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The kinetic stability of collisionless, sloshing beam-ion ($45^\circ$ pitch angle) plasma is studied in a three-dimensional (3-D) simple magnetic mirror, mimicking the Wisconsin high-temperature superconductor axisymmetric mirror experiment. The collisional Fokker–Planck code CQL3D-m provides a slowing-down beam-ion distribution to initialize the kinetic-ion/fluid-electron code Hybrid-VPIC, which then simulates free plasma decay without external heating or fuelling. Over $1$–$10\;\mathrm{\unicode{x03BC} s}$, drift-cyclotron loss-cone (DCLC) modes grow and saturate in amplitude. The DCLC scatters ions to a marginally stable distribution with gas-dynamic rather than classical-mirror confinement. Sloshing ions can trap cool (low-energy) ions in an electrostatic potential well to stabilize DCLC, but DCLC itself does not scatter sloshing beam-ions into the said well. Instead, cool ions must come from external sources such as charge-exchange collisions with a low-density neutral population. Manually adding cool $\mathord {\sim } 1\;\mathrm{keV}$ ions improves beam-ion confinement several-fold in Hybrid-VPIC simulations, which qualitatively corroborates prior measurements from real mirror devices with sloshing ions.
It remains unclear which individuals with subthreshold depression benefit most from psychological intervention, and what long-term effects this has on symptom deterioration, response and remission.
Aims
To synthesise psychological intervention benefits in adults with subthreshold depression up to 2 years, and explore participant-level effect-modifiers.
Method
Randomised trials comparing psychological intervention with inactive control were identified via systematic search. Authors were contacted to obtain individual participant data (IPD), analysed using Bayesian one-stage meta-analysis. Treatment–covariate interactions were added to examine moderators. Hierarchical-additive models were used to explore treatment benefits conditional on baseline Patient Health Questionnaire 9 (PHQ-9) values.
Results
IPD of 10 671 individuals (50 studies) could be included. We found significant effects on depressive symptom severity up to 12 months (standardised mean-difference [s.m.d.] = −0.48 to −0.27). Effects could not be ascertained up to 24 months (s.m.d. = −0.18). Similar findings emerged for 50% symptom reduction (relative risk = 1.27–2.79), reliable improvement (relative risk = 1.38–3.17), deterioration (relative risk = 0.67–0.54) and close-to-symptom-free status (relative risk = 1.41–2.80). Among participant-level moderators, only initial depression and anxiety severity were highly credible (P > 0.99). Predicted treatment benefits decreased with lower symptom severity but remained minimally important even for very mild symptoms (s.m.d. = −0.33 for PHQ-9 = 5).
Conclusions
Psychological intervention reduces the symptom burden in individuals with subthreshold depression up to 1 year, and protects against symptom deterioration. Benefits up to 2 years are less certain. We find strong support for intervention in subthreshold depression, particularly with PHQ-9 scores ≥ 10. For very mild symptoms, scalable treatments could be an attractive option.
Despite the increased awareness and action towards Equality, Diversity and Inclusion (EDI), the glaciological community still experiences and perpetuates examples of exclusionary and discriminatory behavior. We here discuss the challenges and visions from a group predominantly composed of early-career researchers from the 2023 edition of the Karthaus Summer School on Ice Sheets and Glaciers in the Climate System. This paper presents the results of an EDI-focused workshop that the 36 students and 12 lecturers who attended the summer school actively participated in. We identify common threads from participant responses and distill them into collective visions for the future of the glaciological research community, built on actionable steps toward change. In this paper, we address the following questions that guided the workshop: What do we see as current EDI challenges in the glaciology research community and which improvements would we like to see in the next fifty years? Contributions have been sorted into three main challenges we want and need to face: making glaciology (1) more accessible, (2) more equitable and (3) more responsible.
Increasing daylight exposure might be a simple way to improve mental health. However, little is known about daylight-symptom associations in depressive disorders.
Methods
In a subset of the Australian Genetics of Depression Study (N = 13,480; 75% female), we explored associations between self-reported number of hours spent in daylight on a typical workday and free day and seven symptom dimensions: depressive (overall, somatic, psychological); hypo-manic-like; psychotic-like; insomnia; and daytime sleepiness. Polygenic scores for major depressive disorder (MDD); bipolar disorder (BD); and schizophrenia (SCZ) were calculated. Models were adjusted for age, sex, shift work status, employment status, season, and educational attainment. Exploratory analyses examined age-stratified associations (18–24 years; 25–34 years; 35–64 years; 65 and older). Bonferroni-corrected associations (p < 0.004) are discussed.
Results
Adults with depression reported spending a median of one hour in daylight on workdays and three hours on free days. More daylight exposure on workdays and free days was associated with lower depressive (overall, psychological, somatic) and insomnia symptoms (p’s<0.001), but higher hypo-manic-like symptoms (p’s<0.002). Genetic loading for MDD and SCZ were associated with less daylight exposure in unadjusted correlational analyses (effect sizes were not meaningful). Exploratory analyses revealed age-related heterogeneity. Among 18–24-year-olds, no symptom dimensions were associated with daylight. By contrast, for the older age groups, there was a pattern of more daylight exposure and lower insomnia symptoms (p < 0.003) (except for 25–34-year-olds on free days, p = 0.019); and lower depressive symptoms with more daylight on free days, and to some extent workdays (depending on the age-group).
Conclusions
Exploration of the causal status of daylight in depression is warranted.
