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Previous research has found that measures of premorbid intellectual functioning may be predictive of performance on memory tasks among older adults (Duff, 2010). Intellectual functioning itself is correlated with education. The purpose of this study was to investigate the incremental validity of a measure of premorbid intellectual functioning over education levels to predict performance on the Virtual Environment Grocery Store (VEGS), which involves a simulated shopping experience assessing learning, memory, and executive functioning.
Participants and Methods:
Older adults (N = 118, 60.2% female, age 60-90, M = 73.51, SD = 7.46) completed the Wechsler Test of Adult Reading and the VEGS.
Results:
WTAR and education level explained 9.4% of the variance in VEGS long delay free recall, F = 5.97, p = 0.003). WTAR was a significant predictor (ß = 0.25, p = 0.006), while level of education was not.
Conclusions:
These results suggest that crystalized intelligence may benefit recall on a virtual reality shopping task.
iLookOut, a web-based child abuse training for early childcare professionals (ECPs), has been shown to improve knowledge and attitudes related to correctly identifying and reporting suspected cases of child abuse. The overarching goal of the present study is to examine “what works for whom” for iLookOut in order to identify strategies for optimizing learner outcomes.
Methods:
This prospective study enrolled 12,705 ECPs who completed iLookOut (November 2014–December 2018). We used structural equation models to test whether learner demographic and professional characteristics were differentially associated with implementation outcomes (i.e., acceptability and appropriateness) and whether these mediated subsequent indicators of training effectiveness (i.e., gains in knowledge).
Results:
Consistent with previous research, individuals with lower baseline knowledge scores showed greater knowledge gains (β = −.57; p < .001). Greater knowledge gains were seen for learners who reported higher acceptability (β = .08; p < .001) or appropriateness (β = .14; p < .001). Implementation outcomes strongly associated with knowledge gains included acceptability for female learners and appropriateness for learners who had not completed high school or had >15 years of experience in childcare settings. Where mediation was found, for the majority of groups, appropriateness emerged as the driving mediator.
Conclusion:
Implementation outcomes emerged as important drivers of knowledge change for most groups. The iLookOut Core Training’s use of a multimedia learning environment, video-based storylines, and game-based techniques were endorsed by learners and correlated with increases in knowledge. Future work should explore why aspects of the iLookOut training are rated as less acceptable or appropriate by some groups and what changes would improve efficacy for low performing learners.
Mental health needs and disparities are widespread and have been exacerbated by the COVID-19 pandemic, with the greatest burden being on marginalized individuals worldwide. The World Health Organization developed the Mental Health Gap Action Programme to address growing global mental health needs by promoting task sharing in the delivery of psychosocial and psychological interventions. However, little is known about the training needed for non-specialists to deliver these interventions with high levels of competence and fidelity. This article provides a brief conceptual overview of the evidence concerning the training of non-specialists carrying out task-sharing psychosocial and psychological interventions while utilizing illustrative case studies from Kenya, Ethiopia, and the United States to highlight findings from the literature. In this article, the authors discuss the importance of tailoring training to the skills and needs of the non-specialist providers and their roles in the delivery of an intervention. This narrative review with four case studies advocates for training that recognizes the expertise that non-specialist providers bring to intervention delivery, including how they promote culturally responsive care within their communities.
To characterise subjective symptoms in patients undergoing surgical repair of superior semicircular canal dehiscence.
Methods
Questionnaires assessing symptom severity and impact on function and quality of life were administered to patients before superior semicircular canal dehiscence surgery, between June 2011 and March 2016. Questionnaire sections included general quality of life, internal amplified sounds, dizziness and tinnitus, with scores of 0–100 points.
Results
Twenty-three patients completed the questionnaire before surgery. Section scores (mean±standard deviation) were: 38.2 ± 25.2 for general quality of life, 52.5 ± 23.9 for internal amplified sounds, 35.1 ± 28.8 for dizziness, 33.3 ± 30.7 for tinnitus, and 39.8 ± 22.2 for the composite score. Cronbach's α statistic averaged 0.93 (range, 0.84–0.97) across section scores, and 0.83 for the composite score.
Conclusion
The Gopen–Yang Superior Semicircular Canal Dehiscence Questionnaire provides a holistic, patient-centred characterisation of superior semicircular canal dehiscence symptoms. Internal consistency analysis validated the questionnaire and provided a quantitative framework for further optimisation in the clinical setting.
