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Although natural hazards (e.g., tropical cyclones, earthquakes) disproportionately affect developing countries, most research on their mental health impact has been conducted in high-income countries. We aimed to summarize prevalences of mental disorders in Global South populations (classified according to the United Nations Human Development Index) affected by natural hazards.
Methods
To identify eligible studies for this meta-analysis, we searched MEDLINE, PsycINFO and Web of Science up to February 13, 2024, for observational studies with a cross-sectional or longitudinal design that reported on at least 100 adult survivors of natural hazards in a Global South population and assessed mental disorders with a validated instrument at least 1 month after onset of the hazard. Main outcomes were the short- and long-term prevalence estimates of mental disorders. The project was registered on the International Prospective Register of Systematic Reviews (CRD42023396622).
Results
We included 77 reports of 75 cross-sectional studies (six included a non-exposed control group) comprising 82,400 individuals. We found high prevalence estimates for post-traumatic stress disorder (PTSD) in the general population (26.0% [95% CI 18.5–36.3]; I2 = 99.0%) and depression (21.7% [95% CI 10.5–39.6]; I2 = 99.2%) during the first year following the event, with similar prevalences observed thereafter (i.e., 26.0% and 23.4%, respectively). Results were similar for regions with vs. without recent armed conflict. In displaced samples, the estimated prevalence for PTSD was 46.5% (95% CI 39.0–54.2; k = 6; I2 = 93.3). We furthermore found higher symptom severity in exposed, versus unexposed, individuals. Data on other disorders were scarce, apart from short-term prevalence estimates of generalised anxiety disorder (15.9% [95% CI 4.7–42.0]; I2 = 99.4).
Conclusions
Global South populations exposed to natural hazards report a substantial burden of mental disease. These findings require further attention and action in terms of implementation of mental health policies and low-threshold interventions in the Global South in the aftermath of natural hazards. However, to accurately quantify the true extent of this public health challenge, we need more rigorous, well-designed epidemiological studies across diverse regions. This will enable informed decision making and resource allocation for those in need.
Sexual unwellness (SU) has been linked to a lack of sexual satisfaction and to an incapacity to maintain sexual relations.
Objectives
The objective of this cross-cultural study is to shed light on older adults’ perspectives on SU across cultures.
Methods
Eighty-three older participants (65 to 98 years of age) took part in this qualitative study. Participants lived in the community and were of two different nationalities (Portuguese and Mexican). Semi-structured interviews were conducted, and content analysis was then carried out.
Results
SU emerged in the findings of the content analysis through six themes: Dissatisfying Sexual Experiences; Feelings of Isolation; Spirituality; Medication; Unattractiveness and Pain. The most common theme among older Portuguese participants was ‘Dissatisfying Sexual Experiences’ (25.5%). ‘Feelings of Isolation’ was most common among older Mexican participants (13.7%).
Conclusions
A diversity of experiences of older adults in relation to SU was highlighted in this study. Moreover, cross-cultural research on the construct of SU is essential for understanding the cultural differences in the conceptualization of the construct and how these themes may influence the quality of sexual life in old age.
Background: Efgartigimod, a human immunoglobulin G (IgG)1 antibody Fc fragment, blocks the neonatal Fc receptor, decreasing IgG recycling and reducing pathogenic IgG autoantibody levels. ADHERE assessed the efficacy and safety of efgartigimod PH20 subcutaneous (SC; co-formulated with recombinant human hyaluronidase PH20) in chronic inflammatory demyelinating polyneuropathy (CIDP). Methods: ADHERE enrolled participants with CIDP (treatment naive or on standard treatments withdrawn during run-in period) and consisted of open-label Stage A (efgartigimod PH20 SC once weekly [QW]), and randomized (1:1) Stage B (efgartigimod or placebo QW). Primary outcomes were clinical improvement (assessed with aINCAT, I-RODS, or mean grip strength; Stage A) and time to first aINCAT score deterioration (relapse; Stage B). Secondary outcomes included treatment-emergent adverse events (TEAEs) incidence. Results: 322 participants entered Stage A. 214 (66.5%) were considered responders, randomized, and treated in Stage B. Efgartigimod significantly reduced the risk of relapse (HR: 0.394; 95% CI: 0.25–0.61) versus placebo (p=0.000039). Reduced risk of relapse occurred in participants receiving corticosteroids, intravenous or SC immunoglobulin, or no treatment before study entry. Most TEAEs were mild to moderate; 3 deaths occurred, none related to efgartigimod. Conclusions: Participants treated with efgartigimod PH20 SC maintained a clinical response and remained relapse-free longer than those treated with placebo.
