We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Edited by
Irene Cogliati Dezza, University College London,Eric Schulz, Max-Planck-Institut für biologische Kybernetik, Tübingen,Charley M. Wu, Eberhard-Karls-Universität Tübingen, Germany
Information-seeking is usually conceived of as gathering information to make better decisions by observing and sampling from the external world. But for humans and many other intelligent agents, much of that information, once gathered, is also stored to guide future decisions, necessitating mechanisms for seeking information in some form of inner space. Here we survey various types of evidence suggesting that strategies adapted for search in external spatial environments are also used to seek information internally from memory. These include foraging strategies such as area-restricted search, which adaptively balances exploitation of locally clustered resources with exploration for resources more widely dispersed. We also describe how internal search satisfies the predictions of external foraging theory via the Marginal Value Theorem and show how these predictions can be used to investigate individual differences in memory search such as those caused by aging and cognitive impairment. Finally, we consider evidence that the structure of inner space may be a result of the very processes we use to search it.
Evolution of cold dry snow and firn plays important roles in glaciology; however, the physical formulation of a densification law is still an active research topic. We forced eight firn-densification models and one seasonal-snow model in six different experiments by imposing step changes in temperature and accumulation-rate boundary conditions; all of the boundary conditions were chosen to simulate firn densification in cold, dry environments. While the intended application of the participating models varies, they are describing the same physical system and should in principle yield the same solutions. The firn models all produce plausible depth-density profiles, but the model outputs in both steady state and transient modes differ for quantities that are of interest in ice core and altimetry research. These differences demonstrate that firn-densification models are incorrectly or incompletely representing physical processes. We quantitatively characterize the differences among the results from the various models. For example, we find depth-integrated porosity is unlikely to be inferred with confidence from a firn model to better than 2 m in steady state at a specific site with known accumulation rate and temperature. Firn Model Intercomparison Experiment can provide a benchmark of results for future models, provide a basis to quantify model uncertainties and guide future directions of firn-densification modeling.
To describe the experiences of children and adolescents being screened positive for hypertrophic cardiomyopathy and how this impacts their daily life.
Background
Hypertrophic cardiomyopathy is a hereditary disease and the most common medical cause of sudden death in childhood and adolescence. This is the reason for recommending screening in children with an affected first-degree relative. A diagnosis of hypertrophic cardiomyopathy implies lifestyle modifications, restrictions that may bring profound changes to the daily life of the affected individual.
Design
This is a descriptive qualitative interview study.
Methods
We interviewed 13 asymptomatic children or adolescents diagnosed with hypertrophic cardiomyopathy through family screening 12–24 months after the diagnosis. Analysis was conducted with qualitative content analysis.
Results
Children described an involuntary change, which affected their daily life with limitations and restrictions in life, both in the individual and social context. Lifestyle recommendations had the most severe impact on daily life and affected their social context. They tried to navigate in a world with new references, and after reorientation they felt hope and had faith in the future.
Conclusions
Children diagnosed with hypertrophic cardiomyopathy through family screening went through an involuntary change resulting in limitations and restrictions in life. This study indicates that there is a need for support and that healthcare professionals have to consider the specific needs in these families. Our findings thus give guidance in how best to improve support to the patients and their family. Diagnosis in asymptomatic children should be accompanied by ideally multi-professional follow-up, focusing not only on medical issues.
Hypertrophic cardiomyopathy is hereditary and the commonest medical cause of sudden death in childhood and adolescence, which is the reason for recommending screening in children with an affected parent. A diagnosis of hypertrophic cardiomyopathy implies lifestyle modifications, restrictions that may bring profound changes to the affected individual and impacts on the whole family.
Objective
To describe parents’ experiences of how the diagnosis of hypertrophic cardiomyopathy in their child affects daily life.
Method
Twelve parents with asymptomatic children diagnosed with hypertrophic cardiomyopathy through family screening were interviewed 12–24 months after the diagnosis. Analysis was conducted with qualitative content analysis.
Results
Parents described the immediate reaction of shock, grief, and injustice but were also grateful that the child was still asymptomatic. The diagnosis caused a significant change in lifestyle for most families due mainly to restrictions of sports activities. Parents had to adapt to the new life and develop strategies to protect their child. Death became a reality causing feelings of vulnerability. Regular medical check-ups and access to the liaison nurse were described as important factors of reassurance.
Conclusions
Parents experienced early diagnosis as positive in a long-term perspective. The main changes perceived were ascribed to lifestyle modifications. Parents with athletic children experienced the lifestyle modifications as more severe. They strived to create a new life where they could feel secure and have faith in the future, and emphasised the need of regular follow-up and support from health care professionals as “mental pain relief”, which helped them achieve a new state of normality.
To describe the average consumption of carbohydrate-providing food groups among study centres of the European Prospective Investigation into Cancer and Nutrition (EPIC).