Host–parasite dynamics can play a fundamental role in both the establishment success of invasive species and their impact on native wildlife. The net impact of parasites depends on their capacity to switch effectively between native and invasive hosts. Here we explore host-switching, spatial patterns and simple fitness measures in a slow-expanding invasion: the invasion of Asian house geckos (Hemidactylus frenatus) from urban areas into bushland in Northeast Australia. In bushland close to urban edges, H. frenatus co-occurs with, and at many sites now greatly out-numbers, native geckos. We measured prevalence and intensity of Geckobia mites (introduced with H. frenatus), and Waddycephalus (a native pentastome). We recorded a new invasive mite species, and several new host associations for native mites and geckos, but we found no evidence of mite transmission between native and invasive geckos. In contrast, native Waddycephalus nymphs were commonly present in H. frenatus, demonstrating this parasite's capacity to utilize H. frenatus as a novel host. Prevalence of mites on H. frenatus decreased with distance from the urban edge, suggesting parasite release towards the invasion front; however, we found no evidence that mites affect H. frenatus body condition or lifespan. Waddycephalus was present at low prevalence in bushland sites and, although its presence did not affect host body condition, our data suggest that it may reduce host survival. The high relative density of H. frenatus at our sites, and their capacity to harbour Waddycephalus, suggests that there may be impacts on native geckos and snakes through parasite spillback.
Experiments were conducted to compare barnyardgrass control and rice injury and yield with emulsifiable concentrate and dry flowable formulations of propanil as single or repeat applications with crop oil concentrate, methylated seed oil, a blend of organosilicone surfactant and methylated seed oil or conventional nonionic surfactant, and organosilicone surfactant. Two applications of propanil were more effective in controlling barnyardgrass than a single application. The emulsifiable concentrate formulation of propanil controlled barnyardgrass more effectively than the dry flowable formulation in some but not all experiments. Differences in barnyardgrass control with propanil as influenced by adjuvants were minor and inconsistent. The most consistent barnyardgrass control and the highest rice yields were obtained with repeat applications of the emulsifiable concentrate formulation of propanil.
The ability to perform microbial detection and characterization in-field at extreme environments, rather than on returned samples, has the potential to improve the efficiency, relevance and quantity of data from field campaigns. To date, few examples of this approach have been reported. Therefore, we demonstrate that the approach is feasible in subglacial environments by deploying four techniques for microbial detection: real-time polymerase chain reaction; microscopic fluorescence cell counts, adenosine triphosphate bioluminescence assay and recombinant Factor C assay (to detect lipopolysaccharide). Each technique was applied to 12 subglacial ice samples, 12 meltwater samples and two snow samples from Engabreen, Northern Norway. Using this multi-technique approach, the detected biomarker levels were as expected, being highest in debris-rich subglacial ice, moderate in glacial meltwater and low in clean ice (debris-poor) and snow. Principal component analysis was applied to the resulting dataset and could be performed in-field to rapidly aid the allocation of resources for further sample analysis. We anticipate that in-field data collection will allow for multiple rounds of sampling, analysis, interpretation and refinement within a single field campaign, resulting in the collection of larger and more appropriate datasets, ultimately with more efficient science return.
The aim of this study was to estimate the amount of childhood hepatitis B virus transmission in children born in the UK, a very low-prevalence country, that is preventable only by universal hepatitis B immunization of infants. Oral fluid specimens were collected from schoolchildren aged 7–11 years in four inner city multi-ethnic areas and tested for the presence of antibody to hepatitis B core antigen (anti-HBc). Those found positive or indeterminate were followed up with testing on serum to confirm their hepatitis B status. The overall prevalence of anti-HBc in children was low [0·26%, 95% confidence interval (CI) 0·14–0·44]. The estimated average annual incidence of hepatitis B was estimated to be 29·26/100 000 children (95% CI 16·00–49·08). The total incidence that is preventable only by a universal infant immunization programme in the UK was estimated to be between 5·00 and 12·49/100 000. The study demonstrates that the extent of horizontal childhood hepatitis B virus transmission is low in children born in the UK and suggests that schools in the UK are an uncommon setting for the transmission of the virus. Targeted hepatitis B testing and immunization of migrants from intermediate- and high-prevalence countries is likely to be a more effective measure to reduce childhood transmission than a universal infant immunization programme.
There is a paucity of randomized controlled trials (RCTs) to evaluate models of palliative care. Although interventions vary, all have faced a variety of methodological challenges including adequate recruitment, missing data, and contamination of the control group. We describe the ENABLE II intervention, methods, and sample baseline characteristics to increase intervention and methodological transparency, and to describe our solutions to selected methodological issues.
