 005 reflections were used to determine d(001) of the smectite. The montmorillonite, in 1 molal NaCl, exhibited a d(001) of 15.4 Å at room temperature and pressure and a d(001) of 15.6–15.7 Å under 500–2200 psi hydraulic pressure. The basal spacing of the clay in 5 molal NaCl was 15.2 Å and 15.33–15.45 Å at 1 bar and 750–6700 psi (53–456 bar), respectively. Because no changes in the basal spacing with increasing temperature to 200°C were detected in any of the experiments, this Na-smectite probably exists as a two-water-layer complex under diagenetic conditions.
The first part of this work is devoted to the study of higher derivatives of pressure functions of Hölder potentials on shift spaces with finitely many symbols. By describing the derivatives of pressure functions via the central limit theorem for the associated random processes, we discover some rigid relationships between derivatives of various orders. The rigidity imposes obstructions on fitting candidate convex analytic functions by pressure functions of Hölder potentials globally, which answers a question of Kucherenko and Quas. In the second part of the work, we consider fitting candidate analytic germs by pressure functions of locally constant potentials. We prove that all 1-level candidate germs can be realised by pressures of some locally constant potentials, as long as the number of symbols in the symbolic set is large enough. There are also some results on fitting 2-level germs by pressures of locally constant potentials obtained in the work.
Given the full shift over a countable state space on a countable amenable group, we develop its thermodynamic formalism. First, we introduce the concept of pressure and, using tiling techniques, prove its existence and further properties, such as an infimum rule. Next, we extend the definitions of different notions of Gibbs measures and prove their existence and equivalence, given some regularity and normalization criteria on the potential. Finally, we provide a family of potentials that nontrivially satisfy the conditions for having this equivalence and a nonempty range of inverse temperatures where uniqueness holds.
Studies of the paragenesis of authigenic illite in arkosic sandstones of various regions and ages have revealed that the illitization of kaolinite is an important reaction accounting for the formation of authigenic illite in sandstones during burial diagenesis. The illitization of kaolinite takes place at an intermediate burial depth of 3–4 km, where pressure can reach values of 100 MPa (≈ 1000 bars). The purpose of the present study was to analyze the effect of pressure on the rate of kaolinite illitization in alkaline conditions. Hydrothermal reactions were conducted on KGa-1b kaolinite in KOH solution at 300°C and under pressures of 500, 1000, and 3000 bars for 1 to 24 h. The visual examination of the X-ray diffraction (XRD) patterns indicated a notable influence of pressure on the reaction rate. Molar percentages of muscovite/illite formed at each time interval were calculated from the analysis of two diagnostic XRD peaks, representing the 060 reflections of kaolinite and muscovite/illite. The data were modeled to obtain the initial rate of conversion at each pressure. The results indicated that the initial rate of kaolinite to muscovite/illite conversion is one order of magnitude greater at 3000 bars than at 500 or 1000 bars. Comparison of these data with those in the literature show a faster conversion rate (several orders of magnitude) in an initially high-alkaline solution than in a near-neutral solution.
Einsteins field equations are derived and discussed. It is argued that the Einstein tensor is proportional to the energy-momentum tensor and the constant of proportionality is derived by demanding that Newton’s Universal Law of gravitation be recovered in the non-relativistic limit. The modification of Einstein's equations when a cosmological constant is introduced is also presented.
This chapter introduces the mechanical property of a fluid when it is at rest. In the absence of shear force, fluid is balanced between pressure force and body force. A universal differential equation is derived to describe the pressure distribution in a static fluid. This equation, can be called hydrostatic equilibrium equation, is the key to solve any fluid static problems. Two typical situations are then discussed as applications of the hydrostatic equilibrium equation, one is static fluid under the action of gravity, the other is fluid under the action of inertial forces. Differences and similarities of fluids and solids in the transfer of force are discussed in the end. Atmospheric pressure at different heights is calculated in the “Expanded Knowledge” section.
Hemorrhage control prior to shock onset is increasingly recognized as a time-critical intervention. Although tourniquets (TQs) have been demonstrated to save lives, less is known about the physiologic parameters underlying successful TQ application beyond palpation of distal pulses. The current study directly visualized distal arterial occlusion via ultrasonography and measured associated pressure and contact force.
Methods:
Fifteen tactical officers participated as live models for the study. Arterial occlusion was performed using a standard adult blood pressure (BP) cuff and a Combat Application Tourniquet Generation 7 (CAT7) TQ, applied sequentially to the left mid-bicep. Arterial flow cessation was determined by radial artery palpation and brachial artery pulsed wave doppler ultrasound (US) evaluation. Steady state maximal generated force was measured using a thin-film force sensor.
Results:
The mean (95% CI) systolic blood pressure (SBP) required to occlude palpable distal pulse was 112.9mmHg (109-117); contact force was 23.8N [Newton] (22.0-25.6). Arterial flow was visible via US in 100% of subjects despite lack of palpable pulse. The mean (95% CI) SBP and contact force to eliminate US flow were 132mmHg (127-137) and 27.7N (25.1-30.3). The mean (95% CI) number of windlass turns to eliminate a palpable pulse was 1.3 (1.0-1.6) while 1.6 (1.2-1.9) turns were required to eliminate US flow.
Conclusions:
Loss of distal radial pulse does not indicate lack of arterial flow distal to upper extremity TQ. On average, an additional one-quarter windlass turn was required to eliminate distal flow. Blood pressure and force measurements derived in this study may provide data to guide future TQ designs and inexpensive, physiologically accurate TQ training models.
Dia, para- and ferromagnetism of rocks and minerals correspond to the wide range of magnetic susceptibility. Atomistic models of dia- and paramagnetism are considered. The Langevin function describes magnetic saturation of paramagnetic particles, whose magnetic susceptibility depends on temperature according to the Curie–Weiß law. Ferromagnetism, antiferromagnetism, ferrimagnetism and canted antiferromagnetism are considered. Ferromagnetic minerals are characterized by magnetic domains whose boundaries experience Barkhausen jumps during magnetization-demagnetization. Magnetic domains are separated by Bloch walls. Koenigsberg’s ratio, i.e. the ratio of induced and remanent magnetizations, depends on the shape demagnetization factor a The concept of locking temperature based on the magnetization relaxation time is used to reconstruct paleomagnetic fields, i.e. in the case of magnetic stripes of mid-oceanic ridge basalts. Principles of chemical, pressure and detrital-remanent magnetization. Focus Box 10.1: Magnetic field of a small dipole. Focus Box 10.2: Brillouin function. Focus Box 10.3: Electron shells, orbitals and orbital hybridization. Focus Box 10.4: Extended Weiss model.