Methods:
Of the 27 redefined EPIC study centres, 19 contributed subjects of both genders and eight centres female participants only (men, n=13 031; women, n=22924, after exclusion of subjects under 35 and over 74 years of age from the original 36 900 total). Dietary data were obtained using the 24-hour recall methodology using the EPIC-SOFT software. The major sources of dietary carbohydrate were identified, and 16 food groups were examined.
Results:
The 10 food groups contributing most carbohydrate were bread; fruit; milk and milk products; sweet buns, cakes and pies; potato; sugar and jam; pasta and rice; vegetables and legumes; crispbread; and fruit and vegetable juices. Consumption of fruits as well as vegetables and legumes was higher in southern compared with northern centres, while soft drinks consumption was higher in the north. Italian centres had high pasta and rice consumption, but breakfast cereal, potato, and sweet buns, cakes and pies were higher in northern centres. In Sweden, lower bread consumption was balanced with a higher consumption of crispbread, and with sweet buns, cakes and pies. Overall, men consumed higher amounts of vegetables and legumes, bread, soft drinks, potatoes, pasta and rice, breakfast cereal and sugar and jam than women, but fruit consumption appeared more frequent in women.
Conclusion:
The study supports the established idea that carbohydrate-rich foods chosen in northern Europe are different from those in the Mediterranean region. When comparing and interpreting diet–disease relationships across populations, researchers need to consider all types of foods.
The resonant interaction of a narrow electron beam spiraling in a cold homogeneous magnetized plasma with electromagnetic cylindrical waves is considered. The conclusions derived in recent papers about the formation, in the presence of effective electromagnetic energy dissipation out of the radially bounded beam, of dynamically stable and longtime living bunches of resonant electrons in the developed stage of their nonlinear interaction with the waves are discussed in this paper for more general physical cases and for wider ranges of characteristic parameters. General analytical formulas for the excited electromagnetic fields, the radiated electromagnetic power flux and the linear growth rate as well as relevant numerical simulations results are presented.
A modified electron whistler dispersion law is derived in the cold-plasma approximation for analytical treatment and simplified numerical calculations of wave propagation in a wide range of ratios ωc/ωp of electron gyro- to plasma frequencies if the wave frequency is much less than ωp. The net contribution of ions to the wave dispersion law is expressed through the value of the lower-hybrid resonance frequency ωlhr only. This approximate dispersion law is valid in a wide frequency domain, that is, from the range of ωlhr until the domain where the contribution of ions can be neglected. A comparison of geometrical-optics ray trajectories calculated by the use of modified and total cold-plasma electron whistler dispersion laws is presented for the case of the Earth's plasma environment. Computer simulations of dynamical spectra of whistler waves excited by lightning discharges and registered in remote regions of the Earth's plasmasphere reveal good numerical stability of the developed ray-tracing code.
Undoped and Si-doped GaN films were grown by low pressure MOCVD on (0001) sapphire substrates. The angular distribution of the X-ray diffraction corresponding to the (0002), (0004), (100), (200), and (114) reflections has been measured by means of double- and triple -crystal diffractometry with Mo Kα1 and Cu Kα1 radiation under conditions of symmetrical and asymmetrical Bragg- and Laue-geometry. In our experiments a non-coplanar geometry was also applied. On the basis of the performed studies, five independent components of the tensor of microdistortion were evaluated and the average grain-size in two directions was determined. The type, position, and density of dislocations were established as well. The role of dislocations in strain relaxation and their influence on the optical and electrical properties are discussed.
In this study, both single undoped GaN epilayers and GaN-based device structures was treated by electrochemical etching in the dilute water solution of KOH or NaOH. Our investigations showed that in the undoped GaN epilayers grown by MOCVD the electrical and optical properties were nonuniform in depth. In this case, high defective and high conductive sublayer adjacent to the substrate was revealed by the electrochemical etching. This high conductive region was proved to condition the results of Hall effect measurements. Electrolyte etching of i-n GaN-based device structures grown by HVPE gave rise to significant increasing of the electroluminescence intensity. Influence of electrochemical etching on luminescence properties of the device structure is discussed.
We have measured the thermal conductivity λ and the compressibility of highly pure C70 in the range 90 to 450 K under pressures up to 1.2 GPa. Our results for the thermal conductivity indicate molecular rotation in C70 above 280 K at zero pressure. The phase boundary for the rotationally disordered phase has an approximate slope dT/dp = 75 K GPa−1. The bulk modulus B increases linearly with increasing p above 0.1 GPa, with an extrapolated zero pressure value at 296 K of B(0) = 8.3 GPa. Unexpected anomalies are found in both B and λ near 100 MPa, and we tentatively suggest that orientational ordering is responsible.
Recommend this
Email your librarian or administrator to recommend adding this to your organisation's collection.