Methods:
Half of the participants recruited from our rural U.S. comprehensive cancer center and affiliated clinics were randomly assigned to a phone-based, nurse-led educational, care coordination palliative care intervention model. Intervention services were provided to half of the participants weekly for the first month and then monthly until death, including bereavement follow-up call to the caregiver. The other half of the participants were assigned to care as usual. Symptoms, quality of life, mood, and functional status were assessed every 3 months until death.
Results:
Baseline data of 279 participants were similar to normative samples. Solutions to methodological challenges of recruitment, missing data, and “usual care” control group contamination are described.
Significance of results:
It is feasible to overcome many of the methodological challenges to conducting a rigorous palliative care RCT.
Assessments of radiation exposure of reptiles may be required in some countries as many species are protected. However, there are few data available for the transfer of radionuclides to them, especially in terrestrial ecosystems, and consequently, no specific peer reviewed reptile data have been used in the derivation of default transfer parameters in the ERICA Tool. Twenty samples of Lacerta agilis (sand lizard) and five of Natrix natrix (grass snake) were collected from two sites within the Chernobyl Exclusion Zone and analysed for Pu-isotopes, 137Cs and 90Sr. Corresponding activity concentrations for soil from the sampling sites were available. These data have been used to derive concentration ratios (CR) (i.e. reptile whole-body fresh weight activity concentration relative to the dry weight activity concentration in soil). CR values for N. natrix tended to be lower than those for L. agilis. The CR values derived in this paper will be used to improve the default values provided within the ERICA Tool. Whole-body activity concentrations determined in the reptile samples were broadly comparable with data available from the same sampling sites for small mammal species.
An assessment of the natural radiation dose to wildlife in England and Wales was made to determine the contribution it may make to the total radiation dose estimated during environmental impact assessments. Significant use was made of systematic datasets for environmental media (stream sediments, stream waters and soils), in particular those produced by the Geochemical Baseline Survey of the Environment (G-BASE) project. This provided extensive, although variable, coverage for different elements and sample types after normalisation of data to account for changes in sampling and analysis over time. Almost complete coverage for K in stream sediments was achieved by merging G-BASE and Wolfson Atlas data. This required normalisation of the Wolfson data to the G-BASE results. Coverage was improved greatly for U and Th in sediments, and K, U and Th in soils, by using the strong relationship between soils and sediments and geology (both solid and superficial) to extrapolate the data. The total U, Th and K data were used to derive activity concentrations of 238U and 232Th series radionuclides and 40K. External dose rates to wildlife were then estimated from derived media concentrations; internal dose rates were estimated from measured activities in biota or activities predicted using recommended concentration ratios.
There is general international acceptance of the need to demonstrate that the environment is protected from ionising radiation. In some countries requirements and guidelines for the protection of non-human biota are already in place. As a consequence a number of models and approaches have been proposed for the estimation of the exposure of non-human biota to ionising radiation. The IAEA EMRAS programme's Biota Working Group has conducted the most comprehensive intercomparison of the predictions of these approaches to date. In this paper, we present an overview of the activities of the Biota Working Group concentrating on its conclusions and recommendations.
We review collated data and available models for estimating the transfer of radionuclides to terrestrial biota within the European Arctic. The most abundant data are for radiocaesium and radiostrontium although many data for natural radionuclides are available. For some radionuclides no data are available for describing transfer to Arctic biota. Allometric-kinetic models have been used to estimate transfer for radionuclide-biota combinations. Predicted values were in good agreement with observed data for some radionuclides although less so for others. There are no bespoke models to enable the dynamic prediction of radionuclide transfer to Arctic biota. A human Arctic foodchain model has been adapted to estimate 137Cs and 90Sr transfer to some Arctic biota. There are many factors of Arctic ecosystems which may influence radionuclide behaviour including short growing seasons, prolonged soil freezing, and effects of low temperatures on biological rates. If exposure to ionising radiation in Arctic ecosystems is to be robustly predicted such factors must be fully understood and incorporated into models.
In this paper we use the FASSET framework to estimate absorbed dose rates for biota within the Chernobyl exclusion zone. The estimated doses are compared to observed biological effects within the Chernobyl exclusion zone and effects expected from summaries of existing knowledge and the extent of contamination. Although paucity of observations under conditions of chronic irradiation makes direct comparison difficult, the biological effects observed in the Chernobyl exclusion zone over the period considered here (1988-2003) are broadly in agreement with those which may have been expected.