Both impulsivity and compulsivity have been identified as risk factors for problematic use of the internet (PUI). Yet little is known about the relationship between impulsivity, compulsivity and individual PUI symptoms, limiting a more precise understanding of mechanisms underlying PUI.
Aims
The current study is the first to use network analysis to (a) examine the unique association among impulsivity, compulsivity and PUI symptoms, and (b) identify the most influential drivers in relation to the PUI symptom community.
Method
We estimated a Gaussian graphical model consisting of five facets of impulsivity, compulsivity and individual PUI symptoms among 370 Australian adults (51.1% female, mean age = 29.8, s.d. = 11.1). Network structure and bridge expected influence were examined to elucidate differential associations among impulsivity, compulsivity and PUI symptoms, as well as identify influential nodes bridging impulsivity, compulsivity and PUI symptoms.
Results
Results revealed that four facets of impulsivity (i.e. negative urgency, positive urgency, lack of premeditation and lack of perseverance) and compulsivity were related to different PUI symptoms. Further, compulsivity and negative urgency were the most influential nodes in relation to the PUI symptom community due to their highest bridge expected influence.
Conclusions
The current findings delineate distinct relationships across impulsivity, compulsivity and PUI, which offer insights into potential mechanistic pathways and targets for future interventions in this space. To realise this potential, future studies are needed to replicate the identified network structure in different populations and determine the directionality of the relationships among impulsivity, compulsivity and PUI symptoms.
To test the double-layer theory of swelling as applied to layer silicates, the interlayer separation, λ, in a Li-saturated vermiculite from Grouse Creek, Utah, was measured as a function of the swelling pressure, II. An oriented sample of the vermiculite (46-105 μm) was placed in an environmental chamber mounted on an X-ray diffractometer and compressed between N2 gas and a porous membrane in contact with a solution draining to the outside atmosphere. After equilibration at each of several successively higher gas pressures, the c-axis spacing was measured by X-ray diffraction, and the corresponding X was calculated by subtracting the thickness of an elementary silicate layer. The results of these measurements showed that. (1) the relation between II and λ for vermiculite is the same as that previously observed for Na-montmorillonite, i.e., II is an exponential function of 1/λ. (2) the values of II predicted by double-layer theory are much smaller than those observed if the surface potential is assigned the appropriate value; an. (3) the observed relation between II and λ does not have the form predicted by this theory. On the basis of these results, a repulsive force not ascribable to double-layer overlap must be primarily responsible for swelling; this force must result from the in-depth perturbation of the water by the surfaces of the vermiculite layers.
In recognition of an increasing number of high-consequence infectious disease events, a group of subject-matter experts identified core safety principles that can be applied across all donning and doffing protocols for personal protective equipment.
Growing evidence suggests that in addition to pathophysiological, there are psychological risk factors involved in the development of Long COVID. Illness-related anxiety and dysfunctional symptom expectations seem to contribute to symptom persistence.
Aims
With regard to the development of effective therapies, our primary aim is to investigate whether symptoms of Long COVID can be improved by a targeted modification of illness-related anxiety and dysfunctional symptom expectations. Second, we aim to identify additional psychosocial risk factors that contribute to the persistence of Long COVID, and compare them with risk factors for symptom persistence in other clinical conditions.
