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Judith Shklar’s negative brand of liberalism is sometimes thought to have little to say about the ethical character required of citizens in liberal democracies, beyond the injunction to avoid cruelty. In this article, however, we argue that Shklar’s negative liberalism prescribes four distinctively political virtues—rational empathy, a healthy apprehension of state power, self-restraining tolerance, and being a good loser—that, taken together, constitute an ethos of skeptical vigilance. We survey Shklar’s criticisms of republican and communitarian accounts of civic virtue to clarify her concerns about attempts by the liberal state to cultivate these virtues and analyze the case of passive injustice to highlight tensions between active citizenship and liberal values. We conclude with some reflections on how Shklar’s political theory attempts to persuade her readers of the importance of adopting and practicing an ethos of skeptical vigilance.
Bemisia tabaci is one of the most important agricultural pests worldwide, and the combined application of multiple natural enemies such as predators and parasitoids can potentially control B. tabaci. The study examined whether the predator Orius similis and the parasitoid Encarsia formosa can synergistically control B. tabaci (crop: kidney bean). The greenhouse cage method was used to release O. similis and E. formosa alone or in combination in different ratios. The combined release of O. similis and E. formosa synergistically decreased the B. tabaci population when compared with O. similis or E. formosa alone. Additionally, O. similis + E. formosa decreased the number of E. formosa black pupae and adults in each crop stage. However, the niche overlap index of E. formosa with B. tabaci nymphs in the O. similis + E. formosa group was higher than in the E. formosa group. Grey correlation analysis revealed that the correlation degree between natural enemies and B. tabaci was the highest when the O. similis and E. formosa release ratio was 1:3. These findings indicate that the combined release of O. similis and E. formosa synergistically controlled B. tabaci with the release ratio 1:3 being optimal for field application.
In this work, we study the reaction-controlled dual bubbles ripening on a heterogeneous substrate with high surface wettability hysteresis, where the bubbles evolve with constant contact radius but varied contact angle. We first theoretically derived the governing kinetic equation of bubble curvature radius $R_B$, based on which we surprisingly found three possible ripening processes under six different conditions, i.e. the classical Ostwald ripening (the bubble with the larger curvature radius $R_B$ exhibits an increase in $R_B$, while the bubble with the smaller curvature radius $R_B$ experiences a decrease in $R_B$), the reversed ripening (converse to Ostwald ripening), and the consistent ripening ($R_B$ of both bubbles increases or reduces consistently). Further analyses from the aspects of chemical potential and free energy lead to an interesting finding that the $R_B$ of two bubbles finally reach egalitarianism, independently of different ripening processes. Numerical results obtained from two-phase lattice Boltzmann modelling demonstrate excellent agreement with theoretical predictions, specifically concerning the kinetic equation, the various ripening processes, and the egalitarianism of bubble radii $R_B$ after ripening completion.
This article examines media discourse about commuting travel time in Australia’s two largest metropolitan areas – Sydney and Melbourne – between 1970 and 2000. In major newspapers from each of the cities, reportage and commentary conveyed expanding commuting geographies oriented towards the mass pursuit of home ownership enabled by public policy and reflective of pluralism around households’ time use preferences. In a period when time use was widely understood as increasingly pressured, the choices available to households were frequently portrayed as responding to a wide range of opportunities but co-existed with discourses of market-driven compromise and consequences.
Despite the multiple advantages of 25-hydroxyvitamin D (calcifediol or 25(OH)D) compared to cholecalciferol, it is used sparingly. This study was planned to assess the safety and efficacy of supplementing daily 25 µg of calcifediol capsules vis-a-vis 100 µg (4000 IU) of cholecalciferol sachets in apparently healthy individuals with vitamin D deficiency in Chandigarh, India (latitude 30.7° North, 76.8° East). It was a prospective, interventional study to evaluate the effects of calcifediol vis-a-vis cholecalciferol. Following initial screening of 70 subjects in each group, 62 were included in the calcifediol and 41 in the cholecalciferol group. Forty-six from calcifediol and 37 from cholecalciferol group completed the 6-month follow up. There was a significant increase in serum 25(OH)D (355% in cholecalciferol & 574% in calcifediol groups, respectively, p < 0.001) and 1,25 (OH)2D (p < 0.001) with a marked decrease in iPTH (p < 0.001) and ALP (p = 0.016) in both groups. Though serum ALP decreased significantly more in the calcifediol group than the cholecalciferol group, no appreciable difference in other biochemical parameters was noted between the groups. No episodes of hypercalcaemia or incidence of new renal stone disease were observed during follow-up. However, hypercalciuria (spot urine calcium creatinine > 0.2 mg/mg) was noted in 8/46 individuals in the calcifediol group and 5/37 individuals in the cholecalciferol group at final visit with no significant difference between two groups. This study establishes the efficacy and safety of correcting vitamin D deficiency with daily 25 µg calcifediol capsules as an alternative to 4000 IU (100 µg) cholecalciferol sachets.
