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The anthropology and soteriology of western Christianity were radically reinterpreted in the fifth century CE by Augustine of Hippo, who constructed a fictional ‘Pelagianism’ to delegitimise opposition to his new theology of original sin, an absolutist account of prevenient grace, and predestination interpreted as preordainment. This chapter gives an outline of the issues involved in this attempt to relocate orthodoxy, the course of events relating to Pelagius and his defence of eastern ascetic Christianity, and the afterlife of controversy over this new account of the anthropology and soteriology of Christianity.
This chapter explores the economy of the later Roman Empire, with special emphasis on resource management, economic structures and regional variations. It highlights how land, labour and capital functioned within a largely agrarian system, with agriculture serving as the primary economic driver and tax base. The chapter examines diverse sources, including archaeological surveys, historical texts, coinage and environmental data. It analyses the effects of political instability, regional differentiation and resource distribution on economic trends. Case studies from North Gaul, Iberia, Italy and the Eastern Mediterranean reveal that economic activity was influenced by both local conditions and imperial policies. The study also incorporates ecological data, such as pollen analysis and lead pollution levels, to assess economic fluctuations. A central argument is that the later Roman economy was not a uniform system but a collection of interconnected regional economies. While political fragmentation led to economic contractions in some areas, others adapted through local specialisation and changing trade networks. This study thus challenges the view of economic collapse, instead emphasising resilience and adaptation, and calling for an interdisciplinary approach to better understand the complexities of late Roman economic life and its long-term transformations.
The iconoclast refusal to accept the use of images, particularly of Christ, in public and private worship in Byzantium, is often condemned as a heretical movement. But its emphasis on symbolic representations (the Cross and the Eucharist) and on spiritual veneration was essentially a reform of potentially idolatrous church practice.
The tattoos of the Pazyryk ice mummies are of paramount importance for the archaeology of Iron Age Siberia and are often discussed from a broad stylistic and symbolic perspective. However, deeper investigations into this cultural practice were hindered by the inaccessibility of quality data. Here, the authors use high-resolution, near-infrared data in conjunction with experimental evidence to re-examine the tools and techniques employed in Early Iron Age tattooing. The high-quality data allow for the previously unfeasible distinction of artist hands and enable us to put the individual back into the picture of a widespread but rarely preserved prehistoric practice.
This editorial explores dual harm – the co-occurrence of self-harm and aggression – particularly among forensic populations. Historically approached as two separate and even opposing behaviours, emerging evidence shows that those who engage in self-harm and aggression experience greater adversity and poorer outcomes. This underscores the importance of enhancing our understanding of dual harm. We review key developments within the field, including how dual harm may be best conceptualised and managed, and identify critical gaps in the literature. In order to improve the care and outcomes of those who engage in self-harm and aggression, emphasis is placed on adopting more integrated approaches that consider the duality of these behaviours, as well as the complex needs of this high-risk group, within research and practice.
This chapter examines the urban evolution of cities in the Eastern Mediterranean during Late Antiquity, focusing on their transformation from classical urban centres to more utilitarian and fortified settlements. It argues that rather than experiencing outright decline, cities in the East adapted to changing political, economic and religious realities. Archaeological evidence demonstrates a marked shift from monumental civic spaces to structures that emphasised military defence, religious identity and practical urban needs. The author discusses key aspects of urban change, including the gradual abandonment of traditional agoras, the decline of monumental temples and the repurposing of public buildings for Christian churches and administrative centres. The chapter also explores the impact of imperial policies on urban planning in reshaping cityscapes through large-scale church construction, fortification efforts and infrastructure projects. The increased militarisation of cities, with the establishment of fortified kastra and urban defences, is another major theme. Regional variations are examined, showing that while some cities, such as Constantinople and Thessaloniki, thrived under imperial patronage, others faced economic stagnation and contraction. The chapter concludes that while Late Antiquity brought profound transformations to urban life, cities in the East remained resilient, adapting to new social and political realities rather than simply collapsing.