Method
We will conduct an observer-blinded, three-arm, randomised controlled trial. A total of 258 patients with Long COVID will be randomised into three groups of equal size: targeted expectation management in addition to treatment as usual (TAU), non-specific supportive treatment plus TAU, or TAU only. Both active intervention groups will comprise three individual online video consultation sessions and a booster session after 3 months. The primary outcome is baseline to post-interventional change in overall somatic symptom severity.
Conclusions
The study will shed light onto the action mechanisms of a targeted expectation management intervention for Long COVID, which, if proven effective, can be used stand-alone or in the context of broader therapeutic approaches. Further, the study will enable a better understanding of symptom persistence in Long COVID by identifying additional psychological risk factors.
Childhood family income is a powerful predictor of academic achievement and mental health. Here, we ask whether children living in poverty–those whose family incomes are not sufficient to meet their material needs–who beat the odds by succeeding academically are subsequently either protected from, or more at risk for, internalizing disorders. Prior research indicates that children in poverty with better academic performance and more depressive symptomatology tend to have higher temporal coupling between lateral frontoparietal network (LFPN; supports executive functions) and Default Mode Network (DMN; supports internally-directed thought) than lower-performing children in poverty, in direct contrast to the pattern observed for children above poverty. Thus, an open question is whether this pattern of connectivity adaptive for children in poverty has maladaptive long-term consequences, particularly for mental health.
Objectives
In this pre-registered study, we analyzed concurrent data from 8,091 children (1,307 in poverty) in the ABCD study at baseline (ages 9-10y). We performed linear mixed effects models to investigate whether both higher LFPN-DMN connectivity and grades are linked to more internalizing symptoms concurrently, and whether this differs for children above and below poverty.
Methods
We performed linear mixed effects models to investigate whether both higher LFPN-DMN connectivity and grades are linked to more internalizing symptoms concurrently, and whether this differs for children above and below poverty.
Results
We found that higher grades were associated with fewer internalizing symptoms for both children above and below poverty; this association was stronger for children below poverty. In addition, LFPN-DMN connectivity showed a significant negative correlation with internalizing symptoms at this age. However, when looking at internalizing symptoms separately - that is, anxiety/depression, withdrawal/depression, and somatic symptoms - we found that higher LFPN-DMN connectivity for children below poverty was associated with higher withdrawal/depression symptoms, but fewer somatic symptoms, pointing to a dissociation in what pattern of brain connectivity is most adaptive for the development of internalizing symptoms vs. physical health. These somatic symptoms highlight potential maladaptive consequences of resilience for children growing up in unequal structural conditions.
Conclusions
This research has important implications for supporting children in poverty by illuminating mechanisms for, and potential maladaptive consequences of, their resilience in academic contexts.
I ask in this chapter how embodied memories of violence and survival are captured through the various sensory reconstructions of war as a sensuous world of bodily transgressions. War affects a person’s sensibilities through the engendering of a shift in sense perception owing to unexpected turns of events. I consider how a repertoire of different genres of social texts about war and violence – from songs, letters, and poetry, to autobiographies, oral histories and others – form rich and sensuous repositories. These texts undergird how multiple facets and first-hand experiences of horror and disbelief are enacted through sensory modalities that either work individually or intersectionally. As much as the sensory provide vital clues for what might happen next – in one’s home, in the prison, or at a concentration centre – the sensory also strikes fear and anxiety on what the next course of action might be. By drawing upon ontological security theory, I show how these transpire within possible or potential recourse in differing contexts of precariousness. The senses therefore serve as a potent catalyst as they both incite fear and insecurity, but also latently security and some stability as they provide cues and information for social actors.