Low self-esteem is an important and potentially modifiable risk factor for the development and outcome of psychotic disorders. The factors involved in low self-esteem in psychotic disorders are not yet fully understood. The current study aims to investigate the cross-sectional and longitudinal associations between (changes in) self-esteem and severity of psychotic symptoms, internalized stigma, negative reaction to antipsychotics, personal recovery, childhood bullying, childhood trauma, and social support in symptomatically remitted first-episode psychosis (FEP) patients.
Methods
Data from the ongoing longitudinal Handling Antipsychotic Medication: Long-term Evaluation of Targeted Treatment study were used. Participants were in symptomatic remission for 3–6 months after the FEP. Cross-sectional associations (N = 299) were investigated through Pearson’s correlations, and longitudinal changes (N = 238) were investigated via linear regressions with inverse probability weighting.
Results
Cross-sectionally, we found that lower self-esteem was related to higher severity of symptoms, higher internalized stigma, higher childhood trauma (specifically emotional neglect), higher childhood bullying, more negative side effects of antipsychotic medication, lower personal recovery, and lower social support. Longitudinally, contrary to our hypothesis, we found that higher baseline internalized stigma, higher childhood trauma (specifically emotional abuse), and a higher baseline negative subjective reaction to antipsychotics predicted an increase in self-esteem after 6 months. Furthermore, a decrease in psychotic symptoms, internalized stigma, and negative subjective reaction to antipsychotics, and an increase in social support predicted an increase in self-esteem.
Conclusions
Early intervention programs for psychotic disorders should target factors related to changes in self-esteem. This might improve self-esteem and thereby promote recovery.
Balancing pest control and pollination is a dual challenge for pollinator-dependent crops and the producers that grow them. For organic cucurbit production, organic compliant insecticides underperform at suppressing pests and can have nontarget impacts on pollinators. One promising alternative is pest-protective row covers, which successfully exclude insect pests from damaging cucurbit crops. However, they also exclude pollinators. In this study across two years, four row cover pollination management strategies were compared for their efficacy for acorn squash (Cucurbita pepo L.). Row covers were installed at crop transplant and four treatments were initiated: on–off (row cover removed at flowering), on–off–on (row cover removed at flowering and reinstalled post-flowering), open ends (row cover tunnel ends opened at flowering and reclosed post-flowering), and full season (row cover installed through whole season, commercial bumble bee colonies installed at flowering). During the pre-flowering net stage (when row covers were installed), all treatments had low pest abundance and were not statistically different. In the post-flowering net stage, the full season and open ends treatments had statistically lower cucumber beetle pest abundance relative to the on–off–on treatment. The number of seeds per squash fruit weight, an indicator of pollination success, was statistically lower in the full season treatment relative to the on–off–on treatment in 2021, which may be explained by the statistically lower bee activity in the full season treatment relative to the on–off and on–off–on treatments. Squash seeds were not counted in 2020. The open ends treatment had statistically higher marketable yield than the full season and on–off–on treatments in 2020; in 2021, there was no difference in marketable yield across treatments. For the open ends treatment, increased distance from the opened tunnel ends significantly decreased the pest abundance, while it significantly increased marketable yield. However, there was no relationship between pollinator activity and distance to the tunnel opening. This two-year study suggests the open ends strategy had the most consistently high yields, while it reduced pollination management effort and eliminated the costs of commercial bee colonies compared to other treatments. Only minor pressure from insect-vectored diseases was observed during the study, thus, the advantages of each pollination strategy should be considered in relation to varying pest, pollinator, and disease conditions.
Does group-based tribal thinking against ethnic out-groups condition support for both liberal and illiberal policies? Our thesis is that, irrespective of the direction of the policy (progressive or conservative), nativists express selective support for policies based on different signals of group-identity: descriptive markers, group-based substantive representation, in- and out-group norms, and group-based reasoning. We test this theoretical expectation using a novel AI-powered visual conjoint experiment in the Netherlands and Germany that asked individuals to select between hypothetical educational reform proposals presented by civic actors during a public consultation. Empirically, our results demonstrate that citizens, on average, are indeed selectively (il)liberal and that this instrumental policy support is greater among those with higher levels of underlying nativism. Specifically, we show that—among our multidimensional markers of group-based identities, norms, and reasoning—group-based substantive representation and in-group norms are the strongest determinants of support for diverse reform proposals. These findings have key implications on the malleable nature of citizens’ support for the backsliding of the liberal tenets of democracy as well as the persuasive power of out-group disidentification.
South Africa’s democracy is 30 years old, and for 30 years the courts have been interpreting the right of access to adequate housing found in section 26 of the Constitution. Many parts of this right have been developed; one such development is that courts have found that the right includes a duty on the state to provide (temporary) emergency alternative accommodation in eviction matters to those facing homelessness. Throughout the years, courts have grappled with the suitability of this alternative accommodation; it finally seems like some clarity has been reached regarding when alternative accommodation would be considered suitable, due to the courts’ recent acceptance of alternative accommodation offered by the state as suitable. This article considers how the courts currently determine the suitability of emergency accommodation and what types of alternative accommodation has been accepted; it further explores the issues arising from these findings.
