This study examines how African Americans perceive and manage race and region as they migrate to the U.S. South—a region with a tenuous image of racial prejudice. The analysis is juxtaposed to literature that provides an inconsistent view of regional differences in prejudice. Some researchers argue that regional differences in levels of prejudice are now small, while other researchers argue that the South continues to be a place of much greater racial hostility. Guided by a spatial boundaries approach and using 127 narrative interviews with Black interregional migrants to Charlotte, North Carolina, results indicate that Black migrants focus less on levels of racial prejudice across regions and focus more on six dimensions of everyday racism they consider during migration. These dimensions include—the overtness/subtlety of prejudice, verbal and physical harassment, group economic opportunity, physical distance, racial symbols, and paternalism. Among these migrants, there is no consensus that the South is more or less racially hostile than other regions. They perceive most saliently that they are trading more subtle prejudice, higher levels of racial residential segregation, and greater constraints on Black economic opportunity in the North, for more overt prejudice, greater paternalism, and exposure to Confederate symbols in the South. Patterns also emerged in perceptions of regional boundaries based on class, motivation for moving, gender, and generation. Implications for theories of race and regionalism are discussed.