The concept of total suffering is widely recognized in palliative care (PC), encompassing a range of interconnected and complex factors that collectively shape the evolving and individualized experience of a patient’s illness journey. Studies on will to live (WtL) in terminally ill patients have demonstrated its variability over time and various factors that influence these changes.
Methods
To objectively investigate the concept of total suffering and WtL; including their fluctuation over time and associations with sociodemographic, clinical, physical, and psychological symptoms in a sample of individuals with life-limiting conditions receiving PC. This multicenter Iberian study involved 3 centers in Portugal and 1 in Spain. A total of 107 individuals with life-limiting conditions consented to participate. To capture the dynamic and multifaceted components of total suffering, we had each participant completed the Edmonton Symptom Assessment Scale (ESAS) along an additional WtL visual analogue once daily over a 30-day period.
Results
WtL demonstrated various patterns over time. While some patterns reflected relative stability, other demonstrated substantive fluctuation during the course of illness. Significant correlations were observed between WtL and all other ESAS items. Moderate positive correlations were found between WtL and total ESAS score and its physical and psychological sub-scores. Spearman’s correlation coefficients between all physical and psychosocial items on the ESAS were statistically significant across all 45 correlations performed, with only 5 showing moderate strength; the remaining correlations were weaker.
Significance of results
Evidence-based understanding of WtL is critical to improving care for patients who experience suffering toward end-of-life and their families. Further research is needed to inform and refine interventions targeting total suffering.
Chapter 6 shifts its attention to the southern extremities of the lake and illustrates historical connections tying the lake together from another thematical angle: commercial flows. It examines the broader regional trade networks around Lake Kivu, emphasizing the interconnectedness of Goma and Bukavu in Congo with Gisenyi and Cyangugu in Rwanda. It introduces the concept of a “transboundary space,” shaped not only by colonial border impositions but also by preexisting social, political, and ecological asymmetries. The asymmetries created an “arbitrage economy,” enabling Africans, particularly those close to the border, to exploit differences across regions.
The chapter further considers cattle trade between the center of Rwanda and the westerns shores of Lake Kivu. This cattle trade connected different cultural and ecological zones, fostering commercial interactions long before colonial intervention. The chapter argues that the border accentuated existing disparities, emphasizing differences in the distribution and societal meanings of cattle. Despite colonial attempts to regulate the cattle trade, African traders managed to capitalize on their “liminality” – the ability to inhabit different spheres simultaneously. The chapter further underscores the significance of this “liminality” as it facilitated the negotiation of oppressive colonial structures. At times this “liminality” was embedded in formalized bonds of friendship, sometimes formalized through bloodpacts. Highlighting the everyday impact of borders demonstrates how they could be used to circumvent colonial policies, even though they could never undo the consequences of colonialism.
Iron deficiency has been associated with heart failure severity and mortality in children and adults. Intravenous iron therapy has been associated with improved outcomes for adults with heart failure. However, little is known about its impact and safety in children. We performed a single-centre review of all intravenous iron sucrose infusions prescribed to hospitalised patients ≤ 21 years of age with a primary cardiac diagnosis from 2020 to 2022. Ninety-one children (median age 6 years, weight 18 kg) received 339 iron sucrose infusions with a median dose of 6.5 mg/kg [5.1 mg/kg, 7.0 mg/kg]. At initial infusion, the majority (n = 63, 69%) had CHD, 70 patients (77%) were being managed by the advanced cardiac therapy team for heart failure, 13 (14%) were listed for heart transplant, 32 (35%) were on at least one vasoactive infusion, and 5 (6%) were supported with a ventricular assist device. Twenty infusions (6%) were associated with 27 possible infusion-related adverse events in 15 patients. There were no episodes of anaphylaxis or life-threatening adverse events. The most common adverse events were hypotension (n = 12), fever (n = 5), tachycardia (n = 3), and nausea/vomiting (n = 3). Eight of 20 infusion-related adverse events required intervention, and two infusions were associated with escalation in a patient’s level of care. Following intravenous iron repletion, patients’ serum iron, serum ferritin, transferrin saturation, and haemoglobin increased (p < 0.05 for all). In children hospitalised with cardiac disease, intravenous iron sucrose repletion is safe and may improve haemoglobin and iron parameters, including transferrin saturation and ferritin levels.
