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Chapter 16 on Causation explores the challenges of proving causation in an interconnected system like the climate, where multiple actors contribute to the overall impacts. The authors highlight the significance of probabilistic approaches, recognising that establishing direct causation can be challenging due to the nature of climate change and the cumulative nature of greenhouse gas emissions. In their exploration of emerging best practices, the authors underscore the growing recognition among courts of the need for nuanced interpretations of causation requirements in climate litigation. They highlight innovative judicial strategies that utilise scientific evidence and expert testimony to assess the contribution of specific actors to climate impacts, even in the absence of direct causation. They emphasise the importance of interdisciplinary collaboration between legal and scientific experts to navigate the complexities of causation in climate cases. By incorporating and further developing these emerging best practices, courts can facilitate an accurate and fair distribution of responsibilities through the cases they adjudicate.
This chapter examines travel and communication in Late Antiquity, analysing the complexities of movement across the Roman and Byzantine worlds from the third to the eighth century. Rather than viewing this period as one of declining mobility, the chapter argues that travel remained vital, though its dynamics shifted due to political, economic and religious transformations. A major focus is on the infrastructure that supported travel, including roads, bridges, way stations and ports. The cursus publicus, the state-run courier system, is highlighted as a crucial mechanism for imperial communication and administrative efficiency. Trade networks, both maritime and overland, played a fundamental role in sustaining long-distance movement, with Mediterranean seaports, river transport and caravan routes facilitating commercial exchanges. Religious travel, particularly pilgrimage and episcopal councils, became increasingly significant after the rise of Christianity, with the movement of monks, clergy and pilgrims contributing to the spread of religious ideas and artistic traditions. The chapter also addresses migration, discussing the movements of soldiers, officials and entire populations in response to military campaigns, economic opportunities and political upheavals. In this way, this contribution demonstrates that mobility remained central to the late antique world, shaping social, economic and cultural interactions across the empire.
There is a clinical need to appropriately apply large language model (LLM)-based systems for use in infectious diseases. We sought to use LLM and machine learning for extracting antibiotic susceptibility from clinical microbiology free-text reports, allowing use for outbreak detection, increasing information gathering efficiency, and public health reporting.
This chapter discusses the evolution of pagan iconography in Late Antiquity, examining how depictions of traditional gods and rituals changed between 300 and 700 CE. It challenges earlier interpretations that associate this period with artistic decline, instead emphasising continuity and transformation in the representation of pagan themes across various media. Drawing on legal, literary, epigraphic and archaeological evidence, the chapter provides a comprehensive perspective on the artistic and religious landscape of the period. It discusses key examples such as the Arch of Constantine, which repurposed older sacrificial motifs, and later fourth-century artworks like the Symmachi ivory diptych, which continued to depict pagan sacrifices despite the growing influence of Christianity. The chapter also examines the selective destruction of pagan imagery, particularly the mutilated reliefs from the Aphrodisias Sebasteion, demonstrating how sacrificial depictions were specifically targeted. The chapter concludes by noting that while sacrificial iconography faded, other pagan motifs – especially those associated with gods like Dionysus and Venus – remained prevalent in mosaics, silverware and textiles. This enduring presence underscores the adaptability of pagan imagery, which continued to influence artistic traditions long after the fall of the Roman Empire.
Two networks transformed the early modern world. The first was the Iberian network of discoverers and conquerors that helped usher in an age of European world domination and colonialism. The second was facilitated by a new technology, printing, which helped unleash the huge religious and political disruption we know as the Reformation. What Niall Ferguson describes as a “religious virus that came to be known as Protestantism” disrupted an ancient ecclesiastical hierarchy, fractured into many pieces Europe’s Catholic Christianity, and ushered in a long era of violent conflict. This chapter investigates religious networks within the Lutheran, Reformed, and Radical wings of the Reformation and highlights the formation, evolution, suppression, and ultimate survival of the Jesuit Order as a classic transnational network within Catholic Christianity.
Chapter 16 of DYB introduces a range of relief policies to succour the victims of natural disasters that Qiu Jun considers should be developed by the Ming state. His references go back to the Rites of Zhou and include a significant amount of Tang and Song precedents. He particularly insists on preparedness measures and on the pre-eminent role of the state to store the surpluses produced by society and redistribute them in years of famine – hence, for example, his reservations regarding public granaries run by local notables – and, more generally, to preserve the stability of local communities confronted with subsistence crises. If Qiu’s recommendations do not seem to have had much impact, if any, on Ming relief policies, several of them anticipate the setting up of a centrally controlled and fairly efficient system of famine relief under the Qing.