The senses provide important everyday and symbolic media through which social order is routinely looked at. Throughout these multifold processes and in relation to exchange and imitation, we are able to discern a number of important issues that arise in the agenda to compose a sensory anthropology of Asia. First, senses serve as vehicles of knowledge across the whole array of everyday social domains in terms of how they organise human–nonhuman experience. Second, comparative approaches initiated herein are not only a response to either Western- or Asian-centric sensory analysis. They further advance the scope of sensory scholarship by prompting inter- and intra-cultural dialogue on the subject. Third, sensory transnationalism illustrates how sensory orders and practices work, and where established sensory norms are responded to by social actors adhering to different sensory scripts in cross-cultural exchanges. The broader intention is to spotlight how sensory cultures, sentient practices and encounters transpire as a way of comprehending Asia through sense perception as a newer perspective in social and cultural anthropology. In doing so, I inquire further both into the breadth and depth of how to articulate the social lives and textures of the senses toward crafting the future of sensory anthropology.
In this chapter, I address cross-cultural encounters of two (or more) sets of sensory scripts. These encounters are evident in the wider literature on colonialism, migration and other local–foreign interfaces. In doing so, it serves as an important reminder for one to take heed of multiple axes of sensory similarities and differences, in addition to a merely the East–West core axis of difference. I also turn the lens around by showing how local populations on the reverse, discern colonial or foreign communities through their sensory faculties as a counterpoint. The focus lies in demonstrating how sensory interfaces arising from these processes and movements of people are theorised using the notion of sensory transnationalism. I map this notion onto colonial–local sensory encounters and propose four modes of sensory engagement: reception, rejection, regulation, and reproduction. These modes collectively show how sensory encounters, stemming from contrasting power positions, lend a different understanding of empire and its everyday lived constructions, including how colonial impositions of modernity through sensory regulatory schemes are also met with resistance. Consequently, categories of colonisers and colonised are unsettled instead of being deployed as inherently asymmetrical categories.
I establish conceptual connections between food, the senses, and political life by drawing upon examples of gastropolitical moments which comprise charged meanings that may be unveiled through a closer inspection of the sensible. They reveal different power dynamics of cohesion and tension between varying sets of political actors. The senses aid in exemplifying political relationships and connections, directing us to particular aspects of political form and practice. This chapter therefore serves as a critical instigation of combining analytical approaches from sociology, anthropology, diplomacy, and food and foodways in appraising the importance of culinary–political encounters both within and between nations. Through such interdisciplinary conversations, it adopts a sensory reading and discussion of gastropolitical exchanges. Subsequently, my analysis is geared towards developing a political life of sensation that builds a theoretical and empirical connection between the political and the sensible. Such a sensory perspective explores the sociopolitical metaphors of taste and other accompanying sense experience. These are addressed through my proposed notion of political gustemology which I utilise in this chapter to illustrate the deployment of sensory knowledge and power in both actual sensorial exchanges and metaphorical takes on the sensory.
I ask how sensory models are established and operate across different cultures, including their variant ethnographical nuances. This problematises the interplay of the senses whereby sensory conjunctions or amalgams form part of everyday life and ritual practices in many societies, as opposed to the broader compartmentalisation of the senses in Western aesthetics. The chapter compares a range of categories that delineate different senses, as well as the varying modalities per sense. This is accomplished through an investigation of linguistic descriptors of senses as a starting point. How a particular culture names the senses that wield cultural importance is however not merely an exercise in description or enumeration. I analyse sensory nomenclatures in a three-fold manner to unveil the phenomenological epistemology of the senses. First, I engage with the numbers of modalities per sense in order to acknowledge alternate sensory models beyond the hegemonic Romano–Grecian five-sense categorisation. Second, I query the social significance of the nuances of each sense. Third, I raise examples of how two or more senses may be employed synaesthetically. By focusing on cultural interpretations of sensory practices, pairings, and intersections, this approach sheds analytical attention upon everyday orderings of sensory categories and their cultural significance.