Chapter 18 offers a critical analysis of the types of remedies sought in climate cases and examines their implications within the legal landscape. Drawing on a comprehensive analysis of climate lawsuits from around the world, the authors provide insights into the diverse range of remedies that have been sought to address the adverse impacts of climate change. They then shed light on the different considerations and approaches that courts have taken when determining appropriate remedies. In their exploration of emerging best practices, the authors highlight instances where courts have adopted innovative and transformative approaches to remedies in climate litigation. They examine creative legal mechanisms that go beyond traditional compensatory measures and explore the potential of remedies such as injunctive relief, restitution, and declaratory judgments to address the multifaceted challenges posed by climate change.
This introduction grounds the middle-income (MI) trap by looking at the empirical realities of firms, sectors, national, and subnational institutions embedded in global value chains (GVCs). While MI-trap scholarship has shed light on macro-structural constraints, it often overlooks international production structures and micro-level agency. GVC research, in turn, captures firm strategies and governance structures but tends to underplay the role of domestic institutions and political coalitions. This Special Issue brings these two traditions into dialogue in order to examine how upgrading is (partially) attained—or how it fails—in MI countries.
The articles in the Issue focus on six countries—Argentina, Brazil, Chile, China, Malaysia, and Mexico—to analyze how public and private actors pursue upgrading strategies under MI-trap conditions. We develop a typology of Actors’ Upgrading Strategies along two dimensions: loci of agency (state vs. firm/chain) and modes of action (transformative vs. adaptive). This yields four conceptual categories: Transformative Policy Entrepreneurs, Adaptive Policy Implementers, Transformative Firm Upgraders, and Incremental Firm Repositioners. Collectively, the contributions offer a more textured and politically attuned understanding of upgrading under the MI trap in a world of GVCs, and bring us closer to understanding what it means to be caught in—or to find pathways out of—the trap.
This chapter examines the urban evolution of Trier in Late Antiquity, focusing on its transformation from a Roman provincial centre to an imperial capital. It discusses the city’s development from its foundation as Augusta Treverorum in the first century BCE to its peak as a key administrative and military hub in the late third and fourth centuries. This contribution integrates archaeological evidence, historical texts and urban-planning analysis, highlighting how Trier’s strategic location along the Moselle River contributed to its economic and political rise. The chapter also considers major infrastructure projects, including the construction of city walls, bridges, baths, an amphitheatre and a palace complex, demonstrating how imperial patronage shaped the city’s expansion. A significant theme is Trier’s role as an imperial residence under Constantine and his successors, with the city becoming a centre for coin production, governance and military strategy. The Christianisation of Trier is another focus, detailing the construction of basilicas, episcopal complexes and martyr shrines, which established it as an important religious centre. Despite political upheavals and invasions, Trier remained influential into the early medieval period, with the chapter concluding that its evolution reflects broader patterns of imperial consolidation, economic resilience and religious transformation in Late Antiquity.
Delving into fraternal succession, intermarriage practices, and levirate marriages of the Northern Qi dynasty (550–577), this article demonstrates that these practices served as pillars of stability for the imperial family. In this exploration, Empress Dowager Lou 婁太后 (501–562) emerges as the central figure behind these practices, playing a pivotal role in their implementation and wielding immense power as kingmaker. Starting from before the official reign of the Northern Qi, she personally chose her husband, laid the groundwork for him to become regent of the preceding Eastern Wei (534–550) court, and controlled the succession system to seat her own sons as emperors of the Northern Qi. Drawing on her Xianbei 鮮卑 roots, Empress Dowager Lou enforced an agenda of Inner Asian practices and politics in her pursuit to consolidate the rule and identity of the Northern Qi imperial family.