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The seroprevalence of Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-COV-2) IgG antibody was evaluated among employees of a Veterans Affairs Healthcare System to assess potential risk factors for transmission and infection.
All employees were invited to participate in a questionnaire and serological survey to detect antibodies to SARS-CoV-2 M protein as part of a facility-wide quality improvement and infection prevention initiative regardless of clinical or non-clinical duties. The initiative was conducted from June 8 to July 8, 2020.
Of the 2900 employees, 50.9% participated in the study, revealing a positive SARS-COV-2 seroprevalence of 4.9% (72/1476), [95% CI of 4.04% - 5.89%]. There were no statistically significant differences in the presence of antibody based on gender, age, frontline worker status, job title, performance of aerosol generating procedures or exposure to known patients with coronavirus infectious disease 2019 (COVID-19) within the hospital. Employees who reported exposure to a known COVID-19 case outside of work had a significantly higher seroprevalence at 14.84% (23/155) compared to those that did not 3.70% (48/1296), OR 4.53 [95% CI 2.67-7.68] p<0.0001. Notably, 29% of seropositive employees reported no history of symptoms for SARS-CoV-2 infection.
Seroprevalence of SARS-COV-2 among employees was not significantly different among those who provided direct patient care and those who did not, suggesting facility-wide infection control measures based were effective. Employees who reported direct personal contact with COVID-19 positive persons outside of work were more likely to have SARS-CoV-2 antibodies. Employee exposure to SARS-CoV-2 outside of work may introduce infection into hospitals.
This report describes the main adaptive and transformative changes adopted by the brand-new National Emergency Medical Service (NEMS) to face the novel coronavirus disease 2019 (COVID-19) in Sierra Leone, including ambulance re-distribution, improvements in communication flow, implementation of ad-hoc procedures and trainings, and budget re-allocation. In a time-span of four months, 1,170 COVID-19 cases have been handled by the NEMS through a parallel referral system, while efforts have been made to manage the routine emergencies of the country, causing a substantial intensification of daily activities.
Since the beginning of the coronavirus infectious disease 2019 (COVID-19) pandemic, an exponentially large amount of data has been published to describe the pathology, clinical presentations, and outcomes in patients infected with the severe acute respiratory syndrome coronavirus novel virus 2 (SARS-Cov-2). Although COVID-19 has been shown to cause a systemic inflammation predisposing the involvement of multiple organs, its mechanism affecting the urogenital system has not been well-documented. This care report presents the clinical course of two male patients with COVID-19 who developed sexual dysfunction, as anorgasmia, following recovery from the infection. Although no evidence of viral replication or inflammatory involvement could be identified in these cases’ urogenital organs, a lack of other known risk factors for anorgasmia points to the role of COVID-19 as the contributing factor.