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52383 results in Statistics and Probability

Page 310 of 2620

  • Transmission of viral pathogens in a social network of university students: the eX-FLU study

  • P.N. Zivich, M.C. Eisenberg, A.S. Monto, A. Uzicanin, R. S. Baric, T. P. Sheahan, J. J. Rainey, H. Gao, A. E. Aiello
  • Journal:
    Epidemiology & Infection / Volume 148 / 2020
    Published online by Cambridge University Press:
    14 August 2020, e267
    • Article
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  • Previous research on respiratory infection transmission among university students has primarily focused on influenza. In this study, we explore potential transmission events for multiple respiratory pathogens in a social contact network of university students. University students residing in on-campus housing (n = 590) were followed for the development of influenza-like illness for 10-weeks during the 2012–13 influenza season. A contact network was built using weekly self-reported contacts, class schedules, and housing information. We considered a transmission event to have occurred if students were positive for the same pathogen and had a network connection within a 14-day period. Transmitters were individuals who had onset date prior to their infected social contact. Throat and nasal samples were analysed for multiple viruses by RT-PCR. Five viruses were involved in 18 transmission events (influenza A, parainfluenza virus 3, rhinovirus, coronavirus NL63, respiratory syncytial virus). Transmitters had higher numbers of co-infections (67%). Identified transmission events had contacts reported in small classes (33%), dormitory common areas (22%) and dormitory rooms (17%). These results suggest that targeting person-to-person interactions, through measures such as isolation and quarantine, could reduce transmission of respiratory infections on campus.

Page 310 of 2620