Compared with other areas of mental health research that are focused on the active and early management of youth presenting in the early stages of major mental disorders, there has been a relative lack of focus on young people with emerging or established bipolar disorders. Recently, this has stimulated both international professional societies (e.g., International Society for Bipolar Disorders [ISBD] Early Intervention Task Force) and funding agencies from Canada, UK, Australia, and the USA – including the Daymark Foundation (Jain et al. 2023), Wellcome Trust (2022), National Health and Medical Research Council, and BD2 – to promote a focus on identifying the major challenges in this field and gathering support for novel research and clinical service programmes.
Maximum likelihood estimates of item parameters of a scholastic aptitude test were computed using the normal and logistic models. The goodness of fit of ogives specified by the pairs of item parameters to the observed data was determined for all items. While negligible differences in the limen values were found, differences in item discrimination indices indicated that interpretation of these indices requires separate frames of reference. The empirical results showed the logistic model to be a useful alternative to the normal model in item analysis.
Hierarchical Bayes procedures for the two-parameter logistic item response model were compared for estimating item and ability parameters. Simulated data sets were analyzed via two joint and two marginal Bayesian estimation procedures. The marginal Bayesian estimation procedures yielded consistently smaller root mean square differences than the joint Bayesian estimation procedures for item and ability estimates. As the sample size and test length increased, the four Bayes procedures yielded essentially the same result.
The problem of comparing two sociometric matrices, as originally discussed by Katz and Powell in the early 1950’s, is reconsidered and generalized using a different inference model. In particular, the proposed indices of conformity are justified by a regression argument similar to the one used by Somers in presenting his well-known measures of asymmetric ordinal association. A permutation distribution and an associated significance test are developed for the specific hypothesis of “no conformity” reinterpreted as a random matching of the rows and (simultaneously) the columns of one sociometric matrix to the rows and columns of a second. The approximate significance tests that are presented and illustrated with a simple numerical example are based on the first two moments of the permutation distribution, or alternatively, on a random sample from the complete distribution.
The sampling properties of four item discrimination indices (biserial r, Cook’s index B, the U–L 27 per cent index, and Delta P) were investigated in order to ascertain their sampling properties when small samples drawn from actual test data rather than constructed data were employed. The empirical results indicated that the mean index values approximated the population values and that values of the standard deviations computed from large sample formulas were good approximations to the standard deviations of the observed distributions based on samples of size 120 or less. Goodness of fit tests comparing the observed distributions with the corresponding distribution of the product-moment correlation coefficient based upon a bivariate normal population indicated that this correlational model was inappropriate for the data. The lack of adequate mathematical models for the sampling distributions of item discrimination indices suggests that one should avoid indices whose only real reason for existence was the simplification of computational procedures.
Classical item analysis procedures were developed for dichotomously scored items and do not apply to items allowing multiple correct responses. Maximum likelihood procedures analogous to those employed in polychotomous bio-assay are presented which yield estimates of the sets of parameters for items having multiple nonordered responses. Expressions for the estimates of the asymptotic variances of the item parameters and on overall chi-square goodness of fit test are also provided.
The “Traveling Salesman” and similar combinatorial programming tasks encountered in operations research are discussed as possible data analysis models in psychology, for example, in developmental scaling, Guttman scaling, profile smoothing, and data array clustering. In addition, a short overview of the various computational approaches from this area of combinatorial optimization is included.
Estimates of test size (probability of Type I error) were obtained for several specific repeated measures designs. Estimates were presented for configurations where the underlying covariance matrices exhibited varying degrees of heterogeneity. Conventional variance ratios were employed as basic statistics in order to produce estimates of size for a conventional test, an ∊-adjusted test, and ∊-adjusted test and a conservative test. Indices for empirical distributions of two estimators of ∊j, a measure of covariance heterogeneity, were also provided.
Repeated measures designs have been widely employed in psychological experimentation, however, such designs have rarely been analyzed by means of permutation procedures. In the present paper certain aspects of hypothesis tests in a particular repeated measures design (one non-repeated factor (A) and one repeated factor (B) with K subjects per level of A) were investigated by means of permutation rather than sampling processes. The empirical size and power of certain normal theory F-tests obtained under permutation were compared to their nominal normal theory values. Data sets were established in which various combinations of kurtosis of subject means and intra-subject variance heterogeneity existed in order that their effect upon the agreement of these two models could be ascertained. The results indicated that except in cases of high intra-subject variance heterogeneity, the usual F-tests on B and AB exhibited approximately the same size and power characteristics whether based upon a permutation or normal theory sampling basis.
While a rotation procedure currently exists to maximize simultaneously Tucker's coefficient of congruence between corresponding factors of two factor matrices under orthogonal rotation of one factor matrix, only approximate solutions are known for the generalized case where two or more matrices are rotated. A generalization and modification of the existing rotation procedure to simultaneously maximize the congruence is described. An example using four data matrices, comparing the generalized congruence maximization procedure with alternative rotation procedures, is presented. The results show a marked improvement of the obtained congruence using the generalized congruence maximization procedure compared to other procedures, without a significant loss of success with respect to the least squares criterion. A computer program written by the author to perform the rotations is briefly discussed.
Procedures for assessing the invariance of factors found in data sets using different subjects and the same variables are often using the least squares criterion, which appears to be too restrictive for comparing factors.
Tucker's coefficient of congruence, on the other hand, is more closely related to the human interpretation of factorial invariance than the least squares criterion. A method maximizing simultaneously the sum of coefficients of congruence between two matrices of factor loadings, using orthogonal rotation of one matrix is presented. As shown in examples, the sum of coefficients of congruence obtained using the presented rotation procedure is slightly higher than the sum of coefficients of congruence using Orthogonal Procrustes Rotation based on the least squares criterion.