This chapter examines the production and significance of early Christian sarcophagi, emphasising their role in the development of Christian iconography and funerary practices. It explores a wide range of materials to provide a comprehensive understanding of how these objects were crafted and used. A key argument is that Christian sarcophagi were not a completely new artistic form but evolved from earlier Roman traditions. They were produced using techniques similar to those of their pagan counterparts, with artisans carving reliefs into marble chests, often on commission. However, Christian sarcophagi introduced new imagery, incorporating biblical scenes, martyrs and theological themes that conveyed the Christian hope for resurrection. The chapter challenges the assumption that sarcophagus production declined abruptly, instead demonstrating that Christian sarcophagi remained in use well into the fifth and sixth centuries, particularly in centres such as Rome, Gaul and Constantinople. Ultimately, the chapter argues that early Christian funerary art was both a continuation of tradition and a medium for transformation. Sarcophagi, in particular, were not merely burial containers but also status symbols for the Christian elite, reflecting their social aspirations and religious identity.
The investigation of structural variants that may govern complex traits has significant importance. This is particularly true for the crossbred dairy cattle of Pakistan, which are deemed ideal for achieving optimal milk production and enhanced environmental adaptability in tropical conditions. This research detected and described copy number variation regions (CNVR) within the crossbred cattle genome. A GGP_HDv3_C chip containing 139,376 SNPs was utilized to genotype a cohort of 81 animals. In this study, 1055 CNVs were obtained after quality control, distributed across animals and encompassing all autosomes. From these, 268 CNVRs were detected, which covered 31.03 megabases, representing approximately 1.24% of the bovine genome. Functional analysis of these regions yielded 97 genes primarily associated with the immune and defense systems. Additionally, other observed categories encompassed production, health and reproduction. These findings enhanced the CNV map of bovines, offering the variant identification linked to traits subject to selection in both crossbred and indicine breeds of cattle.
Linear and integrable non-linear fractional evolution equations are discussed. Earlier results for the integrable fractional Korteweg–deVries (KdV) equation and the KdV hierarchy are reviewed. Using these as a guide, the fractional integrable Burgers equation and hierarchy and its solutions are analysed. Some explicit solutions are provided.
This chapter brings together the idea of bridges between economic and social concerns. The discussion reinforces the need to recognise the outer sphere of contracting in holding these connections together, recognising the role of contract law in protecting both economic values (including freedom and sanctity of contract) and social values (including relational autonomy and human dignity). A suggested path to succeed in these endeavours is to embrace the idea of complementarity in contract law, which enables us to accept the coexistence of ideas that may appear, initially, to be mutually exclusive. The idea of complementarity in contract law enables us to see economic and social values not as antagonistic, but as coexisting parts of interconnected spheres.
Chapter 10 returns to broader issues of the cultural politics of metaphor, examining the tensions between ethics and aesthetics in illness experience and healing. While the focus on language allows us to mobilize the richness of literature to explore illness experience, in doing so we may inadvertently downplay the material circumstances that determine health disparities and inequities. Against this apparent opposition, I argue that attention to the aesthetics of language and the creative functions of imagination and poeisis can help us understand the mechanisms of suffering and affliction and devise forms of healing that better respond to the needs of individuals within and across diverse cultures and contexts. Every choice of metaphor draws from and points toward a form of life. The critique of metaphors that begins with an appreciation of the qualities they confer on experience, and then moves out into the social world to identify ways that systems and structures are configured, rationalized, and maintained. A critical poetics of illness and healing can contribute to efforts to improve our institutions and achieve greater equity not only by recognizing and respecting difference and diversity but also by engaging with the particulars of each person’s experience.
This chapter considers how resort to the use of force is addressed in the UN Charter, with particular reference to self-defence, including collective self-defence, and anticipatory self-defence. The contemporary right of self-defence is also assessed in light of the rise and influence of non-State actors. United Nations-sanctioned use of force is considered, with particular reference to the mechanisms that exist in Chapter VII of the UN Charter. The use of force by invitation, humanitarian intervention and the 'responsibility to protect' are also considered.