This article is about how Calcutta’s image as the world’s foremost crisis city was constructed from the mid-1950s, and how it came to be used by a broad political spectrum—from the American left and right to, allegedly, Fidel Castro—for rationalizing a variety of positions on urban development. This hyperreal Calcutta was the product of a global conjuncture which centred on Western, mainly American, anxieties about how large cities of the Global South could destabilize the postwar world order and development paradigms. It influenced global urban development by challenging the anti-urban bias of development institutions of the 1950s and bolstering the case for state-led interventions thereafter. However, from the mid-1970s, Calcutta’s ‘refusal to die’ became an example used by the American right to argue in favour of planned shrinkage and benign neglect of cities. Calcutta’s resonance in global debates on urban issues lay in the city’s confrontation with ‘life’ and ‘death’ which helped mask divisive issues such as race and immigration in discussions about American and Western cities.
Ocmulgee Mounds National Historical Park, located in Macon, Georgia, is one of the most iconic cultural sites in the Southeast and is a Traditional Cultural Place (TCP) of the Muscogee Nation and other federally recognized Tribal Nations. Early work (1933–1941) revealed a network of earthen monuments and other features. Prior to our work, there were only two radiocarbon dates from the primary Native American occupation of Ocmulgee. Both were run in the 1960s—and only one is from the famous Earthlodge community building. These assays contributed to a general chronological assignment of the site to AD 1015. Our new dating program—including wiggle-matched radiocarbon dates from one of the timbers of this building—indicates a later construction for the Earthlodge and likely continuous occupation for other areas of the site, calling into question beliefs about Ocmulgee and its place in interpretative constructs. This work is a collaborative effort that includes Muscogee Nation, academics, National Park Service archaeologists, and private citizens. The results have implications for understanding not only the Muskogean-speaking people’s histories and their relationship to TCPs but also how we can begin to conduct archaeology in a way that strengthens descendants’ connections to ancestral homelands.
on an asymptotically hyperbolic manifold $(X, g^{+})$ with conformal infinity $(M,[\hat{h}])$, where $s\in (0,1)$, $P_{\hat{h}}^s$ is the fractional conformally invariant operators, $1 \lt p \lt \frac{n+2s}{n-2s}$. By Lyapunov–Schmidt reduction method, we prove the existence of solutions whose peaks collapse, as $\varepsilon$ goes to zero, to a $C^1$-stable critical point of the mean curvature $H$ for $0 \lt s \lt {1}/{2}$ or a $C^1$-stable critical point of a function involving the scalar curvature and the second fundamental form for ${1}/{2}\le s \lt 1$.
Haemonchus contortus, a highly pathogenic gastrointestinal nematode, significantly impacts small ruminant production, causing substantial economic losses in sheep and goat farming. This study examined the genetic diversity and population structure of 171 H. contortus isolates collected from the abomasa of sheep slaughtered across 8 distinct regions in Xinjiang, China. Using sequence analysis, phylogenetic reconstruction and population genetic analyses of the mitochondrial nad4 gene, we identified 163 haplotypes, with haplotype diversity ranging from 0.995 to 1.000 and nucleotide diversity from 0.02007 to 0.03145. The Tacheng population displayed the highest nucleotide diversity. Analysis of molecular variance revealed that 91.83% of genetic variation occurred within populations, with minimal differentiation among them (Fst: −0.01296 to 0.04274). Neutrality tests (Tajima’s D and Fu’s Fs) indicated no recent population bottlenecks. Phylogenetic and haplotype network analyses showed no distinct geographic clustering, suggesting extensive gene flow, likely facilitated by host movement. These findings provide critical insights into the genetic structure of H. contortus in Xinjiang, informing strategies for managing anthelmintic resistance and controlling this economically significant parasite.
To identify host and clinical risk factors contributing to the development of Clostridioides difficile infection (CDI) among colonized patients.
Design:
Retrospective, matched case-control study.
Setting:
Duke University Health System, including 3 hospitals and affiliated outpatient clinics.
Participants:
Adult patients who underwent ≥2 two-step C. difficile tests (nucleic acid amplification test (NAAT) followed by toxin enzyme immunoassay) between 03/15/2020–12/31/2023. Cases were patients with C. difficile colonization (NAAT+/toxin–) who converted to CDI (NAAT+/toxin+) within 90 days; controls were colonized patients who remained toxin-negative. Cases were matched to controls by date of index testing (±1 year).
Methods:
Data collection encompassed a 90-day “pre-exposure” period preceding index testing and a ≤ 90-day “exposure” period between index and repeat testing. Antibiotic use was stratified by risk for each period. Multivariate conditional logistic regression with forward selection was used to identify predictors of progression.
Results:
Among 2,212 colonized patients, 71 cases and 133 matched controls were identified. Several host and clinical characteristics were independently associated with progression to CDI in our multivariate model. Notably, high-risk antibiotic use across the pre-exposure and exposure periods was associated with greater odds of progression to CDI compared to other patterns of antibiotic use (adjusted odds ratio 2.70; P = .03).
Conclusions:
Sustained exposure to high-risk antibiotics was a strong predictor of the progression from C. difficile colonization to infection, underscoring the need for further research on longitudinal stewardship strategies for CDI prevention, particularly among patients previously identified as colonized.